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1. 发明授权

US08529884B2 Cosmid DNA constructs and methods of making and using same 有权
标题翻译：粘粒DNA构建体及其制备和使用方法
公开(公告)号：US08529884B2
公开(公告)日：2013-09-10
申请号：US10168694
申请日：2000-12-22
申请人： David B. Weiner , Jeong-Im Sin , Donghui Zhang
发明人： David B. Weiner , Jeong-Im Sin , Donghui Zhang
IPC分类号： A01N63/00 , A01N43/04
CPC分类号： A61K39/00 , A61K39/12 , A61K39/245 , A61K48/00 , A61K2039/53 , A61K2039/54 , C12N2710/16634
摘要： Methods of inducing immune responses in individuals against a pathogen are disclosed. Methods of treating individuals susceptible to or suffering from a disease associated with a genetic defect which results in the non-production or under production of a protein or the production of a non-functioning or partially functioning protein are disclosed. Methods of delivering a protein to an individual are disclosed. Pharmaceutical compositions that comprise cosmids are disclosed.
摘要翻译：公开了在针对病原体的个体中诱导免疫应答的方法。公开了治疗导致非生产或正在产生蛋白质或产生不起作用或部分功能的蛋白质的遗传缺陷相关疾病或患有疾病的个体的方法。公开了向个体递送蛋白质的方法。公开了包含粘粒的药物组合物。

2. 发明申请

US20050276480A1 Handwritten input for Asian languages 审中-公开
标题翻译：亚洲语言的手写输入
公开(公告)号：US20050276480A1
公开(公告)日：2005-12-15
申请号：US10870535
申请日：2004-06-18
申请人： Dong Li , Donghui Zhang , Yong Zhang
发明人： Dong Li , Donghui Zhang , Yong Zhang
IPC分类号： G06F3/01 , G06K9/18 , G09G5/00
CPC分类号： G06F3/018
摘要： A system and process for helping users enter information in an Asian language is described. In some aspects, input for simplified Chinese and other languages is described with respect to handwritten input.
摘要翻译：描述了一种帮助用户输入亚洲语言信息的系统和过程。在一些方面，针对手写输入描述了简体中文和其他语言的输入。

3. 发明申请

US20050201986A1 Cell targeting compositions and methods of using the same 审中-公开
标题翻译：细胞靶向组合物及其使用方法
公开(公告)号：US20050201986A1
公开(公告)日：2005-09-15
申请号：US11123600
申请日：2005-05-06
申请人： David Weiner , Jong Kim , Donghui Zhang
发明人： David Weiner , Jong Kim , Donghui Zhang
IPC分类号： C12N15/09 , A61K31/7088 , A61K31/711 , A61K39/00 , A61K39/12 , A61K39/21 , A61K39/385 , A61K39/395 , A61K47/48 , A61K48/00 , A61P1/04 , A61P3/10 , A61P5/50 , A61P17/00 , A61P17/06 , A61P25/00 , A61P29/00 , A61P35/00 , C07K14/16 , C07K14/28 , C07K19/00 , C12N5/10 , C12N15/34 , A61K9/127 , C12N15/86
CPC分类号： A61K39/0011 , A61K39/12 , A61K39/21 , A61K2039/5152 , A61K2039/5156 , A61K2039/53 , A61K2039/545 , A61K2039/55516 , A61K2039/55522 , A61K2039/57 , C12N2740/15034 , C12N2740/16034
摘要： Drug delivery compositions and methods of delivering compounds to specific cell types are disclosed. Vaccines and methods of immunizing individuals are disclosed. Compositions for drug delivery including gene therapy and methods of treating individuals using such compositions are disclosed.
摘要翻译：公开了将化合物递送到特定细胞类型的药物递送组合物和方法。公开了免疫个体的疫苗和方法。公开了用于药物递送的组合物，包括基因治疗和使用这些组合物治疗个体的方法。

4. 发明申请

US20110258212A1 AUTOMATIC QUERY SUGGESTION GENERATION USING SUB-QUERIES 审中-公开
标题翻译：使用子查询的自动查询建议生成
公开(公告)号：US20110258212A1
公开(公告)日：2011-10-20
申请号：US12760128
申请日：2010-04-14
申请人： JIANPING LU , DONGHUI ZHANG , HOWARD SHI KIN WAN
发明人： JIANPING LU , DONGHUI ZHANG , HOWARD SHI KIN WAN
IPC分类号： G06F17/30
CPC分类号： G06F16/951
摘要： Query suggestions can be generated by identifying desirable sub-queries. Search engine data can be accumulated to determine usage characteristics for various queries. Potential sub-queries can be generated and ranked based on the usage data. After ranking potential sub-queries, the rankings can be used to select sub-queries when a search request is received. The selected sub-queries can be used directly as query suggestions, or the sub-queries can be used as input for another query suggestion engine.
摘要翻译：可以通过识别所需的子查询来生成查询建议。可以累积搜索引擎数据以确定各种查询的使用特性。可以根据使用情况数据生成潜在的子查询和排名。在排列潜在的子查询之后，当接收到搜索请求时，排名可用于选择子查询。所选择的子查询可以直接用作查询建议，也可以将子查询用作另一查询建议引擎的输入。

5. 发明申请

US20070083019A1 Polymer synthesis from macrocycles 有权
标题翻译：大分子合成聚合物
公开(公告)号：US20070083019A1
公开(公告)日：2007-04-12
申请号：US11545092
申请日：2006-10-06
申请人： Donghui Zhang , William Tolman , Marc Hillmyer
发明人： Donghui Zhang , William Tolman , Marc Hillmyer
IPC分类号： C08F4/06
CPC分类号： C08G65/22 , C08G63/08 , C08G63/823
摘要： A synthetic route is provided to prepare poly(ω-hydroxycarboxylic acid) polymers via the ring-opening polymerization of ω-hydroxycarboxylic acid cyclic oligomers. The cyclic oligomers can be prepared directly from biorenewable sources, such as 3-hydroxypropionic acid. The method can be used to prepare high molecular weight polymers from the cyclic oligomers. Good molecular weight control can be obtained for both solution state and melt polymerizations.
摘要翻译：提供合成途径以通过ω-羟基羧酸环状低聚物的开环聚合制备聚（ω-羟基羧酸）聚合物。环状低聚物可以直接从生物可再生来源例如3-羟基丙酸制备。该方法可用于从环状低聚物制备高分子量聚合物。对于溶液状态和熔融聚合都可以获得良好的分子量控制。

6. 发明授权

US06881558B1 Expression system for cloning toxic genes 有权
标题翻译：用于克隆有毒基因的表达系统
公开(公告)号：US06881558B1
公开(公告)日：2005-04-19
申请号：US09888860
申请日：2001-06-25
申请人： David B. Weiner , Donghui Zhang , Adam Cohen
发明人： David B. Weiner , Donghui Zhang , Adam Cohen
IPC分类号： C12N15/72 , C12P21/06 , C07H21/04 , C12N1/12 , C12N15/00 , C12P21/04
CPC分类号： C12N15/72
摘要： Methods of cloning and/or amplifying toxic genes in bacteria using a vector which amplifies the toxic gene in bacteria and also allows subsequent expression in mammalian systems is provided. A vector having an origin of replication, a first promoter, a polylinker, a second promoter in reverse orientation with respect to the first promoter, a poly adenylation signal, and a gene encoding a selectable marker, and optionally an enhancer operably connected to the first promoter, and/or a nucleotide sequence encoding a toxic protein is also provided.
摘要翻译：使用扩增细菌中的毒性基因并允许随后在哺乳动物系统中表达的载体来克隆和/或扩增细菌中的有毒基因的方法。具有复制起点的载体，第一启动子，多接头体，相对于第一启动子反向取向的第二启动子，多腺苷酸化信号和编码可选择标记的基因，以及任选地可增强的与第一启动子连接的增强子启动子，和/或编码毒性蛋白质的核苷酸序列。

7. 发明申请

US20120323970A1 DYNAMIC LOCK-FREE HASH TABLES 有权
标题翻译：动态无锁HASH表
公开(公告)号：US20120323970A1
公开(公告)日：2012-12-20
申请号：US13163674
申请日：2011-06-18
申请人： Per-Ake Larson , Donghui Zhang
发明人： Per-Ake Larson , Donghui Zhang
IPC分类号： G06F17/30
CPC分类号： G06F17/30949
摘要： A table update component may perform updates on a dynamic linear hash table, the updates requested by clients based on request item values. A table capacity status component may determine first capacity indicators associated with the dynamic linear hash table, based on results of the update requests. A table maintenance component may initiate lock-free merges and lock-free splits of hash table buckets associated with the dynamic linear hash table, based on initiating lock-free merges and lock-free splits of linked lists included in hash table buckets associated with the dynamic linear hash table, based on the determined first capacity indicators, the linked lists including hashed items stored in the dynamic linear hash table.
摘要翻译：表更新组件可以在动态线性哈希表上执行更新，客户端基于请求项值请求更新。基于更新请求的结果，表容量状态组件可以确定与动态线性散列表相关联的第一容量指示符。表维护组件可以基于与包含在与哈希表相关联的散列表桶中包括的链接列表的无锁合并和无锁定分割来启动与动态线性散列表相关联的哈希表桶的无锁合并和无锁分割动态线性哈希表，基于确定的第一容量指示符，链表包括存储在动态线性哈希表中的散列项。

8. 发明申请

US20120230945A1 TARGETED PARTICLES AND METHODS OF USING THE SAME 有权
标题翻译：目标颗粒及其使用方法
公开(公告)号：US20120230945A1
公开(公告)日：2012-09-13
申请号：US13422864
申请日：2012-03-16
申请人： David B. Weiner , Karuppiah Muthumani , Donghui Zhang , Mathura P. Ramanathan
发明人： David B. Weiner , Karuppiah Muthumani , Donghui Zhang , Mathura P. Ramanathan
IPC分类号： A61K39/395 , A61P37/02 , C07K16/18 , C12N5/02 , A61K38/20
CPC分类号： C12N15/86 , A61K39/00 , A61K39/0011 , A61K2039/505 , A61K2039/5256 , A61K2039/5258 , A61K2039/53 , A61K2039/55522 , A61K2039/55555 , A61K2039/6031 , C07K14/005 , C07K14/475 , C07K14/70596 , C07K2319/00 , C07K2319/33 , C12N2740/16043 , C12N2740/16045 , C12N2740/16122 , C12N2740/16222 , C12N2740/16322 , C12N2810/855
摘要： Drug delivery compositions and methods of delivering compounds are disclosed. Vaccines and methods of immunizing individuals are disclosed. Compositions for drug delivery including gene therapy and methods of treating individuals using such compositions are disclosed.
摘要翻译：公开了递送组合物和递送化合物的方法。公开了免疫个体的疫苗和方法。公开了用于药物递送的组合物，包括基因治疗和使用这些组合物治疗个体的方法。

9. 发明申请

US20050054104A1 Targeted particles and methods of using the same 有权
标题翻译：目标粒子及其使用方法
公开(公告)号：US20050054104A1
公开(公告)日：2005-03-10
申请号：US10478896
申请日：2002-05-28
申请人： David Weiner , Karuppiah Muthumani , Donghui Zhang , Mathura Ramanthan
发明人： David Weiner , Karuppiah Muthumani , Donghui Zhang , Mathura Ramanthan
IPC分类号： A61K39/00 , C07K14/16 , C07K14/475 , C12N15/867 , C12N15/861
CPC分类号： C12N15/86 , A61K39/00 , A61K39/0011 , A61K2039/505 , A61K2039/5256 , A61K2039/5258 , A61K2039/53 , A61K2039/55522 , A61K2039/55555 , A61K2039/6031 , C07K14/005 , C07K14/475 , C07K14/70596 , C07K2319/00 , C07K2319/33 , C12N2740/16043 , C12N2740/16045 , C12N2740/16122 , C12N2740/16222 , C12N2740/16322 , C12N2810/855
摘要： Drug delivery compositions and methods of delivering compounds to are disclosed. Vaccines and methods of immunizing individuals are disclosed. Compositions for drug delivery including gene therapy and methods of treating individuals using such compositions are disclosed.
摘要翻译：药物递送组合物和递送化合物的方法被公开。公开了免疫个体的疫苗和方法。公开了用于药物递送的组合物，包括基因治疗和使用这些组合物治疗个体的方法。

10. 外观设计

USD907042S1 USB hub 有权
公开(公告)号：USD907042S1
公开(公告)日：2021-01-05
申请号：US29702233
申请日：2019-08-17
申请人： DongHui Zhang
设计人： DongHui Zhang

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