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1. 发明公开

US20240252762A1 INJECTION MONITORING DEVICE AND SYSTEM 审中-公开
公开(公告)号：US20240252762A1
公开(公告)日：2024-08-01
申请号：US18244874
申请日：2023-09-11
申请人： Sawhney Nisha , Singh Kumar Shiv
发明人： Sawhney Nisha , Singh Kumar Shiv
IPC分类号： A61M5/315 , A61M5/31 , G16H20/17 , G16H40/63
CPC分类号： A61M5/31573 , A61M5/31568 , G16H20/17 , G16H40/63 , A61M2005/3126 , A61M2205/18 , A61M2205/3331 , A61M2205/3584 , A61M2205/502 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/6072
摘要： A syringe use monitoring device that can attach to a syringe and detect the type of medication being loaded and measure the force applied to the plunger and thus monitor subsequent delivery of medication and delivery pressure as a substance is being injected, and at least one display and/or alarm can indicate normal and/or abnormal conditions so that feedback can be employed during the injection process is provided.

2. 发明公开

US20240252756A1 Medical Delivery Devices Having Low Lubricant Syringe Barrels 审中-公开
公开(公告)号：US20240252756A1
公开(公告)日：2024-08-01
申请号：US18441395
申请日：2024-02-14
申请人： W. L. Gore & Associates, Inc.
发明人： Michael C. Berg , Daniel H. Todd , Eric J. Van Voorhees
IPC分类号： A61M5/31 , A61L31/04 , A61L31/14 , A61M5/315
CPC分类号： A61M5/3129 , A61L31/048 , A61L31/146 , A61M5/31505 , A61M5/31513 , A61M5/31573 , A61L2400/06 , A61L2400/10 , A61M2005/3131 , A61M2005/3143
摘要： The present disclosure relates to medical delivery devices that include a barrel having an inner surface, and in at least one embodiment, the inner surface is hydrophilic. The medical delivery device may further include a stopper may having an elastomeric body, one or more fluoropolymer layers, and two or more ribs laminated to the one or more fluoropolymer layers. In some embodiments, the contact angle of the inner surface of the barrel is less than about 58°. Additionally, the stopper includes a sliding surface that is less than about 2.0 mm. The barrel provides inner surface that in combination with the fluoropolymer laminate or fluoropolymer film achieve high levels of air and liquid impermeability while also maintaining an acceptably low break loose force, low average glide force, and low glide force variation. In some embodiments, the compressibility stopper against the barrel is greater than about 7.9%.

3. 发明授权

US10493207B2 Medical delivery devices having low lubricant syringe barrels 有权
公开(公告)号：US10493207B2
公开(公告)日：2019-12-03
申请号：US15905115
申请日：2018-02-26
申请人： W. L. Gore & Associates, Inc.
发明人： Michael C. Berg , Daniel H. Todd , Eric J. Van Voorhees
IPC分类号： A61M5/31 , A61M5/315 , A61L31/14 , A61L31/04
CPC分类号： A61M5/3129 , A61L31/048 , A61L31/146 , A61M5/31505 , A61M5/31513 , A61M5/31573 , A61L2400/06 , A61L2400/10 , A61M2005/3131 , A61M2005/3143 , A61L31/048 , C08L27/18 , A61L31/048 , C08L27/12
摘要： The present disclosure relates to medical delivery devices that include a barrel having an inner surface, and in at least one embodiment, the inner surface is hydrophilic. The medical delivery device may further include a stopper may having an elastomeric body, one or more fluoropolymer layers, and two or more ribs laminated to the one or more fluoropolymer layers. In some embodiments, the contact angle of the inner surface of the barrel is less than about 58°. Additionally, the stopper includes a sliding surface that is less than about 2.0 mm. The barrel provides inner surface that in combination with the fluoropolymer laminate or fluoropolymer film achieve high levels of air and liquid impermeability while also maintaining an acceptably low break loose force, low average glide force, and low glide force variation. In some embodiments, the compressibility stopper against the barrel is greater than about 7.9%.

4. 发明申请

US20190247585A1 SYSTEMS, KITS AND METHODS FOR LOADING AND DELIVERING A SMALL VOLUME DOSE FROM A SYRINGE 审中-公开
公开(公告)号：US20190247585A1
公开(公告)日：2019-08-15
申请号：US16269910
申请日：2019-02-07
申请人： ICON BIOSCIENCE, INC.
发明人： Cathy Ann GERLETT
IPC分类号： A61M5/315 , A61M5/28
CPC分类号： A61M5/31541 , A61M5/28 , A61M5/31525 , A61M5/31573 , A61M5/31578 , A61M5/3159
摘要： A kit is disclosed for accurately loading a small volume dose of a medication within a syringe and for delivering the small volume dose of the medication at a treatment site. The kit generally includes a loading and delivery system in accordance herewith, a syringe, and a medication. The loading and delivery system includes a syringe delivery ring and a syringe loading guide, which may be used for example, to administer a small volume dose of a medication at the end of an ocular surgery.

5. 发明申请

US20180333527A1 DISPLACEMENT SENSING DEVICE AND PERITONEAL DIALYSIS SYSTEM 审中-公开
公开(公告)号：US20180333527A1
公开(公告)日：2018-11-22
申请号：US15871014
申请日：2018-01-14
申请人： Acer Incorporated , BENEPET CO., LTD.
发明人： Chun-Hung Wen , Wei-Chen Lai , Pu-De Ciou , Wen-Pin Chang , Tsung-Hsun Wu , Wen-Shu Lee , Ta-Lun Tan
IPC分类号： A61M1/28 , A61M1/10
CPC分类号： A61M1/282 , A61M1/1037 , A61M1/28 , A61M5/14216 , A61M5/1452 , A61M5/1684 , A61M5/31573 , A61M2005/31588 , A61M2205/3306 , A61M2205/3327 , A61M2205/3334 , A61M2205/3389 , F04B13/00 , F04B17/03 , F04B43/06 , F04B43/12 , F04B2201/0201
摘要： A displacement sensing device is configured for a peritoneal dialysis system. The peritoneal dialysis system includes a housing and a syringe. The syringe is disposed on the housing and has a push rod. The displacement sensing device includes a guide rod, a probing module, and a resistance scale. The guide rod is coupled to the push rod, and the probing module is disposed in the housing and is fixed at the guide rod. The resistance scale is disposed at a side of the probing module. The probing module is configured to contact the resistance scale to obtain a resistance value of the resistance scale and determine a displacement magnitude of the push rod. In addition, a peritoneal dialysis system is also mentioned.

6. 发明申请

US20180200444A1 CARTRIDGE HOLD-UP VOLUME REDUCTION 审中-公开
公开(公告)号：US20180200444A1
公开(公告)日：2018-07-19
申请号：US15875115
申请日：2018-01-19
申请人： Insulet Corporation
发明人： Maureen MCCAFFREY , David NAZZARO , Ian MCLAUGHLIN , Simon KOZIN
IPC分类号： A61M5/28 , A61M5/24 , A61M5/32 , A61M5/34
CPC分类号： A61M5/285 , A61J1/2089 , A61M5/142 , A61M5/2455 , A61M5/2466 , A61M5/31573 , A61M5/3293 , A61M5/34 , A61M2005/31516
摘要： Drug delivery systems with reduced hold-up volumes are provided. The drug delivery systems include a cartridge configured to hold a liquid drug. A cartridge stopper is positioned in a first portion of the cartridge. A needle guide component is positioned within the cartridge stopper. A needle is positioned within a central opening of the needle guide. A plunger is positioned in a second portion of the cartridge. The plunger includes a fluid path pocket facing and aligned with the central opening of the needle guide component. The plunger is driven toward the cartridge stopper to expel the liquid drug from the cartridge through the needle. An end of the needle can be positioned within the fluid path pocket when the plunger is pushed against the cartridge stopper, ensuring that only a small volume of the liquid drug remains in the cartridge when delivery of the liquid drug is completed.

7. 发明申请

US20170296755A1 Method for Assembling a Drive Spring and Drug Delivery Device with a Spring 审中-公开
公开(公告)号：US20170296755A1
公开(公告)日：2017-10-19
申请号：US15517314
申请日：2015-10-09
申请人： Sanofi
发明人： William Marsh , Anthony Paul Morris , Matthew Jones , Samuel Steel
IPC分类号： A61M5/315 , A61M5/20 , A61M5/31
CPC分类号： A61M5/31573 , A61M5/2033 , A61M5/31541 , A61M5/31551 , A61M5/31553 , A61M5/31561 , A61M5/31583 , A61M5/31585 , A61M5/31593 , A61M2005/202 , A61M2005/2026 , A61M2005/2407 , A61M2005/3126 , A61M2205/581 , A61M2205/583 , A61M2205/584 , A61M2207/00
摘要： A method for assembling a drive spring, especially into a drug delivery device includes rotating a component part to which the drive spring is attached in a first direction, followed by a rotation of the component part in the opposite direction and followed by attachment of a rotational stop. Further, the disclosure includes a drug delivery device for selecting and dispensing a number of user variable doses of a medicament, which device comprises a pre-charged drive spring.

8. 发明申请

US20170247444A1 ANTI-TNF ANTIBODIES, COMPOSITIONS, METHODS AND USE FOR THE TREATMENT OR PREVENTION OF TYPE 1 DIABETES 审中-公开
公开(公告)号：US20170247444A1
公开(公告)日：2017-08-31
申请号：US15421473
申请日：2017-02-01
申请人： Janssen Biotech, Inc.
发明人： Joseph Hedrick , Elizabeth C. Hsia , Paul Imm , Jocelyn Leu , Bethany Paxson , Mark Rigby , Songmao Zheng , Ramineh Zoka
IPC分类号： C07K16/24
CPC分类号： C07K16/241 , A61K2039/505 , A61K2039/545 , A61M5/003 , A61M5/31533 , A61M5/31573 , A61M5/31591 , A61P3/10 , A61P29/00 , C07K2317/21 , C07K2317/565
摘要： The present invention relates to compositions and methods utilizing anti-TNF antibodies having a heavy chain (HC) comprising SEQ ID NO:36 and a light chain (LC) comprising SEQ ID NO:37 for use in the treatment or prevention of Type I Diabetes (T1D).

9. 发明申请

US20160158455A1 Assembly for a Drug Delivery Device and Method of Operating the Same 有权
标题翻译：药物输送装置的装配及其操作方法
公开(公告)号：US20160158455A1
公开(公告)日：2016-06-09
申请号：US14905446
申请日：2014-07-17
申请人： SANOFI
发明人： Tom OAKLEY , Matt SCHUMANN , Stuart MILNE
IPC分类号： A61M5/315 , A61M5/31
CPC分类号： A61M5/31541 , A61M5/20 , A61M5/3146 , A61M5/31501 , A61M5/31535 , A61M5/31543 , A61M5/31553 , A61M5/31561 , A61M5/3157 , A61M5/31573 , A61M5/31583 , A61M2005/3126 , A61M2205/581 , A61M2205/586
摘要： An assembly for a drug delivery device (200) is presented which comprises a housing (24) having a proximal end (25) and a distal end (26), a cartridge, a plunger (19) which is movably retained in the cartridge (14) and a piston rod (6). The assembly further comprises a rod displacement feature (33). The assembly is configured such that, in an initial state of the assembly, the piston rod (6) and the rod displacement feature (33) are arranged such that movement of the rod displacement feature (33) from the first position to the second position is transferred to the piston rod (6) such that the piston rod (6) is moved with respect to the cartridge (14) and the assembly is switched from the initial state to a primed state. In the primed state, movement of the rod displacement feature (33) from the first position to the second position is not transferred to the piston rod (6).
摘要翻译：提供了一种用于药物输送装置（200）的组件，其包括具有近端（25）和远端（26）的壳体（24），盒，可移动地保持在药筒中的柱塞（19） 14）和活塞杆（6）。组件还包括杆移位特征（33）。组件被构造成使得在组件的初始状态下，活塞杆（6）和杆移动特征（33）被布置成使得杆移动特征（33）从第一位置移动到第二位置被传递到活塞杆（6），使得活塞杆（6）相对于盒（14）移动并且组件从初始状态切换到初始状态。在起动状态下，杆位移特征（33）从第一位置到第二位置的移动不被传递到活塞杆（6）。

10. 发明授权

US09345835B2 Cartridge stopper for an intradermal delivery system 有权
标题翻译：用于皮内递送系统的塞子塞子
公开(公告)号：US09345835B2
公开(公告)日：2016-05-24
申请号：US12737453
申请日：2009-07-17
申请人： Ying Xu , Robert Banik , Lionel Vedrine
发明人： Ying Xu , Robert Banik , Lionel Vedrine
IPC分类号： A61M5/00 , A61M5/315 , A61M5/24
CPC分类号： A61M5/31511 , A61M5/24 , A61M5/2466 , A61M5/31515 , A61M5/31551 , A61M5/31573 , A61M5/31585 , A61M2005/2407
摘要： A device for delivering a medicament intradermally includes a cartridge (112) having a first end (110) and a second end (114) and defining a volume (111) therebetween. The volume (111) is adapted to contain the medicament. A driving member (121) has a first end (126) and a second end (128). The first end (126) of the driving member (121) is disposed in the cartridge (112) and the second end (128) of the driving member (121) is disposed outside the cartridge (112). A stopper (115) is slidably disposed in the cartridge volume (111). The driving member (121) is releasably disposed in the stopper (115) such that when the driving member (121) is retracted from the cartridge (112) the stopper (115) is disengaged from the driving member (121) and remains in the cartridge volume (111).
摘要翻译：用于皮内递送药物的装置包括具有第一端（110）和第二端（114）并且在其间限定体积（111）的药筒（112）。体积（111）适于容纳药物。驱动构件（121）具有第一端（126）和第二端（128）。驱动构件（121）的第一端（126）设置在盒（112）中，并且驱动构件（121）的第二端（128）设置在盒（112）的外部。止动器（115）可滑动地设置在盒体积（111）中。驱动构件（121）可释放地设置在止动件（115）中，使得当驱动构件（121）从盒（112）缩回时，止动件（115）与驱动构件（121）脱离并保持在盒体积（111）。

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