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1. 发明申请

US20130191100A1 BLOOD FLOW COMPUTATION IN VESSELS WITH IMPLANTED DEVICES 有权
标题翻译：血管流动计算在具有植入装置的血管中
公开(公告)号：US20130191100A1
公开(公告)日：2013-07-25
申请号：US13744857
申请日：2013-01-18
申请人： Viorel Mihalef , Puneet Sharma , Thomas Redel , Ali Kamen
发明人： Viorel Mihalef , Puneet Sharma , Thomas Redel , Ali Kamen
IPC分类号： G06F19/00
CPC分类号： G16H50/50 , A61B6/032 , A61B6/486 , A61B6/504 , A61B6/5217 , G06T19/00 , G06T2210/41
摘要： A method for modeling blood flow through a flow diverter includes receiving a medical image containing blood vessels. Vessel geometry is extracted from the received medical image. Inlets and outlets are tagged within the extracted vessel geometry. A desired flow diverter is selected. A model of the selected flow diverter is generated within the imaged blood vessel, the model representing the flow diverter as a tube having a porous surface characterized by a viscous resistance and an inertial resistance. A course of blood flow though the flow diverter is predicted based on the generated model, the extracted vessel geometry, and the tagged inlets and outlets.
摘要翻译：通过流转向器对血液流动进行建模的方法包括接收包含血管的医学图像。从接收到的医学图像中提取血管几何。进口和出口在提取的容器几何中被标记。选择所需的分流器。所选流量分流器的模型在成像的血管内产生，该模型表示流量分流器为具有以粘性阻力和惯性阻力为特征的多孔表面的管。基于生成的模型，提取的血管几何形状和标记的入口和出口预测通过流量分流器的血液流动过程。

2. 发明授权

US08965084B2 Blood flow computation in vessels with implanted devices 有权
标题翻译：带有植入装置的血管中的血流计算
公开(公告)号：US08965084B2
公开(公告)日：2015-02-24
申请号：US13744857
申请日：2013-01-18
申请人： Viorel Mihalef , Puneet Sharma , Thomas Redel , Ali Kamen
发明人： Viorel Mihalef , Puneet Sharma , Thomas Redel , Ali Kamen
IPC分类号： G06K9/00 , G06K9/36 , G06F19/00 , G06T19/00 , A61B6/03 , A61B6/00
CPC分类号： G16H50/50 , A61B6/032 , A61B6/486 , A61B6/504 , A61B6/5217 , G06T19/00 , G06T2210/41
摘要： A method for modeling blood flow through a flow diverter includes receiving a medical image containing blood vessels. Vessel geometry is extracted from the received medical image. Inlets and outlets are tagged within the extracted vessel geometry. A desired flow diverter is selected. A model of the selected flow diverter is generated within the imaged blood vessel, the model representing the flow diverter as a tube having a porous surface characterized by a viscous resistance and an inertial resistance. A course of blood flow though the flow diverter is predicted based on the generated model, the extracted vessel geometry, and the tagged inlets and outlets.
摘要翻译：通过流转向器对血液流动进行建模的方法包括接收包含血管的医学图像。从接收到的医学图像中提取血管几何。进口和出口在提取的容器几何中被标记。选择所需的分流器。所选流量分流器的模型在成像的血管内产生，该模型表示流量分流器为具有以粘性阻力和惯性阻力为特征的多孔表面的管。基于生成的模型，提取的血管几何形状和标记的入口和出口预测通过流量分流器的血液流动过程。

3. 发明申请

US20140024932A1 Computation of Hemodynamic Quantities From Angiographic Data 有权
标题翻译：血管造影数据计算血流动力学数据
公开(公告)号：US20140024932A1
公开(公告)日：2014-01-23
申请号：US13937313
申请日：2013-07-09
申请人： Puneet Sharma , Xudong Zheng , Ali Kamen , Lucian Mihai Itu , Bogdan Georgescu , Dorin Comaniciu , Thomas Redel , Saikiran Rapaka , Viorel Mihalef
发明人： Puneet Sharma , Xudong Zheng , Ali Kamen , Lucian Mihai Itu , Bogdan Georgescu , Dorin Comaniciu , Thomas Redel , Saikiran Rapaka , Viorel Mihalef , Jan Boese
IPC分类号： A61B6/00
CPC分类号： A61B5/7278 , A61B5/02007 , A61B5/02028 , A61B5/021 , A61B5/026 , A61B6/481 , A61B6/504 , A61B6/507 , A61B6/5217 , A61B2019/524 , A61B2560/0475 , G06F19/00 , G16H50/50
摘要： Methods for computing hemodynamic quantities include: (a) acquiring angiography data from a patient; (b) calculating a flow and/or calculating a change in pressure in a blood vessel of the patient based on the angiography data; and (c) computing the hemodynamic quantity based on the flow and/or the change in pressure. Systems for computing hemodynamic quantities and computer readable storage media are described.
摘要翻译：用于计算血液动力学量的方法包括：（a）从患者获取血管造影数据; （b）基于血管造影数据计算流量和/或计算患者血管中的压力变化; 和（c）基于流量和/或压力变化来计算血流动力学量。描述了用于计算血液动力学量的系统和计算机可读存储介质。

4. 发明授权

US10555712B2 Segmenting an angiography using an existing three-dimensional reconstruction 有权
公开(公告)号：US10555712B2
公开(公告)日：2020-02-11
申请号：US15687272
申请日：2017-08-25
申请人： Thomas Redel
发明人： Thomas Redel
IPC分类号： A61B6/00 , G06T7/11 , G06T7/30 , G06T7/174 , A61B5/055 , G06T7/00 , G06T11/00 , A61B6/03
摘要： A method for segmenting a two-dimensional angiographic recording of a vessel of a body using a computing apparatus includes providing a three-dimensional reconstruction of the vessel of the body to the computing apparatus. The two-dimensional angiographic recording of the vessel of the body is provided on the computing apparatus. The three-dimensional reconstruction of the vessel of the body is registered with the two-dimensional recording of the vessel of the body. Spatial information of the three-dimensional reconstruction is projected onto the two-dimensional recording, and the two-dimensional recording is segmented using the spatial information projected onto the two-dimensional recording.

5. 发明授权

US10390782B2 Device and method for ascertaining at least one individual fluid-dynamic characteristic parameter of a stenosis in a vascular segment having serial stenoses 有权
公开(公告)号：US10390782B2
公开(公告)日：2019-08-27
申请号：US15451575
申请日：2017-03-07
申请人： Klaus Klingenbeck , Thomas Redel , Michael Scheuering , Michael Wiets
发明人： Klaus Klingenbeck , Thomas Redel , Michael Scheuering , Michael Wiets
IPC分类号： A61B6/00 , G06T7/11 , A61B6/03 , G06T7/00 , G16H50/50 , A61B34/10 , A61B5/02
摘要： The disclosure relates to a device and a method for ascertaining at least one individual fluid-dynamic characteristic parameter of a stenosis in a vascular segment having a plurality of serial stenoses, wherein angiography image data of the vascular segment is received from an angiography recording device, geometry data of the vascular segment is ascertained by an analysis device based on the angiography image data and combined into a segment model. At least one division point located between two of the stenoses respectively is ascertained by a dividing device in the segment model, the segment model is subdivided into subsegment models at each of the at least one division points, and the respective fluid-dynamic characteristic parameter is ascertained by a simulation device for at least one of the subsegment models based on respective geometry data of the subsegment model.

6. 发明授权

US10245001B2 Generation of a three-dimensional reconstruction of a body part by an X-ray machine 有权
公开(公告)号：US10245001B2
公开(公告)日：2019-04-02
申请号：US15614838
申请日：2017-06-06
申请人： Thomas Redel , Michael Scheuering
发明人： Thomas Redel , Michael Scheuering
IPC分类号： A61B6/02 , A61B6/00 , A61B6/08 , A61B6/04
摘要： The disclosure relates to an X-ray machine and a method for the operation of the X-ray machine for generation of a three-dimensional reconstruction of a body part. The method includes supplying a first X-ray capture of the body part; an automatic analysis of the first X-ray capture; an evaluation of the suitability of at least one further capture angle by the computing unit in the light of a result from the automatic analysis; setting of a second capture angle on the X-ray machine, either automatically by the computing unit or manually by an operator; a manually controlled approach to the set second capture angle by a capture unit of the X-ray machine; and capture of the second X-ray capture from the approached second capture angle by the capture unit to provide an improved method for operation of an X-ray machine for generation of a three-dimensional reconstruction of a body part.

7. 发明申请

US20180125583A1 TREATMENT PLANNING FOR A STENOSIS IN A VASCULAR SEGMENT BASED ON VIRTUAL HEMODYNAMIC ANALYSIS 审中-公开
公开(公告)号：US20180125583A1
公开(公告)日：2018-05-10
申请号：US15809473
申请日：2017-11-10
申请人： Thomas Redel
发明人： Thomas Redel
IPC分类号： A61B34/10 , A61B6/00 , G06F19/00
CPC分类号： A61B34/10 , A61B6/504 , A61B6/507 , A61B6/5217 , A61B6/5241 , A61B6/5247 , A61B8/06 , A61B8/488 , A61B2034/104 , A61B2034/105 , A61B2090/367 , A61B2090/376 , G16H20/40 , G16H30/40 , G16H50/50
摘要： A method for planning treatment of a stenosis in a vascular segment includes providing a geometric description of the vascular segment on a computer and determining a course of a hemodynamic parameter of the vascular segment along the vascular segment based on the geometric description provided by the computer. The computer calculates a mathematical derivative of the hemodynamic parameter over the length of the vascular segment along the vascular segment. At least one length section is specified for the vascular segment, and a value of the hemodynamic parameter in a distal end region of the vascular segment is simulated for a treatment device introduced virtually into the specified length section as a function of the mathematical derivative. The treatment of the stenosis including the introduction of the treatment device into the specified length section is planned as a function of the simulated value for the hemodynamic parameter.

8. 发明申请

US20180061114A1 ANGULATION PLANNING FOR A THREE DIMENSIONAL ANGIOGRAPHY 审中-公开
公开(公告)号：US20180061114A1
公开(公告)日：2018-03-01
申请号：US15685786
申请日：2017-08-24
申请人： Thomas Redel
发明人： Thomas Redel
IPC分类号： G06T15/08 , G06T7/33 , A61B6/00
CPC分类号： G06T15/08 , A61B6/032 , A61B6/504 , A61B6/5241 , A61B90/00 , A61B90/36 , A61B2090/367 , G06T7/337 , G06T2207/10116 , G06T2207/20224 , G06T2207/30048 , G06T2207/30101
摘要： A method and system for operating an x-ray device for a creation of a three-dimensional angiography of a body vessel segment. A three-dimensional reconstruction of the body vessel segment is provided to a computing device of the x-ray device. A center line of the body vessel segment is computed. An axis of rotation is laid through the center line. The three-dimensional reconstruction is registered with the x-ray device. The suitability of at least one recording angle pair with a first and a second recording angle for the creation of the three-dimensional angiography is assessed on the basis of an assessment criterion by the computing device. One of the at least one assessed recording angle pairs is selected for creation of the three-dimensional angiography as a function of a result of the assessment, in order to improve the creation of the three-dimensional angiography.

9. 发明申请

US20140094680A1 ANGIOGRAPHIC EXAMINATION METHOD FOR THE REPRESENTATION OF FLOW PROPERTIES 有权
标题翻译：用于表示流动性质的图像检查方法
公开(公告)号：US20140094680A1
公开(公告)日：2014-04-03
申请号：US14027294
申请日：2013-09-16
申请人： Markus Kowarschik , Thomas Redel
发明人： Markus Kowarschik , Thomas Redel
IPC分类号： A61B5/026
CPC分类号： A61B5/026 , A61B6/4458 , A61B6/4464 , A61B6/507
摘要： An angiographic examination method for the representation of flow properties of vessels of an object under examination is presented. To determine blood-flow parameters in 3-D with high temporal resolution, at least one 4-D DSA sequence is acquired for the generation of measurement-based 4-D DSA data sets. A model-based method determines time-dependent volume data sets, which, in terms of time, lie between the time-dependent volume data sets of the measurement-based 4-D DSA method.
摘要翻译：提出了一种用于表示被检查物体的血管的流动特性的血管造影检查方法。为了以高时间分辨率确定3-D中的血流参数，获取至少一个4-D DSA序列用于产生基于测量的4-D DSA数据集。基于模型的方法确定时间依赖的体数据集，其在时间上位于基于测量的4-D DSA方法的时间依赖的体数据集之间。

10. 发明授权

US08553832B2 Device for obtaining perfusion images 有权
标题翻译：用于获得灌注图像的装置
公开(公告)号：US08553832B2
公开(公告)日：2013-10-08
申请号：US11804903
申请日：2007-05-21
申请人： Estelle Camus , Thomas Redel , Martin Ostermeier , Oliver Meissner
发明人： Estelle Camus , Thomas Redel , Martin Ostermeier , Oliver Meissner
IPC分类号： A61B6/00
CPC分类号： A61B6/504 , A61B6/481 , A61B6/503 , A61B6/507 , G06F19/00 , G06F19/321
摘要： A system and method for obtaining perfusion images is disclosed. The system and method includes hardware and software for determining physiological characteristics of a patient and determining imaging parameter values for an imaging modality based on the patient's physiological characteristics. The system also includes a controller operative to receive the imaging parameter values for controlling an X-ray device. The X-ray device is coupled with the controller and acquires projection images of the patient, and outputs the projection images to a perfusion evaluation computer for evaluating the perfusion of an region of interest represented in the projection images. The perfusion rate of the region of interest is then output to an output device, such as a display or printer.
摘要翻译：公开了一种用于获得灌注图像的系统和方法。该系统和方法包括用于确定患者的生理特征的硬件和软件，并且基于患者的生理特征确定成像模态的成像参数值。该系统还包括可操作以接收用于控制X射线装置的成像参数值的控制器。 X射线装置与控制器耦合并获取患者的投影图像，并将投影图像输出到灌注评估计算机，以评估在投影图像中表示的感兴趣区域的灌注。然后将感兴趣区域的灌注速率输出到诸如显示器或打印机的输出装置。

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