专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20130289112A1 SALTS OF KUKOAMINE B, PREPARATION METHOD AND USE THEREOF 有权
标题翻译：库卡宾B的制备方法及其用途
公开(公告)号：US20130289112A1
公开(公告)日：2013-10-31
申请号：US13884558
申请日：2011-03-21
申请人： Jiang Zheng , Xinchuan Zheng , Xin Liu , Hong Zhou , Ning Wang , Hongwei Cao , Yan Li , Yongling Lu , Kecen Zhao , Jingcheng Yang , Yang Yang , Yuanfeng Zhu , Guo Wei , Min Huang
发明人： Jiang Zheng , Xinchuan Zheng , Xin Liu , Hong Zhou , Ning Wang , Hongwei Cao , Yan Li , Yongling Lu , Kecen Zhao , Jingcheng Yang , Yang Yang , Yuanfeng Zhu , Guo Wei , Min Huang
IPC分类号： C07C235/34 , C07C55/10 , C07C57/145 , C07C229/24 , C07C59/08 , C07C59/255 , C07C309/04 , C07C309/30 , C07C53/10 , C07C59/245
CPC分类号： C07C309/04 , C07C53/08 , C07C53/10 , C07C53/122 , C07C53/124 , C07C55/06 , C07C55/08 , C07C55/10 , C07C55/14 , C07C57/145 , C07C57/15 , C07C57/44 , C07C59/08 , C07C59/245 , C07C59/255 , C07C59/265 , C07C59/50 , C07C63/06 , C07C229/24 , C07C235/34 , C07C309/25 , C07C309/30
摘要： Salts of kukoamine B, their preparation method and their pharmaceutical use in preparation of drugs for preventing and treating sepsis. Experiments indicate that salts of kukoamine B have a good effect on antagonizing the key factors inducing sepsis, and can be used in the preparation of drugs for preventing and treating sepsis. Under the current circumstances of the lack of effective measures for the treatment of sepsis in clinical practice, the medicinal formulations, which comprise the salts of kukoamine B, pharmaceutically acceptable carrier and/or diluent, provide a new approach for the prevention and treatment of sepsis.
摘要翻译： kukoamine B的盐，它们的制备方法及其制备用于预防和治疗败血症药物的药物用途。实验表明，kukoamine B的盐对拮抗诱导败血症的关键因素具有很好的疗效，可用于制备预防和治疗败血症的药物。目前在临床实践中缺乏治疗败血症的有效措施的情况下，包含kukoamine B，药学上可接受的载体和/或稀释剂的盐的药物制剂提供了预防和治疗败血症的新方法。

2. 发明授权

US09365504B2 Salts of kukoamine B, preparation method and use thereof 有权
标题翻译： kukoamine B的盐，其制备方法和用途
公开(公告)号：US09365504B2
公开(公告)日：2016-06-14
申请号：US13884558
申请日：2011-03-21
申请人： Jiang Zheng , Xinchuan Zheng , Xin Liu , Hong Zhou , Ning Wang , Hongwei Cao , Yan Li , Yongling Lu , Kecen Zhao , Jingcheng Yang , Yang Yang , Yuanfeng Zhu , Guo Wei , Min Huang
发明人： Jiang Zheng , Xinchuan Zheng , Xin Liu , Hong Zhou , Ning Wang , Hongwei Cao , Yan Li , Yongling Lu , Kecen Zhao , Jingcheng Yang , Yang Yang , Yuanfeng Zhu , Guo Wei , Min Huang
IPC分类号： C07C37/02 , C07C235/34 , C07C309/04 , C07C53/08 , C07C55/10 , C07C59/08 , C07C59/245 , C07C59/255 , C07C53/10 , C07C57/145 , C07C229/24 , C07C309/30 , C07C53/122 , C07C53/124 , C07C55/06 , C07C55/08 , C07C55/14 , C07C57/15 , C07C57/44 , C07C59/265 , C07C59/50 , C07C63/06 , C07C309/25
CPC分类号： C07C309/04 , C07C53/08 , C07C53/10 , C07C53/122 , C07C53/124 , C07C55/06 , C07C55/08 , C07C55/10 , C07C55/14 , C07C57/145 , C07C57/15 , C07C57/44 , C07C59/08 , C07C59/245 , C07C59/255 , C07C59/265 , C07C59/50 , C07C63/06 , C07C229/24 , C07C235/34 , C07C309/25 , C07C309/30
摘要： Salts of kukoamine B, their preparation method and their pharmaceutical use in preparation of drugs for preventing and treating sepsis. Experiments indicate that salts of kukoamine B have a good effect on antagonizing the key factors inducing sepsis, and can be used in the preparation of drugs for preventing and treating sepsis. Under the current circumstances of the lack of effective measures for the treatment of sepsis in clinical practice, the medicinal formulations, which comprise the salts of kukoamine B, pharmaceutically acceptable carrier and/or diluent, provide a new approach for the prevention and treatment of sepsis.
摘要翻译： kukoamine B的盐，它们的制备方法及其制备用于预防和治疗败血症药物的药物用途。实验表明，kukoamine B的盐对拮抗诱导败血症的关键因素具有很好的疗效，可用于制备预防和治疗败血症的药物。目前在临床实践中缺乏治疗败血症的有效措施的情况下，包含kukoamine B，药学上可接受的载体和/或稀释剂的盐的药物制剂提供了预防和治疗败血症的新方法。

3. 发明申请

US20130172421A1 USE OF KUKOAMINE A AND KUKOAMINE B 审中-公开
标题翻译： KUKOAMINE A和KUKOAMINE B的使用
公开(公告)号：US20130172421A1
公开(公告)日：2013-07-04
申请号：US13638966
申请日：2011-03-21
申请人： Jiang Zheng , Xin Liu , Xinchuan Zheng , Hong Zhou , Hongwei Cao , Ning Wang , Yongling Lu
发明人： Jiang Zheng , Xin Liu , Xinchuan Zheng , Hong Zhou , Hongwei Cao , Ning Wang , Yongling Lu
IPC分类号： A61K31/165
CPC分类号： A61K31/165 , A61K36/815
摘要： The use of Kukoamine A and Kukoamine B in the preparation of drugs for the prevention and treatment of sepsis and autoimmune disease is disclosed. Bacterial endotoxin/lipopolysaccaride (LPS) and unmethylated DNA (CpG DNA) of bacteria, the major pathogen-associated molecular patterns in sepsis and autoimmune disease, are specifically targeted, while the disclosed use directionally isolates lead compounds from traditional Chinese medicine. These measures can overcome the major defects of uncertainty of pharmacological material basis and drug targets of extracts and constituents of traditional Chinese medicine. The disclosed use can help in developing a safe, effective and quality controllable drug for prevention and treatment of sepsis and autoimmune disease so as to help solve the present lack of effective drugs in clinical treatment.
摘要翻译：公开了使用Kukoamine A和Kukoamine B制备用于预防和治疗败血症和自身免疫疾病的药物。细菌内毒素/脂多糖（LPS）和细菌的未甲基化DNA（CpG DNA）是败血症和自身免疫性疾病中主要病原体相关分子模式的特异性靶向，而所公开的用途定向分离中药中的铅化合物。这些措施可以克服中药提取物和成分的药理学基础和药物靶标不确定性的主要缺陷。所公开的用途有助于开发一种安全，有效和质量可控的药物，用于预防和治疗败血症和自身免疫性疾病，以帮助解决目前缺乏有效药物的临床治疗。

4. 外观设计

USD827966S1 Garment folding apparatus 有权
公开(公告)号：USD827966S1
公开(公告)日：2018-09-04
申请号：US29602947
申请日：2017-05-05
申请人： Hong Zhou
设计人： Hong Zhou

5. 发明授权

US08112432B2 Query rewriting with entity detection 有权
标题翻译：查询重写与实体检测
公开(公告)号：US08112432B2
公开(公告)日：2012-02-07
申请号：US12420696
申请日：2009-04-08
申请人： Hong Zhou , Krishna Bharat , Michael Schmitt , Michael Curtiss , Marissa Mayer
发明人： Hong Zhou , Krishna Bharat , Michael Schmitt , Michael Curtiss , Marissa Mayer
IPC分类号： G06F17/30
CPC分类号： G06F17/30979 , G06F17/30864 , Y10S707/99934 , Y10S707/99935 , Y10S707/99945
摘要： A system receives a search query, determines whether the received search query includes an entity name, and determines whether the entity name is associated with a common word or phrase. When the entity name is associated with a common word or phrase, the system generates a link to a rewritten query, performs a search based on the received search query to obtain first search results, and provides the first search results and the link to the rewritten query. When the entity name is not associated with a common word or phrase, the system rewrites the received search query to include a restrict identifier associated with the entity name, generates a link to the received search query, performs a search based on the rewritten search query to obtain second search results, and provides the second search results and the link to the received search query.
摘要翻译：系统接收搜索查询，确定接收到的搜索查询是否包括实体名称，并确定实体名称是否与公共单词或短语相关联。当实体名称与通用单词或短语相关联时，系统生成到重写查询的链接，基于接收到的搜索查询执行搜索以获得第一搜索结果，并提供第一搜索结果和重写的链接查询。当实体名称不与公共词或短语相关联时，系统重写接收到的搜索查询以包括与实体名称相关联的限制标识符，生成到所接收的搜索查询的链接，基于重写的搜索查询执行搜索获得第二搜索结果，并提供第二搜索结果和链接到所接收的搜索查询。

6. 发明授权

US07916891B2 Apparatus for measurement of floating body posture of person wearing life jacket 失效
标题翻译：用于测量穿着救生衣的人身漂浮姿势的装置
公开(公告)号：US07916891B2
公开(公告)日：2011-03-29
申请号：US11779949
申请日：2007-07-19
申请人： Hong Zhou , Meiwu Shi , Hong Xiao , Fei Duan , Shiliang Dai , Jinyu Zhu
发明人： Hong Zhou , Meiwu Shi , Hong Xiao , Fei Duan , Shiliang Dai , Jinyu Zhu
IPC分类号： G06K9/00
CPC分类号： B63C9/08
摘要： Taught herein is an apparatus for measurement of floating body posture of a person wearing a life jacket, comprising a backpack frame having a plurality of reference points, an image collecting system, and an image processing system; wherein the image collecting system collects image sequence information of the person wearing the life jacket via the reference points; the image processing system processes the image sequence information, so as to obtain the dynamics of a movement of the person and the quasi-static parameters of such movement. The system is capable of reflecting the dynamics of a movement of a body in water and the quasi-static parameters thereof.
摘要翻译：本发明是一种测量穿着救生衣的人的浮体姿势的装置，包括具有多个参考点的背包框架，图像采集系统和图像处理系统; 其中所述图像采集系统经由所述参考点收集穿着救生衣的人的图像序列信息; 图像处理系统处理图像序列信息，以获得人的运动的动态和这种运动的准静态参数。该系统能够反映身体在水中的运动的动力学及其准静态参数。

7. 发明授权

US07536382B2 Query rewriting with entity detection 有权
标题翻译：查询重写与实体检测
公开(公告)号：US07536382B2
公开(公告)日：2009-05-19
申请号：US10813572
申请日：2004-03-31
申请人： Hong Zhou , Krishna Bharat , Michael Schmitt , Michael Curtiss , Marissa Mayer
发明人： Hong Zhou , Krishna Bharat , Michael Schmitt , Michael Curtiss , Marissa Mayer
IPC分类号： G06F17/30
CPC分类号： G06F17/30979 , G06F17/30864 , Y10S707/99934 , Y10S707/99935 , Y10S707/99945
摘要： A system receives a search query, determines whether the received search query includes an entity name, and determines whether the entity name is associated with a common word or phrase. When the entity name is associated with a common word or phrase, the system generates a link to a rewritten query, performs a search based on the received search query to obtain first search results, and provides the first search results and the link to the rewritten query. When the entity name is not associated with a common word or phrase, the system rewrites the received search query to include a restrict identifier associated with the entity name, generates a link to the received search query, performs a search based on the rewritten search query to obtain second search results, and provides the second search results and the link to the received search query.
摘要翻译：系统接收搜索查询，确定接收到的搜索查询是否包括实体名称，并确定实体名称是否与公共单词或短语相关联。当实体名称与通用单词或短语相关联时，系统生成到重写查询的链接，基于接收到的搜索查询执行搜索以获得第一搜索结果，并提供第一搜索结果和重写的链接查询。当实体名称不与公共词或短语相关联时，系统重写接收到的搜索查询以包括与实体名称相关联的限制标识符，生成到所接收的搜索查询的链接，基于重写的搜索查询执行搜索获得第二搜索结果，并提供第二搜索结果和链接到所接收的搜索查询。

8. 发明申请

US20050026514A1 Cable connector assembly and method of making the same 失效
标题翻译：电缆连接器组件及其制造方法
公开(公告)号：US20050026514A1
公开(公告)日：2005-02-03
申请号：US10903165
申请日：2004-07-30
申请人： Hong Zhou
发明人： Hong Zhou
IPC分类号： H01R4/02 , H01R9/05 , H01R13/405
CPC分类号： H01R4/023 , H01R9/05 , H01R13/405
摘要： A cable connector assembly (1) in accordance with the present invention includes a plug (3), a cable (4) and a fusible element (5). The plug comprises a terminal (30) having a connecting portion (301). The connecting portion defines a hole (304) extending through a first and an opposite second faces (302, 303) thereof. The fusible element is filled in the hole (304). The cable includes a wire (40) having a soldering portion (400). The soldering portion includes a first tail (401) and a second tail (402) respectively soldered onto the first and the second faces. The first and the second tails are connected with each other by the fusible element.
摘要翻译：根据本发明的电缆连接器组件（1）包括插头（3），电缆（4）和可熔元件（5）。插头包括具有连接部分（301）的端子（30）。连接部分限定了延伸通过其第一和相对的第二面（302,303）的孔（304）。可熔元件填充在孔（304）中。电缆包括具有焊接部分（400）的电线（40）。焊接部分包括分别焊接到第一和第二面上的第一尾部（401）和第二尾部（402）。第一和第二尾部通过可熔元件彼此连接。

9. 发明授权

US5925545A System for in vitro transposition 失效
公开(公告)号：US5925545A
公开(公告)日：1999-07-20
申请号：US850880
申请日：1997-05-02
申请人： William S. Reznikoff , Igor Yu Goryshin , Hong Zhou
发明人： William S. Reznikoff , Igor Yu Goryshin , Hong Zhou
IPC分类号： C12N15/09 , C12N9/22 , C12N15/55 , C12N15/85 , C12N15/90 , C12P21/06 , C07H21/04 , C12N15/00 , C07K13/00
CPC分类号： C12N15/85 , C12N15/90 , C12N9/22 , C12N2800/90
摘要： A system for in vitro transposition includes a donor DNA that includes a transposable element flanked by a pair of bacterial transposon Tn5 outside end repeat sequences, a target DNA into which the transposable element can transpose, and a modified Tn5 transposase having higher binding avidity to the outside end repeat sequences and being less likely to assume an inactive multimer form than wild type Tn5 transposase.

10. 外观设计

USD829005S1 Clothes folding board 有权
公开(公告)号：USD829005S1
公开(公告)日：2018-09-25
申请号：US29601619
申请日：2017-04-24
申请人： Hong Zhou
设计人： Hong Zhou

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式