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    • 10. 发明授权
    • Chlorinated 4-methylphthalic anhydrides
    • 氯化4-甲基邻苯二甲酸酐
    • US4302396A
    • 1981-11-24
    • US886563
    • 1978-04-24
    • Michihiro TsujimotoTsutomu NishizawaKiyoharu HasegawaNobuyoshi Abe
    • Michihiro TsujimotoTsutomu NishizawaKiyoharu HasegawaNobuyoshi Abe
    • C07D307/89C07C51/00C07C51/363C07C63/68C07C63/72C07C67/00C07C63/16
    • C07C63/68
    • Novel chlorinated 4-methylphthalic acids or anhydrides of the general formula ##STR1## wherein n is an integer of 1, 2 or 3, with the proviso that when n is 1, the chlorine atom is positioned at 3- or 5-position and when n is 2, the chlorine atoms are positioned at 3- and 5-positions. The new compounds are produced by dissolving 4-methylphthalic anhydride in concentrated sulfuric acid or fuming sulfuric acid to form a solution, and reacting the solution with chlorine at room temperature preferably in the presence of a catalytic amount of iodine, thereby to yield a crude product containing a mixture of chlorinated 4-methylphthalic acids. By subjecting the mixture to a thermal dehydration treatment in an inactive organic solvent, each of the chlorinated compounds may be isolated as its corresponding anhydride in the form of crystals.These chlorinated 4-methylphthalic anhydrides are valuable as intermediates for the preparation of dyestuffs or pigments.
    • 新型氯代4-甲基邻苯二甲酸或通式为“IMAGE”的酸酐,其中n为1,2或3的整数,条件是当n为1时,氯原子位于3-或5-位,当 n为2,氯原子位于3-和5-位。 新化合物通过将4-甲基邻苯二甲酸酐溶解在浓硫酸或发烟硫酸中而形成溶液,并在室温下优选在催化量的碘存在下使溶液与氯反应,从而得到粗产物 含有氯代4-甲基邻苯二甲酸的混合物。 通过在惰性有机溶剂中对混合物进行热脱水处理,可以将各氯化化合物作为其相应的酸酐以晶体的形式分离。 这些氯代4-甲基邻苯二甲酸酐作为制备染料或颜料的中间体是有价值的。