专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明公开

US20230312454A1 6-HYDROXY-3-HEXENYL ALKOXYMETHYL ETHER COMPOUND AND A PROCESS FOR PREPARING A 3,13-OCTADECADIEN-1-OL COMPOUND FROM THE SAME 审中-公开
公开(公告)号：US20230312454A1
公开(公告)日：2023-10-05
申请号：US18303008
申请日：2023-04-19
申请人： Shin-Etsu Chemical Co., Ltd.
发明人： Yuki Miyake , Takeshi Kinsho , Yusuke Nagae
IPC分类号： C07C67/08 , C07C29/132 , C07C41/22 , C07C41/24 , C07C41/30 , C07C43/178
CPC分类号： C07C67/08 , C07C29/132 , C07C41/22 , C07C41/24 , C07C41/30 , C07C43/178
摘要： The present invention relates to a 6-hydroxy-3-hexenyl alkoxymethyl ether compound of the following general formula (1): HOCH2CH2CH=CHCH2CH2OCH2OCH2R1 (1), R1 representing a hydrogen atom, an n-alkyl group having 1 to 9 carbon atoms, or a phenyl group; and also relates to a process for preparing a 3,13-octadecadien-1-ol compound of the following formula (6): CH3(CH2)3CH=CH(CH2)8CH=CHCH2CH2OH (6) from the 6-hydroxy-3-hexenyl alkoxymethyl ether compound (1).

2. 发明授权

US10597346B2 Methods for producing solvents derived from 1-chloro-3, 3, 3-trifluoro-propene (1233zd) 有权
公开(公告)号：US10597346B2
公开(公告)日：2020-03-24
申请号：US16435877
申请日：2019-06-10
申请人： Honeywell International Inc.
发明人： Ya Qun Liu , Hong Min Huang , Jun Liu , Rajiv R. Singh
IPC分类号： C07C41/01 , C11D7/50 , A62D1/00 , C07C41/06 , C09K5/04 , C09K3/30 , C07C41/24 , C09K3/00 , C09K13/00 , C09K21/06 , C10M131/10 , C11D3/43
摘要： The production of solvents for applications such as heat transfer, cleaning, and degreasing, for example. In particular, the production of solvents derived from 1-chloro-3,3,3-trifluoro-propene, such as chloro and/or fluoro substituted alkanes and chloro and/or fluoro substituted trifluoropropenyl ethers.

3. 发明申请

US20170113989A1 SYNTHESIS OF HONOKIOL 审中-公开
公开(公告)号：US20170113989A1
公开(公告)日：2017-04-27
申请号：US15331640
申请日：2016-10-21
申请人： Colgate-Palmolive Company , The Trustees of the University of Pennsylvania
发明人： Stanislav JARACZ , Marisa KOZLOWSKI , Young EUN LEE , Sun Min KIM
IPC分类号： C07C37/055 , C07C37/14 , C07C41/24 , C07C41/09 , C07C41/22 , C07C39/21 , C07C37/50
CPC分类号： C07C37/0555 , C07C37/11 , C07C37/14 , C07C37/50 , C07C39/15 , C07C39/21 , C07C41/09 , C07C41/16 , C07C41/22 , C07C41/24 , C07C41/30 , C07C43/2055 , C07C43/225 , C07C43/215
摘要： Disclosed herein are improved methods for the synthesis of honokiol, as well as methods for the synthesis of 3,3′-di-tert-butyl-5,5′-dimethyl-[1,1′-biphenyl]-2,4′-diol, 3′,5-dimethyl-[1,1′-biphenyl]-2,4′-diol, and 2,4′-dimethoxy-3′,5-dimethyl-1,1′-biphenyl, 3,3′,5,5′-tetra-tert-butyl-[1,1′-biphenyl]-2,4′-diol, and certain tetrasubstituted bisphenols, and uses therefor.

4. 发明授权

US09309188B2 Method for allylating and vinylating aryl, heteroaryl, alkyl, and alkene halogenides using transition metal catalysis 有权
标题翻译：使用过渡金属催化烯化和烯化芳基，杂芳基，烷基和烯烃卤化物的方法
公开(公告)号：US09309188B2
公开(公告)日：2016-04-12
申请号：US13577278
申请日：2011-02-01
申请人： Matthias Gotta , Bernd Wilhelm Lehnemann , Waldemar Maximilian Czaplik , Matthias Mayer , Axel Jacobi Von Wangelin
发明人： Matthias Gotta , Bernd Wilhelm Lehnemann , Waldemar Maximilian Czaplik , Matthias Mayer , Axel Jacobi Von Wangelin
IPC分类号： C07B37/04 , C07B49/00 , C07C1/32 , C07C15/44 , C07C43/205 , C07C253/04 , C07C17/263 , C07C41/30 , C07C67/343 , C07C209/68 , C07C253/30 , C07C1/30 , C07C17/26 , C07C41/24 , C07C209/74
CPC分类号： C07C253/04 , C07B37/04 , C07B49/00 , C07C1/30 , C07C1/326 , C07C17/26 , C07C17/2632 , C07C41/24 , C07C41/30 , C07C67/343 , C07C209/68 , C07C209/74 , C07C253/30 , C07C2527/128 , C07C2531/22 , C07C2603/26 , C07C11/02 , C07C15/44 , C07C43/2055 , C07C43/205 , C07C69/612 , C07C25/24 , C07C211/48 , C07C255/50
摘要： What is described is a process for preparing organic compounds of the general formula (I) R—R′ (I) by converting a corresponding compound of the general formula (II) R—X (II) in which X is fluorine, chlorine, bromine or iodine to an organomagnesium compound of the general formula (III) [M+]n[RmMgXkY1] (III) wherein compounds of the formula (III) are reacted with a compound of the general formula (IV) characterized in that the reaction of (III) with (IV) is performed in the presence of a) catalytic amounts of an iron compound, based on the compound of the general formula (II), and optionally in the presence of b) a nitrogen-, oxygen- and/or phosphorus-containing additive in a catalytic or stoichiometric amount, based on the compound of the general formula (II).
摘要翻译：描述的是通过将相应的通式（II）化合物R-X（II）转化为其中X为氟，氯，氯，溴或碘与通式（III）的有机镁化合物[M +] n [RmMgXkY1]（III）反应，其中式（III）化合物与通式（IV）的化合物反应，其特征在于：（III）与（IV）的化合物在a）催化量的铁化合物存在下进行，基于通式（II）的化合物，并且任选在b）氮，氧和/ 或基于通式（II）的化合物的催化或化学计量的含磷添加剂。

5. 发明授权

US09212118B2 Synthesis of intermediates for preparing anacetrapib and derivatives thereof 有权
标题翻译：合成制备阿马斯他及其衍生物的中间体
公开(公告)号：US09212118B2
公开(公告)日：2015-12-15
申请号：US13996955
申请日：2011-12-21
申请人： Jan Humljan , Nenad Maras
发明人： Jan Humljan , Nenad Maras
IPC分类号： C07C41/24 , C07C41/18 , C07C41/30 , C07C41/26 , C07C45/68 , C07D263/22 , C07C253/30 , A61K31/421 , C07C41/22 , C07C43/225 , C07D263/20
CPC分类号： C07C41/26 , A61K31/421 , C07C41/18 , C07C41/22 , C07C41/30 , C07C43/225 , C07C45/68 , C07C253/30 , C07D263/20 , C07D263/22 , C07C43/23 , C07C47/277 , C07C255/54
摘要： The present invention relates to the field of organic chemistry, more specifically to the synthesis of intermediate compounds which can be used in the synthesis of pharmaceutically active agents such as anacetrapib or derivatives thereof.
摘要翻译：本发明涉及有机化学领域，更具体地涉及可用于合成药物活性剂如乙酰吡啶或其衍生物的中间体化合物的合成。

6. 发明授权

US08980124B2 Aromatic compound gelling agent having perfluoroalkyl group 有权
标题翻译：具有全氟烷基的芳族化合物胶凝剂
公开(公告)号：US08980124B2
公开(公告)日：2015-03-17
申请号：US12087998
申请日：2007-01-19
申请人： Hiroaki Okamoto , Yuki Morita
发明人： Hiroaki Okamoto , Yuki Morita
IPC分类号： H01M4/88 , C07C381/00 , C07C41/00 , C07C41/24 , C07C41/16 , C07C41/26 , C07C41/30 , C07C43/225 , C07C43/23 , C07C323/20 , H01M10/0525 , H01M10/0565
CPC分类号： C07C41/24 , C07C41/16 , C07C41/26 , C07C41/30 , C07C43/225 , C07C43/23 , C07C323/20 , H01M10/0525 , H01M10/0565 , H01M2300/0085 , Y02E60/122 , Y02P70/54 , C07C43/215
摘要： Aromatic compounds having a perfluoroalkyl group and a gelling agent for gelling an organic liquid which is composed of any one of them. This gelling agent can gel many kinds of organic liquids by adding a small amount thereof.
摘要翻译：具有全氟烷基的芳香族化合物和由任意一种构成的有机液体的凝胶化剂。该胶凝剂可以通过加入少量有机液体来凝胶化多种有机液体。

7. 发明申请

US20140303403A1 CHEMICALLY MODIFIED SMALL MOLECULES 有权
标题翻译：化学改性的小分子
公开(公告)号：US20140303403A1
公开(公告)日：2014-10-09
申请号：US14248245
申请日：2014-04-08
申请人： Nektar Therapeutics
发明人： Michael D. BENTLEY , Tacey X. Viegas , Richard R. Goodin , Lin Cheng , Xuan Zhao
IPC分类号： C07C41/24
CPC分类号： A61K9/007 , A61K31/167 , A61K31/485 , A61K47/60 , C07C41/24
摘要： Methods of modifying the rate of systemic absorption of a drug administered to a subject by a pulmonary route, the method comprising covalently conjugating a hydrophilic polymer to a drug, wherein the drug has a half-life of elimination from the lung of less than about 180 minutes, to form a drug-polymer conjugate, wherein the drug-polymer conjugate has a net hydrophilic character and a weight average molecular weight of from about 50 to about 20,000 Daltons, and wherein the half-life of elimination from the lung of the drug-polymer conjugate is at least about 1.5-fold greater than the half-life of elimination from the lung of the drug, wherein the half-life of elimination from the lung is measured by bronchoalveolar lavage followed by assaying residual lung material.
摘要翻译：通过肺途径改变施用于受试者的药物的全身吸收速率的方法，所述方法包括将亲水性聚合物与药物共价共轭，其中所述药物具有从肺中消除的半衰期小于约180 分钟，以形成药物 - 聚合物缀合物，其中药物 - 聚合物缀合物具有净亲水特性和约50至约20,000道尔顿的重均分子量，并且其中从药物的肺中消除的半衰期 - 聚合物缀合物比从药物肺消除的半衰期大至少约1.5倍，其中通过支气管肺泡灌洗测量肺部消除的半衰期，然后测定残留的肺部材料。

8. 发明申请

US20060252968A1 Dehalogenation process 有权
标题翻译：脱卤过程
公开(公告)号：US20060252968A1
公开(公告)日：2006-11-09
申请号：US11417159
申请日：2006-05-04
申请人： Ivan Wlassics , Vito Tortelli
发明人： Ivan Wlassics , Vito Tortelli
IPC分类号： C07C41/24
CPC分类号： C07C17/23 , C07C41/24 , C07C41/48 , C07C43/17 , C07D317/42 , C07C21/20 , C07C43/313
摘要： A process for obtaining vinyl compounds by dehalogenation of halofluorinated compounds having a linear, branched or cyclic structure, said halofluorinated compounds containing in the molecule at least one group: wherein Y1 and Y2, equal to or different from each other, are selected from Cl, Br, I; wherein the halofluorinated compounds are dehalogenated in the presence of a transition metal, or of transition metal couples, by operating in a biphasic system of solvents immiscible among each other, formed of a (per)fluorinated solvent and a dipolar aprotic or protic solvent (co-solvent), wherein the ratio moles co-solvent/equivalents of the halofluorinated compound ranges from 0.5 to 10, preferably from 0.5 to 5, still more preferably from 1 to 3.
摘要翻译：一种通过使具有直链，支链或环状结构的卤代氟化化合物脱卤获得乙烯基化合物的方法，所述卤代氟化物在分子中含有至少一个基团：其中Y 1和Y 2，彼此相同或不同，选自Cl，Br，I; 其中所述卤代氟化合物在过渡金属或过渡金属偶存在下通过在彼此不混溶的溶剂的双相体系中操作而脱卤，由（一个）氟化溶剂和偶极非质子或质子溶剂（共 - 溶剂），其中所述卤化氟化合物的共溶剂/当量的摩尔比为0.5至10，优选0.5至5，还更优选1至3。

9. 发明授权

US5674959A Peroxide curable fluoroelastomers, particularly suitable for manufacturing O-rings 失效
标题翻译：过氧化物固化的含氟弹性体，特别适用于制造O型圈
公开(公告)号：US5674959A
公开(公告)日：1997-10-07
申请号：US723928
申请日：1996-10-01
申请人： Vincenzo Arcella , Giulio Brinati , Margherita Albano , Vito Tortelli
发明人： Vincenzo Arcella , Giulio Brinati , Margherita Albano , Vito Tortelli
IPC分类号： F16J15/10 , C07C17/25 , C07C17/275 , C07C21/18 , C07C41/24 , C07C43/17 , C08F14/18 , C08F14/22 , C08F16/14 , C08F214/18 , C08F214/22 , C08F214/26 , C08F216/14 , C09K3/10 , C08F16/24
CPC分类号： C08F214/18 , C07C17/25 , C07C17/275
摘要： New fluoroelastomers are described, having iodine atoms in terminal position and monomeric units in the chain deriving from an iodinated olefin of formula: CHR.dbd.CH--Z--CH.sub.2 CHR--I (I) wherein: R is --H or --CH.sub.3 ; Z is a (per)fluoroalkylene radical C.sub.1 -C.sub.18, linear or branched, optionally containing one or more ether oxygen atoms, or a (per) fluoropolyoxyalkylene radical. These products, upon peroxide curing, require extremely short post-curing treatments (around 30-60 minutes at 180.degree.-230.degree. C.) and are characterized by compression set values lower than 25% (measured on O-rings at 200.degree. C. for 70 hours according to ASTM Standard D395 Method B).
摘要翻译：描述了新的含氟弹性体，其末端具有碘原子，并且衍生自下式的CH 2 CH = CH-Z-CH 2 CHR-I（I）的碘化烯烃链中的单体单元，其中：R为-H或-CH 3; Z是直链或支链（任选地含有一个或多个醚氧原子）或（全）氟聚氧亚烷基的（全）氟亚烷基C1-C18。过氧化物固化后，这些产品需要非常短的后固化处理（在180°-230℃下约30-60分钟），其特征在于压缩永久变形值低于25％（在200℃的O形环上测量）根据ASTM标准D395方法B）70小时。

10. 发明授权

US5654493A Process for preparing 4-bromophenyl alkyl ethers 失效
标题翻译：制备4-溴苯基烷基醚的方法
公开(公告)号：US5654493A
公开(公告)日：1997-08-05
申请号：US702812
申请日：1996-08-26
申请人： Thomas Wessel
发明人： Thomas Wessel
IPC分类号： C07C41/22 , C07C43/225 , C07C41/24
CPC分类号： C07C41/22
摘要： The present invention relates to a process for preparing 4-bromophenyl alkyl ethers by reacting phenyl alkyl ethers with bromine in a water-miscible solvent in the presence of an oxidizing agent which is able to oxidize hydrogen bromide to bromine.
摘要翻译：本发明涉及在能够将溴化氢氧化成溴的氧化剂的存在下，使苯基烷基醚与溴在水混溶性溶剂中反应来制备4-溴苯基烷基醚的方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式