专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

61. 发明授权

US07662568B2 Immunoliposome-nucleic acid amplification (ILNAA) assay 失效
标题翻译：免疫脂质体 - 核酸扩增（ILNAA）检测
公开(公告)号：US07662568B2
公开(公告)日：2010-02-16
申请号：US12399060
申请日：2009-03-06
申请人： Timothy J. O'Leary , Jeffrey T. Mason
发明人： Timothy J. O'Leary , Jeffrey T. Mason
IPC分类号： C12Q1/68
CPC分类号： A61K9/127 , C12Q1/6806 , C12Q2563/161
摘要： Immunoliposomes and use thereof in highly specific and sensitive nucleic acid amplification assays relying on amplification of specific nucleic acid sequences released from encapsulation within a liposome after a receptor on the liposome couples with a targeted analyte/antigen immobilized on a select surface. The immunoliposome nucleic acid amplification assay permits both quantitative and qualitative analyte detection.
摘要翻译：免疫脂质体及其在高度特异性和灵敏的核酸扩增测定中的应用，其依赖于在脂质体上的受体之后从包封在脂质体内释放的特异性核酸序列的扩增与固定在选择表面上的靶向分析物/抗原相结合。免疫脂质体核酸扩增测定允许定量和定性分析物检测。

62. 发明授权

US07582430B2 Immunoliposome-nucleic acid amplification (ILNAA) assay 失效
标题翻译：免疫脂质体 - 核酸扩增（ILNAA）检测
公开(公告)号：US07582430B2
公开(公告)日：2009-09-01
申请号：US10759099
申请日：2004-01-20
申请人： Timothy J. O'Leary , Jeffrey T. Mason
发明人： Timothy J. O'Leary , Jeffrey T. Mason
IPC分类号： C12Q1/68
CPC分类号： A61K9/127 , C12Q1/6806 , C12Q2563/161
摘要： Immunoliposomes and use thereof in highly specific and sensitive nucleic acid amplification assays relying on amplification of specific nucleic acid sequences released from encapsulation within a liposome after a receptor on the liposome couples with a targeted analyte/antigen immobilized on a select surface. The immunoliposome nucleic acid amplification assay permits both quantitative and qualitative analyte detection.
摘要翻译：免疫脂质体及其在高度特异性和灵敏的核酸扩增测定中的应用，其依赖于在脂质体上的受体之后从包封在脂质体内释放的特异性核酸序列的扩增与固定在选择表面上的靶向分析物/抗原相结合。免疫脂质体核酸扩增测定允许定量和定性分析物检测。

63. 发明授权

US07309333B2 Medication delivery system having selective automated or manual discharge 失效
标题翻译：具有选择性自动或手动放电的药物输送系统
公开(公告)号：US07309333B2
公开(公告)日：2007-12-18
申请号：US10933619
申请日：2004-09-02
申请人： Jeffrey T. Mason
发明人： Jeffrey T. Mason
IPC分类号： A61M31/00
CPC分类号： A61M5/1454 , A61M5/1411 , A61M5/165 , A61M2005/1405
摘要： A portable medication delivery system enables a patient to elect slow continuous auto-administration or rapid bolus self-administration of a fluid medication. The medication delivery system has an infusion pump, which includes a fluid storage chamber and a spring-driven piston positioned in the fluid storage chamber. The fluid storage chamber is initially charged with the medication and the infusion pump automatically delivers a continuous dosage of the medication at a first flow rate over a long time from the fluid storage chamber to a treatment site in the patient. A bolus injector is positioned in series or in parallel with the infusion pump and is charged with a bolus dosage of the treatment fluid from the fluid storage chamber for alternate manual self-injection of the medication into the treatment site at a higher second flow rate for a short time. The infusion pump flowpath includes a drip chamber having an in-line flow restriction, which converts a continuous flow stream from the fluid storage chamber to a drip stream. A sight window in the drip chamber permits the user to visually confirm the flow of medication through the infusion pump.
摘要翻译：便携式药物输送系统使得患者能够选择缓慢的连续自动给药或快速推注流体药物的自我施用。药物输送系统具有输液泵，其包括流体储存室和定位在流体储存室中的弹簧驱动的活塞。液体储存室最初被充满药物，并且输液泵以长时间的第一流速自动地将药物的连续剂量从液体储存室输送到患者的治疗部位。推注注射器与输注泵串联或并联放置，并且从流体存储室中以大剂量的治疗流体装入，用于以更高的第二流速将药物交替地手动自我注射到治疗部位，用于很短的时间。输液泵流路包括具有直列流动限制的滴水室，其将来自流体储存室的连续流动流转换成滴流。滴液室中的视窗允许使用者通过输液泵目视确认药物的流动。

64. 发明授权

US07163521B2 Integrated infusion and aspiration system and method 失效
标题翻译：一体化输液和吸气系统及方法
公开(公告)号：US07163521B2
公开(公告)日：2007-01-16
申请号：US10896515
申请日：2004-07-22
申请人： E. Marlowe Goble , Mark E. Howard , Jeffrey T. Mason , T. Wade Fallin
发明人： E. Marlowe Goble , Mark E. Howard , Jeffrey T. Mason , T. Wade Fallin
IPC分类号： A61M1/00
CPC分类号： A61M1/0023 , A61M1/0037 , A61M1/0058 , A61M25/0021 , A61M25/007 , A61M27/00 , A61M2025/0004 , A61M2025/0037 , A61M2025/0039 , A61M2025/018
摘要： An integrated infusion and aspiration system includes a flow control system and a catheter assembly. The catheter assembly includes an infusion catheter and an aspiration catheter, each having ports located at the distal end of thereof. The distal ends of the catheters are separated so that the aspiration catheter ports can be positioned on an opposing side of a surgical wound site from the infusion catheter ports. Methods of operation of the integrated infusion and aspiration system provide for uninterrupted aspiration with concurrent controlled delivery of an infusion solution such that the infusion solution is substantially evenly dispersed of over the wound site.
摘要翻译：集成输液和抽吸系统包括流量控制系统和导管组件。导管组件包括输注导管和抽吸导管，每个具有位于其远端的端口。导管的远端被分离，使得吸引导管端口可以位于外科伤口部位与输注导管端口相对的一侧。一体化输注和抽吸系统的操作方法提供不间断的抽吸，同时控制输送输液，使得输注溶液基本均匀地分散在伤口部位上方。

65. 外观设计

USD486870S1 Continuous passive motion device for a shoulder or elbow 失效
标题翻译：用于肩部或肘部的连续被动运动装置
公开(公告)号：USD486870S1
公开(公告)日：2004-02-17
申请号：US29170254
申请日：2002-11-01
申请人： Jeffrey T. Mason
设计人： Jeffrey T. Mason

66. 发明授权

US06270481B1 Patient-controlled medication delivery system 失效
标题翻译：患者控制的药物输送系统
公开(公告)号：US06270481B1
公开(公告)日：2001-08-07
申请号：US09334856
申请日：1999-06-16
申请人： Bradley R. Mason , Jeffrey T. Mason
发明人： Bradley R. Mason , Jeffrey T. Mason
IPC分类号： A61M500
CPC分类号： A61M5/1424 , A61M5/14244 , A61M5/1456
摘要： A portable, patient-controlled medication delivery system includes an infusion pump, a catheter assembly and an extension tubing set. The infusion pump retains a treatment fluid and provides a drive mechanism for delivering the treatment fluid to a patient. The catheter assembly has a medicine catheter which penetrates directly into the treatment site of the patient and the extension tubing set has an extension tube which connects the medicine catheter and infusion pump. The infusion pump includes a fluid reservoir, a dosage chamber, and a displacement piston displacable within the dosage chamber. An elastic member is also positioned in the infusion pump to exert a displacement force on the displacement piston. The elastic member is alternately transitionable between a more stressed position and a less stressed position. The elastic member elastically displaces the displacement piston in a first direction to expand the dosage chamber and draw the treatment fluid from the fluid reservoir into the dosage chamber when the elastic member transitions from the more stressed position to the less stressed position. The displacement piston is manually displaced in a second direction to contract the dosage chamber and discharge the treatment fluid from the dosage chamber to the treatment site when the elastic member transitions from the less stressed position to the more stressed position.
摘要翻译：便携式，患者控制的药物输送系统包括输液泵，导管组件和延伸管组。输注泵保持处理流体并提供用于将治疗流体递送到患者的驱动机构。导管组件具有直接穿入患者治疗部位的药导管，延伸管组具有连接药导管和输液泵的延伸管。输注泵包括流体储存器，剂量室和位于剂量室内的置换活塞。弹性构件也定位在输注泵中以在位移活塞上施加位移力。弹性构件在更受应力的位置和较小的应力位置之间可交替地转换。当弹性构件从较受应力的位置转变到较小的应力位置时，弹性构件沿着第一方向弹性移位位移活塞以扩展剂量室并将处理流体从流体储存器抽出到剂量室中。当弹性构件从较小的应力位置转变到较受应力的位置时，位移活塞在第二方向上手动地移位以收缩剂量室并将处理流体从剂量室排出到治疗部位。

67. 发明授权

US06176869B1 Fluid drive mechanism for a therapeutic treatment system 有权
标题翻译：用于治疗治疗系统的流体驱动机构
公开(公告)号：US06176869B1
公开(公告)日：2001-01-23
申请号：US09257796
申请日：1999-02-25
申请人： Jeffrey T. Mason , Richard W. Royer
发明人： Jeffrey T. Mason , Richard W. Royer
IPC分类号： A61F700
CPC分类号： A61F7/02 , A61F2007/0042 , A61F2007/0054
摘要： A system for therapeutically treating a desired region of a patient's body by circulating a nonambient temperature treatment fluid through a pad positioned on the treatment region. The system is provided with a fluid drive mechanism including a flow control assembly and a pump for delivering a drive fluid to the flow control assembly. The flow control assembly houses a pressurizing chamber having a drive fluid inlet and outlet and a treatment fluid inlet and outlet. A drive fluid outlet valve and treatment fluid inlet valve are provided to selectively restrict flow through the drive fluid outlet and treatment fluid inlet, respectively. Operation of the flow control assembly initiates with both the drive fluid outlet valve and treatment fluid inlet valve in an open position, enabling the pressurizing chamber to receive fresh treatment fluid in a receiving mode. When the drive pressure in the pressurizing chamber reaches a predetermined pressure value correlated to the volume of fresh treatment fluid in the pressurizing chamber, the flow control assembly automatically transitions to a discharging mode, wherein both the drive fluid outlet valve and the treatment fluid inlet valve assume a closed position. As a result the fresh treatment fluid is driven from the pressurizing chamber into the pad where it displaces treatment fluid residing therein.
摘要翻译：一种用于通过使非外界温度处理流体循环通过位于治疗区域上的垫来治疗性地治疗患者身体的所需区域的系统。该系统设置有流体驱动机构，其包括流量控制组件和用于将驱动流体输送到流量控制组件的泵。流量控制组件容纳具有驱动流体入口和出口以及处理流体入口和出口的加压室。提供驱动流体出口阀和处理流体入口阀以分别选择性地限制通过驱动流体出口和处理流体入口的流动。流量控制组件的操作开始于驱动流体出口阀和处理流体入口阀处于打开位置，使得加压室能够以接收模式接收新鲜的处理流体。当加压室中的驱动压力达到与加压室中的新鲜处理流体的体积相关的预定压力值时，流量控制组件自动转变到排出模式，其中驱动流体出口阀和处理流体入口阀假设关闭位置。结果，新鲜的处理流体从加压室驱动到垫中，其中置换其中存在的处理流体。

68. 发明授权

US5827208A Hinge for an orthopedic brace having a selectively positionable stop to limit rotation 失效
标题翻译：用于矫形支架的铰链具有可选择的定位止挡以限制旋转
公开(公告)号：US5827208A
公开(公告)日：1998-10-27
申请号：US886608
申请日：1997-07-01
申请人： Bradley R. Mason , Jeffrey T. Mason
发明人： Bradley R. Mason , Jeffrey T. Mason
IPC分类号： A61F5/01 , A61F5/00
CPC分类号： A61F5/0125 , A61F2005/0167
摘要： A hinge is provided for an orthopedic brace having an adjustable range of rotation. The hinge includes an outer member and an inner member that are rotatably connected in parallel alignment to one another. The peripheral edge of the outer member has a plurality of rotation limiting notches formed therein and the peripheral edge of the inner member has a rotation limiting face formed therein that is selectively alignable with one of the rotation limiting notches. Each of the peripheral edges also has a locking notch formed therein that is selectively alignable with the other. A rotation limiting stop is provided at the peripheral edge of the inner and outer members that is selectively positionable in one of the rotation limiting notches to define an adjustable range of rotation during a rotation mode of hinge operation. Rotation of the inner member is limited when the rotation limiting face engages the rotation limiting stop positioned in the selected notch. Alternatively, the rotation limiting stop is selectively positionable in the locking notches to lock the hinge against rotation in a locked mode of hinge operation. The hinge also includes a stop retainer, which retains the rotation limiting stop in the selected rotation limiting notch or locking notch during a rotation or locking mode of hinge operation, respectively, and which enables repositioning of the rotation limiting stop in an alternately selected rotation limiting notch during an adjustment mode of operation.
摘要翻译：为具有可调节旋转范围的矫形支架提供铰链。铰链包括彼此平行对准地可旋转地连接的外部构件和内部构件。外部构件的外围边缘具有形成在其中的多个旋转限制凹口，并且内部构件的周缘具有形成在其中的旋转限制面，其可选择性地与旋转限制凹口之一对准。每个外围边缘还具有形成在其中的锁定凹口，其可选择性地与另一个对准。旋转限制止挡设置在内部和外部构件的外围边缘处，该外部构件可选择性地定位在旋转限制凹口之一中，以在铰链操作的旋转模式期间限定可调节的旋转范围。当旋转限制面接合位于所选择的凹口中的旋转限制止动件时，内部构件的旋转受到限制。或者，旋转限制止动件可选择性地定位在锁定凹口中，以在铰链操作的锁定模式下锁定铰链以防旋转。铰链还包括止动保持器，其分别在铰链操作的旋转或锁定模式期间将旋转限制止动件保持在所选择的旋转限制凹口或锁定凹口中，并且能够使旋转限制止动件重新定位在交替选择的旋转限制在调整操作模式期间切口。

69. 发明授权

US5807294A Adjustable hinge assembly for an osteoarthritic knee brace 失效
标题翻译：用于骨关节炎膝盖支架的可调铰链组件
公开(公告)号：US5807294A
公开(公告)日：1998-09-15
申请号：US820876
申请日：1997-03-21
申请人： Patrick W. Cawley , Jeffrey T. Mason
发明人： Patrick W. Cawley , Jeffrey T. Mason
IPC分类号： A61F5/01 , A61F5/32
CPC分类号： A61F5/0123 , A61F2005/0139 , A61F2005/0174
摘要： A hinge assembly is provided for an orthopedic knee brace that pivotally couples a first rotation member and a second rotation member. The hinge assembly includes a pad assembly, a hinge, and first and second adjustment members enabling adjustment of the normal force applied by the hinge assembly to the knee joint for the effective treatment of osteoarthritis. The hinge includes an end of the first rotation member, an end of the second rotation member, first and second hinge plates positioned on opposite sides of the ends, and first and second hinge fasteners. The first and second hinge fasteners each has a bore therethrough that is internally threaded. The first hinge fastener rotatably connects the end of the first rotation member to the first and second hinge plates and the second hinge fastener rotatably connects the end of the second rotation member to the first and second hinge plates. The first adjustment member has external threads that are received by the internal threads of the first hinge fastener to telescopically couple the first adjustment member to the first hinge fastener. The second adjustment member likewise has external threads that are received by the internal threads of the second hinge fastener to telescopically couple the second adjustment member to the second hinge fastener. Both the first and second adjustment members have ends that are substantially fixedly coupled to the pad holder. As a result selective displacement of the pad assembly toward or away from the hinge is enabled when the user selectively displaces the first and second adjustment members through the first and second bores of the first and second hinge fasteners.
摘要翻译：提供了一种用于可旋转地联接第一旋转构件和第二旋转构件的矫形膝盖支架的铰链组件。铰链组件包括衬垫组件，铰链以及第一和第二调节构件，其能够调节由铰链组件施加到膝关节的法向力，以有效治疗骨关节炎。铰链包括第一旋转构件的端部，第二旋转构件的端部，位于端部的相对侧上的第一和第二铰链板以及第一和第二铰链紧固件。第一和第二铰链紧固件各自具有穿过其中的内螺纹的孔。第一铰链紧固件将第一旋转构件的端部可旋转地连接到第一和第二铰链板，并且第二铰链紧固件将第二旋转构件的端部可旋转地连接到第一和第二铰链板。第一调节构件具有由第一铰链紧固件的内螺纹接收的外螺纹，以将第一调节构件可伸缩地联接到第一铰链紧固件。第二调节构件同样具有由第二铰链紧固件的内螺纹接收的外螺纹，以将第二调节构件可伸缩地联接到第二铰链紧固件。第一调节构件和第二调节构件都具有基本上固定地联接到衬垫保持器的端部。因此，当使用者通过第一和第二铰链紧固件的第一和第二孔选择性地移动第一和第二调节构件时，能够使垫组件朝向或远离铰链的选择性移位。

70. 外观设计

USD383848S Cold therapy pad 失效
公开(公告)号：USD383848S
公开(公告)日：1997-09-16
申请号：US055426
申请日：1996-06-04
申请人： Bradley R. Mason , Jeffrey T. Mason , Suechyi J. Kuan
设计人： Bradley R. Mason , Jeffrey T. Mason , Suechyi J. Kuan

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式