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1. 发明授权

US07335514B2 Optical biosensor 失效
标题翻译：光学生物传感器
公开(公告)号：US07335514B2
公开(公告)日：2008-02-26
申请号：US10858370
申请日：2004-06-02
申请人： Valentina Grasso , Federica Valerio , Vito Guido Lambertini , Marco Pizzi , Piero Perlo
发明人： Valentina Grasso , Federica Valerio , Vito Guido Lambertini , Marco Pizzi , Piero Perlo
IPC分类号： G01N33/553
CPC分类号： G01N33/5438 , G01N21/76 , G01N33/54373 , G01N33/551 , G01N33/553
摘要： The present invention relates to an optical biosensor comprising a porous matrix. In the specific case, reference is made to anodized porous alumina, on the surface of which the biological component specific for the analyte in question is immobilized, and to an optical-signal detector connected to said matrix. The present patent further relates to a biosensor having the porous matrix and the optical detector integrated in a single structure, in particular to biosensors with porous matrix other than porous alumina, for example porous silicon.
摘要翻译：本发明涉及一种包括多孔基质的光学生物传感器。在具体情况下，参考阳极氧化多孔氧化铝，其表面上固定有关分析物的生物成分，以及连接到所述基质的光信号检测器。本发明进一步涉及一种生物传感器，其具有集成在单一结构中的多孔基质和光学检测器，特别是涉及具有多孔氧化铝以外的多孔基质的生物传感器，例如多孔硅。

2. 发明授权

US07858398B2 Optical biosensor 失效
标题翻译：光学生物传感器
公开(公告)号：US07858398B2
公开(公告)日：2010-12-28
申请号：US11962816
申请日：2007-12-21
申请人： Valentina Grasso , Federica Valerio , Vito Guido Lambertini , Marco Pizzi , Piero Perlo
发明人： Valentina Grasso , Federica Valerio , Vito Guido Lambertini , Marco Pizzi , Piero Perlo
IPC分类号： G01N33/553
CPC分类号： G01N33/5438 , G01N21/76 , G01N33/54373 , G01N33/551 , G01N33/553
摘要： The present invention relates to an optical biosensor comprising a porous matrix. In the specific case, reference is made to anodized porous alumina, on the surface of which the biological component specific for the analyte in question is immobilized, and to an optical-signal detector connected to said matrix. The present patent further relates to a biosensor having the porous matrix and the optical detector integrated in a single structure, in particular to biosensors with porous matrix other than porous alumina, for example porous silicon.
摘要翻译：本发明涉及一种包括多孔基质的光学生物传感器。在具体情况下，参考阳极氧化多孔氧化铝，其表面上固定有关分析物的生物成分，以及连接到所述基质的光信号检测器。本发明进一步涉及一种生物传感器，其具有集成在单一结构中的多孔基质和光学检测器，特别是具有多孔氧化铝以外的多孔基质的生物传感器，例如多孔硅。

3. 发明申请

US20080118973A1 OPTICAL BIOSENSOR 失效
标题翻译：光学生物传感器
公开(公告)号：US20080118973A1
公开(公告)日：2008-05-22
申请号：US11962816
申请日：2007-12-21
申请人： Valentina Grasso , Federica Valerio , Vito Guido Lambertini , Marco Pizzi , Piero Perlo
发明人： Valentina Grasso , Federica Valerio , Vito Guido Lambertini , Marco Pizzi , Piero Perlo
IPC分类号： C12M1/00
CPC分类号： G01N33/5438 , G01N21/76 , G01N33/54373 , G01N33/551 , G01N33/553
摘要： The present invention relates to an optical biosensor comprising a porous matrix. In the specific case, reference is made to anodized porous alumina, on the surface of which the biological component specific for the analyte in question is immobilized, and to an optical-signal detector connected to said matrix. The present patent further relates to a biosensor having the porous matrix and the optical detector integrated in a single structure, in particular to biosensors with porous matrix other than porous alumina, for example porous silicon.
摘要翻译：本发明涉及一种包括多孔基质的光学生物传感器。在具体情况下，参考阳极氧化多孔氧化铝，其表面上固定有关分析物的生物成分，以及连接到所述基质的光信号检测器。本发明进一步涉及一种生物传感器，其具有集成在单一结构中的多孔基质和光学检测器，特别是具有多孔氧化铝以外的多孔基质的生物传感器，例如多孔硅。

4. 发明授权

US07086637B2 Radiofrequency-controlled device for release/sampling of substances 失效
标题翻译：用于物质释放/取样的射频控制装置
公开(公告)号：US07086637B2
公开(公告)日：2006-08-08
申请号：US10853112
申请日：2004-05-26
申请人： Piero Perlo , Anatoli Zvezdine , Valentina Grasso , Federica Valerio , Vito Guido Lambertini , Daniele Pullini , Nello Li Pira , Piermario Repetto , Gianfranco Innocenti
发明人： Piero Perlo , Anatoli Zvezdine , Valentina Grasso , Federica Valerio , Vito Guido Lambertini , Daniele Pullini , Nello Li Pira , Piermario Repetto , Gianfranco Innocenti
IPC分类号： F16K31/02
CPC分类号： A61B10/0045 , A61K9/0009 , A61M37/00 , A61M2205/0266 , A61M2205/128 , A61M2205/3584 , A61M2205/8206
摘要： The present invention relates to a miniaturized device controlled by electromagnetic signals in the radiofrequency range for controlled release of substances or for controlled sampling of specimens, comprising a reservoir, and a closing system associated to said reservoir, where said closing system is constituted by a valve structure, closing-opening of which is controlled by the electromagnetic signal in the radiofrequency range.
摘要翻译：本发明涉及一种由射频范围内的电磁信号控制的小型化装置，用于物质的控制释放或用于受控取样的样品，包括储存器和与所述储存器相关联的封闭系统，其中所述封闭系统由阀结构，其闭合开度由射频范围内的电磁信号控制。

5. 发明申请

US20050019799A1 Optical biosensor 失效
标题翻译：光学生物传感器
公开(公告)号：US20050019799A1
公开(公告)日：2005-01-27
申请号：US10858370
申请日：2004-06-02
申请人： Valentina Grasso , Federica Valerio , Vito Lambertini , Marco Pizzi , Piero Perlo
发明人： Valentina Grasso , Federica Valerio , Vito Lambertini , Marco Pizzi , Piero Perlo
IPC分类号： G01N21/76 , G01N33/543 , G01N33/553 , C12Q1/68 , C12M1/34
CPC分类号： G01N33/5438 , G01N21/76 , G01N33/54373 , G01N33/551 , G01N33/553
摘要： The present invention relates to an optical biosensor comprising a porous matrix. In the specific case, reference is made to anodized porous alumina, on the surface of which the biological component specific for the analyte in question is immobilized, and to an optical-signal detector connected to said matrix. The present patent further relates to a biosensor having the porous matrix and the optical detector integrated in a single structure, in particular to biosensors with porous matrix other than porous alumina, for example porous silicon.
摘要翻译：本发明涉及一种包括多孔基质的光学生物传感器。在具体情况下，参考阳极氧化多孔氧化铝，其表面上固定有关分析物的生物成分，以及连接到所述基质的光信号检测器。本发明进一步涉及一种生物传感器，其具有集成在单一结构中的多孔基质和光学检测器，特别是具有多孔氧化铝以外的多孔基质的生物传感器，例如多孔硅。

6. 发明申请

US20070155005A1 Chemical biological device for display and light emission 审中-公开
标题翻译：用于显示和发光的化学生物装置
公开(公告)号：US20070155005A1
公开(公告)日：2007-07-05
申请号：US11641771
申请日：2006-12-20
申请人： Frederica Valerio , Valentina Grasso , Vito Guido Lambertini , Marzia Paderi , Piermario Repetto , Piero Perlo
发明人： Frederica Valerio , Valentina Grasso , Vito Guido Lambertini , Marzia Paderi , Piermario Repetto , Piero Perlo
IPC分类号： C12M1/34
CPC分类号： G01N21/76
摘要： The present invention concerns a display device comprising: at least one micro-reaction-chamber (2) to which is associated an inlet (3a) to receive a reaction liquid and an outlet (4b) to discharge the product of reaction; at least one charge micro-channel (3) connected to said inlet (3a) and at least one discharge micro-channel (4) connected to said outlet (4b); a porous substratum (2a) situated inside said micro-reaction-chamber (2); at least one chemical and/or biological element (22) immobilised on the porous substratum (2a) capable of generating light emission when in contact with the reaction liquid.
摘要翻译：本发明涉及一种显示装置，包括：至少一个微反应室（2），其与入口（3a）相关联以接收反应液体和出口（4b）以排出反应产物; 连接到所述入口（3a）的至少一个充电微通道（3）和连接到所述出口（4b）的至少一个放电微通道（4）; 位于所述微反应室（2）内的多孔基底（2a）; 至少一个固定在多孔基底（2a）上的化学和/或生物元件（22），其能够在与反应液体接触时产生光发射。

7. 发明授权

US07098775B2 System to avoid the collision of a vehicle with animals 有权
标题翻译：避免车辆与动物碰撞的系统
公开(公告)号：US07098775B2
公开(公告)日：2006-08-29
申请号：US10502571
申请日：2003-09-29
申请人： Piero Perlo , Valentina Grasso , Federica Valerio
发明人： Piero Perlo , Valentina Grasso , Federica Valerio
IPC分类号： G08B3/10
CPC分类号： A01M29/18 , A01M31/002 , G08G1/16 , G08G1/166
摘要： A system and a method avoids the collision of a vehicle with animals tending to cross the road before the moving vehicle. Such system comprises a visual system directly actuating a RF emitter, or more RF emitters, emitting directional sound waves with a frequency above 25,000 Hz. Sound waves are directed frontally though with a frequency decreasing from the center of the roadway towards the road edge, so as to lead the animal to move towards the road edge.
摘要翻译：一种系统和方法避免车辆与移动车辆之前横穿道路的动物碰撞。这种系统包括直接致动RF发射器的视觉系统，或更多的RF发射器，发射频率高于25,000Hz的定向声波。虽然声波的频率从巷道的中心朝向道路边缘的频率逐渐向前引导，从而引导动物向着路边移动。

8. 发明申请

US20050116828A1 System to avoid the collision of a vehicle with animals 有权
标题翻译：避免车辆与动物碰撞的系统
公开(公告)号：US20050116828A1
公开(公告)日：2005-06-02
申请号：US10502571
申请日：2003-09-29
申请人： Piero Perlo , Valentina Grasso , Federica Valerio
发明人： Piero Perlo , Valentina Grasso , Federica Valerio
IPC分类号： A01M29/18 , A01M31/00 , G08G1/16 , G08B23/00
CPC分类号： A01M29/18 , A01M31/002 , G08G1/16 , G08G1/166
摘要： The invention discloses a system and a method to avoid the collision of a vehicle with animals tending to cross the road before the moving vehicle. Such system comprises a visual system directly actuating a RF emitter, or more RF emitters, emitting directional sound waves with a frequency above 25,000 Hz. Sound waves are directed frontally though with a frequency decreasing from the center of the roadway towards the road edge, so as to lead the animal to move towards the road edge.
摘要翻译：本发明公开了一种系统和方法，用于避免车辆与移动车辆之前横穿道路的动物碰撞。这种系统包括直接致动RF发射器的视觉系统，或更多的RF发射器，发射频率高于25,000Hz的定向声波。虽然声波的频率从巷道的中心朝向道路边缘的频率逐渐向前引导，从而引导动物向着路边移动。

9. 发明授权

US07460998B2 Voice connection system between humans and animals 失效
标题翻译：人与动物之间的语音连接系统
公开(公告)号：US07460998B2
公开(公告)日：2008-12-02
申请号：US10691527
申请日：2003-10-24
申请人： Piero Perlo , Valentina Grasso , Federica Valerio
发明人： Piero Perlo , Valentina Grasso , Federica Valerio
IPC分类号： G10L21/00 , A61B5/00
CPC分类号： G10L17/26 , A01K15/02 , A01K15/021 , G10L13/00
摘要： A voice connection system comprises a sensor matrix sending to a control unit signals indicating an animal's status in terms of stimuli, feelings, events, actions or behavior of said animal. The control unit selects—depending on the signals received—a voice message recorded into memory means associated to the unit, and activates a loudspeaker belonging to the system, in order to issue said voice message. The system further comprises voice recognition means, which activate pulse generators depending on the content of a voice message uttered by the human user.
摘要翻译：语音连接系统包括传感器矩阵向控制单元发送指示动物在所述动物的刺激，感觉，事件，动作或行为方面的状态的信号。控制单元根据所接收的信号选择记录在与该单元相关联的存储装置中的语音消息，并激活属于系统的扬声器，以便发出所述语音消息。该系统还包括语音识别装置，其根据人类用户发出的语音消息的内容激活脉冲发生器。

10. 发明申请

US20050256465A1 Shape memory shutter device 失效
标题翻译：形状记忆快门装置
公开(公告)号：US20050256465A1
公开(公告)日：2005-11-17
申请号：US11116227
申请日：2005-04-28
申请人： Piero Perlo , Valentina Grasso
发明人： Piero Perlo , Valentina Grasso
IPC分类号： A61F2/00 , A61F2/02 , A61F5/00 , A61F5/44 , A61F5/451 , A61F13/20 , A61M1/00
CPC分类号： A61F2/0022 , A61F5/0093 , A61F5/451 , A61F2210/0014 , A61F2250/0001
摘要： A shape memory shutter device for controlling the rectum of a disabled person, comprising a section of conduit to be connected to the rectum of the disabled person, shutter means which control the passage through the conduit section and shape memory actuator means for actuating said shutter means. The shutter means comprise a plurality of petals positioned circumferentially around said conduit section and able to move between a closed and an open position. The actuator means preferably comprise shape memory wires, for example associated directly to the petals and means for supplying an electrical current through said wires to cause its opening. Preferably, sensors of the presence of material to be evacuated within the device are provided, to generate an alarm signal that can be detected by the patient. The patient can thus positively command the opening of the shutter device. In the case of a completely disabled patient, the opening of the shutter device can be obtained automatically as a result of the detection of material to be evacuated, in which case to the device is associated a disposable pouch for the collection of the evacuated material.
摘要翻译：一种用于控制残疾人的直肠的形状记忆快门装置，包括要连接到残疾人的直肠的导管部分，控制通过导管部分的通道的快门装置和用于致动所述快门装置的形状记忆致动器装置。快门装置包括围绕所述导管部分周向设置并能够在关闭位置和打开位置之间移动的多个花瓣。致动器装置优选地包括例如与花瓣直接相关联的形状记忆线，以及用于通过所述线提供电流以使其开口的装置。优选地，提供了在装置内被抽空的材料的存在的传感器，以产生可由患者检测的报警信号。因此，患者可以肯定地指示快门装置的打开。在完全残疾的患者的情况下，由于检测要抽真空的材料，可以自动获得快门装置的打开，在这种情况下，该装置与用于收集抽空材料的一次性袋相关联。

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