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1. 发明专利

AU7986998A Antigenomic oligodeoxynucleotides for treatment of infection by negative-stranded nonsegmented rna viruses 未知
公开(公告)号：AU7986998A
公开(公告)日：1999-01-19
申请号：AU7986998
申请日：1998-06-26
申请人： DIETZSCHOLD BERNHARD , FU ZHEN FANG , KOPROWSKI HILARY , WICKSTROM ERIC
发明人： FU ZHEN FANG , WICKSTROM ERIC , DIETZSCHOLD BERNHARD , KOPROWSKI HILARY
IPC分类号： A61K38/00 , C12N15/113 , A61K48/00 , C07H21/04 , C12Q1/68

2. 发明申请

WO1995009249A1 ORAL VACCINATION OF MAMMALS 审中-公开
标题翻译：肉食的口服疫苗
公开(公告)号：WO1995009249A1
公开(公告)日：1995-04-06
申请号：PCT/US1994011112
申请日：1994-09-30
申请人： THOMAS JEFFERSON UNIVERSITY , THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY , FU, Zhen, Fang , RUPPRECHT, Charles, E.
发明人： THOMAS JEFFERSON UNIVERSITY , THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY
IPC分类号： C12Q01/70
CPC分类号： C07K14/005 , A61K39/00 , A61K39/12 , A61K39/205 , A61K2039/5252 , A61K2039/5256 , A61K2039/542 , C07K2319/00 , C12N2710/14143 , C12N2740/16122 , C12N2760/20122 , C12N2760/20134
摘要： Oral anti-rabbies vaccines that comprise at least 100 mu g of an isolated rabies glycoprotein G that is produced in eukaryotic cells and methods of immunizing mammals against rabies infection which comprise the step of orally administering to the mammal, such oral anti-rabies vaccine are disclosed. Chimeric proteins are disclosed. Orally active vaccines for immunizing a mammal against a pathogen infection comprising chimeric proteins and methods of using the same are disclosed. Oral anti-pathogen vaccines that comprise at least 100 mu g of an isolated rabies glycoprotein G and either an isolated pathogen antigen or a peptide which comprises a neutralizing epitope of a pathogen antigen and methods of using the same are disclosed.
摘要翻译：包含至少100μg在真核细胞中产生的孤立的狂犬病糖蛋白G的口服抗狂犬病疫苗和包括向哺乳动物口服施用这种口服抗狂犬病疫苗的狂犬病感染免疫哺乳动物的方法是披露。公开了嵌合蛋白。公开了用于免疫哺乳动物免受包含嵌合蛋白质的病原体感染的口服活性疫苗及其使用方法。公开了包含至少100μg分离的狂犬病糖蛋白G和分离的病原体抗原或包含病原体抗原的中和表位的肽的口服抗病原体疫苗及其使用方法。

3. 发明申请

WO1997014290A1 SYNTHESIS OF IMMUNOLOGIC, THERAPEUTIC AND PROPHYLACTIC COMPOUNDS BY ENDOPHYTIC MICROORGANISMS 审中-公开
标题翻译：通过内源性微生物合成免疫，治疗和预防性化合物
公开(公告)号：WO1997014290A1
公开(公告)日：1997-04-24
申请号：PCT/US1996016638
申请日：1996-10-18
申请人： THOMAS JEFFERSON UNIVERSITY , CARLSON, Peter, Spikins , KOPROWSKI, Hilary , HOOPER, Douglas, Craig , CONWAY, Laura, Jane , MICHAELS, Frank, H. , MODELSKA, Anna , FU, Zhen, Fang
发明人： THOMAS JEFFERSON UNIVERSITY
IPC分类号： A01C01/06
CPC分类号： C07K14/005 , A61K38/00 , C07K14/325 , C12N15/74 , C12N15/8257 , C12N15/8258 , C12N2760/20122
摘要： A process for the synthesis and delivery of bioactive compounds, compounds that have a therapeutic, biochemical, or immunologic effect on an animal, such as human. In the process, an endophytic microorganism is genetically altered so that it synthesizes the bioactive compound. A plant may be infected with the genetically altered microorganism and used as an oral delivery system.
摘要翻译：用于合成和递送生物活性化合物的方法，对动物（例如人）具有治疗，生物化学或免疫学作用的化合物。在此过程中，内生微生物被遗传改变，从而合成生物活性化合物。植物可能被遗传改变的微生物感染并用作口服递送系统。

4. 发明授权

US09465751B2 Efficient locking of memory pages 有权
标题翻译：高效锁定内存页面
公开(公告)号：US09465751B2
公开(公告)日：2016-10-11
申请号：US13996438
申请日：2012-03-30
申请人： Xiaowei Jiang , Hongliang Gao , Zhen Fang , Srihari Makineni , Ravishankar Iyer
发明人： Xiaowei Jiang , Hongliang Gao , Zhen Fang , Srihari Makineni , Ravishankar Iyer
IPC分类号： G06F12/12 , G06F12/14 , G06F12/10
CPC分类号： G06F12/1466 , G06F12/1027 , G06F12/126
摘要： An apparatus is described that contains a processing core comprising a CPU core and at least one accelerator coupled to the CPU core. The CPU core comprises a pipeline having a translation look aside buffer. The CPU core comprising logic circuitry to set a lock bit in attribute data of an entry within the translation look-aside buffer entry to lock a page of memory reserved for the accelerator.
摘要翻译：描述了一种装置，其包含处理核心，其包括CPU核心和耦合到CPU核心的至少一个加速器。 CPU核心包括具有翻译旁边缓冲器的管线。 CPU核心包括逻辑电路，用于在转换后备缓冲器条目中的条目的属性数据中设置锁定位，以锁定为加速器保留的存储器页面。

5. 发明授权

US08819388B2 Control of on-die system fabric blocks 有权
标题翻译：管芯系统织物块的控制
公开(公告)号：US08819388B2
公开(公告)日：2014-08-26
申请号：US13550966
申请日：2012-07-17
申请人： Zhen Fang , Mahesh Wagh , Jasmin Ajanovic , Michael E. Espig , Ravishankar Iyer
发明人： Zhen Fang , Mahesh Wagh , Jasmin Ajanovic , Michael E. Espig , Ravishankar Iyer
IPC分类号： G06F12/00 , G06F12/10
CPC分类号： G06F12/1036 , G06F12/0292 , G06F12/0888 , G06F12/10 , G06F12/1027 , G06F2212/206
摘要： Methods and apparatus for control of On-Die System Fabric (OSF) blocks are described. In one embodiment, a shadow address corresponding to a physical address may be stored in response to a user-level request and a logic circuitry (e.g., present in an OSF) may determine the physical address from the shadow address. Other embodiments are also disclosed.
摘要翻译：描述了用于控制片上系统结构（OSF）块的方法和装置。在一个实施例中，响应于用户级请求可以存储对应于物理地址的影子地址，并且逻辑电路（例如，存在于OSF中）可以从影子地址确定物理地址。还公开了其他实施例。

6. 发明申请

US20140019736A1 Embedded Branch Prediction Unit 有权
标题翻译：嵌入式分支预测单元
公开(公告)号：US20140019736A1
公开(公告)日：2014-01-16
申请号：US13992723
申请日：2011-12-30
申请人： Xiaowei Jiang , Srihari Makineni , Zhen Fang , Dmitri Pavlov , Ravi Iyer
发明人： Xiaowei Jiang , Srihari Makineni , Zhen Fang , Dmitri Pavlov , Ravi Iyer
IPC分类号： G06F9/38
CPC分类号： G06F9/3806 , G06F9/30058
摘要： In accordance with some embodiments of the present invention, a branch prediction unit for an embedded controller may be placed in association with the instruction fetch unit instead of the decode stage. In addition, the branch prediction unit may include no branch predictor. Also, the return address stack may be associated with the instruction decode stage and is structurally separate from the branch prediction unit. In some cases, this arrangement reduces the area of the branch prediction unit, as well as power consumption.
摘要翻译：根据本发明的一些实施例，用于嵌入式控制器的分支预测单元可以与指令提取单元相关联而不是解码级放置。另外，分支预测单元也可以不包括分支预测器。此外，返回地址堆栈可以与指令解码级相关联，并且在结构上与分支预测单元分离。在某些情况下，这种布置减少了分支预测单元的面积以及功耗。

7. 发明申请

US20130274527A1 Method For The Dissolving And Rapid Hydrolyzing Of Lignocellulose Biomass, Device Thereof And Use Of the Same 有权
标题翻译：用于溶解和快速水解木质素纤维素生物质的方法及其使用方法
公开(公告)号：US20130274527A1
公开(公告)日：2013-10-17
申请号：US13876941
申请日：2011-07-04
申请人： Zhen Fang
发明人： Zhen Fang
IPC分类号： C13K1/02 , C07C29/00
CPC分类号： C13K1/02 , C07C29/00 , C08H8/00 , C09K3/00 , C12P7/10 , C12P2201/00 , C12P2203/00 , Y02E50/16 , Y02E50/17
摘要： A method for the dissolving and rapid hydrolyzing of the lignocellulose biomass and the device thereof are disclosed. The lignocellulose biomass is put in the pure water and rapidly heated to 330˜403° C., and then 89˜99% of the lignocellulose biomass is dissolved and rapidly hydrolyzed to saccharide in 3.38˜21.79 s. The following hydrolysis reaction can be carried out under the homogeneous phase condition for the dissolving of the lignocellulose biomass. At the same time, the solvated biomass could be easily used in the high pressure flow reactor to continuously pretreat the biomass and hydrolyze for producing saccharide, other biofuel and product. The present invention doesn't need any catalyst and doesn't pollute the environment, furthermore the process is simple and the cost is low, and it belongs to green, continuable industry encouraged by the state, and a good prospect of market application could be taken on.
摘要翻译：公开了一种用于溶解和快速水解木质纤维素生物质的方法及其装置。将木质纤维素生物质放入纯水中，迅速加热至330〜403℃，然后将木质纤维素生物质的89〜99％溶解并迅速水解成糖，为3.38〜21.79s。以下水解反应可以在均相条件下进行，用于溶解木质纤维素生物质。同时，溶剂化生物质可以容易地用于高压流动反应器中，以连续预处理生物质，并水解生产糖，其他生物燃料和产品。本发明不需要任何催化剂，不污染环境，而且工艺简单，成本低，属于国家鼓励绿色，可持续发展的行业，市场应用前景广阔被带走

8. 发明授权

US08412885B2 Searching a shared cache by using search hints and masked ways 失效
标题翻译：使用搜索提示和屏蔽方式搜索共享缓存
公开(公告)号：US08412885B2
公开(公告)日：2013-04-02
申请号：US12590651
申请日：2009-11-12
申请人： Liqun Cheng , Zhen Fang , Jeffrey Wilder , Sadagopan Srinivasan , Ravishankar Iyer , Donald Newell
发明人： Liqun Cheng , Zhen Fang , Jeffrey Wilder , Sadagopan Srinivasan , Ravishankar Iyer , Donald Newell
IPC分类号： G06F12/00
CPC分类号： G06F12/0895 , Y02D10/13
摘要： In an embodiment of the present invention a method includes: sending request for data to a memory controller; arranging the request for data by order of importance or priority; identifying a source of the request for data; and if the source is an input/output device, masking off P ways in a cache; and allocating ways in filling the cache. Other embodiments are described and claimed.
摘要翻译：在本发明的实施例中，一种方法包括：向存储器控制器发送数据请求; 按重要性或优先次序安排数据请求; 识别数据请求的来源; 并且如果源是输入/输出设备，则遮蔽高速缓存中的P路; 并分配填充缓存的方法。描述和要求保护其他实施例。

9. 发明授权

US08225069B2 Control of on-die system fabric blocks 有权
标题翻译：管芯系统结构块的控制
公开(公告)号：US08225069B2
公开(公告)日：2012-07-17
申请号：US12415941
申请日：2009-03-31
申请人： Zhen Fang , Mahesh Wagh , Jasmin Ajanovic , Michael E Espig , Ravishankar Iyer
发明人： Zhen Fang , Mahesh Wagh , Jasmin Ajanovic , Michael E Espig , Ravishankar Iyer
IPC分类号： G06F12/00
CPC分类号： G06F12/1036 , G06F12/0292 , G06F12/0888 , G06F12/10 , G06F12/1027 , G06F2212/206
摘要： Methods and apparatus for control of On-Die System Fabric (OSF) blocks are described. In one embodiment, a shadow address corresponding to a physical address may be stored in response to a user-level request and a logic circuitry (e.g., present in an OSF) may determine the physical address from the shadow address. Other embodiments are also disclosed.
摘要翻译：描述了用于控制片上系统结构（OSF）块的方法和装置。在一个实施例中，响应于用户级请求可以存储对应于物理地址的影子地址，并且逻辑电路（例如，存在于OSF中）可以从影子地址确定物理地址。还公开了其他实施例。

10. 发明申请

US20120067342A1 METHOD FOR COMPLETELY DISSOLVING AND RAPIDLY HYDROLYZING CELLULOSE, AND USES OF SAID METHOD 有权
标题翻译：完全溶解和快速水解纤维素的方法及其方法
公开(公告)号：US20120067342A1
公开(公告)日：2012-03-22
申请号：US13259526
申请日：2010-08-18
申请人： Zhen Fang
发明人： Zhen Fang
IPC分类号： C13K1/02
CPC分类号： C08B1/003 , C08B15/02 , C08L1/02 , Y02E50/16
摘要： The invention discloses a method for completely dissolving and rapidly hydrolyzing cellulose, and uses thereof. Cellulose is placed in an acidic aqueous solution with a [H+] concentration of 10−7˜1 M or an alkaline aqueous solution with a [OH−] concentration of 10−7˜1 M as sample A, wherein the volume ratio of solid to liquid is (0.003˜1.05):1. The acidic aqueous solution with a [H+] concentration of 10−7˜1 M or the alkaline aqueous solution with a [OH−] concentration of 10−7˜1 M is heated up to 261˜352 as sample B. Sample A and sample B obtained from step 1 and step 2 are mixed in a reactor to a concentration of cellulose of 0.1%˜35%, the concentration of the mixed solution is adjusted to an acidity of 10−7˜1 M [H+] or an alkalinity of 10−7˜1 M [OH−], and a water density of 587˜997 kg/m3, pressure is set at 6˜584 MPa. The mixture is rapidly heated up to 261˜352 at heating rate of 7.8˜14.8 /s, and then cellulose is dissolved completely in 0.8˜2 sec and hydrolyzed in 5 sec. Using this technique, it is the first time for achieving complete dissolution and rapid hydrolysis of cellulose at a lower temperature, which not only dramatically reduces the cost of hydrolysis but also improves the safety of production and extends the service life of equipment, thus possessing a good application prospect.
摘要翻译：本发明公开了一种完全溶解并快速水解纤维素的方法及其用途。将纤维素置于[H +]浓度为10-7〜1M的酸性水溶液或[OH-]浓度为10-7〜1M的碱性水溶液中作为样品A，其中固体的体积比液体为（0.003〜1.05）：1。 [H +]浓度为10-7〜1M的酸性水溶液或[OH-]浓度为10-7〜1M的碱性水溶液作为样品B加热至261〜352℃。样品A和将从步骤1和步骤2获得的样品B在反应器中混合至0.1％〜35％的纤维素浓度，将混合溶液的浓度调节至10-7〜1M [H +]的酸度或碱度的10-7〜1M [OH-]，水密度为587〜997kg / m3，压力设定为6〜58MPa。混合物以7.8〜14.8 / s的加热速率快速加热至261〜352℃，然后将纤维素完全溶解于0.8〜2秒钟，并在5秒钟内水解。使用这种技术，它是第一次在较低的温度下实现纤维素的完全溶解和快速水解，这不仅大大降低了水解成本，而且提高了生产的安全性并延长了设备的使用寿命，因此具有良好的应用前景。

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