专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US11180441B2 Method for preparing substituted 4-aminoindane derivatives 有权
公开(公告)号：US11180441B2
公开(公告)日：2021-11-23
申请号：US16624183
申请日：2018-06-20
申请人： Bayer Aktiengesellschaft
发明人： Sergii Pazenok , Christoph Saemann , Yuriy Shermolovich
IPC分类号： C07C209/54 , C07C211/60
摘要： The present invention relates to a method for preparing substituted 4-aminoindane derivatives of the general formula (I) by rearrangement of compounds of the formula (II) in HF, wherein R1, R2, R3, R4, and R5 have the definitions as specified in the description.

2. 发明申请

US20200087244A1 METHOD OF PRODUCING DIAMINES AND POLYAMINES OF THE DIPHENYLMETHANE SERIES AT DIFFERENT PRODUCTION CAPACITIES 审中-公开
公开(公告)号：US20200087244A1
公开(公告)日：2020-03-19
申请号：US16470300
申请日：2017-12-18
申请人： COVESTRO DEUTSCHLAND AG
发明人： Thomas KNAUF , Stefan WERSHOFEN , Klaus-Gerd GRUNER , Volker HARTJES
IPC分类号： C07C209/78 , C07C209/54
摘要： The invention relates to a method for producing diamines and polyamines of the diphenylmethane series, by condensing aniline and formaldehyde followed by an acid-catalysed rearrangement at different production capacities. By adapting the temperatures in the acid-catalysed rearrangement step, the rearrangement reaction can be fully completed despite the change in dwell time inevitably associated with changed production capacity, with no undesired changes occurring in the product composition.

3. 发明授权

US10239984B2 Process for the production of di- and polyamines of the diphenylmethane series 有权
公开(公告)号：US10239984B2
公开(公告)日：2019-03-26
申请号：US15323999
申请日：2015-07-02
申请人： Covestro Deutschland AG
发明人： Jürgen Arras , Stefan Wershofen , Javier Pérez-Ramirez , Tobias Caesar Keller
IPC分类号： C08G12/00 , C07C209/78 , C08G12/08 , C07C209/54 , B01J29/08 , B01J29/70 , B01J29/18 , B01J29/00
摘要： The invention relates to a production process for polyamines through condensation of aromatic amines with formaldehyde employing at least one solid zeolite catalyst partially or fully ion-exchanged to the protonic form which has been A) alkaline-treated, wherein the alkaline treatment is in case of BEA zeolites carried out in the presence of a pore-directing agent and in case of zeolites other than BEA zeolites in the presence or absence of a pore-directing agent, or B) acid-treated without any alkaline treatment preceding or following said acid treatment, wherein the acid treatment is effected with an organic acid with chelating function.

4. 发明申请

US20130225864A1 TRANSAMINATION OF NITROGEN-CONTAINING COMPOUNDS TO HIGH MOLECULAR WEIGHT POLYALKYLENEAMINES 有权
标题翻译：含氮化合物向高分子量聚氨基甲酸铵的分解
公开(公告)号：US20130225864A1
公开(公告)日：2013-08-29
申请号：US13884477
申请日：2011-10-20
申请人： Stephen W. King
发明人： Stephen W. King
IPC分类号： C07C209/54
CPC分类号： C07C209/54 , C07C209/64 , C07C211/14
摘要： A process for preparing high molecular weight acyclic polyamines comprising providing a reaction mixture that includes at least a first component comprising a first organic, nitrogen-containing compound that contains at least two non-tertiary amine groups separated from one another by a ternary or higher carbon atom spacing that can be transaminated in the presence of a hydrogenation/dehydrogenation catalyst to form a mixture of higher molecular weight, acyclic polyamines while minimizing the formation of cyclic polyamines.
摘要翻译：一种制备高分子量无环多胺的方法，包括提供反应混合物，该反应混合物包括至少第一组分，其包含第一有机含氮化合物，其含有通过三元或更高碳彼此分离的至少两个非叔胺基团原子间隔可以在氢化/脱氢催化剂存在下进行转氨以形成较高分子量的无环多胺的混合物，同时最小化环状多胺的形成。

5. 发明授权

US5208376A Process for the continuous preparation of 3,3'-dichloro-benzidine dihydrochloride 失效
标题翻译：连续制备3,3'-二氯苯胺二氯化物的方法
公开(公告)号：US5208376A
公开(公告)日：1993-05-04
申请号：US856063
申请日：1992-06-08
申请人： Kurt Habig , Konrad Baessler , Klaus Warning
发明人： Kurt Habig , Konrad Baessler , Klaus Warning
IPC分类号： C07C209/42 , C07C209/54 , C07C211/52
CPC分类号： C07C209/54
摘要： A process for the continuous preparation of 3,3'-dichlorobenzidine dihydrochloride from 2,2'-dichlorohydrazobenzene by treatment with aqueous sulfuric acid, which comprises treating the 2,2'-dichlorohydrazobenzene, dissolved in a water-immiscible aromatic solvent, continuously at temperatures of from about 20.degree. to about 50.degree. C. in the presence of an alkali metal salt of an alkyl (C.sub.8 -C.sub.23)polyglycol ether sulfate, with such an amount of from about 50 to about 80 % strength aqueous sulfuric acid that the suspension formed remains conveyable, subsequently diluting the suspension emerging from the reaction zone with water, again continuously, and subsequently heating the suspension to a temperature of from about 90.degree. to about 95.degree. C. until a solution is obtained, separating off the aromatic solvent from the hot, sulfuric acid aqueous phase, and precipitating the 3,3'-dichlorobenzidine dihydrochloride by adding hydrochloric acid to the sulfuric acid solution which remains and filtering off this product.
摘要翻译： PCT No.PCT / EP90 / 01844 Sec。 371日期：1992年6月8日 102（e）日期1992年6月8日PCT 1990年11月3日PCT PCT。第WO91 / 07377号公报日本1991年5月30日。一种通过用硫酸水溶液连续制备3,3'-二氯联苯胺二盐酸盐的方法，该方法包括处理溶于水中的2,2'-二氯代苯，不饱和的芳族溶剂，在约20至约50℃的温度下，在烷基（C 8 -C 23）聚乙二醇醚硫酸盐的碱金属盐存在下，其量为约50至约80％形成的悬浮液的强度硫酸水溶液仍然是可输送的，随后再次用水稀释从反应区出来的悬浮液，随后将悬浮液加热到约90℃至约95℃的温度，直至获得溶液，从热硫酸水相中分离芳族溶剂，并通过向硫酸溶液中加入盐酸沉淀出3,3'-二氯联苯胺二盐酸盐，其中r 发出并过滤掉本产品。

6. 发明授权

US4039580A Process for preparing di(aminophenyl)methanes 失效
标题翻译：制备二（氨基苯基）甲烷的方法
公开(公告)号：US4039580A
公开(公告)日：1977-08-02
申请号：US598794
申请日：1975-07-24
申请人： Floro F. Frulla , Adnan A. R. Sayigh , Henri Ulrich , Peter J. Whitman
发明人： Floro F. Frulla , Adnan A. R. Sayigh , Henri Ulrich , Peter J. Whitman
IPC分类号： C08G12/00 , B01J21/00 , C07B61/00 , C07C67/00 , C07C209/00 , C07C209/54 , C07C209/60 , C07C209/78 , C07C211/50 , C07C211/53 , C07C241/00 , C07C265/14 , C08G12/08 , C08G18/76 , C07C85/08
CPC分类号： C08G18/7664
摘要： A process is described for the preparation of polymethylene polyphenyl polyamines containing from 40 to 60 percent by weight of diamine and also containing markedly less high molecular weight polyamines than products hitherto available. Phosgenation of the polyamines gives the corresponding mixture of polymethylene polyphenyl polyisocyanates of markedly lower viscosity and lighter color than products hitherto available, and yielding polymer foams which are substantially white in color.The process comprises condensing aniline and formaldehyde (molar ratio 4-10:1) in the absence of catalyst, separating water from the resulting aminal mixture, contacting the aminals at 20.degree. C to 60.degree. C with a solid catalyst (diatomaceous earths, clays, zeolites) until formation of benzylamines is substantially complete, distilling aniline from the resulting benzylamines under reduced pressure and below 150.degree. C until the aniline content is 3 to 22 percent by weight, and contacting the resulting product with a solid catalyst (diatomaceous earths, clays, zeolites) at 100.degree. C to 190.degree. C until conversion to polymethylene polyphenyl polyamines is complete.
摘要翻译：描述了一种制备含有40至60重量％二胺的聚亚甲基多苯基多胺的方法，并且与目前可获得的产品相比，含有显着较少的高分子量多胺。多胺的光气化产生与目前可获得的产品相比显着低粘度和较浅颜色的聚亚甲基多苯基多异氰酸酯的相应混合物，并产生基本上为白色的聚合物泡沫。

7. 发明授权

US3624126A {66 {11 , {60 -adamantane acetic acid 失效
标题翻译： {66 {11，{60 -ADAMANTANE ACETIC ACID
公开(公告)号：US3624126A
公开(公告)日：1971-11-30
申请号：US3624126D
申请日：1970-05-04
申请人： SQUIBB & SONS INC
发明人： NARAYANAN VENKATACHALA L
IPC分类号： B01J19/12 , C07C53/138 , C07C57/28 , C07C67/00 , C07C209/00 , C07C209/50 , C07C209/54 , C07C211/19 , C07D209/58 , C07C61/28 , C07C69/74
CPC分类号： C07D209/58 , C07C53/138 , C07C57/28
摘要： 1-Azacyclopentano(1,2-a)adamantane compounds and derivatives thereof which have antiviral and anti-inflammatory properties and which are useful cardiovascular agents may be prepared starting from 2-adamantanones or substituted 2-adamantanones and proceeding through a series of intermediate compounds to the corresponding 1-azacyclopentano(1,2-a)-adamantanes. Derivatives may be obtained by reacting the latter with an alkyl or alkenyl halide, haloalkylamine or a haloalkyl substituted amine, a haloalkylcarboxylic acid, an aralkyl halide of up to 10 carbon atoms, or a haloalkyladamantylamine or haloalkyl substituted adamantylamine. The 2-adamantane alkylamine intermediates for the 1-azacyclopentano-(1,2-a)adamantane compounds also have antiviral and anti-inflammatory properties and are useful cardiovascular agents.

8. 发明授权

US1718373A Production of benzidine and derivatives 失效
公开(公告)号：US1718373A
公开(公告)日：1929-06-25
申请号：US39088620
申请日：1920-06-22
申请人： NAT ANILINE & CHEM CO INC
发明人： NELSON RALPH A
IPC分类号： C07C209/54
CPC分类号： C07C209/54

9. 发明授权

US09000217B2 Transamination of nitrogen-containing compounds to high molecular weight polyalkyleneamines 有权
标题翻译：含氮化合物转化成高分子量聚亚烷基胺
公开(公告)号：US09000217B2
公开(公告)日：2015-04-07
申请号：US13884477
申请日：2011-10-20
申请人： Stephen W. King
发明人： Stephen W. King
IPC分类号： C07C209/60 , C07C209/54 , C07C209/64
CPC分类号： C07C209/54 , C07C209/64 , C07C211/14
摘要： A process for preparing high molecular weight acyclic polyamines comprising providing a reaction mixture that includes at least a first component comprising a first organic, nitrogen-containing compound that contains at least two non-tertiary amine groups separated from one another by a ternary or higher carbon atom spacing that can be transaminated in the presence of a hydrogenation/dehydrogenation catalyst to form a mixture of higher molecular weight, acyclic polyamines while minimizing the formation of cyclic polyamines.
摘要翻译：一种制备高分子量无环多胺的方法，包括提供反应混合物，该反应混合物包括至少第一组分，其包含第一有机含氮化合物，其含有通过三元或更高碳彼此分离的至少两个非叔胺基团原子间隔可以在氢化/脱氢催化剂存在下进行转氨以形成较高分子量的无环多胺的混合物，同时最小化环状多胺的形成。

10. 发明申请

US20110190520A1 Process for the preparation of cyclopropyl carboxylic acid esters and derivatives 有权
标题翻译：制备环丙基羧酸酯和衍生物的方法
公开(公告)号：US20110190520A1
公开(公告)日：2011-08-04
申请号：US12929687
申请日：2011-02-08
申请人： Adrian Clark , Elfyn Jones , Ulf Larsson , Anna Minidis
发明人： Adrian Clark , Elfyn Jones , Ulf Larsson , Anna Minidis
IPC分类号： C07C247/22 , C07C67/347 , C07C51/09 , C07C51/60 , C07C209/54 , C07C51/00 , C07C67/52 , C07C67/48 , C07C69/75 , C07C69/653 , C07C57/60 , C07C61/39 , C07C53/50 , C07C211/40
CPC分类号： C07C61/40 , C07B2200/07 , C07C51/09 , C07C51/38 , C07C51/60 , C07C57/60 , C07C57/66 , C07C67/347 , C07C69/753 , C07C211/40 , C07C247/22 , C07C2601/02 , C07C2601/14 , C07D487/04
摘要： The invention relates to a novel process for the preparation of certain cyclopropyl carboxylic acid esters and other cyclopropyl carboxylic acid derivatives; a novel process for the preparation of dimethylsulfoxonium methylide and dimethylsulfonium methylide; to the use of certain cyclopropyl carboxylic acid esters in a process for the preparation of intermediates that can be used in the synthesis of pharmaceutically active entities; and to certain intermediates provided by these processes.
摘要翻译：本发明涉及制备某些环丙基羧酸酯和其它环丙基羧酸衍生物的新方法; 一种制备二甲基锍甲基化物和二甲基锍甲基化物的新方法; 涉及在可用于合成药物活性物质的中间体的制备方法中使用某些环丙基羧酸酯; 以及由这些方法提供的某些中间体。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式