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41. 发明授权

US06408214B1 Deflectable tip catheter for CS pacing 失效
标题翻译：用于CS起搏的偏转尖端导管
公开(公告)号：US06408214B1
公开(公告)日：2002-06-18
申请号：US09614131
申请日：2000-07-11
申请人： Terrell M. Williams , Kenneth C. Gardeski
发明人： Terrell M. Williams , Kenneth C. Gardeski
IPC分类号： A61N118
CPC分类号： A61M25/0662 , A61M25/0041 , A61N2001/0578 , A61N2001/0585
摘要： A deflectable tip introducer or guide catheter optimized for placement of leads or catheters within the vasculature of the human body is disclosed. The introducer includes inner and outer concentrically located tubular sheaths. The inner and outer sheaths are preferably provided with different curved configurations, allowing the over-all displayed curvature of the introducer over its distal portion to be adjusted by longitudinal movement of the inner and outer sheaths relative to one another. The outer sheath may be fabricated of a thin tube of polyetheretherketone (PEEK) or other material having a relatively large stiffness as compared to the inner sheath. The outer sheath is sized to fit closely around the inner sheath. The inner sheath may be formed of a reinforced polyurethane, and preferably has a thin wall that is of about 0.005 inches in thickness or less. When supported by the inner sheath, the outer sheath transfers torque along the composite introducer assembly and serves to modify the curved configuration displayed by the distal end of the introducer assembly in conjunction with the relative longitudinal movement of the inner and outer sheaths.
摘要翻译：公开了一种针对人体脉管系统中引线或导管放置的可偏转尖端引导器或引导导管。引导器包括内部和外部同心的管状护套。内护套和外护套优选地设置有不同的弯曲构造，允许通过内护套和外护套相对于彼此的纵向运动来调节引导器在其远侧部分上的全部显示的曲率。外护套可以由聚醚醚酮（PEEK）的薄管或与内护套相比具有相对较大刚度的其他材料制成。外护套的尺寸设计成紧密地配合在内护套周围。内护套可以由增强的聚氨酯形成，并且优选地具有厚度为约0.005英寸或更小的薄壁。当由内护套支撑时，外护套沿着复合导引器组件传递扭矩，并用于结合内护套和外护套的相对纵向运动来修改由导引器组件的远端显示的弯曲构型。

42. 发明授权

US06027462A Method and apparatus for deflecting a screw-in-lead 失效
标题翻译：用于偏转螺旋导线的方法和装置
公开(公告)号：US06027462A
公开(公告)日：2000-02-22
申请号：US126569
申请日：1998-07-30
申请人： Corinne A. Greene , Kenneth C. Gardeski , Andrzej Malewicz , Brett R. Johnson
发明人： Corinne A. Greene , Kenneth C. Gardeski , Andrzej Malewicz , Brett R. Johnson
IPC分类号： A61M25/01 , A61B5/00
CPC分类号： A61M25/0147 , A61M25/0136
摘要： An apparatus for deflecting a catheter or lead, for example a deflectable stylet or guidewire. The device includes an outer tubular member, a tension member mounted within the outer tubular member and coupled to the outer member and a handle mounted at the proximal end of the tubular member. The handle includes a major handle portion which has a rotatable knob located at its distal end, surrounding a proximal portion of the outer tubular member and provided with inwardly directed threading and an inner slider member provided with outwardly directed threading engaging the inwardly directed threading of the knob. The slider is advanced or retracted longitudinally within the handle by rotation of the knob but is rotationally fixed with regard to the major handle portion. The outer tubular member is engaged at its proximal end with the inner slider member and the tension wire is fixedly engaged with the major handle portion, whereby rotation of the knob results in advancement or retraction of the outer tubular member relative to the tension wire and the major portion of the handle, which in turn causes the deflection of the outer tubular member.
摘要翻译：用于使导管或引线偏转的装置，例如可偏转的探针或导丝。该装置包括外部管状构件，安装在外部管状构件内并联接到外部构件的张紧构件和安装在管状构件的近端处的手柄。手柄包括主把手部分，其具有位于其远端处的可旋转旋钮，围绕外部管状构件的近侧部分并且设置有向内引导的螺纹和设置有向外指向的螺纹的内部滑动构件，旋钮滑块通过旋钮旋转而在手柄内纵向前进或缩回，但相对于主把手部分旋转固定。外部管状构件在其近端处与内部滑动构件接合，并且张力线与主把手部分固定地接合，由此旋钮的旋转导致外部管状构件相对于张力线的前进或缩回，并且手柄的主要部分又导致外部管状构件的偏转。

43. 发明授权

US09572982B2 Techniques for placing medical leads for electrical stimulation of nerve tissue 有权
标题翻译：放置用于电刺激神经组织的医疗线的技术
公开(公告)号：US09572982B2
公开(公告)日：2017-02-21
申请号：US12433766
申请日：2009-04-30
申请人： John E. Burnes , Kenneth C. Gardeski , Ruth N. Klepfer , Patrick E. Macaulay , Mary M. Morris , Avram Scheiner
发明人： John E. Burnes , Kenneth C. Gardeski , Ruth N. Klepfer , Patrick E. Macaulay , Mary M. Morris , Avram Scheiner
IPC分类号： A61B19/00 , A61N1/36 , A61N1/05 , A61M25/09
CPC分类号： A61N1/36053 , A61M25/09 , A61N1/05 , A61N1/0551 , A61N1/0558 , A61N1/057 , A61N1/36085 , A61N1/36114 , A61N1/36125 , A61N1/36128
摘要： This disclosure is directed to extra, intra, and transvascular medical lead placement techniques for arranging medical leads and electrical stimulation and/or sensing electrodes proximate nerve tissue within a patient.
摘要翻译：本公开涉及用于在患者体内靠近神经组织布置医疗引线和电刺激和/或感测电极的额外的，内部的和经血管内的医疗引线放置技术。

44. 发明授权

US09067042B2 Steerable stylet with guidewire tip 有权
标题翻译：导丝针尖的导向通心针
公开(公告)号：US09067042B2
公开(公告)日：2015-06-30
申请号：US12771265
申请日：2010-04-30
申请人： Kenneth C. Gardeski , Ronald A. Drake
发明人： Kenneth C. Gardeski , Ronald A. Drake
IPC分类号： A61M25/01
CPC分类号： A61M25/0138 , A61M25/0133 , A61M25/0136 , A61M25/0147 , A61M2025/0161
摘要： According to an embodiment of the present invention, a steerable elongated medical device includes an outer tube extending between an outer tube proximal segment and an outer tube distal segment, and having an outer tube wall forming an outer tube lumen and an elongated outer tube slot through the outer tube wall to the outer tube lumen. The elongated outer tube slot has a first portion and a second portion and is formed between an outer tube slot proximal end and an outer tube slot distal end and extends axially along the outer tube distal segment through an outer tube slot length to define a cutaway portion of the outer tube. A reinforcing sleeve is positioned within the outer tube lumen and extends between a reinforcing sleeve proximal end and a reinforcing sleeve distal end. The reinforcing sleeve forms a reinforcing sleeve slot portion aligned with and extending along the first portion of the outer tube slot and includes a reinforcing sleeve overlap portion extending over the second portion of the outer tube slot. A handle is coupled to the outer tube proximal end, and a pull wire is positioned within the outer tube lumen and extends between a pull wire proximal end coupled to the handle and a pull wire distal end comprising a guidewire tip. The pull wire extends through the reinforcing sleeve lumen, the outer tube lumen, and a distal pull wire stop, and the guidewire tip extending distally from the distal pull wire stop and the pull wire proximal end is adapted to be manipulated to separate the pull wire proximal end from the outer tube proximal end to induce a bend in the cutaway portion.
摘要翻译：根据本发明的实施例，可操纵的细长医疗装置包括在外管近端段和外管远端段之间延伸的外管，并且具有形成外管内腔的外管壁和细管外管槽外管壁到外管腔。细长的外管狭槽具有第一部分和第二部分，并且形成在外管狭缝近端和外管狭槽远端之间，并且通过外管狭槽长度沿着外管远端段轴向延伸以限定切除部分的外管。加强套筒定位在外管腔内并且在加强套管近端和加强套管远端之间延伸。加强套管形成与外管槽的第一部分对准并沿其延伸的加强套管槽部分，并且包括在外管槽的第二部分上延伸的加强套管重叠部分。手柄耦合到外管近端，并且拉线定位在外管腔内并且在联接到手柄的拉线近端和包括导丝末端的拉线远端之间延伸。拉线延伸穿过加强套管腔，外管腔和远端拉线止动器，并且从远端牵引线止动件和拉线近端向远侧延伸的导丝末端适于被操纵以分离拉线近端从外管近端引起切口部分中的弯曲。

45. 发明授权

US08942784B2 Therapy delivery system including a navigation element 有权
标题翻译：治疗传递系统包括导航元件
公开(公告)号：US08942784B2
公开(公告)日：2015-01-27
申请号：US13095085
申请日：2011-04-27
申请人： Michael R. Neidert , Kenneth C. Gardeski , Johnson E. Goode , Mark D. Schneider
发明人： Michael R. Neidert , Kenneth C. Gardeski , Johnson E. Goode , Mark D. Schneider
IPC分类号： A61B5/055 , A61B19/00 , A61B5/00 , A61B10/04 , A61B17/12 , A61B18/00 , A61B18/14 , A61B18/18 , A61B17/34
CPC分类号： A61B19/5244 , A61B5/0084 , A61B5/055 , A61B5/6852 , A61B10/04 , A61B17/1214 , A61B17/3478 , A61B18/1492 , A61B18/18 , A61B34/20 , A61B34/25 , A61B90/36 , A61B90/39 , A61B2018/00071 , A61B2018/00839 , A61B2034/2051 , A61B2090/3958
摘要： An electromagnetic receiver assembly is included in a navigation element for a therapy delivery system. If the system is modular, the navigation element may be an insertable module thereof and/or include a lumen to receive another insertable module.
摘要翻译：用于治疗传送系统的导航元件中包括电磁接收器组件。如果系统是模块化的，则导航元件可以是其可插入模块和/或包括用于接收另一可插入模块的内腔。

46. 发明授权

US08734397B2 System and method for positioning implantable medical devices within coronary veins 有权
标题翻译：将植入式医疗器械定位在冠状静脉内的系统和方法
公开(公告)号：US08734397B2
公开(公告)日：2014-05-27
申请号：US12357810
申请日：2009-01-22
申请人： Stanten C. Spear , James F. Kelley , Kenneth C. Gardeski , Mohmoud K. Seraj , Eric K. Y. Chan
发明人： Stanten C. Spear , James F. Kelley , Kenneth C. Gardeski , Mohmoud K. Seraj , Eric K. Y. Chan
IPC分类号： A61M5/178
CPC分类号： A61M25/0668 , A61B18/1492 , A61B2017/22038 , A61B2018/00386 , A61M25/005 , A61M25/0051 , A61M25/0054 , A61M25/008 , A61M25/0138 , A61M25/0141 , A61M25/0147 , A61M2025/0042 , A61M2025/0047 , A61M2025/0081 , A61M2025/0161 , A61M2025/0681 , A61M2025/1052 , A61M2025/1079 , A61N1/056 , A61N2001/0578 , A61N2001/0585
摘要： An improved system and method for placing implantable medical devices (IMDs) such as leads within the coronary sinus and branch veins is disclosed. In one embodiment, a slittable delivery sheath and a method of using the sheath are provided. The sheath includes a slittable hub, and a substantially straight body defining an inner lumen. The body comprises a shaft section and a distal section that is distal to, and softer than, the shaft section. A slittable braid extends adjacent to at least a portion of one of the shaft section and the distal section. In one embodiment of the invention, the sheath further includes a transition section that is distal to the shaft section, and proximal to the distal section. The transition section is softer than the shaft section, but stiffer than the distal section.
摘要翻译：公开了用于在冠状窦和分支静脉内放置诸如引线的可植入医疗装置（IMD）的改进的系统和方法。在一个实施例中，提供了可切割的输送护套和使用护套的方法。护套包括可切割的毂，以及限定内腔的基本上直的身体。主体包括轴部分和远离轴部分的远端部分和远端部分。狭缝编织物相邻于轴部和远端部分中的一个的至少一部分延伸。在本发明的一个实施例中，护套还包括在轴部分的远侧并且靠近远端部分的过渡部分。过渡部分比轴部分软，但比远端部分更硬。

47. 发明授权

US08636694B2 Modular medical injection system 有权
标题翻译：模块化注射系统
公开(公告)号：US08636694B2
公开(公告)日：2014-01-28
申请号：US10867059
申请日：2004-06-14
申请人： Michael R. Neidert , Kenneth C. Gardeski , David F. Quinn , Russell J. Redmond , Michael Collinson , Claude A. Vidal
发明人： Michael R. Neidert , Kenneth C. Gardeski , David F. Quinn , Russell J. Redmond , Michael Collinson , Claude A. Vidal
IPC分类号： A61M5/178
CPC分类号： A61M25/0068 , A61M25/0097 , A61M25/0102 , A61M25/0606 , A61M25/0662 , A61M2025/0004 , A61M2025/0073
摘要： A medical injection system includes an elongate injection apparatus and an actuator apparatus. The actuator apparatus includes a fitting for coupling the actuator apparatus to a delivery catheter and a reversible gripping means to grip the injection apparatus; the gripping means is included in a plunger that is slideably engaged with the fitting and directs the injection apparatus through a fitting lumen and through a catheter lumen, when the fitting is coupled to the catheter.
摘要翻译：医疗注射系统包括细长注射装置和致动器装置。致动器装置包括用于将致动器装置连接到输送导管的配件和用于夹紧注射装置的可逆夹持装置; 夹紧装置被包括在与配件可滑动地接合的柱塞中，并且当配件联接到导管时，引导注射装置通过配合内腔并通过导管腔。

48. 发明授权

US08340783B2 Implantable medical device lead with selectively exposed electrodes and reinforcement member 有权
标题翻译：植入式医疗器械引线带有选择性暴露的电极和加强构件
公开(公告)号：US08340783B2
公开(公告)日：2012-12-25
申请号：US12825647
申请日：2010-06-29
申请人： John L. Sommer , Kenneth C. Gardeski , Xiaonan Shen , Jon D. Schell
发明人： John L. Sommer , Kenneth C. Gardeski , Xiaonan Shen , Jon D. Schell
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/05 , A61N1/0534 , A61N1/0551 , A61N1/0558 , A61N1/086
摘要： An implantable lead including a lead body including an outer surface, a proximal end, a distal end, and at least one electrode; an electrically insulating member that extends axially over a first portion of the outer surface of the lead body between the proximal end and distal end, the electrically insulating member defining at least one aperture that exposes a first portion of the at least one electrode when in a first position over the lead body; and a reinforcement member formed at least partially of a different material than the insulating member and coupled to the insulating member, the reinforcement member extending axially over the outer surface of the lead body between the insulating member and proximal end. The reinforcement member may be configured to transfer at least one of a radial or axial force from a proximal portion of the reinforcement member to the insulating member, wherein the at least one of radial or axial force transferred to the insulating member is sufficient to move the insulating member over the outer surface of the lead body. In some examples, the lead may further include a deployable lobe member configured to anchor the reinforcement member and insulating member adjacent a tissue site within a patient.
摘要翻译：一种可植入引线，包括：引线本体，其包括外表面，近端，远端和至少一个电极; 电绝缘构件，其在所述近端和远端之间轴向延伸到所述引线本体的外表面的第一部分上方，所述电绝缘构件限定在至少一个孔处暴露所述至少一个电极的第一部分，领先身体的第一位; 至少部分地由与所述绝缘构件不同的材料形成并且与所述绝缘构件连接的加强构件，所述加强构件在所述绝缘构件和所述绝缘构件与所述绝缘构件之间的所述引线本体的外表面上轴向延伸。加强构件可以构造成将径向或轴向力中的至少一个从加强构件的近侧部分传递到绝缘构件，其中传递到绝缘构件的径向或轴向力中的至少一个足以使绝缘构件在引线体的外表面上。在一些示例中，引线还可包括可展开的隆起部件，其构造成将加强部件和绝缘部件固定在患者体内的组织部位附近。

49. 发明授权

US08323248B2 Medical fluid delivery system 有权
标题翻译：医疗液体输送系统
公开(公告)号：US08323248B2
公开(公告)日：2012-12-04
申请号：US12822009
申请日：2010-06-23
申请人： Mary M. Morris , Michael R. Neidert , Kenneth C. Gardeski
发明人： Mary M. Morris , Michael R. Neidert , Kenneth C. Gardeski
IPC分类号： A61M5/178
CPC分类号： A61M5/158 , A61M25/0084
摘要： A medical fluid delivery system is provided including a steerable, guide catheter, a delivery catheter adapted for deployment at a targeted tissue site using the steerable guide catheter, the delivery catheter including a proximal port, a distal port, and a lumen extending between the proximal and distal ports; a distal fixation element coupled to the delivery catheter so as to position the distal port adjacent the targeted tissue site; and a flexible hollow needle adapted to be advanced through the delivery catheter lumen, the flexible needle including a tissue-piercing distal tip for extending from the distal port of the delivery catheter for advancement into the targeted tissue site and a proximal end for extending from the proximal port of the delivery catheter through which a medical fluid is delivered.
摘要翻译：提供了一种医疗流体输送系统，其包括可转向的导向导管，适于使用可转向引导导管在目标组织部位展开的输送导管，所述输送导管包括近端口，远端口和在近端和远端口; 远端固定元件，其联接到所述输送导管，以便将所述远端口邻近所述目标组织部位定位; 以及柔性中空针，其适于前进穿过输送导管腔，所述柔性针包括组织穿刺远侧末端，用于从输送导管的远端延伸进入目标组织部位，并且近端从输送导管的近端口，通过该端口传送医用流体。

50. 发明申请

US20110270171A1 Steerable Medical Device Having Means For Imparting Multiple Curves in the Device 审中-公开
公开(公告)号：US20110270171A1
公开(公告)日：2011-11-03
申请号：US12771393
申请日：2010-04-30
申请人： Kenneth C. Gardeski , Ronald A. Drake
发明人： Kenneth C. Gardeski , Ronald A. Drake
IPC分类号： A61M25/092
CPC分类号： A61M25/0133 , A61M25/0136
摘要： A steerable elongated medical device that is capable of forming as “s” shaped bend and having a guidewire tip at its distal end. The devices include an outer tube extending between an outer tube proximal segment and an outer tube distal segment, having an outer tube wall forming an outer tube lumen and first and second elongated outer tube slots through the outer tube wall to the outer tube lumen. The first elongated outer tube slot has a first portion and a second portion and formed between a first outer tube slot proximal end and a first outer tube slot distal end and extending axially along the outer tube distal segment through a first outer tube slot length to define a first cutaway portion of the outer tube. The second elongated outer tube slot has a first portion and a second portion and formed between a second outer tube slot proximal end and a second outer tube slot distal end and extending axially along the outer tube distal segment through a second outer tube slot length to define a second cutaway portion of the outer tube and offset about 180 degrees from the first elongated outer tube slot. Each of the first and second outer tube slots have reinforcing sleeves, each of the reinforcing sleeves having reinforcing sleeve slot portions and reinforcing sleeve overlap portions. The medical devices further include a handle coupled to the outer tube proximal end, and a pull wire positioned within the outer tube lumen and extending between a pull wire proximal end coupled to the handle and a pull wire distal end comprising a guidewire tip, the pull wire extending through the first and second reinforcing sleeve lumens, the outer tube lumen, and a distal pull wire stop, and the guidewire tip extending distally from the distal pull wire stop, wherein the pull wire proximal end is adapted to be manipulated to separate the pull wire proximal end from the outer tube proximal end to induce a bend in each of the first and second cutaway portions.

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