会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 5. 发明授权
    • Devices and methods for detection of microorganisms via MIE scattering
    • 通过MIE散射检测微生物的装置和方法
    • US09562855B1
    • 2017-02-07
    • US13458650
    • 2012-04-27
    • Jeong-Yeol YoonDavid Jinsoo You
    • Jeong-Yeol YoonDavid Jinsoo You
    • G01N21/47G01N33/58B01L3/00G01N33/569
    • G01N21/47B01L3/502B01L2300/0816G01N33/54313G01N33/54373G01N33/569G01N33/56911G01N33/585G01N2021/4704G01N2021/4707G01N2021/4711
    • Microfluidic methods and systems for detecting levels of microorganisms via Mie forward light scattering. The systems and methods of the present invention can be customized so as to optionally maximize scatter from the particle immunoagglutination and minimize that of the sample matrix, e.g., via selection of parameters particle diameter d, wavelength of incident λ, and/or scatter angle θ. Methods feature providing beads conjugated with an antibody specific for the microorganism, mixing beads with a sample to form a first mixture; providing a control mixture; irradiating the mixtures with incident light; detecting forward light scattering scattered by the first mixture at a first angle with respect to the incident light and forward scattered light scattered by the control the same first angle with respect to the incident light; determining I and I0 from the light scattering; comparing I with I0; and determining a level of the microorganism.
    • 用于通过Mie前向光散射检测微生物水平的微流控方法和系统。 可以定制本发明的系统和方法,以便可选地使颗粒免疫凝集的散射最大化,并使样品基质的散射最小化,例如通过选择参数粒径d,入射λ的波长和/或散射角θ 。 方法特征在于提供与微生物特异性抗体缀合的珠粒,将珠子与样品混合以形成第一混合物; 提供控制混合物; 用入射光照射混合物; 检测由第一混合物散射的相对于入射光的第一角度的向前光散射,并且通过控制散射的向前散射的光相对于入射光具有相同的第一角度; 从光散射确定I和I0; 将I与I0进行比较 并确定微生物的水平。
    • 8. 发明申请
    • FLOW TYPE SINGLE-PARTICLE SPECTROMETER
    • 流式单颗粒光谱仪
    • US20150300881A1
    • 2015-10-22
    • US14440899
    • 2012-11-08
    • HITACHI, LTD.
    • Kei TAKENAKAShigenori TOGASHI
    • G01J3/44G01N15/14G01N21/64
    • G01J3/4406G01J3/4412G01N15/1434G01N21/47G01N21/645G01N2021/4707G01N2021/6417G01N2021/6493G01N2201/06113
    • A flow type single-particle spectrometer includes a sample container which holds a sample liquid containing a particle to be inspected; a detection channel which is a flow path for optically detecting the particle to be inspected; a waste liquid container which stores the sample liquid flowing out through the detection channel; a liquid feed member; a white light source which emits white light; an excitation light dispersion element which spatially disperses the white light into wavelength components; an excitation light collecting element which collects light; a fluorescence light collecting element which collects fluorescence light and side scattered light; a fluorescence light dispersion element which spatially disperses the fluorescence light into wavelength components; a dispersed light collecting element which collects the fluorescence light dispersed by the fluorescence light dispersion element; and a multi-channel light detector which detects intensity of light for each wavelength.
    • 流式单粒子光谱仪包括容纳待检查颗粒的样品液的样品容器; 检测通道,其是用于光学检测待检查的颗粒的流路; 废液容器,其存储通过检测通道流出的样品液体; 液体进料构件; 发出白光的白光源; 将白光空间分散成波长成分的激发光分散元件; 收集光的激发光收集元件; 收集荧光和侧向散射光的荧光聚光元件; 荧光光分散元件,其将荧光光空间分散成波长成分; 收集由荧光分散元件分散的荧光的散射光收集元件; 以及检测各波长的光强度的多通道光检测器。