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1. 发明申请

WO2019135877A1 SYSTEMS AND METHODS FOR VIDEO-BASED NON-CONTACT TIDAL VOLUME MONITORING 审中-公开
公开(公告)号：WO2019135877A1
公开(公告)日：2019-07-11
申请号：PCT/US2018/065492
申请日：2018-12-13
申请人： COVIDIEN LP
发明人： ADDISON, Paul S. , JACQUEL, Dominique , FOO, David
IPC分类号： A61B5/113 , A61B5/00 , A61B5/091
CPC分类号： A61B5/091 , A61B5/0077 , A61B5/1135 , A61B5/7485 , G06T7/0014 , G06T7/70 , G06T2207/10016 , G06T2207/10028 , G06T2207/30196
摘要： The present invention relates to the field of medical monitoring, and in particular non-contact video monitoring to measure tidal volume of a patient. Systems, methods, and computer readable media are described for determining a region of interest of a patient and monitoring that region of interest to determine tidal volume of the patient. This may be accomplished using a depth sensing camera to monitor a patient and determine how their chest and/or other body parts are moving as the patient breathes. This sensing of movement can be used to determine the tidal volume measurement.

2. 发明申请

WO2019084225A1 A METHOD AND APPARATUS FOR INTERPRETING MULTI-BREATH NITROGEN WASHOUT DATA 审中-公开
公开(公告)号：WO2019084225A1
公开(公告)日：2019-05-02
申请号：PCT/US2018/057438
申请日：2018-10-25
申请人： THE UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE
发明人： BATES, Jason, T.
IPC分类号： A61B5/08 , A61B5/093
CPC分类号： A61B5/083 , A61B5/091
摘要： A novel method and apparatus for analyzing multi-breath nitrogen washout (MBNW) data from a lung is provided. The novel method includes fitting multi-compartment lung model, having five free parameters, to an exhaled nitrogen concentration profile over the entire duration of expiration for each breath from the lung. The five free parameters include 1) functional residual capacity, 2) dead space volume, 3) the standard deviation of the rate of change of fractional contribution to expired flow from each lung region as a function of lung volume, 4) the intrinsic slope of Phase-Ill due to acinar asymmetry, and 5) the coefficient of variation of regional specific ventilation.

3. 发明申请

WO2018042152A1 METHOD AND APPARATUS FOR QUANTIFYING LUNG FUNCTION 审中-公开
标题翻译：用于量化肺功能的方法和设备
公开(公告)号：WO2018042152A1
公开(公告)日：2018-03-08
申请号：PCT/GB2017/052397
申请日：2017-08-15
申请人： OXFORD UNIVERSITY INNOVATION LIMITED
发明人： ROBBINS, Peter Alistair , HANCOCK, Gus , RITCHIE, Grant , MOUNTAIN, James , O'NEILL, David , WHITELEY, Jonathan , CIAFFONI, Luca , COUPER, John
IPC分类号： A61B5/08 , A61B5/091 , G06F19/00 , A61B5/097 , A61B5/00
CPC分类号： A61B5/091 , A61B5/0075 , A61B5/082 , A61B5/0833 , A61B5/0836 , A61B5/085 , A61B5/087 , A61B5/097 , G16H20/40 , G16H50/50
摘要： A method and apparatus for non-invasive assessment of lung inhomogeneity by accurate high temporal resolution measurement of respiratory gas flows at the mouth during steady state breathing and inert gas wash-in or wash-out and using these measurements to fit a mathematical model of the inhomogeneous lung. The model of the lung is based on modelling the lung as plural alveolar compartments each having an identical volume at functional residual capacity, but varying in its fractional share of total lung compliance, total pulmonary vascular conductance and total anatomical deadspace. A bivariate log- normal distribution of the lung compliance and pulmonary vascular conductance is used, together with a normal distribution of deadspace fraction. The model is fitted to the measurements using non-linear regression and the distribution of ventilation: perfusion ratios, lung compliance: volume ratios, lung vascular conductance: volume ratios and lung deadspace: volume ratios obtained from the fitted model are indicative of the airway condition and thus lung function of the subject.
摘要翻译：通过在稳定状态呼吸和惰性气体洗入或洗出期间在口腔处的呼吸气体流量的精确高时间分辨率测量来非侵入性评估肺不均匀性并使用这些方法和设备测量来拟合不均匀肺的数学模型。肺模型基于将肺模拟为多个肺泡隔室，每个肺泡隔室在功能残留容量上具有相同的体积，但其总体肺顺应性，总肺血管传导性和总解剖死腔的分数份额不同。使用肺顺应性和肺血管传导的双变量对数正态分布，以及死体积分数的正态分布。使用非线性回归和通气分布将模型拟合成测量值：灌注比率，肺顺应性：体积比，肺血管传导率：体积比和肺死体积：从拟合模型获得的体积比指示气道条件并因此改变受试者的肺功能。

4. 发明申请

WO2017100188A3 METHODS AND APPARATUSES FOR ASSESSMENT AND MANAGEMENT OF HEMODYNAMIC STATUS 审中-公开
标题翻译：用于评估和管理血液动力状态的方法和设备
公开(公告)号：WO2017100188A3
公开(公告)日：2017-07-27
申请号：PCT/US2016065140
申请日：2016-12-06
申请人： MEDICI TECH LLC
发明人： ROBINSON MARK RIES , ALLEN ELENA A
IPC分类号： A61B5/024 , A61B5/0402 , A61B5/107
CPC分类号： A61B5/0205 , A61B5/02125 , A61B5/02416 , A61B5/029 , A61B5/0452 , A61B5/091 , A61B5/1116 , A61B5/113 , A61B5/4561
摘要： Embodiments of the present invention provide reliable, convenient, and cost-effective methods and apparatuses to determine the hemodynamic status of the patent. The methods and apparatuses provide for the noninvasive determine of hemodynamic status by using systematic perturbations of venous return or trend observation over time. Embodiments do not require invasive pressure monitoring or the use of ventilator but instead can be an entirely noninvasive system.
摘要翻译：本发明的实施例提供可靠，方便且成本有效的方法和装置以确定专利的血液动力学状态。该方法和装置通过使用随时间的静脉回流或趋势观察的系统扰动来提供对血液动力学状态的无创确定。实施例不需要有创压力监测或呼吸机的使用，而是可以是完全无创的系统。

5. 发明申请

WO2017100188A2 METHODS AND APPARATUSES FOR ASSESSMENT AND MANAGEMENT OF HEMODYNAMIC STATUS 审中-公开
标题翻译：用于评估和管理血液动力状态的方法和设备
公开(公告)号：WO2017100188A2
公开(公告)日：2017-06-15
申请号：PCT/US2016/065140
申请日：2016-12-06
申请人： MEDICI TECHNOLOGIES, LLC
发明人： ROBINSON, Mark, Ries , ALLEN, Elena, A.
IPC分类号： A61B5/0205
CPC分类号： A61B5/0205 , A61B5/02125 , A61B5/02416 , A61B5/029 , A61B5/0452 , A61B5/091 , A61B5/1116 , A61B5/113 , A61B5/4561
摘要： Embodiments of the present invention provide reliable, convenient, and cost-effective methods and apparatuses to determine the hemodynamic status of the patent. The methods and apparatuses provide for the noninvasive determine of hemodynamic status by using systematic perturbations of venous return or trend observation over time. Embodiments do not require invasive pressure monitoring or the use of ventilator but instead can be an entirely noninvasive system.
摘要翻译：本发明的实施例提供可靠，方便和成本有效的方法和装置来确定专利的血液动力学状态。该方法和装置通过使用随时间的静脉回流或趋势观察的系统扰动来提供对血液动力学状态的无创确定。实施例不需要有创压力监测或使用呼吸机，而是可以是完全无创的系统。

6. 发明申请

WO2017055959A1 SIMULTANEOUS ESTIMATION OF RESPIRATORY MECHANICS AND PATIENT EFFORT VIA PARAMETRIC OPTIMIZATION 审中-公开
标题翻译：通过参数优化同时估计呼吸机制和患者功效
公开(公告)号：WO2017055959A1
公开(公告)日：2017-04-06
申请号：PCT/IB2016/055568
申请日：2016-09-18
申请人： KONINKLIJKE PHILIPS N.V.
发明人： VICARIO, Francesco , ALBANESE, Antonio , WANG, Dong , KARAMOLEGKOS, Nikolaos , CHBAT, Nicolas Wadih
IPC分类号： G06F17/12 , G06F17/17 , G06F19/00 , A61B5/087 , A61B5/03 , A61B5/085 , A61B5/00 , A61B5/091
CPC分类号： A61B5/087 , A61B5/038 , A61B5/085 , A61B5/091 , A61B5/682 , A61B2505/03 , G06F19/00 , G06F19/3481 , G16H50/50
摘要： Respiratory variables are estimated on a per-breath basis from airway pressure and flow data acquired by airway pressure and flow sensors (20, 22). A breath detector (28) detects a breath interval. A per-breath respiratory variables estimator (30) fits the airway pressure and flow data over the detected breath interval to an equation of motion of the lungs relating airway pressure, airway flow, and a single-breath parameterized respiratory muscle pressure profile (40, 42) to generate optimized parameter values for the single-breath parameterized respiratory muscle pressure profile. Respiratory muscle pressure is estimated as a function of time over the detected breath interval as the single-breath parameterized respiratory muscle pressure profile with the optimized parameter values, and may for example be displayed as a trend line on a display device (26, 36) or integrated (32) to generate Work of Breathing (WoB) for use in adjusting settings of a ventilator (10).
摘要翻译：根据气道压力和气道压力和流量传感器获得的流量数据，呼吸变量按每呼吸估计（20,22）。呼吸检测器（28）检测呼吸间隔。每呼吸呼吸变量估计器（30）将检测到的呼吸间隔中的气道压力和流量数据适合于将气道压力，气道流量和单呼吸参数化呼吸肌肉压力分布相关联的肺的运动方程（40， 42）以产生用于单呼吸参数化呼吸肌压力分布的优化参数值。作为具有优化的参数值的单呼吸参数化呼吸肌力压力分布，在所检测到的呼吸间隔上估计呼吸肌肉压力作为时间的函数，并且可以例如在显示装置（26,36）上显示为趋势线，或集成（32）以产生呼吸工作（WoB），以用于调节呼吸机（10）的设置。

7. 发明申请

WO2016186724A1 SYSTEMS AND METHODS FOR WEARABLE SENSOR TECHNIQUE 审中-公开
标题翻译：用于传感器技术的系统和方法
公开(公告)号：WO2016186724A1
公开(公告)日：2016-11-24
申请号：PCT/US2016/023757
申请日：2016-03-23
申请人： AMIIGO, INC.
发明人： CARTER, Abraham , SCOTT, David , AZARNASAB, Ehsan
IPC分类号： A61B5/02 , H04M1/02 , G06Q50/22
CPC分类号： A61B5/7289 , A61B5/0022 , A61B5/0024 , A61B5/02 , A61B5/02416 , A61B5/03 , A61B5/0816 , A61B5/091 , A61B5/1118 , A61B5/14532 , A61B5/14551 , A61B5/4806 , A61B5/4809 , A61B5/4812 , A61B5/4815 , A61B5/6824 , A61B5/6829 , A61B5/7246 , A61B5/742 , A61B5/746 , A61B2562/0219 , G06F19/00 , G06Q50/22 , H04M1/7253
摘要： Aspects of the present invention relate to analysis of physiological data sequences and activity data recorded while a user participates in various activities. Some aspects relate to alert or messaging system and methods whereby messages are automatically generated when a condition in the physiological or activity data is satisfied. Messages may be automatically formatted with physiological and/or activity data as well as other fields and content. Each message condition may be related to a unique recipient list and message content template.
摘要翻译：本发明的方面涉及在用户参与各种活动时记录的生理数据序列和活动数据的分析。一些方面涉及警报或消息传递系统和方法，从而当满足生理或活动数据中的条件时自动生成消息。消息可以使用生理和/或活动数据以及其他字段和内容自动格式化。每个消息条件可以与唯一的接收者列表和消息内容模板相关。

8. 发明申请

WO2016164623A1 AMBULATORY EXTENDED-WEAR ELECTROCARDIOGRAPHY AND SYNCOPE SENSOR MONITOR 审中-公开
标题翻译：增强型电磁兼容传感器监视器
公开(公告)号：WO2016164623A1
公开(公告)日：2016-10-13
申请号：PCT/US2016/026502
申请日：2016-04-07
申请人： BARDY DIAGNOSTICS, INC.
发明人： FELIX, Jason , BISHAY, Jon Mikalson , BARDY, Gust H.
IPC分类号： A61B5/0432 , A61B5/11 , A61B5/00 , A61B5/04 , G01N27/30
CPC分类号： A61B5/04085 , A61B5/0006 , A61B5/0022 , A61B5/01 , A61B5/02055 , A61B5/021 , A61B5/04017 , A61B5/04087 , A61B5/04325 , A61B5/0452 , A61B5/04525 , A61B5/0816 , A61B5/087 , A61B5/091 , A61B5/1116 , A61B5/1117 , A61B5/1118 , A61B5/14532 , A61B5/14542 , A61B5/14551 , A61B5/4809 , A61B5/6801 , A61B5/6823 , A61B5/6833 , A61B5/7455 , A61B2505/07 , A61B2560/0271 , A61B2560/0412 , A61B2560/045 , A61B2562/0219 , A61B2562/164 , G01N27/307
摘要： Physiological monitoring can be provided through a syncope sensor (64, 66) embedded into an electrocardiography monitor (12), which correlates syncope events and electrocardiographic data. Physiological monitoring can be provided through a lightweight wearable monitor (12) that includes two components: a flexible extended-wear electrode patch (15) and a reusable monitor recorder (14) that removably snaps into a receptacle (25) on the electrode patch (15). The wearable monitor (12) sits centrally on the patient's sternal midline (16) and includes a unique narrow "hourglass"-like shape, significantly improving the ability of the monitor to cutaneously sense cardiac electrical potential signals, particularly the P-wave and QRS interval signals. The electrocardiographic electrodes (38, 39) on the electrode patch (15) are tailored for axial positioning along the midline (16) of the sternum (13) to capture action potential propagation in an orientation that corresponds to the aVF lead in a conventional 12-lead electrocardiogram, which senses positive P-waves (271).
摘要翻译：可以通过嵌入心电图监视器（12）中的晕厥传感器（64,66）来提供生理监测，其将晕厥事件和心电图数据相关联。可以通过包括两个部件的轻量级可穿戴式监视器（12）来提供生理监测：柔性延伸耐磨电极贴片（15）和可重复使用的监视器记录器（14），其可拆卸地卡入电极贴片上的插座（25） 15）。可穿戴式监视器（12）位于患者胸骨中线（16）的中心，并且包括独特的窄的“沙漏”状形状，显着提高了监护仪的心脏电位信号特别是P波和QRS的能力间隔信号电极贴片（15）上的心电图电极（38,39）被定制成沿着胸骨（13）的中线（16）进行轴向定位，以捕获在常规12中对应于aVF引线的取向中的动作电位传播 - 心电图检测正P波（271）。

9. 发明申请

WO2016157106A1 METHODS AND APPARATUS FOR OXYGENATION AND/OR CO2 REMOVAL 审中-公开
标题翻译：氧化和/或二氧化碳去除的方法和装置
公开(公告)号：WO2016157106A1
公开(公告)日：2016-10-06
申请号：PCT/IB2016/051820
申请日：2016-03-31
申请人： FISHER & PAYKEL HEALTHCARE LIMITED
发明人： OLDFIELD, Samantha Dale , ASSI, Milanjot Singh , KEOGH, Geraldine , SPENCE, Callum James Thomas , BARRACLOUGH, Michael , PAYTON, Matthew Jon , HERMEZ, Laith Adeeb , BARNES, Thomas Heinrich , WHITE, Craig Karl , EVANS, Alicia Jerram Hunter
IPC分类号： A61M16/00 , A61B5/087 , A61B5/091
CPC分类号： A61M16/0069 , A61B5/0205 , A61B5/024 , A61B5/087 , A61B5/091 , A61B5/14542 , A61M16/0006 , A61M16/0096 , A61M16/024 , A61M16/0666 , A61M16/107 , A61M16/109 , A61M16/12 , A61M16/16 , A61M16/161 , A61M16/202 , A61M16/203 , A61M16/209 , A61M2016/0027 , A61M2016/0033 , A61M2016/1025 , A61M2202/0208 , A61M2202/0225 , A61M2205/3303 , A61M2205/3334 , A61M2205/3368 , A61M2205/502 , A61M2205/52 , A61M2230/04 , A61M2230/06 , A61M2230/10 , A61M2230/202 , A61M2230/205 , A61M2230/42 , A61M2230/432 , A61M2230/60 , A61M2230/63 , A61M2230/005
摘要： Described is an apparatus for oxygenation and/or CO2 clearance of a patient, comprising: a flow source or a connection for a flow source for providing a gas flow, a gas flow modulator, a controller to control the gas flow, wherein the controller is operable to: receive input relating to heart activity and/or trachea gas flow of the patient, and control the gas flow modulator to provide a varying gas flow with one or more oscillating components with a frequency or frequencies based on the heart activity and/or trachea flow of the patient.
摘要翻译：描述了一种用于患者的氧合和/或CO 2清除的装置，包括：流源或用于提供气流的流动源的连接，气流调节器，用于控制气流的控制器，其中控制器是可操作地：接收与患者的心脏活动和/或气管气体流量有关的输入，并且控制气体流量调节器以提供具有基于心脏活动的频率或频率的一个或多个振荡组件的变化气流和/或气管气流病人。

10. 发明申请

WO2016153358A2 VENTILATION MEASUREMENT DEVICES, METHODS AND COMPUTER PROGRAM PRODUCT 审中-公开
标题翻译：通气测量装置，方法和计算机程序产品
公开(公告)号：WO2016153358A2
公开(公告)日：2016-09-29
申请号：PCT/NO2016/050054
申请日：2016-03-18
申请人： SHARP SOFTWARE AS
发明人： LAUGSTØL, Arne
IPC分类号： A61B5/113
CPC分类号： A61B5/6831 , A61B5/0004 , A61B5/0803 , A61B5/0816 , A61B5/087 , A61B5/091 , A61B5/1135 , A61B5/6823 , A61B5/7278 , A61B5/742 , A61B2562/0261 , G01B7/16
摘要： A ventilation measurement device includes a fastening mechanism (8) capable of permanently or detachably fastening the ventilation measurement device (1) to a belt (2) which can be worn around a person's chest. The device includes a substrate (4, 4', 4") coupled to the fastening mechanism (8) and capable of receiving tensional forces transmitted from the flexible belt (2) through the fastening mechanism (8). A strain gauge (3) mounted on said substrate and configured to output a signal with a functional relationship with said tensional forces delivers measurement signals to a controller unit configured to receive and process the signal to produce processed data from the strain gauge signal and to control a transmitter configured to transmit processed data to an external receiver.
摘要翻译：通风测量装置包括紧固机构（8），该紧固机构能够将通风测量装置（1）永久地或可拆卸地紧固到可佩戴在人的胸部周围的带（2）上。该装置包括联接到紧固机构（8）并且能够接收通过紧固机构（8）从柔性带（2）传递的张力的基底（4,4'，4“）。安装在所述衬底上并被配置为输出具有与所述张力的函数关系的信号的应变仪（3）将测量信号传递到控制器单元，所述控制器单元被配置为接收并处理信号以从应变仪信号产生处理后的数据并且控制配置为将处理后的数据发送到外部接收器的发射器。

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