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1. 发明授权

US06552024B1 Compositions and methods for mucosal delivery 失效
标题翻译：粘膜递送的组成和方法
公开(公告)号：US06552024B1
公开(公告)日：2003-04-22
申请号：US09434878
申请日：1999-11-05
申请人： Li-Lan H. Chen , William R. Pfister , Donald W. Renn , Thitiwan Buranachokpaisan , James Osborne , Hock Seng Tan , Li Tao
发明人： Li-Lan H. Chen , William R. Pfister , Donald W. Renn , Thitiwan Buranachokpaisan , James Osborne , Hock Seng Tan , Li Tao
IPC分类号： A61K31495
CPC分类号： A61K9/0007 , A61K9/0031 , A61K9/0034 , A61K9/0043 , A61K9/0056 , A61K9/006 , A61K9/145 , A61K9/1623 , A61K9/7007 , A61K9/7015 , A61K31/495 , A61K31/505
摘要： Mucosal surface-coat-forming film dosage units containing a water-soluble hydrocolloid, an effective dose of an active agent and a mucosal adhesion enhancer; wherein the active agent is encapsulated within a polymer which is chemically or physically distinct from the hydocolloid; wherein the mucosal adhesion enhancer is a starch graft copolymer; wherein the film exhibits a dry tack value of less than 3.5 g, a wet tack of greater than 35 g, a gelation temperature that is greater than 70° C. for a 2% polymer solution, a dry film thickness of less than 20 mil, a water content of 0.5 to 10%, a tensile strength greater than 1500 psi, a modulus in the range of 35,000 to 300,000 psi, a % elongation of less than 20%, a tear probagation resistance of 0.001 to 1 N, and a dissolution time in the range of 1 to 600 seconds upon application to an oral mucosal surface.
摘要翻译：含有水溶性水胶体的粘膜表面涂膜形成膜剂量单位，有效剂量的活性剂和粘膜粘附增强剂; 其中所述活性剂包封在化学或物理上不同于所述液体胶体的聚合物内; 其中粘膜粘附增强剂是淀粉接枝共聚物; 其中所述膜的干粘度值小于3.5g，湿粘性大于35g，对于2％聚合物溶液的凝胶化温度大于70℃，干膜厚度小于20密耳，水含量为0.5〜10％，拉伸强度大于1500psi，模量为35,000〜300,000psi，％伸长率小于20％，耐撕裂概率为0.001〜1N，施用于口腔粘膜表面后的溶出时间为1至600秒。

2. 发明授权

US5455344A Agarose compositions for nucleic acid sequencing 失效
标题翻译：用于核酸测序的琼脂糖组合物
公开(公告)号：US5455344A
公开(公告)日：1995-10-03
申请号：US116662
申请日：1993-09-03
申请人： David L. Harper , Jonathan H. Morgan , Samuel Nochumson , Mikhail V. Ostrovsky , Donald W. Renn , William C. Snow
发明人： David L. Harper , Jonathan H. Morgan , Samuel Nochumson , Mikhail V. Ostrovsky , Donald W. Renn , William C. Snow
IPC分类号： C08L5/00 , G01N27/447 , C08B37/00 , C08B37/12 , C12N15/10
CPC分类号： G01N27/44747 , C08L5/00
摘要： A nucleic acid sequencing gel comprising 2 to 10% of a gelling polysaccharide, preferably agarose; a denaturing agent, a non-gelling additive, preferably glycerol, and electrophoretic buffers. This composition is capable of resolving nucleic acid fragments having at least 50 bases and which differ from each other by at least one base.
摘要翻译：包含2至10％胶凝多糖，优选琼脂糖的核酸测序凝胶; 变性剂，非胶凝添加剂，优选甘油和电泳缓冲液。该组合物能够分解具有至少50个碱基并且彼此不同的至少一个碱基的核酸片段。

3. 发明授权

US07700172B2 Articles prepared from biodegradable compositions and manufacturing methods 有权
标题翻译：由可生物降解组合物制备的制品和制造方法
公开(公告)号：US07700172B2
公开(公告)日：2010-04-20
申请号：US12491029
申请日：2009-06-24
申请人： Donald W. Renn
发明人： Donald W. Renn
IPC分类号： B65D39/00
CPC分类号： B65D25/14 , B65D25/34 , B65D65/466 , Y02A40/961 , Y02W90/13 , Y10S220/30 , Y10S524/916 , Y10T428/13 , Y10T428/1348 , Y10T428/1352 , Y10T428/1372 , Y10T428/1376
摘要： A biodegradable container includes a body structure made of a foamed hydrocolloid gelling matrix system having a fibrous material and a firming agent embedded therein and a water-resistant coating disposed on a surface of the body structure.
摘要翻译：可生物降解的容器包括由发泡的水胶体胶凝基体体系构成的体结构，其具有纤维材料和嵌入其中的固化剂，以及设置在体结构表面上的防水涂层。

4. 发明申请

US20090263601A1 ARTICLES PREPARED FROM BIODEGRADABLE COMPOSITIONS AND MANUFACTURING METHODS 有权
标题翻译：由生物可降解组合物制备的制品和制造方法
公开(公告)号：US20090263601A1
公开(公告)日：2009-10-22
申请号：US12491029
申请日：2009-06-24
申请人： Donald W. Renn
发明人： Donald W. Renn
IPC分类号： B32B1/02 , B29C71/00 , B29C67/00
CPC分类号： B65D25/14 , B65D25/34 , B65D65/466 , Y02A40/961 , Y02W90/13 , Y10S220/30 , Y10S524/916 , Y10T428/13 , Y10T428/1348 , Y10T428/1352 , Y10T428/1372 , Y10T428/1376
摘要： A biodegradable container includes a body structure made of a foamed hydrocolloid gelling matrix system having a fibrous material and a firming agent embedded therein and a water-resistant coating disposed on a surface of the body structure.
摘要翻译：可生物降解的容器包括由发泡的水胶体胶凝基体体系构成的体结构，其具有纤维材料和嵌入其中的固化剂，以及设置在体结构表面上的防水涂层。

5. 发明申请

US20070292643A1 Biodegradable compositions, articles prepared from biodegradable compositions and manufacturing methods 有权
标题翻译：可生物降解组合物，由可生物降解组合物制备的制品和制造方法
公开(公告)号：US20070292643A1
公开(公告)日：2007-12-20
申请号：US11454272
申请日：2006-06-16
申请人： Donald W. Renn
发明人： Donald W. Renn
IPC分类号： B32B27/08
CPC分类号： B65D25/14 , B65D25/34 , B65D65/466 , Y02A40/961 , Y02W90/13 , Y10S220/30 , Y10S524/916 , Y10T428/13 , Y10T428/1348 , Y10T428/1352 , Y10T428/1372 , Y10T428/1376
摘要： Biodegradable compositions that include a foamed gelling hydrocolloid system to which a firming agent and a fibrous material, with or without other optional components, are added. When articles prepared from such compositions are coated with a suitable coating, they are impervious to boiling water and able to withstand microwave heating.
摘要翻译：可生物降解的组合物包括泡沫胶凝水胶体体系，其中加入固化剂和纤维材料，具有或不含有其它任选组分。当由这样的组合物制备的制品涂覆合适的涂层时，它们不受沸水的影响，并且能够承受微波加热。

6. 发明授权

US4659672A Colony replicating device 失效
标题翻译：菌落复制装置
公开(公告)号：US4659672A
公开(公告)日：1987-04-21
申请号：US345966
申请日：1982-02-05
申请人： Richard B. Provonchee , Donald W. Renn
发明人： Richard B. Provonchee , Donald W. Renn
IPC分类号： C12M1/26 , C12M1/00
CPC分类号： C12M23/20 , C12M23/10 , C12M25/16 , C12M33/14
摘要： A device for replicating microbial or other cell colonies or aggregates comprises a layer of moisture absorbent material either in the form of a coherent film or comprising individual particles or a combination of film and particles, said layer being secured to a suitable handle forming element by means of which the device may be manipulated.
摘要翻译：用于复制微生物或其他细胞集落或聚集物的装置包括一层吸湿材料，其形式为粘膜或包含单个颗粒或膜和颗粒的组合，所述层通过装置固定到合适的手柄形成元件可以操纵该装置。

7. 发明授权

US3975162A Applying reagent to medium and device therefor 失效
标题翻译：将试剂用于培养基及其装置
公开(公告)号：US3975162A
公开(公告)日：1976-08-17
申请号：US450615
申请日：1974-03-13
申请人： Donald W. Renn
发明人： Donald W. Renn
IPC分类号： C12Q1/32 , G01N33/558 , G01N33/92 , G01N31/06 , G01N33/16
CPC分类号： G01N33/558 , C12Q1/32 , G01N33/92
摘要： Device for applying a measured quantity of water-soluble or water-dispersible reagent to a water-containing solid medium for use in molecular diffusion or affinity separation procedures is provided in the form of a film consisting essentially of a film-forming solid organic polymeric binder which is soluble in water to the extent of at least 1% by weight at 20.degree.C. and dispersed in said binder a measured quantity of said reagent, said film being of a size and shape adapted to be placed in contact with said medium to permit said reagent and binder to diffuse completely into said medium. The device is used by placing it in face-to-face contact with a water-containing solid medium.
摘要翻译：以测量量的水溶性或水分散性试剂施加到用于分子扩散或亲和力分离程序的含水固体介质中的装置以基本上由成膜固体有机聚合物粘合剂其在20℃下可溶于至少1重量％的程度，并在所述粘合剂中分散测量量的所述试剂，所述膜的尺寸和形状适于与所述介质接触，允许所述试剂和粘合剂完全扩散到所述介质中。通过将其与含水固体介质面对面接触来使用该装置。

8. 发明授权

US07618485B2 Biodegradable compositions, articles prepared from biodegradable compositions and manufacturing methods 有权
标题翻译：可生物降解组合物，由可生物降解组合物制备的制品和制造方法
公开(公告)号：US07618485B2
公开(公告)日：2009-11-17
申请号：US11454272
申请日：2006-06-16
申请人： Donald W. Renn
发明人： Donald W. Renn
IPC分类号： C08L1/26
CPC分类号： B65D25/14 , B65D25/34 , B65D65/466 , Y02A40/961 , Y02W90/13 , Y10S220/30 , Y10S524/916 , Y10T428/13 , Y10T428/1348 , Y10T428/1352 , Y10T428/1372 , Y10T428/1376
摘要： Biodegradable compositions that include a foamed gelling hydrocolloid system to which a firming agent and a fibrous material, with or without other optional components, are added. When articles prepared from such compositions are coated with a suitable coating, they are impervious to boiling water and able to withstand microwave heating.
摘要翻译：可生物降解的组合物包括泡沫胶凝水胶体体系，其中加入固化剂和纤维材料，具有或不含有其它任选组分。当由这样的组合物制备的制品涂覆合适的涂层时，它们不受沸水的影响，并且能够承受微波加热。

9. 发明授权

US5624612A Nonaggregating hydrocolloid microparticulates, intermediates therefor, and processes for their preparation 失效
标题翻译：非聚集水胶体微粒，其中间体及其制备方法
公开(公告)号：US5624612A
公开(公告)日：1997-04-29
申请号：US476989
申请日：1995-06-07
申请人： Christopher J. Sewall , Donald W. Renn , Peter J. Riley , William R. Thomas , Lisa E. Dumont , Guy A. Crosby
发明人： Christopher J. Sewall , Donald W. Renn , Peter J. Riley , William R. Thomas , Lisa E. Dumont , Guy A. Crosby
IPC分类号： A23D7/005 , A23D7/015 , A23D7/05 , A23D9/007 , A23L1/00 , A23L1/0522 , A23L1/0532 , A23L1/0534 , A23L1/214 , A23L1/22 , B01J13/02 , B01J13/04
CPC分类号： A23D9/007 , A23D7/0056 , A23D7/015 , A23D7/05 , A23L19/115 , A23L27/72 , A23L29/212 , A23L29/256 , A23L29/262 , A23P10/30 , A23P10/35 , A23P10/40 , Y10S426/804 , Y10T428/249953 , Y10T428/249955 , Y10T428/249958 , Y10T428/2991 , Y10T428/2998
摘要： Substantially dry, rehydratable, water-dispersible, gel-forming, porous hydrocolloid microparticulates containing internally or internally and externally at least one water-soluble, non-gelling, hydration enhancing hydrocolloid, processes and intermediates for their preparation, and their uses.
摘要翻译：含有内部或内部和外部至少一种水溶性，非胶凝，水合增强水胶体，其制备方法和中间体及其用途的基本干燥，可再水化，水分散性，凝胶形成，多孔水解胶体微粒。

10. 发明授权

US4952686A Soluble dried cassia alloy gum composition and process for making same 失效
标题翻译：可溶性干果桂皮合成胶组合物及其制备方法
公开(公告)号：US4952686A
公开(公告)日：1990-08-28
申请号：US127347
申请日：1987-12-01
申请人： Donald W. Renn , George E. Lauterbach , Peter Hemmingsen
发明人： Donald W. Renn , George E. Lauterbach , Peter Hemmingsen
IPC分类号： C08C1/15 , A23L29/238 , A23L29/269 , C08C1/00 , C08J3/03 , C08L5/00 , C08L5/14 , C08L33/24 , C08L33/26
CPC分类号： C08J3/03 , A23L29/238 , A23L29/269 , C08L5/14 , C08J2305/14
摘要： A process and composition is provided for a hydratable, alloy gum composition of Cassia gum and another gelling and thickening agent which composition is capable of forming a clear, stable colloidal solution. The compositions are usually more easily dispersed in an aqueous solution than either component alone. An alloy gum composition of Cassia gum and xanthan gum is particularly useful for absorbing an aqueous medium.

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