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1. 发明授权

US10034681B2 Fluid communication features for Eustachian tube dilation instrument 有权
公开(公告)号：US10034681B2
公开(公告)日：2018-07-31
申请号：US14928114
申请日：2015-10-30
申请人： Acclarent, Inc.
发明人： Randy S. Chan , Siddhi K. Desai , Ketan P. Muni , Hung V. Ha , Andrew Drake
IPC分类号： A61F11/00 , A61B17/24 , A61M29/00 , A61M29/02 , A61B17/00 , A61M25/00
CPC分类号： A61B17/24 , A61B2017/00336 , A61B2017/00367 , A61B2017/00424 , A61B2017/00787 , A61F11/002 , A61M25/0041 , A61M25/0097 , A61M29/00 , A61M29/02 , A61M2210/0675
摘要： A system for dilating a Eustachian tube (ET) of a patient includes a guide member and a dilation catheter. The guide member includes a bent distal portion that is configured to provide access to an opening in the ET. The dilation catheter is slidable relative to the guide member. The dilation catheter includes a shaft, an expandable element, and an actuator. The expandable element is disposed at the distal portion of the shaft. The actuator includes a grasping portion and an actuating member. The expandable element is configured to transition to an expanded configuration in response to actuation of the actuating member. The grasping portion and actuating member are configured to be grasped in a single hand of an operator to enable the operator to advance the dilation catheter relative to the guide member and to transition the expandable element between expanded and unexpanded configurations with the single hand.

2. 发明授权

US09955852B2 Guide catheter with image capture and light emission features 有权
公开(公告)号：US09955852B2
公开(公告)日：2018-05-01
申请号：US14826400
申请日：2015-08-14
申请人： Acclarent, Inc.
发明人： Randy J. Kesten , Ketan P. Muni , James Patrick Garvey, II , Hung V. Ha , Andy Nguyen
IPC分类号： A61B1/00 , A61B1/05 , A61B1/06 , A61B1/227 , A61B17/29 , A61B1/012 , A61B1/018 , A61B1/233 , A61B17/24 , A61M25/01 , A61M25/10 , A61B1/04 , A61B17/00 , A61M29/02 , A61M25/06
CPC分类号： A61B1/00082 , A61B1/00087 , A61B1/00135 , A61B1/012 , A61B1/018 , A61B1/05 , A61B1/0623 , A61B1/0684 , A61B1/227 , A61B1/233 , A61B17/24 , A61B17/29 , A61B17/3421 , A61B90/361 , A61B2017/00331 , A61B2017/00787 , A61B2017/345 , A61B2090/306 , A61M25/0041 , A61M25/0054 , A61M25/0068 , A61M25/01 , A61M25/0662 , A61M25/10 , A61M29/02 , A61M2025/0046 , A61M2025/0681 , A61M2029/025 , A61M2205/32 , A61M2210/0675 , A61M2210/0681
摘要： A dilation catheter system comprises a guide member, a dilation catheter, and an image sensor. The guide member includes a shaft comprising a distal end and a proximal end. The shaft further defines a longitudinal axis. The dilation catheter is movable relative to the guide catheter member and comprises an expandable dilator. The expandable dilator is sized to fit within one or both of a Eustachian tube or a passageway associated with a paranasal sinus. The image sensor is configured to provide visualization within anatomy of a patient. The image sensor is integral with the guide member.

3. 发明申请

US20180110968A1 ACTUATION FEATURES FOR DILATION SYSTEM 审中-公开
公开(公告)号：US20180110968A1
公开(公告)日：2018-04-26
申请号：US15333620
申请日：2016-10-25
申请人： Acclarent, Inc.
发明人： Don Q. Ngo-Chu , George L. Matlock
IPC分类号： A61M29/02 , A61M25/09 , A61M25/10 , A61M25/01
CPC分类号： A61M29/02 , A61B17/22031 , A61B17/24 , A61B34/00 , A61B2017/00017 , A61B2017/00022 , A61B2017/22034 , A61B2017/22038 , A61B2090/065 , A61M25/0113 , A61M25/0136 , A61M25/09041 , A61M25/10182 , A61M2025/0681 , A61M2029/025 , A61M2210/0675 , A61M2210/0681
摘要： An apparatus includes a handle, a guide member, a dilation catheter, a guidewire, and first and second movement assemblies. The dilation catheter is slidably housed within the handle and is slidable relative to the guide member. The guidewire is translatable relative to the dilation catheter. The first movement assembly is configured to actuate relative to the handle and includes a first body fixed with the dilation catheter and a first coupling member. The second movement assembly is proximal in relation to the first movement assembly and includes a second body and a second coupling member. The second body is configured to selectively fix to the guidewire and actuate relative to the handle. The first coupling member and the second coupling member are configured to connect the first movement assembly and the second movement assembly to translate together relative to handle in response to distal translation of the first movement assembly.

4. 发明授权

US09078783B2 Silent effusion removal 有权
标题翻译：静脉积液去除
公开(公告)号：US09078783B2
公开(公告)日：2015-07-14
申请号：US12645339
申请日：2009-12-22
申请人： John H. Morriss , Greg Liu , Rohit Girotra , Tom Thanh Vo , Richard Roy Newhauser, Jr. , Thomas Jenkins , Joshua Makower
发明人： John H. Morriss , Greg Liu , Rohit Girotra , Tom Thanh Vo , Richard Roy Newhauser, Jr. , Thomas Jenkins , Joshua Makower
IPC分类号： A61F11/00 , A61M1/00 , A61M3/02
CPC分类号： A61F11/002 , A61F11/006 , A61M1/0031 , A61M1/008 , A61M3/0262 , A61M3/0279 , A61M2210/0675
摘要： A method is disclosed for clearing effusion from an ear. The method may include applying liquid to an ear canal, which is proximal to a perforated tympanic membrane, which is proximal to a middle ear containing effusion, applying an ear device to seal and pressurize the liquid inside the ear canal, the ear device regulating the amount of pressure inside the ear canal, and inducing a Eustachian tube, which is distal to the middle ear, to open, which causes the fluid to displace the effusion into the Eustachian tube.
摘要翻译：公开了一种从耳朵清除渗出物的方法。该方法可以包括将液体施加到耳道，所述耳道接近穿孔鼓膜，所述鼓膜接近含有渗出液的中耳，施加耳朵装置以密封和加压耳道内的液体，耳朵装置调节耳道内的压力量，以及诱导位于中耳远端的咽鼓管打开，导致流体将渗出液置于咽鼓管内。

5. 发明申请

US20170119414A1 FLUID COMMUNICATION FEATURES FOR EUSTACHIAN TUBE DILATION INSTRUMENT 审中-公开
公开(公告)号：US20170119414A1
公开(公告)日：2017-05-04
申请号：US14928114
申请日：2015-10-30
申请人： Acclarent, Inc.
发明人： Randy S. Chan , Siddhi K. Desai , Ketan P. Muni , Hung V. Ha , Andrew Drake
IPC分类号： A61B17/24 , A61B17/12
CPC分类号： A61B17/24 , A61B2017/00336 , A61B2017/00367 , A61B2017/00424 , A61B2017/00787 , A61F11/002 , A61M25/0041 , A61M25/0097 , A61M29/00 , A61M29/02 , A61M2210/0675
摘要： A system for dilating a Eustachian tube (ET) of a patient includes a guide member and a dilation catheter. The guide member includes a bent distal portion that is configured to provide access to an opening in the ET. The dilation catheter is slidable relative to the guide member. The dilation catheter includes a shaft, an expandable element, and an actuator. The expandable element is disposed at the distal portion of the shaft. The actuator includes a grasping portion and an actuating member. The expandable element is configured to transition to an expanded configuration in response to actuation of the actuating member. The grasping portion and actuating member are configured to be grasped in a single hand of an operator to enable the operator to advance the dilation catheter relative to the guide member and to transition the expandable element between expanded and unexpanded configurations with the single hand.

6. 发明申请

US20160302972A1 Nasal Air Flow Device 审中-公开
标题翻译：鼻气流装置
公开(公告)号：US20160302972A1
公开(公告)日：2016-10-20
申请号：US14687669
申请日：2015-04-15
申请人： Exercore LLC
发明人： Kevin Connelly , Derek Lidbom
IPC分类号： A61F11/00 , A61M13/00
CPC分类号： A61F11/00 , A61M13/003 , A61M2205/8206 , A61M2210/0618 , A61M2210/0668 , A61M2210/0675
摘要： An apparatus for equalizing pressure and exercising the Eustachian tubes includes a hand held air source for providing a flow of air into a nostril while the other nostril is shut. Swallowing during the intake of air in the nostril helps to open the Eustachian tubes and routine use on a daily can prevent problems associated with flying, scuba diving, colds and allergies. A simpler and less expensive air pressure limiting device limits the air pressure perceived at the nose by way of a unique air tube configured with simple side openings and screws adjusted when manufactured to preset the maximum air pressure.
摘要翻译：用于均衡压力和行使咽鼓管的装置包括手持空气源，用于在另一个鼻孔关闭时提供空气流入鼻孔。在鼻孔摄入期间吞咽有助于打开咽鼓管，每天常规使用可以防止与飞行，水肺潜水，感冒和过敏有关的问题。一个更简单且更便宜的空气压力限制装置通过独特的空气管限制了在鼻子处感觉到的空气压力，该空气管配置有简单的侧开口和当制造为预设最大气压时调节的螺钉。

7. 发明申请

US20160287055A1 GUIDE CATHETER WITH IMAGE CAPTURE AND LIGHT EMISSION FEATURES 有权
标题翻译：导向导管与图像捕捉和发光特征
公开(公告)号：US20160287055A1
公开(公告)日：2016-10-06
申请号：US14826400
申请日：2015-08-14
申请人： Acclarent, Inc.
发明人： Randy J. Kesten , Ketan P. Muni , James Patrick Garvey, II , Hung V. Ha , Andy Nguyen
IPC分类号： A61B1/00 , A61B1/227 , A61B17/29 , A61B1/05 , A61B1/06
CPC分类号： A61B1/00082 , A61B1/00087 , A61B1/00135 , A61B1/012 , A61B1/018 , A61B1/05 , A61B1/0623 , A61B1/0684 , A61B1/227 , A61B1/233 , A61B17/24 , A61B17/29 , A61B17/3421 , A61B90/361 , A61B2017/00331 , A61B2017/00787 , A61B2017/345 , A61B2090/306 , A61M25/0041 , A61M25/0054 , A61M25/0068 , A61M25/01 , A61M25/0662 , A61M25/10 , A61M29/02 , A61M2025/0046 , A61M2025/0681 , A61M2029/025 , A61M2205/32 , A61M2210/0675 , A61M2210/0681
摘要： A dilation catheter system comprises a guide member, a dilation catheter, and an image sensor. The guide member includes a shaft comprising a distal end and a proximal end. The shaft further defines a longitudinal axis. The dilation catheter is movable relative to the guide catheter member and comprises an expandable dilator. The expandable dilator is sized to fit within one or both of a Eustachian tube or a passageway associated with a paranasal sinus. The image sensor is configured to provide visualization within anatomy of a patient. The image sensor is integral with the guide member.
摘要翻译：扩张导管系统包括引导构件，扩张导管和图像传感器。引导构件包括轴，该轴包括远端和近端。轴还限定纵向轴线。扩张导管可相对于导引导管构件移动并且包括可扩张的扩张器。可扩张扩张器的尺寸设置成适合于咽鼓管或与鼻旁窦相关联的通道中的一个或两个。图像传感器被配置为在患者的解剖结构内提供可视化。图像传感器与引导构件成一体。

8. 发明申请

US20110301569A1 Methods and apparatus for the CVCS 审中-公开
标题翻译： CVCS的方法和装置
公开(公告)号：US20110301569A1
公开(公告)日：2011-12-08
申请号：US13199012
申请日：2011-08-16
申请人： Gordon Wayne Dyer
发明人： Gordon Wayne Dyer
IPC分类号： A61F11/00 , A61M37/00
CPC分类号： A61K9/0043 , A61K9/0073 , A61M15/0098 , A61M16/0866 , A61M2202/0468 , A61M2210/0675
摘要： The present invention provides an indirect method and accompanying apparatus for supplying a high concentration of medicaments, particularly antibiotics, to the nasal sinuses by first loading the medicament into the cerebrospinal venous system (CVCS) via a Valsalva manuever. Because the CVCS is a valveless, three-dimensional closed system, traditional physiological dogma such as veins always draining tissues does not always apply. Instead, because in its closed-system blood can flow in any direction, the blood of the CVCS and any medicaments that it contains will be drawn to any portion of it where there is increased outflow, such as the copious venous-derived sinus fluid drainage present during nasal allergy or nasal infection. Thus, the very nasal congestion that impedes the effectiveness of direct medicament application, such as seen with nasal inhalers or systemic antibiotics, aids in applying the medicament indirectly to the nasal sinuses via the CVCS. Additionally, the present method has the benefit of delivering medicaments that, unlike present treatment regimens, are not limited solely to those medicaments that can be successfully absorbed from the G.I. tract. This means that, in the case of antibiotics, the bacteria infecting this portion of the CVCS will not be as resistant to treatment if they have not had prior exposure to this new line of antibiotics. Finally, if the infection extends to the eardrums, making the Valsalva maneuver painful, or if the patient is simply unusually sensitive, then earplugs to reduce the stress on the eardrums may be worn while the patient performs the Valsalva maneuver.
摘要翻译：本发明提供了一种通过首先通过Valsalva manuever将药物加载到脑脊静脉系统（CVCS）中来向鼻窦供应高浓度药物，特别是抗生素的间接方法和伴随装置。因为CVCS是一种无阀式三维封闭系统，传统的生理教条如静脉总是排出组织并不总是适用。相反，因为在其闭合系统的血液中可以流向任何方向，CVCS的血液及其含有的任何药物将被吸入其中流出物增加的任何部分，例如大量静脉导出的窦液引流鼻过敏或鼻感染时出现。因此，妨碍直接药物应用的有效性的鼻部充血，例如用鼻吸入器或全身抗生素观察，有助于通过CVCS间接地将药物施用于鼻窦。此外，本方法具有递送药物的益处，其与现有的治疗方案不同，不仅仅限于可以从G.I.成功吸收的那些药物。道。这意味着，在抗生素的情况下，感染CVCS的这一部分的细菌如果没有接触过这种新的抗生素系列，就不会像治疗一样耐药。最后，如果感染延伸到耳膜，使Valsalva手术变得痛苦，或者如果患者仅仅是异常敏感的话，那么当患者进行Valsalva手术时，可能会佩戴耳塞以减轻耳膜上的压力。

9. 发明申请

US20090076581A1 IMPLANTATABLE COMPONENT HAVING AN ACCESSIBLE LUMEN AND A DRUG RELEASE CAPSULE FOR INTRODUCTION INTO SAME 有权
标题翻译：具有可接受的乳液的可植入组分和用于引入其的药物释放胶囊
公开(公告)号：US20090076581A1
公开(公告)日：2009-03-19
申请号：US12248889
申请日：2008-10-09
申请人： Peter Gibson
发明人： Peter Gibson
IPC分类号： A61F2/18 , A61N1/04
CPC分类号： A61F11/00 , A61M5/14244 , A61M5/14276 , A61M25/00 , A61M31/002 , A61M2210/0662 , A61M2210/0668 , A61M2210/0675 , A61N1/0541 , A61N1/36032 , A61N1/36036 , H04R25/606
摘要： In one aspect of the invention, a method for delivering drugs from an implantable medical device to an implantee is disclosed, comprising implanting the medical device having a receptacle configured to receive a drug release capsule, the drug release capsule having at least one drug disposed thereon, placing the drug release capsule in the receptacle subsequent to the implanting, and permitting the release of the at least one drug from the drug release capsule to the recipient
摘要翻译：在本发明的一个方面，公开了一种用于将药物从可植入医疗装置输送到植入物的方法，包括植入具有接收药物释放胶囊的容器的医疗装置，所述药物释放胶囊具有至少一种药物，，在植入之后将药物释放胶囊放置在容器中，并允许将至少一种药物从药物释放胶囊释放到接受者

10. 发明授权

US5431636A Device for equalizing pressure in the middle ear 失效
标题翻译：用于平衡中耳压力的装置
公开(公告)号：US5431636A
公开(公告)日：1995-07-11
申请号：US138386
申请日：1993-10-20
申请人： Sven-Erik Stangerup
发明人： Sven-Erik Stangerup
IPC分类号： A61F11/00 , A61M13/00 , A61B5/08
CPC分类号： A61F11/00 , A61M13/003 , A61M2210/0618 , A61M2210/0675
摘要： A device for equalizing the pressure in the middle ear is comprised of a unit having one end that is to be positioned in a nostril and an opposite end that is provided with a rib. A balloon is positioned on the unit adjacent the rib. The unit is provided with a through hole whose smallest cross-sectional area is greater than or equal to 7 mm.sup.2. The elasticity of the balloon is such that a counter pressure of at least 20 mBar is produced upon being blown up.
摘要翻译：用于使中耳中的压力均衡的装置包括具有位于鼻孔中的一端的单元和设置有肋的相对端。气球位于邻近肋骨的单元上。该单元具有最小横截面积大于或等于7mm 2的通孔。气球的弹性使得在吹起时产生至少20mBar的反压力。

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