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1. 发明申请

US20160236232A1 ELECTROSPINNING WITH REDUCED CURRENT OR USING FLUID OF REDUCED CONDUCTIVITY 审中-公开
公开(公告)号：US20160236232A1
公开(公告)日：2016-08-18
申请号：US14991878
申请日：2016-01-08
申请人： Nanostatics Corporation
发明人： Ashley S. Scott , John A. Robertson , Andrew L. Washington
IPC分类号： B05D1/00 , D01D5/00 , D01F1/02 , C09D125/06 , D01F6/22
CPC分类号： B05D1/007 , B05C5/00 , B82Y40/00 , C08L23/04 , C09D125/06 , D01D5/003 , D01F1/02 , D01F6/22 , Y10T428/298
摘要： A method comprises: dissolving an aromatic side chain polymer in a terpene, terpenoid, or aromatic solvent; dissolving an inorganic salt in a polar organic solvent; mixing the salt solution and the polymer solution; and using a predominantly terpene, terpenoid, or aromatic solvent phase of the mixture as electrospinning fluid. The fluid is electrospun from spinning tip(s) onto a target substrate. The inorganic salt and the polar organic solvent are chosen so as not to cause substantial precipitation of the polymer upon mixing with the polymer solution. The terpene, terpenoid, or aromatic solvent can comprises D-limonene, the aromatic side chain polymer can comprise polystyrene, the polar organic solvent can comprise dimethyl formamide, and the inorganic salt can comprise LiCl, AgNO3, CuCl2, or FeCl3. The method can further comprise electrospinning the fluid with the fluid and spinning tips electrically isolated from a voltage source that drives the electrospinning.

2. 发明申请

US20160040121A1 THERMALLY RESPONSIVE CELL CULTURE SURFACES 审中-公开
标题翻译：热应答细胞培养表面
公开(公告)号：US20160040121A1
公开(公告)日：2016-02-11
申请号：US14804105
申请日：2015-07-20
申请人： Innovative Surface Technologies, Inc.
发明人： Tahmina Naqvi , Jie Wen , Patrick Guire
IPC分类号： C12N5/00 , C12M1/24 , C12M1/00 , C12M1/12
CPC分类号： C12N5/0068 , A61L27/16 , A61L27/34 , A61L27/50 , A61L27/54 , A61L29/041 , A61L29/085 , A61L29/14 , A61L29/16 , A61L31/048 , A61L31/10 , A61L31/14 , A61L31/16 , A61L2300/00 , A61L2400/12 , C12M23/08 , C12M23/20 , C12M25/14 , C12N2533/30 , C12N2537/10 , C12N2539/00 , D01D5/0007 , D01F1/10 , D01F6/22 , D01F6/26 , D01F6/625 , D06M15/285 , D06M2400/01 , G01N33/48 , C08L33/26
摘要： A stimuli responsive nanofiber that includes a stimuli responsive polymer, such as a thermally responsive polymer, and a cross-linking agent having at least two latent reactive activatable groups. The nanofiber may also include a biologically active material or a functional polymer. The stimuli responsive nanofiber can be used to modify the surface of a substrate. When the nanofiber includes a thermally responsive polymer, the physical properties of the surface can be controlled by controlling the temperature of the system, thus controlling the ability of the surface to bind to a biologically active material of interest.
摘要翻译：刺激响应性纳米纤维，其包括刺激响应性聚合物，例如热响应性聚合物，以及具有至少两个潜在反应性可活化基团的交联剂。纳米纤维还可以包括生物活性材料或功能性聚合物。刺激性响应性纳米纤维可用于改性基材的表面。当纳米纤维包含热响应性聚合物时，可以通过控制体系的温度来控制表面的物理性能，从而控制表面结合生物活性物质的能力。

3. 发明授权

US09029149B2 Methods, apparatus, and systems for fabrication of polymeric nano- and micro-fibers in aligned configurations 有权
标题翻译：用于在对准构型中制造聚合物纳米和微纤维的方法，装置和系统
公开(公告)号：US09029149B2
公开(公告)日：2015-05-12
申请号：US12512893
申请日：2009-07-30
申请人： Amrinder Singh Nain
发明人： Amrinder Singh Nain
IPC分类号： C12N5/071 , B28B21/52 , B32B5/00 , D01F6/22 , A61L27/38 , B81C99/00 , C12N5/00 , D01D5/04
CPC分类号： C12N5/0075 , A61L27/3804 , A61L27/3895 , B81C99/003 , C12N5/0068 , C12N2513/00 , C12N2533/30 , C12N2533/40 , C12N2533/54 , C12N2537/00 , D01D5/04 , D01F6/22 , D10B2321/121 , D10B2331/041 , Y10T428/269
摘要： Provided herein are apparatus and systems for fabricating highly aligned arrays of polymeric fibers having isodiameters ranging from sub 50 nm to microns with lengths of several millimeters. The approach disclosed herein uses (e.g.) a micropipette to deliver polymeric solution which is collected in the form of aligned fibers on a rotating and linearly translating substrate. The methods deposit polymeric fibers on spherical surfaces and gapped surfaces with precise control, thus heralding new opportunities for a variety of applications employing polymeric fibers. The design workspace for depositing fibers disclosed herein is dependent upon processing parameters of rotational/linear translational speeds and material properties of solution rheologies. Techniques for fabrication of multilayer fiber arrays, for fabrication of cell growth scaffolds and for attachment of particles to the fiber arrays are also disclosed.
摘要翻译：本文提供了用于制造聚合物纤维的高度排列的阵列的装置和系统，其具有范围在几百毫米长度的小于50nm至微米的特征参数。本文公开的方法使用（例如）微量移液管将以对准纤维的形式收集的聚合物溶液输送到旋转和线性平移的基底上。该方法将聚合物纤维沉积在具有精确控制的球形表面和间隙表面上，从而为使用聚合物纤维的各种应用预示了新的机会。本文公开的用于沉积纤维的设计工作区取决于旋转/线性平移速度和溶液流变学的材料性质的处理参数。还公开了用于制造多孔纤维阵列，用于制造细胞生长支架和用于将颗粒附着到纤维阵列的技术。

4. 发明申请

US20130280436A1 ELECTROSPINNING WITH REDUCED CURRENT OR USING FLUID OF REDUCED CONDUCTIVITY 审中-公开
标题翻译：电流降低电流或使用降低电导率的流体
公开(公告)号：US20130280436A1
公开(公告)日：2013-10-24
申请号：US13787724
申请日：2013-03-06
申请人： Nanostatics Corporation
发明人： Ashley S. Scott , John A. Robertson , Andrew L. Washington, JR.
IPC分类号： B05D1/00 , B05C5/00
CPC分类号： B05D1/007 , B05C5/00 , B82Y40/00 , C08L23/04 , C09D125/06 , D01D5/003 , D01F1/02 , D01F6/22 , Y10T428/298
摘要： A method comprises: dissolving an aromatic side chain polymer in a terpene, terpenoid, or aromatic solvent; dissolving an inorganic salt in a polar organic solvent; mixing the salt solution and the polymer solution; and using a predominantly terpene, terpenoid, or aromatic solvent phase of the mixture as electrospinning fluid. The fluid is electrospun from spinning tip(s) onto a target substrate. The inorganic salt and the polar organic solvent are chosen so as not to cause substantial precipitation of the polymer upon mixing with the polymer solution. The terpene, terpenoid, or aromatic solvent can comprises D-limonene, the aromatic side chain polymer can comprise polystyrene, the polar organic solvent can comprise dimethyl formamide, and the inorganic salt can comprise LiCl, AgNO3, CuCl2, or FeCl3. The method can further comprise electrospinning the fluid with the fluid and spinning tips electrically isolated from a voltage source that drives the electrospinning.
摘要翻译：一种方法包括：将芳族侧链聚合物溶解在萜烯，萜类或芳族溶剂中; 将无机盐溶解在极性有机溶剂中; 混合盐溶液和聚合物溶液; 并且使用主要是萜烯，萜类或芳族溶剂相的混合物作为静电纺丝液。将流体从纺丝尖端电纺到目标基底上。选择无机盐和极性有机溶剂，以便在与聚合物溶液混合时不引起聚合物的显着沉淀。萜烯，萜类或芳族溶剂可以包含D-柠檬烯，芳族侧链聚合物可以包含聚苯乙烯，极性有机溶剂可以包括二甲基甲酰胺，无机盐可以包括LiCl，AgNO 3，CuCl 2或FeCl 3。该方法可以进一步包括将流体和纺丝尖端与驱动静电纺丝的电压源电隔离的静电纺丝。

5. 发明申请

US20120040462A1 NANOFIBERS, NANOFILMS AND METHODS OF MAKING/USING THEREOF 审中-公开
标题翻译： NANOFIBERS，NANOFILERS及其制造/使用方法
公开(公告)号：US20120040462A1
公开(公告)日：2012-02-16
申请号：US13282048
申请日：2011-10-26
申请人： Adra S. Baca , Marie D. Bryhan , Frederick E. Noll , Odessa N. Petzold , Michael W. Price , Wageesha Senaratne , Wanda J. Walczak
发明人： Adra S. Baca , Marie D. Bryhan , Frederick E. Noll , Odessa N. Petzold , Michael W. Price , Wageesha Senaratne , Wanda J. Walczak
IPC分类号： C12M3/00
CPC分类号： D01D5/003 , A61L27/06 , A61L27/16 , A61L2400/12 , B82Y5/00 , C12N5/0075 , C12N2533/30 , D01F1/10 , D01F6/14 , D01F6/22 , C08L25/06
摘要： Described herein are compositions for making nanofibers and nanofilms composed of metal oxides, organic polymers, or combinations thereof. Also described herein are methods for making nanofibers and nanofilms where the fibers are formed from a solution having more than one solvent, where the solvents are immiscible. Nanofibers and nanofilms composed of metal oxides, organic polymers or combinations thereof are described. Finally, methods for using the nanofibers and nanofilms are described.
摘要翻译：本文描述了用于制备由金属氧化物，有机聚合物或其组合组成的纳米纤维和纳米薄膜的组合物。本文还描述了制备纳米纤维和纳米薄膜的方法，其中纤维由具有多于一种溶剂的溶液形成，其中溶剂是不混溶的。描述了由金属氧化物，有机聚合物或其组合构成的纳米纤维和纳米薄膜。最后，描述了使用纳米纤维和纳米薄膜的方法。

6. 发明申请

US20090076530A1 SCAFFOLD 审中-公开
标题翻译：脚手架
公开(公告)号：US20090076530A1
公开(公告)日：2009-03-19
申请号：US12281923
申请日：2007-03-05
申请人： Chiaki Fukutomi , Hiroaki Kaneko , Eiichi Kitazono , Mika Kayashima , Miyuki Nakayama
发明人： Chiaki Fukutomi , Hiroaki Kaneko , Eiichi Kitazono , Mika Kayashima , Miyuki Nakayama
IPC分类号： A61B17/08 , A61B19/00
CPC分类号： C12N5/0068 , A61L27/14 , A61L27/18 , A61L27/50 , A61L27/56 , A61L27/58 , C12M25/14 , C12N2533/30 , C12N2533/40 , D01D5/0007 , D01F6/04 , D01F6/22 , D01F6/66 , D04H3/07 , C08L67/04
摘要： To provide a scaffold having excellent mechanical strength and cell growth capability and is suitable for use as a cell culture medium or a prosthetic material.The present invention relates to a scaffold composed of an assembly of fibers and having a 3-D structure consisting of two end faces and a side face, wherein (1) the fibers are aligned in a plane direction; (2) the fibers have a diameter of 0.05 to 50 μm; (3) the fibers are essentially composed of a biocompatible polymer; and (4) the scaffold has an apparent density of 95 to 350 kg/m3.
摘要翻译：提供具有优异的机械强度和细胞生长能力的支架，并且适合用作细胞培养基或假体材料。本发明涉及一种由纤维组合体构成的具有由两个端面和侧面组成的3-D结构的支架，其中（1）纤维沿平面方向排列; （2）纤维的直径为0.05〜50μm; （3）纤维基本上由生物相容性聚合物组成; 和（4）支架具有95至350kg / m 3的表观密度。

7. 发明授权

US5156797A Nonwoven fabrics 失效
标题翻译：无纺布
公开(公告)号：US5156797A
公开(公告)日：1992-10-20
申请号：US775690
申请日：1991-10-10
申请人： Komei Yamasaki , Keisuke Funaki
发明人： Komei Yamasaki , Keisuke Funaki
IPC分类号： D01F6/22 , D04H1/42
CPC分类号： D01F6/22 , D04H1/4291
摘要： Nonwoven fabrics are disclosed, which are produced by molding a material containing as a main component a styrene-based polymer with mainly syndiotactic configuration, in such a manner that a difference between the absolute value of heat of fusion .vertline..DELTA.Hf.vertline. and the absolute value of crystallizing enthalpy on heating .vertline..DELTA.Htcc.vertline. of the molded polymer is at least 1 cal/g. These nonwoven fabrics are excellent in heat-resistant and chemical-resistant characteristics, and are suitable for use as medical fabrics, industrial filters, battery separators and so forth.
摘要翻译：公开了以下方式制造的无纺布，其以包含主要成分的主要成分为主要间同立构构型的苯乙烯类聚合物，以熔融热绝对值| DELTA Hf|和绝对值在加热时结晶焓|模塑聚合物的DELTA Htcc|为至少1cal / g。这些无纺布耐热耐化学特性优异，适用于医用织物，工业过滤器，电池隔板等。

8. 发明授权

US5145631A Melt blowing process for producing microfibers of syndiotactic vinyl aromatic polymers 失效
标题翻译：用于生产间同立构乙烯基芳族聚合物的微纤维的熔融吹制方法
公开(公告)号：US5145631A
公开(公告)日：1992-09-08
申请号：US688647
申请日：1991-04-19
申请人： Zdravko P. Jezic
发明人： Zdravko P. Jezic
IPC分类号： D01D5/098 , D01F6/22 , D04H1/56
CPC分类号： D01F6/22 , D01D5/0985 , D04H1/56
摘要： A melt-blowing process for producing a fiber preferably a microfiber of a syndiotactic vinyl aromatic polymer, which comprises supplying a vinyl aromatic polymer having a high degree of syndiotacticity in a molten form from at least one orifice of a nozzle into a gas stream which attenuates the molten polymer into microfibers. Such microfibers are particularly useful in the field of high temperature filtration, coalescing and insulation.
摘要翻译：一种用于制造纤维的熔喷方法，优选为间同立构乙烯基芳族聚合物的超细纤维，其包括将熔融形式的高度间同立构规整的乙烯基芳族聚合物从喷嘴的至少一个喷嘴供入到气流中，将熔融的聚合物变成微纤维。这种微纤维在高温过滤，聚结和绝缘领域特别有用。

9. 发明授权

US3354114A Polystyrene fiber-finely divided silica thickening agent, and organic liquid materials thickened therewith 失效
标题翻译：聚苯乙烯纤维细分二氧化硅增稠剂，以及有机液体材料
公开(公告)号：US3354114A
公开(公告)日：1967-11-21
申请号：US34913464
申请日：1964-03-03
申请人： GRACE W R & CO
发明人： FRANCIS DOYLE CARROLL
IPC分类号： B01J19/06 , C08J3/12 , C08K3/36 , C08L63/00 , C08L67/00 , C09D7/00 , C10L7/02 , D01D5/42 , D01F6/20
CPC分类号： D01F6/22 , B01J19/06 , C08J3/12 , C08J2325/06 , C08K3/36 , C08L25/06 , C08L63/00 , C08L67/00 , C08L2205/16 , C09D7/44 , C10L7/02 , D01D5/423 , D01F1/10 , C08L2666/04 , C08L2666/06
摘要： Composition comprising a fuel and a thickener which consists of fibres derived from oriented expanded polystyrene having their major dimension less than 50 microns and a length to diameter ratio greater than 10 to 1, optionally combined with 10 to 90% by weight of silica of particle size less than 10 microns. In an example 100 gms. of benzene is mixed with 3 gms. of polystyrene/silica thickener followed by a further 4 grams of the thickener.ALSO:Polystyrene fibres suitable for use as thickening agents are derived from oriented, expanded polystyrene and have their major dimension less than 50 microns and a length to diameter ratio greater than 10 to 1. The preferred values are a major dimension less than 10 microns and a length to diameter ratio greater than 500 to 1. The thickening agents may also be compositions which consist of an intimate mixture of fine-sized silica of particle size less than 10 microns and the polystyrene fibres. Preferably the composition contains 10-90% by weight of polystyrene fibres and 90-10% by weight of silica. The polystyrene fibres may be prepared by introducing oriented expanded polystyrene into the grinding chamber of a fluid energy mill, comminuting it therein and collecting the fine fibres produced. The polystyrene fibre-silica composition may be prepared by introducing oriented expanded polystyrene and silica aerogel simultaneously into the grinding chamber and comminuting them together. Compositions comprising liquid unsaturated polyesters or liquid polyepoxides and 0.1 to 5.0% of their weight of thickener are also claimed.

10. 发明授权

US2900220A Process for melt spinning and orienting polystyrene filaments 失效
标题翻译：熔融纺丝和取向聚苯乙烯丝的方法
公开(公告)号：US2900220A
公开(公告)日：1959-08-18
申请号：US40289854
申请日：1954-01-08
申请人： GILBERT SHAW
发明人： GILBERT SHAW
IPC分类号： D01F6/20 , D02J1/22
CPC分类号： D02J1/225 , D01F6/22 , D02J1/224 , Y10S8/09 , Y10S8/10

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