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1. 发明申请

WO2016191728A1 PERITONEAL DIALYSIS SYSTEMS AND METHODS 审中-公开
标题翻译： PERITONEAL DIALYSIS系统和方法
公开(公告)号：WO2016191728A1
公开(公告)日：2016-12-01
申请号：PCT/US2016/034780
申请日：2016-05-27
申请人： COOK INCORPORATED , BLATTER, Duane , HAHNE, Kalub , ISCH, Andrew , MILNER, Keith
发明人： BLATTER, Duane , HAHNE, Kalub , ISCH, Andrew , MILNER, Keith
IPC分类号： A61M1/28 , A61M1/16
CPC分类号： A61M1/287 , A61M1/1672 , A61M1/1678 , A61M1/1696 , A61M1/28 , A61M2205/50 , A61M2205/8206
摘要： Described are peritoneal, dialysis systems and methods that involve the use of first and second stage filtration of a used dialysate withdrawn from the peritoneal space of a patient. The first filtration stage forms a first retentate containing an osmotic agent and a first permeate containing water and nitrogen-containing waste products of the patient. The second filtration stage acts on the first permeate to form a second retentate containing nitrogen -containing waste products of the patient and a second permeate containing water. At least some of the water from the second permeate is combined with the first, retentate to form a regenerated peritoneal dialysis medium containing an amount of the osmotic agent. The regenerated peritoneal dialysis medium can be returned to the peritoneal space of the patient.
摘要翻译：描述的是腹膜，透析系统和方法，其涉及使用从患者的腹膜空间抽出的使用的透析液的第一和第二阶段过滤。第一过滤阶段形成含有渗透剂的第一渗余物和含有患者的水和含氮废物的第一渗透物。第二过滤阶段作用于第一渗透物以形成包含患者的含氮废物的第二渗余物和含有水的第二渗透物。将来自第二渗透物的至少一些水与第一渗透物合并以形成含有一定量渗透剂的再生的腹膜透析介质。再生的腹膜透析介质可以返回到患者的腹膜空间。

2. 发明申请

WO2011053422A1 COMPARTMENT SYNDROME TREATMENT METHOD AND SURGICAL INSTRUMENT FOR SAME 审中-公开
标题翻译：室内综合治疗方法和手术仪器
公开(公告)号：WO2011053422A1
公开(公告)日：2011-05-05
申请号：PCT/US2010/050473
申请日：2010-09-28
申请人： COOK INCORPORATED , MESSMER, Sarah
发明人： MESSMER, Sarah
IPC分类号： A61B17/32 , A61B17/29 , A61B17/3209 , A61B19/00
CPC分类号： A61B17/320016 , A61B17/320036 , A61B17/3209 , A61B2017/2927 , A61B2090/3925
摘要： A subcutaneous fasciotomy is performed to relieve pressure due to compartment syndrome. A small incision is made in a patient's skin. A surgical instrument is advanced through the entry location, and moved between the skin and the fascia of the patient to a remote location, with a cutter of the instrument in a stowed configuration. After reaching the remote location, the cutter is deployed to pierce an initial opening in the fascia at the remote location. The fascia is maintained adjacent a blade of the cutter via a notch shape that traps the fascia. The instrument is then withdrawn back toward the entry location with the blade incising the fascia to relieve pressure in the muscle compartment. The surgical instrument is then removed through the entry incision.
摘要翻译：进行皮下筋膜切开术以减轻由室间综合征引起的压力。在患者的皮肤上进行小切口。手术器械通过进入位置前进，并且在患者的皮肤和筋膜之间移动到远程位置，仪器的切割器处于收起的构型。在到达远程位置之后，切割器被部署以在远处的筋膜上穿透初始开口。筋膜通过捕获筋膜的凹口形状保持在切割器的刀片附近。然后将器械退回到进入位置，刀片切割筋膜以减轻肌肉隔离层中的压力。然后通过入口切口取出手术器械。

3. 发明申请

WO2011037866A1 VESSEL CLOSURE DEVICE 审中-公开
标题翻译：船舶关闭装置
公开(公告)号：WO2011037866A1
公开(公告)日：2011-03-31
申请号：PCT/US2010/049505
申请日：2010-09-20
申请人： COOK INCORPORATED , PAUL, Ram, H., Jr. , BATES, Brian, L. , STANLEY, Cleon, P.
发明人： PAUL, Ram, H., Jr. , BATES, Brian, L. , STANLEY, Cleon, P.
IPC分类号： A61B17/00 , A61B17/29
CPC分类号： A61B17/0057 , A61B17/29 , A61B2017/0034 , A61B2017/00473 , A61B2017/00575 , A61B2017/2905 , A61B2017/2931 , A61B2017/303
摘要： A device and system for closure of an opening formed in a body vessel includes a bioabsorbable grasping member and locking member. The grasping member includes grasping lingers that are radially collapsible to the closed positions by movement of the locking member over the fingers. A distal portion of the fingers is configured to grasp an outer wall portion of the body vessel surrounding the opening when the fingers are in the open position. Movement of the locking member can cause the fingers to at least substantially close the vessel opening. Structural features on the fingers and/or locking member can inhibit proximal or distal movement of the locking member when in a locking position. A detachable arm can be coupled to the grasping member to facilitate placement of the grasping member. A sheath can fit over the detachable arm and be configured to move the locking member over the fingers.
摘要翻译：用于封闭形成在体容器中的开口的装置和系统包括生物可吸收的抓持构件和锁定构件。抓持构件包括通过锁定构件在指状物上的移动而径向可折叠到关闭位置的抓握件。手指的远端部分构造成当手指处于打开位置时抓住围绕开口的身体血管的外壁部分。锁定构件的运动可导致手指至少基本上关闭容器开口。手指和/或锁定构件上的结构特征可以在锁定位置时阻止锁定构件的近端或远端运动。可拆卸臂可以联接到抓握构件以便于抓握构件的放置。护套可以装配在可拆卸臂上方并且被配置成使锁定构件移动超过手指。

4. 发明申请

WO2011022151A1 DETACHABLE EMBOLIZATION COIL 审中-公开
标题翻译：可拆卸嵌入式线圈
公开(公告)号：WO2011022151A1
公开(公告)日：2011-02-24
申请号：PCT/US2010/042592
申请日：2010-07-20
申请人： COOK INCORPORATED , TEKULVE, Kurt, J.
发明人： TEKULVE, Kurt, J.
IPC分类号： A61B17/12
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/1214 , A61B17/1215 , A61B2017/0065 , A61B2017/12054
摘要： An embolization delivery system (10) and a method of using said system by a physician to deliver an embolization coil (35) into the vasculature of a patient is disclosed. The embolization delivery system comprises a delivery tube (15) in the form of a catheter (15) or wire guide that may be reversibly inserted, a delivery catheter placed into the vasculature of a patient, a connector (30) disposed around and permanently coupled to the delivery tube, a detachable embolization coil disposed within a portion of the connector and held in place by compressive forces exerted by the connector, and a release mechanism (40) for detaching the embolization coil. The release mechanism includes a wire (50) with one end (51) being coupled to the catheter, a middle portion (52) being in contact with both the connector and coil, and a second end that may be manipulated in a predetermined manner by the attending physician. The manipulation of the wire splits part of the connector, thereby, reducing the compressive forces exerted by the connector onto the embolization coil and allowing the coil to detach from the embolization delivery system.
摘要翻译：公开了栓塞输送系统（10）和由医师使用所述系统将栓塞线圈（35）输送到患者的脉管系统中的方法。栓塞递送系统包括导管（15）形式的输送管（15）或可逆地插入的导线引导件，放置在患者脉管系统中的输送导管，连接器（30）设置在所述连接器的一部分内并且通过所述连接器施加的压缩力保持在适当位置的可拆卸栓塞线圈，以及用于分离所述栓塞线圈的释放机构（40）。所述释放机构包括线（50），其一端（51）联接到所述导管，与所述连接器和线圈两者接触的中间部分（52）以及可以以预定方式被操纵的第二端主治医师。线的操作分裂连接器的一部分，从而减小由连接器施加到栓塞线圈上的压缩力，并允许线圈从栓塞输送系统脱离。

5. 发明申请

WO2011005971A1 SPRING ACTION MEDICAL DEVICE 审中-公开
标题翻译：弹簧动作医疗装置
公开(公告)号：WO2011005971A1
公开(公告)日：2011-01-13
申请号：PCT/US2010/041382
申请日：2010-07-08
申请人： COOK INCORPORATED , DECKARD, Michael, D. , HARDERT, Michael, W. , KAY, Thomas, A. Jr. , MOORE, William, F. , ELSESSER, James, C. , LENTZ, David, C. , MELSHEIMER, Jeffry, S.
发明人： DECKARD, Michael, D. , HARDERT, Michael, W. , KAY, Thomas, A. Jr. , MOORE, William, F. , ELSESSER, James, C. , LENTZ, David, C. , MELSHEIMER, Jeffry, S.
IPC分类号： A61M25/09 , A61B17/22
CPC分类号： A61M25/09025 , A61B17/22012 , A61B2017/22038 , A61B2017/22069 , A61B2017/22094
摘要： A spring action medical device includes a spring that may propel a hammer component in a distal direction when the spring is released from a loaded state. When propelled forward by the spring, the hammer component makes contact with a distal tip of the medical device. The distal tip may then transfer a force to an external object, such as an occlusion in a body lumen.
摘要翻译：弹簧动作医疗装置包括弹簧，当弹簧从负载状态释放时，弹簧可以沿远侧方向推进锤部件。当弹簧向前推进时，锤子部件与医疗装置的远端接触。然后，远侧末端可以将力传递到外部物体，例如体腔内的闭塞。

6. 发明申请

WO2010126786A1 ASPIRATION CATHETER WITH THROMBUS REMOVING DEVICE 审中-公开
标题翻译：吸入式导管与THROMBUS移除装置
公开(公告)号：WO2010126786A1
公开(公告)日：2010-11-04
申请号：PCT/US2010/032171
申请日：2010-04-23
申请人： COOK INCORPORATED , TEKULVE, Kurt J. , CAVETT, Meridith A.
发明人： TEKULVE, Kurt J. , CAVETT, Meridith A.
IPC分类号： A61M25/00 , A61B19/00
CPC分类号： A61M25/0068 , A61B2017/320012 , A61B2090/701 , A61M25/0082 , A61M2025/0019 , A61M2025/0096
摘要： The present disclosure provides an aspiration catheter (20) for removing thrombus from a lumen of a hemodialysis catheter (100). One embodiment of the aspiration catheter comprises an elongate flexible shaft having a proximal end and a distal end. The aspiration catheter further comprises an operable device at the distal end of the elongate flexible shaft to be inserted through the lumen of the hemodialysis catheter. The operable device (30) is capable of being extended beyond a distal end of the lumen of the hemodialysis catheter. The operable device is configured to engage and remove thrombus from the lumen of the hemodialysis catheter. The aspiration catheter further comprises a source of negative pressure. The aspiration catheter further comprises a connector adapted to connect the source of negative pressure and the proximal end of the elongate flexible shaft. The elongate flexible shaft is configured to draw debris into the aspiration catheter.
摘要翻译：本公开提供了一种用于从血液透析导管（100）的内腔去除血栓的抽吸导管（20）。抽吸导管的一个实施例包括具有近端和远端的细长柔性轴。抽吸导管还包括在细长柔性轴的远端处的可操作装置，以插入通过血液透析导管的内腔。可操作装置（30）能够延伸超过血液透析导管的内腔的远端。可操作装置构造成从血液透析导管的内腔接合和去除血栓。抽吸导管还包括负压源。抽吸导管还包括适于连接负压源和细长柔性轴的近端的连接器。细长柔性轴构造成将碎屑吸入吸入导管。

7. 发明申请

WO2010120671A1 EVERTING DEPLOYMENT SYSTEM AND HANDLE 审中-公开
标题翻译：代表部署制度和手段
公开(公告)号：WO2010120671A1
公开(公告)日：2010-10-21
申请号：PCT/US2010/030696
申请日：2010-04-12
申请人： COOK INCORPORATED , WILLIAM COOK EUROPE APS , PARKER, Fred, T. , HANSEN, Palle, M.
发明人： PARKER, Fred, T. , HANSEN, Palle, M.
IPC分类号： A61F2/84
CPC分类号： A61F2/97 , A61F2/95 , A61F2/966 , A61F2002/9517 , A61F2002/9522 , A61F2250/0039 , A61L29/085
摘要： A stent deployment system, handle, and method of loading of a medical device are provided. The system includes an outer catheter having an inner liner extending past the end of the outer catheter and an inner catheter disposed within the outer catheter. The inner liner is inverted and attached to the inner catheter. Relative movement between the outer and the inner catheters can urge the inner liner to peel away from the medical device. A handle is disposed at the proximal end of the outer catheter, and may include a splitter configured to slice the wall of the tubular member. The handle may also include a rotatable mechanism that can be attached to the tubular member. Rotation of the rotatable mechanism retracts a portion of the tubular member into the handle and winds the sliced portion about the rotatable mechanism.
摘要翻译：提供了支架部署系统，手柄和装载医疗装置的方法。该系统包括具有延伸穿过外导管的端部的内衬套和设置在外导管内的内导管的外导管。内衬被倒置并连接到内导管上。外导管和内导管之间的相对运动可促使内衬从医疗装置剥离。手柄设置在外导管的近端处，并且可以包括被配置为切割管状构件的壁的分流器。手柄还可以包括可连接到管状构件的可旋转机构。可旋转机构的旋转将管状构件的一部分缩回到手柄中并围绕可旋转机构卷绕切片部分。

8. 发明申请

WO2010120620A1 COATED BALLOON CATHETER 审中-公开
标题翻译：涂层气球吸管
公开(公告)号：WO2010120620A1
公开(公告)日：2010-10-21
申请号：PCT/US2010/030355
申请日：2010-04-08
申请人： COOK INCORPORATED , EATON, Elizabeth, A. , SHIRLEY, Gary, B.
发明人： EATON, Elizabeth, A. , SHIRLEY, Gary, B.
IPC分类号： A61M29/02 , A61M25/10
CPC分类号： A61M25/104 , A61M25/1011 , A61M2025/1013 , A61M2025/105 , A61M2025/1075 , A61M2025/1086
摘要： Catheter balloons (10) for delivering a bioactive (260) to a body vessel in a greater amount and/or more quickly are provided, as well as related methods of treatment. The catheter balloon may include a dual balloon assembly at the distal portion (300) of the catheter having an inner balloon (44), an outer balloon (42) with apertures (43) concentrically arrayed around the inner balloon, and a catheter shaft (30) adapted to deliver a carrier (270) through the apertures of the outer balloon. The bioactive is disposed on a portion of at least one of the inner and outer balloon surfaces. Radial outward expansion of the inner balloon urges the outer balloon into contact with the wall of the body vessel. The carrier is introducible within the catheter shaft to pass through the annular lumen (242) between the balloons and through the apertures of the outer balloon. The carrier interacts with the bioactive in order to release a therapeutically effective amount of drug to the wall of the body vessel.
摘要翻译：提供了用于以更大量和/或更快速地将生物活性物质（260）递送至体内血管的导管气球（10）以及相关的治疗方法。导管球囊可以包括在导管的远端部分（300）处的双球囊组件，其具有内球囊（44），具有围绕内球囊同心排列的孔（43）的外球囊（42）和导管轴 30），其适于通过所述外球囊的孔输送载体（270）。生物活性物质设置在内球囊表面和外球囊表面中的至少一个的一部分上。内球囊的径向向外膨胀促使外球囊与体血管的壁接触。载体可以在导管轴内引入，以穿过气囊之间的环形腔（242）并穿过外球囊的孔。载体与生物活性物相互作用，以将治疗有效量的药物释放到人体血管的壁上。

9. 发明申请

WO2010111583A1 STENT GRAFT 审中-公开
公开(公告)号：WO2010111583A1
公开(公告)日：2010-09-30
申请号：PCT/US2010/028814
申请日：2010-03-26
申请人： COOK INCORPORATED , WILLIAM A. COOK AUSTRALIA PTY. LTD. , MED INSTITUTE, INC. , CHUTER, Timothy, A. , HARTLEY, David, Ernest , ROEDER, Blayne, A.
发明人： CHUTER, Timothy, A. , HARTLEY, David, Ernest , ROEDER, Blayne, A.
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/89 , A61F2/91 , A61F2002/061 , A61F2002/065 , A61F2002/075 , A61F2230/0013 , A61F2230/0067 , A61F2250/0039
摘要： A stent graft (10) for endovascular introduction into the pararenal region of the descending aorta, has an elongate tubular body with a proximal portion (12), a distal portion (16) of a diameter less than the proximal portion and a tapered central portion (14). A notional transverse clock face on the tubular body has 12 o'clock at a notional anterior longitudinal datum line and the graft has a scalloped cut out (26) centred at about 12:30 o'clock and a fenestration (28) at about 12:00 o'clock in the proximal portion and first and second fenestration assemblies which can be low profile side arms at about 2: 15 o'clock and about 10:00 o'clock in the tapered central portion. The tapered central portion can have an arcuate side wall (30) so that the tapered portion has an outer face which is concave.
摘要翻译：用于血管内引入下降主动脉的肾上腺区域的支架移植物（10）具有细长管状体，其具有近端部分（12），直径小于近端部分的远端部分（16）和锥形中心部分（14）。管状体上的名义横向钟表面在名义上的前纵向基准线上有12点钟，并且移植物具有以约12:30为中心的扇形切口（26）和大约12°的开窗（28）：近端部分的00点，以及第一和第二开窗组件，其可以是在锥形中心部分的大约2点15点和大约10:00点的低轮廓侧臂。锥形中心部分可以具有弓形侧壁（30），使得锥形部分具有凹面的外表面。

10. 发明申请

WO2010104694A1 HEMOSTASIS VALVE ASSEMBLY 审中-公开
标题翻译： HEMOSTASIS阀组件
公开(公告)号：WO2010104694A1
公开(公告)日：2010-09-16
申请号：PCT/US2010/025836
申请日：2010-03-02
申请人： COOK INCORPORATED , MELSHEIMER, Jeffry, S.
发明人： MELSHEIMER, Jeffry, S.
IPC分类号： A61M39/06
CPC分类号： A61M39/06 , A61M39/0606
摘要： A valve assembly (10) for controlling a flow of fluid includes a housing (30) having a passageway (33 ), and a valve sheath(40) disposed interiorly of the housing, at least substantially along the housing passageway. The valve sheath includes a cylindrical valve body (42) having a pair of generally wedge-shaped voids (5OA, 52A) formed along opposing longitudinal sides of the valve body. Each of the wedge-shaped voids comprises first and second inwardly-directed sides that converge to define a generally linear edge. The edges are disposed along the valve body in a generally diagonal orientation with respect to a longitudinal axis through the valve body. The respective linear edges are structured and aligned in the valve body to meet along a passageway through the valve body interior in a manner to selectively close the valve body interior passageway, and to yield to permit passage of an interventional device therethrough.
摘要翻译：用于控制流体流动的阀组件（10）包括具有通道（33）的壳体（30）和至少基本上沿着壳体通道设置在壳体内部的阀套（40）。阀套包括圆柱形阀体（42），其具有沿阀体的相对的纵向侧面形成的一对大致楔形的空隙（50A，52A）。每个楔形空隙包括第一和第二向内指向的边，其汇合以限定大体上线性的边缘。边缘沿着阀体以相对于穿过阀体的纵向轴线的大致对角线方向设置。相应的线性边缘在阀体中被构造和对准，以便以选择性地关闭阀体内部通道的方式沿着通过阀体内部的通道相遇，并产生以允许介入装置通过其中的通道。

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