专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US10408820B2 Compounds for modulating integrin CD11B/CD18 有权
公开(公告)号：US10408820B2
公开(公告)日：2019-09-10
申请号：US14311069
申请日：2014-06-20
申请人： The General Hospital Corporation
发明人： Vineet Gupta , M. Amin Arnaout
IPC分类号： G01N33/50 , C07C233/81 , C07C251/20 , C07C311/39 , C07D213/85 , C07D239/48 , C07D249/10 , C07D263/46 , C07D265/34 , C07D277/14 , C07D277/36 , C07D277/42 , C07D277/54 , C07D277/72 , C07D311/16 , C07D333/22 , C07D333/68 , C07D417/06 , C07D417/12 , C07D417/14 , C07D471/04 , C07D471/06 , C07D498/04 , C07D513/18
摘要： The application describes an assay for the identification of small molecule modulators of integrin CD11b/CD18 and small molecules capable of modulating activity of this receptor. Such compounds may be used in certain embodiments for treating a disease or condition selected from inflammation, immune-related disorders, cancer, ischemia-reperfusion injury, stroke, neointimal thickening associated with vascular injury, bullous pemphigoid, neonatal obstructive nephropathy, and cardiovascular disease, or in other embodiments for the treatment of a disease or condition selected from immune deficiency, acquired immune deficiency syndrome (AIDS), myeloperoxidase deficiency, Wiskott-Aldrich syndrome, chronic granulomatous disease, hyper-IgM syndromes, leukocyte adhesion deficiency, Chediak-Higashi syndrome, and severe combined immunodeficiency.

2. 发明授权

US10294440B2 Catalytic system for preparation of high branched alkane from olefins 有权
公开(公告)号：US10294440B2
公开(公告)日：2019-05-21
申请号：US15078830
申请日：2016-03-23
申请人： Shanghai Chemrun Co., Ltd.
发明人： Yong Tang , Wenjie Tao , Xiuli Sun , Junfang Li , Zheng Wang
IPC分类号： C10M105/04 , B01J31/18 , C07C323/45 , C07C251/08 , C07C251/20 , C10G45/48 , C10G45/52 , C10G50/00 , C10G69/12 , C08F10/00 , C07F15/04 , B01J31/22 , C07C251/24 , C08F8/04 , C10M177/00 , C10M107/10 , C08F110/02 , C08F110/08 , C10G50/02
摘要： The present invention discloses a catalytic system for preparing highly branched alkane from olefin, which contains novel nickel or palladium complexes. In the presence of the catalytic system, highly branched oily alkane mixture can be efficiently obtained from olefins (such as ethylene) under mild conditions. The alkane mixture has a low bromine number, and can be used as a processing aid(s) and lubricant base oil with high-performance. Provides also was a method for preparing the catalyst and a method for preparing an oily olefin polymer.

3. 发明申请

US20140221473A1 Compositions, Methods of Use, and Methods of Treatment 有权
标题翻译：组合物，使用方法和治疗方法
公开(公告)号：US20140221473A1
公开(公告)日：2014-08-07
申请号：US14128310
申请日：2012-06-29
申请人： Jahanshah Amin , Kirpal S. Bisht , Meghanath Gali
发明人： Jahanshah Amin , Kirpal S. Bisht , Meghanath Gali
IPC分类号： C07C215/44 , C07C217/52 , C07C211/40 , C07C251/44 , C07C251/20 , C07C323/30 , C07D317/72
CPC分类号： C07C215/44 , C07C211/40 , C07C217/52 , C07C251/20 , C07C251/44 , C07C323/30 , C07C325/02 , C07C2601/14 , C07D317/72
摘要： Embodiments of the present disclosure provide compositions including ketamine analogues, salts, and disalts, pharmaceutical compositions including ketamine analogues, salts, or disalts, methods of treatment of a condition or disease, methods of treatment using compositions or pharmaceutical compositions, and the like.
摘要翻译：本公开的实施方案提供了包含氯胺酮类似物，盐和糖的组合物，包括氯胺酮类似物，盐或糖的药物组合物，治疗病症或疾病的方法，使用组合物或药物组合物的治疗方法等。

4. 发明授权

US07482484B2 Carboxylic acids and derivatives for the treatment of and preventing diabetes and dyslipidaemia 有权
标题翻译：用于治疗和预防糖尿病和血脂异常的羧酸和衍生物
公开(公告)号：US07482484B2
公开(公告)日：2009-01-27
申请号：US10542028
申请日：2003-12-16
申请人： Nathalie Adje , Michel Brunet , Didier Roche , Jean-Jacques Zeiller , Stéphane Yvon , Valérie Guyard-Dangremont , Francis Contard , Daniel Guerrier , Gérard Ferrand , Yves Bonhomme
发明人： Nathalie Adje , Michel Brunet , Didier Roche , Jean-Jacques Zeiller , Stéphane Yvon , Valérie Guyard-Dangremont , Francis Contard , Daniel Guerrier , Gérard Ferrand , Yves Bonhomme
IPC分类号： C07C62/00 , C07C229/40 , C07C251/20
CPC分类号： C07C323/56 , C07C45/46 , C07C45/673 , C07C45/68 , C07C49/747 , C07C49/755 , C07C59/72 , C07C59/90 , C07C65/40 , C07C67/30 , C07C67/31 , C07C69/712 , C07C69/736 , C07C69/76 , C07C205/45 , C07C211/60 , C07C229/18 , C07C233/33 , C07C251/44 , C07C255/40 , C07C309/65 , C07C317/44 , C07C323/22 , C07C323/52 , C07C2602/08 , C07C2602/10 , C07C2602/42 , C07C47/575
摘要： Disclosed are Compounds of formula I And methods of use thereof for the treatment of dyslipidaemia, atherosclerosis and diabetes.
摘要翻译：公开了式I的化合物及其用于治疗血脂异常，动脉粥样硬化和糖尿病的方法。

5. 发明申请

US20050170092A1 Alkaline earth metal complexes and their use 失效
标题翻译：碱土金属络合物及其用途
公开(公告)号：US20050170092A1
公开(公告)日：2005-08-04
申请号：US11022674
申请日：2004-12-28
申请人： Federica Benvenuti , Dominique Jan
发明人： Federica Benvenuti , Dominique Jan
IPC分类号： C07C251/08 , C07C251/20 , C07F3/00 , C23C16/40 , H01L21/316 , C23C16/06 , C07F3/04
CPC分类号： C07C251/20 , C07C251/08
摘要： Chelate complexes of calcium, strontium and barium formed with ligands that are beta-ketiminate compounds having a scorpion tail; intermediate compounds useful in producing the aforementioned complexes; a method for producing such complexes, and the use of such complexes for depositing layers containing calcium, barium or strontium.
摘要翻译：由具有蝎尾的β-酮亚胺化合物的配体形成的钙，锶和钡的螯合络合物; 可用于制备上述络合物的中间体化合物; 制造这种络合物的方法，以及这种配合物用于沉积含有钙，钡或锶的层的用途。

6. 发明授权

US06897275B2 Catalysts for olefin polymerization 失效
公开(公告)号：US06897275B2
公开(公告)日：2005-05-24
申请号：US09871099
申请日：2001-05-31
申请人： Lin Wang , Elisabeth Hauptman , Lynda Kaye Johnson , Elizabeth Forrester McCord , Ying Wang , Steven Dale Ittel
发明人： Lin Wang , Elisabeth Hauptman , Lynda Kaye Johnson , Elizabeth Forrester McCord , Ying Wang , Steven Dale Ittel
IPC分类号： C07C251/08 , B01J31/00 , C07C251/20 , C07C251/24 , C07F5/06 , C07F7/00 , C07F9/50 , C07F9/572 , C07F9/58 , C07F15/04 , C07F19/00 , C08F4/00 , C08F4/06 , C08F4/16 , C08F4/44 , C08F4/60 , C08F4/605 , C08F4/619 , C08F4/642 , C08F4/70 , C08F4/76 , C08F4/80 , C08F10/00 , C08F10/02 , C08F110/02 , C08F118/02 , C08F210/00 , C08F210/02
CPC分类号： C08F10/00 , B01J31/1805 , B01J31/2282 , B01J2231/122 , B01J2531/847 , C07F9/46 , C07F9/5004 , C07F9/5009 , C07F15/0066 , C07F15/04 , C07F15/045 , C08F4/619 , C08F110/02 , C08F210/02 , C08F2500/04 , C08F2500/10 , C08F2500/20 , C08F220/10 , C08F2500/03 , C08F220/12 , C08F4/6028 , C08F4/64065 , C08F4/7031 , C08F4/7029 , C08F4/7019 , C08F4/7022 , C08F4/7014 , C08F4/7008 , C08F4/7006 , C08F4/40
摘要： Transition metal complexes of selected monoanionic phosphine ligands, which also contain a selected Group 15 or 16 (IUPAC) element and which are coordinated to a Group 3 to 11 (IUPAC) transition metal or a lanthanide metal, are polymerization catalysts for the (co)polymerization of olefins such as ethylene and α-olefins, and the copolymerization of such olefins with polar group-containing olefins. These and other nickel complexes of neutral and monoanionic bidentate ligands copolymerize ethylene and polar comonomers, especially acrylates, at relatively high ethylene pressures and surprisingly high temperatures, and give good incorporation of the polar comonomers and good polymer productivity. These copolymers are often unique structures, which are described.

7. 发明申请

US20050090381A1 Catalysts containing per-ortho aryl substituted aryl or heteroaryl substituted nitrogen donors 失效
标题翻译：含有邻邻芳基取代的芳基或杂芳基取代的氮供体的催化剂
公开(公告)号：US20050090381A1
公开(公告)日：2005-04-28
申请号：US10990955
申请日：2004-11-18
申请人： Leslie Moody , Peter Mackenzie , Christopher Killian , Gino Lavoie , James Ponasik , Thomas Smith , Jason Pearson , Anthony Gerard Barrett
发明人： Leslie Moody , Peter Mackenzie , Christopher Killian , Gino Lavoie , James Ponasik , Thomas Smith , Jason Pearson , Anthony Gerard Barrett
IPC分类号： C07C2/32 , C07C205/06 , C07C211/52 , C07C233/56 , C07C251/08 , C07C251/20 , C07C257/02 , C07C257/14 , C07D207/32 , C07D207/34 , C07D207/50 , C07D209/48 , C07D265/30 , C07D295/30 , C07D309/34 , C07D319/12 , C07D339/08 , C07D401/14 , C07D409/14 , C07F7/00 , C07F7/08 , C07F15/04 , C07F17/00 , C08F4/02 , C08F4/659 , C08F4/70 , C08F10/00 , C08F110/02 , C08F110/14 , C08F210/16 , B01J31/00 , C07F15/00
CPC分类号： C07D295/30 , C07C2/32 , C07C205/06 , C07C211/52 , C07C233/56 , C07C251/08 , C07C251/20 , C07C257/02 , C07C257/14 , C07C2531/22 , C07C2603/20 , C07D207/32 , C07D207/34 , C07D207/50 , C07D209/48 , C07D265/30 , C07D309/34 , C07D319/12 , C07D339/08 , C07D401/14 , C07D409/14 , C07F7/003 , C07F7/0812 , C07F15/045 , C07F17/00 , C08F10/00 , C08F110/02 , C08F110/14 , C08F210/16 , C08F4/80 , C08F2500/03 , C08F2500/09 , C08F2500/02 , C08F2500/04 , C08F2500/10 , C08F210/14 , C08F4/7006 , C08F4/7027
摘要： Catalyst compositions useful for the polymerization of olefins are disclosed. These compositions comprise a Group 8-10 metal complex comprising a bidentate or variable denticity ligand comprising one or two nitrogen donor atom or atoms independently substituted by an aromatic or heteroaromafic ring(s), wherein the ortho positions of said ring(s) are substituted by aryl or heteroaryl groups. Also disclosed are processes for the polymerization of olefins using the catalyst compositions.
摘要翻译：公开了可用于烯烃聚合的催化剂组合物。这些组合物包含第8-10族金属络合物，其包含二齿或可变牙齿配体，其包含一个或两个氮原子或独立地被芳族或杂芳香烃环取代的原子，其中所述环的邻位被取代通过芳基或杂芳基。还公开了使用催化剂组合物使烯烃聚合的方法。

8. 发明申请

US20050069795A1 Organophotoreceptor with charge transport material having bis(9-fluorenone) azine groups 失效
标题翻译：具有双（9-芴酮）吖嗪基的电荷传输材料的有机光感受器
公开(公告)号：US20050069795A1
公开(公告)日：2005-03-31
申请号：US10671255
申请日：2003-09-25
申请人： Nusrallah Jubran , Zbigniew Tokarski , Kam Law
发明人： Nusrallah Jubran , Zbigniew Tokarski , Kam Law
IPC分类号： C07C251/20 , C07C251/88 , C07C317/22 , C07C327/16 , C07C327/30 , C07D285/125 , G03G5/06 , G03G15/06 , C07C251/84 , G03G9/08
CPC分类号： G03G5/0633 , C07D285/125 , G03G5/0616 , G03G5/0618 , G03G5/062
摘要： Improved organophotoreceptor comprises an electrically conductive substrate and a photoconductive element on the electrically conductive substrate, the photoconductive element comprising: (a) a charge transport material having the formula where n is an integer between 2 and 6, inclusive; R1 and R2 are, independently, H, halogen, carboxyl, hydroxyl, thiol, cyano, nitro, aldehyde group, ketone group, an ether group, an ester group, a carbonyl group, an alkyl group, an alkaryl group, or an aryl group; X is a linking group having the formula —(CH2)m—, branched or linear, where m is an integer between 0 and 20, inclusive, and one or more of the methylene groups can be optionally replaced by O, S, C═O, O═S═O, a heterocyclic group, an aromatic group, urethane, urea, an ester group, a NR3 group, a CHR4 group, or a CR5R6 group where R3, R4, R5, and R6 are, independently, H, an alkyl group, an alkaryl group, a heterocyclic group, or an aryl group; Y comprises a bond, C, N, O, S, a branched or linear —(CH2)p— group where p is an integer between 0 and 10, an aromatic group, a cycloalkyl group, a heterocyclic group, or a NR9 group where R9 is hydrogen atom, an alkyl group, or aryl group, wherein Y has a structure selected to form n bonds with the corresponding X groups; and Z is a fluorenylidene group; and (b) a charge generating compound. Corresponding electrophotographic apparatuses and imaging methods are described.
摘要翻译：改进的有机光感受器包括在导电衬底上的导电衬底和光电导元件，光电导元件包括：（a）具有下式的电荷传输材料，其中n是2和6之间的整数，包括端值; R 1和R 2独立地是H，卤素，羧基，羟基，硫醇，氰基，硝基，醛基，酮基，醚基，酯基，羰基，烷基，烷芳基或芳基组; X是具有式 - （CH2）m-，分支或直链的连接基团，其中m是0和20之间的整数，包括1和20个，并且一个或多个亚甲基可以任选地被O，S，C = O，O = S = O，杂环基，芳基，氨基甲酸酯，脲，酯基，NR 3基，CHR 4基或CR 5 R 6基，其中R 3，R 4，R 5和R 6独立地为H ，烷基，烷芳基，杂环基或芳基; Y包括键，C，N，O，S，分支或线性 - （CH 2）p基团，其中p是0和10之间的整数，芳族基团，环烷基，杂环基或NR 9基团其中R9是氢原子，烷基或芳基，其中Y具有选择与相应X基团形成n键的结构; Z为亚芴基; 和（b）电荷产生化合物。描述相应的电子照相设备和成像方法。

9. 发明申请

US20050043496A1 Catalysts for olefin polymerization 失效
标题翻译：用于烯烃聚合的催化剂
公开(公告)号：US20050043496A1
公开(公告)日：2005-02-24
申请号：US10943199
申请日：2004-09-16
申请人： Lin Wang , Elisabeth Hauptman , Lynda Johnson , Elizabeth McCord , Stephan McLain , Ying Wang
发明人： Lin Wang , Elisabeth Hauptman , Lynda Johnson , Elizabeth McCord , Stephan McLain , Ying Wang
IPC分类号： C07C251/08 , B01J31/00 , C07C251/20 , C07C251/24 , C07F5/06 , C07F7/00 , C07F9/50 , C07F9/572 , C07F9/58 , C07F15/04 , C07F19/00 , C08F4/00 , C08F4/06 , C08F4/16 , C08F4/44 , C08F4/60 , C08F4/605 , C08F4/619 , C08F4/642 , C08F4/70 , C08F4/76 , C08F4/80 , C08F10/00 , C08F10/02 , C08F110/02 , C08F118/02 , C08F210/00 , C08F210/02
CPC分类号： C08F10/00 , B01J31/1805 , B01J31/2282 , B01J2231/122 , B01J2531/847 , C07F9/46 , C07F9/5004 , C07F9/5009 , C07F15/0066 , C07F15/04 , C07F15/045 , C08F4/619 , C08F110/02 , C08F210/02 , C08F2500/04 , C08F2500/10 , C08F2500/20 , C08F220/10 , C08F2500/03 , C08F220/12 , C08F4/6028 , C08F4/64065 , C08F4/7031 , C08F4/7029 , C08F4/7019 , C08F4/7022 , C08F4/7014 , C08F4/7008 , C08F4/7006 , C08F4/40
摘要： Transition metal complexes of selected monoanionic phosphine ligands, which also contain a selected Group 15 or 16 (IUPAC) element and which are coordinated to a Group 3 to 11 (IUPAC) transition metal or a lanthanide metal, are polymerization catalysts for the (co)polymerization of olefins such as ethylene and α-olefins, and the copolymerization of such olefins with polar group-containing olefins. These and other nickel complexes of neutral and monoanionic bidentate ligands copolymerize ethylene and polar comonomers, especially acrylates, at relatively high ethylene pressures and surprisingly high temperatures, and give good incorporation of the polar comonomers and good polymer productivity. These copolymers are often unique structures, which are described.
摘要翻译：还包含选定的第15或16族（IUPAC）元素并且与第3至11族（IUPAC）过渡金属或镧系元素金属配位的选择性单阴离子膦配体的过渡金属络合物是用于（共）烯烃如乙烯和α-烯烃的聚合，以及这些烯烃与极性基团烯烃的共聚。中性和单阴离子双齿配体的这些和其它镍配合物在相对高的乙烯压力和惊人的高温下共聚乙烯和极性共聚单体，特别是丙烯酸酯，并且使极性共聚单体具有良好的掺入性和良好的聚合物生产率。这些共聚物通常是独特的结构，其被描述。

10. 发明授权

US5268508A Method for manufacturing 3-amino-2-cyclohexene-1-one, and a novel polymer ingredient and its preparation 失效
标题翻译： 3-氨基-2-环己烯-1-酮的制备方法和新型聚合物成分及其制备方法
公开(公告)号：US5268508A
公开(公告)日：1993-12-07
申请号：US929904
申请日：1992-08-17
申请人： Stephen E. Jacobson
发明人： Stephen E. Jacobson
IPC分类号： C07C225/20 , C07C251/20 , C07C249/02
CPC分类号： C07C225/20 , C07C251/20
摘要： A method of manufacturing 3-amino-2-cyclohexene-1-one by hydrogenating m-phenylenediamene to produce a novel intermediate salt of 3-amino-2-cyclohexene-1-imine followed by hydrolysis to produce 3-amino-2-cyclohexene-1-one. The novel intermediate 3-amino-2-cyclohexene-1-imine has also be isolated.
摘要翻译：通过氢化间苯二胺来制备3-氨基-2-环己烯-1-酮的新型3-氨基-2-环己烯-1-亚胺的中间体盐，随后水解产生3-氨基-2-环己烯 -1。新型中间体3-氨基-2-环己烯-1-亚胺也被分离。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式