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1. 发明授权

US09023584B2 Radiation-sensitive composition, and compound 有权
标题翻译：辐射敏感组合物和化合物
公开(公告)号：US09023584B2
公开(公告)日：2015-05-05
申请号：US13901621
申请日：2013-05-24
申请人： JSR Corporation
发明人： Ken Maruyama
IPC分类号： G03F7/004 , G03F7/027 , C07C309/00 , C07C315/00 , C07C303/00 , C07C309/27 , C07C381/12 , G03F7/039 , G03F7/20
CPC分类号： G03F7/004 , C07C309/27 , C07C381/12 , C07C2601/14 , C07C2602/42 , C07C2603/74 , G03F7/0045 , G03F7/0392 , G03F7/0397 , G03F7/2041 , Y10S430/114 , Y10S430/128
摘要： A radiation-sensitive composition includes a compound represented by a formula (1), and a polymer having a structural unit that includes an acid-labile group. In the formula (1), R1 represents a group having a polar group; n is an integer of 1 to 4, wherein, in a case where R1 is present in a plurality of number, the plurality of R1s are identical or different, and optionally at least two R1s taken together represent a cyclic structure; A represents an alicyclic hydrocarbon group having a valency of (n+1); and M+ represents a monovalent onium cation.
摘要翻译：辐射敏感性组合物包括由式（1）表示的化合物和具有包含酸不稳定基团的结构单元的聚合物。式（1）中，R 1表示具有极性基团的基团。 n为1〜4的整数，其中，R1为多个的情况下，多个R 1相同或不同，并且任选地，至少两个R 1一起表示环状结构。 A表示具有（n + 1）价的脂环族烃基; M +表示单价鎓阳离子。

2. 发明授权

US07781611B2 Nitro-sulfobenzamides 有权
标题翻译：硝基磺基苯甲酰胺
公开(公告)号：US07781611B2
公开(公告)日：2010-08-24
申请号：US09732006
申请日：2000-12-07
申请人： Mark James Ford , Jan Vermehren
发明人： Mark James Ford , Jan Vermehren
IPC分类号： C07C309/27 , C07C309/29
CPC分类号： C07C303/38 , C07C303/22 , C07C309/59 , C07C311/65 , C07D239/52 , C07D327/04 , C07C311/16 , C07C309/89
摘要： The present invention relates to a compound of the formula (I) wherein R1 is an unsubstituted or substituted hydrocarbon radical having a total of 1 to 10 carbon atoms, preferably 1 to 6 carbon atoms, R2 is an unsubstituted or substituted hydrocarbon radical having a total of 1 to 10 carbon atoms, preferably 1 to 6 carbon atoms, or the group NR1R2 is a heterocyclic ring having 3 to 8 ring atoms which is unsubstituted or substituted and contains the nitrogen atom of the group NR1R2 as ring heteroatom and may also contain one or two further ring heteroatoms from the group consisting of N, O and S, and Q is H or a cation. The compounds of the present invention can advantageously be used for the preparation of sulfonylureas and their precursors such as sulfochlorides or sulfonamides.
摘要翻译：本发明涉及式（I）化合物，其中R 1是总共具有1至10个碳原子，优选1至6个碳原子的未取代或取代的烃基，R 2是未取代或取代的烃基，其具有总计 1〜10个碳原子，优选1〜6个碳原子，或者NR1R2是具有3〜8个环原子的杂环，其未被取代或取代，并且含有NR1R2基团的氮原子作为环杂原子，并且还可以含有一个或另外两个来自N，O和S的环杂原子，Q是H或阳离子。本发明的化合物可以有利地用于制备磺酰脲类及其前体如磺酰氯或磺酰胺。

3. 发明授权

US09720322B2 Photoresist composition, compound, and production method thereof 有权
公开(公告)号：US09720322B2
公开(公告)日：2017-08-01
申请号：US15252553
申请日：2016-08-31
申请人： JSR CORPORATION
发明人： Hayato Namai , Norihiko Ikeda , Takanori Kawakami
IPC分类号： G03F7/004 , C07C381/12 , C07D307/93 , C07D307/94 , C07D311/74 , C07D313/06 , C07D317/24 , C07D319/06 , C07D321/12 , C07D327/04 , C07C309/17 , C07D237/04 , C07D237/16 , C07D493/10 , C07D207/416 , C07D211/46 , C07D295/18 , C07D307/33 , C07D307/64 , C07C309/27 , G03F7/039 , G03F7/11 , G03F7/20 , G03F7/027 , G03F7/038 , C07C309/18 , C07D295/185 , C07D307/60 , C07D311/20
CPC分类号： G03F7/0045 , C07C309/17 , C07C309/18 , C07C309/27 , C07C381/12 , C07C2601/08 , C07C2601/10 , C07C2601/14 , C07C2601/18 , C07C2603/74 , C07D207/416 , C07D211/46 , C07D237/04 , C07D237/16 , C07D295/18 , C07D295/185 , C07D307/33 , C07D307/60 , C07D307/64 , C07D307/93 , C07D307/94 , C07D311/20 , C07D311/74 , C07D313/06 , C07D317/24 , C07D319/06 , C07D321/12 , C07D327/04 , C07D493/10 , G03F7/0046 , G03F7/027 , G03F7/038 , G03F7/0388 , G03F7/039 , G03F7/0392 , G03F7/0397 , G03F7/11 , G03F7/2041
摘要： A photoresist composition containing (A) a polymer having a structural unit (I) that includes an acid-labile group, and (I) a compound represented by the following formula (1). In the following formula (1), R1, R2, R3 and R represent a hydrogen atom or a monovalent organic group having 1 to 20 carbon atoms. X represents a single bond, an oxygen atom or —NRa—. Ra represents a hydrogen atom, a hydroxy group or a monovalent organic group having 1 to 20 carbon atoms, and optionally taken together represents a ring structure by binding with R each other. A− represents —SO3− or —CO2−. M+ represents a monovalent onium cation.

4. 发明授权

US6054448A 2-amino-2-(3-substituted cyclobutyl) acetic acid derivatives 失效
标题翻译： 2-氨基-2-（3-取代的环丁基）乙酸衍生物
公开(公告)号：US6054448A
公开(公告)日：2000-04-25
申请号：US954675
申请日：1997-10-17
申请人： Barry Peter Clark , John Richard Harris
发明人： Barry Peter Clark , John Richard Harris
IPC分类号： C07D335/14 , A61K31/135 , A61K31/35 , A61K31/352 , A61K31/38 , A61K31/382 , A61P25/00 , C07C229/28 , C07C229/36 , C07C305/12 , C07C305/16 , C07C305/20 , C07C309/19 , C07C309/23 , C07C309/27 , C07C313/12 , C07C313/14 , C07D311/86 , C07D311/90 , C07D335/16 , C07D335/20 , C07F9/144 , C07F9/40 , C07F9/48 , A61K31/195 , A61K31/66 , C07C61/04
CPC分类号： C07D335/20 , C07C229/36 , C07D311/90 , C07C2101/04
摘要： Compounds of the formula ##STR1## in which R.sup.1 is Y or Y--C.sub.1-6 alkyl, where Y is carboxy, tetrazolyl, --SO.sub.2 H, --SO.sub.3 H, --OSO.sub.3 H, --CONHOH, or --P(OH)OR', --PO(OH)OR', --OP(OH)OR' or --OPO(OH)OR' where R' is hydrogen, C.sub.1-6 alkyl, C.sub.2-6 alkenyl or optionally substituted phenyl-C.sub.1-6 alkyl,and R.sup.2, R.sup.3, R.sup.4, X and Z are as defined in the specification, possess affinity for metabotropic glutamate receptors and are useful in the treatment of disorders of the central nervous system.
摘要翻译：其中R 1是Y或Y-C 1-6烷基，其中Y是羧基，四唑基，-SO 2 H，-SO 3 H，-OSO 3 H，-CONHOH或-P（OH）OR'，-PO（OH） OR'，-OP（OH）OR'或-OPO（OH）OR'，其中R'是氢，C 1-6烷基，C 2-6烯基或任选取代的苯基-C 1-6烷基，R 2，R 3，R 4， X和Z如说明书中所定义，对代谢型谷氨酸受体具有亲和力，可用于治疗中枢神经系统疾病。

5. 发明授权

US5549886A Photostable filtering cosmetic composition 失效
公开(公告)号：US5549886A
公开(公告)日：1996-08-27
申请号：US332065
申请日：1994-11-01
申请人： Jean F. Grollier
发明人： Jean F. Grollier
IPC分类号： A61K8/00 , A61K8/31 , A61K8/34 , A61K8/35 , A61K8/36 , A61K8/37 , A61K8/46 , A61K8/92 , A61K8/97 , A61K8/98 , A61K9/12 , A61Q17/04 , C07C49/683 , C07C49/784 , C07C49/84 , C07C309/27 , C07C311/14 , A61K7/42
CPC分类号： A61K8/35 , A61K8/466 , A61Q17/04 , A61K2800/52 , Y10S514/847 , Y10S514/938
摘要： The invention relates to a photostable filtering emulsion containing in association, in the aqueous phase, a photostable filter with a wide absorption band constituted by partially or totally neutralized benzene-1,4-[di(3-methylidene-10-camphosulphonic)] acid, and in the oily phase a photostable system which filters the UV-A rays containing at least one of the following compounds: N-(2-ethylhexyl)-3-[(3'-methoxy-4'-n-butoxy)benzylidene]-10-camphosulphonamide (compound 2), 4-(1,1-dimethylethyl)-4'-methoxydibenzoylmethane (compound 3) and 4-isopropyldibenzoylmethane (compound 4), these two latter compounds 3 and 4 being photochemically stabilized by at least one fat-soluble filter of .lambda..sub.max less than 330 nm chosen from the following benzylidene camphor derivatives: benzylidene camphor (compound 5), p-methylbenzylidene camphor (compound 6), N-(2-ethylhexyl)-4-(3'-methylidene camphor)benzene sulphonamide (compound 7) and 3-methoxy-4-n-butoxybenzylidene camphor (compound 8).This composition is intended to protect the skin from UV rays of wavelengths between 280 and 380 nm.

6. 发明授权

US5514683A Bicyclo 2,2,2!octane derivatives 失效
标题翻译：双环[2,2,2]辛烷衍生物
公开(公告)号：US5514683A
公开(公告)日：1996-05-07
申请号：US288185
申请日：1994-08-09
申请人： Sarkis B. Kalindjian , Caroline M. R. Low , Iain M. McDonald , Robert A. D. Hull , Nigel P. Shankley , Ildiko M. Buck , Katherine I. M. Steel , Jonathan M. R. Davies , David J. Dunstone , Elaine A. Harper , Michael J. Pether , Michael J. Bodkin , Matthew J. Tozer , Martin L. Hudson
发明人： Sarkis B. Kalindjian , Caroline M. R. Low , Iain M. McDonald , Robert A. D. Hull , Nigel P. Shankley , Ildiko M. Buck , Katherine I. M. Steel , Jonathan M. R. Davies , David J. Dunstone , Elaine A. Harper , Michael J. Pether , Michael J. Bodkin , Matthew J. Tozer , Martin L. Hudson
IPC分类号： A61K38/00 , C07C69/00 , C07C233/11 , C07C233/58 , C07C233/61 , C07C233/63 , C07C237/22 , C07C255/29 , C07C309/27 , C07C323/41 , C07D207/16 , C07D209/16 , C07D209/20 , C07D211/60 , C07D217/26 , C07D257/04 , C07D307/52 , C07D307/68 , C07D333/20 , C07D405/12 , C07K5/065 , C07K5/078 , A61K31/435 , A61K31/34 , A61K31/38 , A61K31/41
CPC分类号： C07D257/04 , C07C233/11 , C07C233/58 , C07C233/61 , C07C233/63 , C07C237/22 , C07C255/29 , C07C309/27 , C07C323/41 , C07C69/00 , C07D207/16 , C07D209/16 , C07D209/20 , C07D211/60 , C07D217/26 , C07D307/52 , C07D307/68 , C07D333/20 , C07D405/12 , C07K5/06078 , C07K5/06139 , C07K5/06156 , C07K5/06165 , C07K5/06173 , A61K38/00 , C07C2101/14 , C07C2101/18 , C07C2102/42 , C07C2103/00 , C07C2103/74 , C07C2103/88
摘要： The compounds of the formula I ##STR1## and their pharmaceutical acceptable salts, which are defined herein, are ligands for cholecystokinin and/or gastrin receptors.
摘要翻译：本文定义的式I化合物（I）及其药学上可接受的盐是缩胆囊素和/或胃泌素受体的配体。

7. 发明申请

US20210017137A1 SALTS OF AN EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR 有权
公开(公告)号：US20210017137A1
公开(公告)日：2021-01-21
申请号：US16797776
申请日：2020-02-21
申请人： Celgene CAR LLC
发明人： Mei Lai , Steven Richard Witowski , Richland Wayne Tester , Kwangho Lee
IPC分类号： C07D239/48 , C07C55/02 , C07C55/07 , C07C62/02 , C07C309/04 , C07C309/05 , C07C309/27 , C07C309/29 , C07C309/30 , C07C309/35
摘要： The present invention provides a salt form and compositions thereof, which are useful as an inhibitor of EGFR kinases and which exhibits desirable characteristics for the same.

8. 发明申请

US20170217904A1 SALTS OF AN EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR 有权
公开(公告)号：US20170217904A1
公开(公告)日：2017-08-03
申请号：US15401637
申请日：2017-01-09
申请人： Celgene CAR LLC
发明人： Mei Lai , Steven Richard Witowski , Richland Wayne Tester , Kwangho Lee
IPC分类号： C07D239/48 , C07C309/27 , C07C309/05 , C07C62/02 , C07C309/04 , C07C309/35 , C07C55/07 , C07C309/30 , C07C309/29 , C07C55/02
CPC分类号： C07D239/48 , C07B2200/13 , C07C55/02 , C07C55/07 , C07C62/02 , C07C309/04 , C07C309/05 , C07C309/27 , C07C309/29 , C07C309/30 , C07C309/35
摘要： The present invention provides a salt form and compositions thereof, which are useful as an inhibitor of EGFR kinases and which exhibits desirable characteristics for the same.

9. 发明申请

US20160370700A1 PHOTORESIST COMPOSITION, COMPOUND, AND PRODUCTION METHOD THEREOF 有权
公开(公告)号：US20160370700A1
公开(公告)日：2016-12-22
申请号：US15252553
申请日：2016-08-31
申请人： JSR CORPORATION
发明人： Hayato NAMAI , Norihiko IKEDA , Takanori KAWAKAMI
IPC分类号： G03F7/004 , G03F7/038 , C07D207/416 , C07C381/12 , C07D295/185 , C07D493/10 , C07D307/94 , C07D311/20 , C07C309/17 , C07D317/24 , C07D307/93 , C07D327/04 , C07D307/33 , C07D307/60 , C07D211/46 , C07D237/04 , C07C309/18 , C07D319/06 , C07C309/27 , C07D321/12 , G03F7/039
CPC分类号： G03F7/0045 , C07C309/17 , C07C309/18 , C07C309/27 , C07C381/12 , C07C2601/08 , C07C2601/10 , C07C2601/14 , C07C2601/18 , C07C2603/74 , C07D207/416 , C07D211/46 , C07D237/04 , C07D237/16 , C07D295/18 , C07D295/185 , C07D307/33 , C07D307/60 , C07D307/64 , C07D307/93 , C07D307/94 , C07D311/20 , C07D311/74 , C07D313/06 , C07D317/24 , C07D319/06 , C07D321/12 , C07D327/04 , C07D493/10 , G03F7/0046 , G03F7/027 , G03F7/038 , G03F7/0388 , G03F7/039 , G03F7/0392 , G03F7/0397 , G03F7/11 , G03F7/2041
摘要： A photoresist composition containing (A) a polymer having a structural unit (I) that includes an acid-labile group, and (I) a compound represented by the following formula (1). In the following formula (1), R1, R2, R3 and R represent a hydrogen atom or a monovalent organic group having 1 to 20 carbon atoms. X represents a single bond, an oxygen atom or —NRa—. Ra represents a hydrogen atom, a hydroxy group or a monovalent organic group having 1 to 20 carbon atoms, and optionally taken together represents a ring structure by binding with R each other. A− represents —SO3− or —CO2−. M+ represents a monovalent onium cation.

10. 发明授权

US5393515A Photostable filtering cosmetic composition 失效
标题翻译： Photostable过滤化妆品组合物
公开(公告)号：US5393515A
公开(公告)日：1995-02-28
申请号：US854883
申请日：1992-03-20
申请人： Jean F. Grollier
发明人： Jean F. Grollier
IPC分类号： A61K8/00 , A61K8/31 , A61K8/34 , A61K8/35 , A61K8/36 , A61K8/37 , A61K8/46 , A61K8/92 , A61K8/97 , A61K8/98 , A61K9/12 , A61Q17/04 , C07C49/683 , C07C49/784 , C07C49/84 , C07C309/27 , C07C311/14 , A61K7/42 , A61K7/44 , A61K7/48
CPC分类号： A61K8/35 , A61K8/466 , A61Q17/04 , A61K2800/52 , Y10S514/847 , Y10S514/938
摘要： The invention relates to a photostable filtering emulsion containing in association, in the aqueous phase, a photostable filter with a wide absorption band constituted by partially or totally neutralized benzene-1,4-[di(3-methylidene-10-camphosulphonic)] acid, and in the oily phase a photostable system which filters the UV-A rays containing at least one of the following compounds: N-(2-ethylhexyl)-3-[(3'-methoxy-4'-n-butoxy)benzylidene]-10-camphosulphonamide (compound 2), 4-(1,1-dimethylethyl)-4'-methoxydibenzoylmethane (compound 3) and 4-isopropyldibenzoylmethane (compound 4), these two latter compounds 3 and 4 being photochemically stabilized by at least one fat-soluble filter of .lambda..sub.max less than 330 nm chosen from the following benzylidene camphor derivatives: benzylidene camphor (compound 5), p-methylbenzylidene camphor (compound 6), N-(2-ethylhexyl)-4-(3'-methylidene camphor)benzene sulphonamide (compound 7) and 3-methoxy-4-n-butoxybenzylidene camphor (compound 8).This composition is intended to protect the skin from UV rays of wavelengths between 280 and 380 nm.
摘要翻译：本发明涉及一种光稳定性过滤乳液，其在水相中包含具有宽部分或全部中和的苯-1,4- [二（3-亚甲基-10-磺基磺酸）]酸的宽吸收带的光稳定过滤器并且在油相中是一种过滤含有至少一种以下化合物的UV-A射线的光稳定系统：N-（2-乙基己基）-3 - [（3'-甲氧基-4'-正丁氧基）亚苄基（化合物2），4-（1,1-二甲基乙基）-4'-甲氧基二苯甲酰甲烷（化合物3）和4-异丙基二苯甲酰基甲烷（化合物4），这两种后者化合物3和4至少光化学稳定选自以下亚苄基樟脑衍生物：化合物5，对甲基亚苄基樟脑（化合物6），N-（2-乙基己基）-4-（3'- 亚甲基樟脑）苯磺酰胺（化合物7）和3-甲氧基-4-正丁氧基亚苄基樟脑（化合物8）。该组合物旨在保护皮肤免受280-380nm波长的紫外线。

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