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1. 发明申请

US20090276022A1 TECHNIQUES FOR PLACING MEDICAL LEADS FOR ELECTRICAL STIMULATION OF NERVE TISSUE 审中-公开
公开(公告)号：US20090276022A1
公开(公告)日：2009-11-05
申请号：US12433773
申请日：2009-04-30
申请人： John E. Burnes , Kenneth C. Gardeski , Ruth N. Klepfer , Patrick E. Macaulay , Mary M. Morris , Avram Scheiner
发明人： John E. Burnes , Kenneth C. Gardeski , Ruth N. Klepfer , Patrick E. Macaulay , Mary M. Morris , Avram Scheiner
IPC分类号： A61N1/05
CPC分类号： A61N1/36053 , A61M25/09 , A61N1/05 , A61N1/0551 , A61N1/0558 , A61N1/057 , A61N1/36085 , A61N1/36114 , A61N1/36125 , A61N1/36128
摘要： This disclosure is directed to extra, intra, and transvascular medical lead placement techniques for arranging medical leads and electrical stimulation and/or sensing electrodes proximate nerve tissue within a patient.

2. 发明申请

US20090275956A1 TECHNIQUES FOR PLACING MEDICAL LEADS FOR ELECTRICAL STIMULATION OF NERVE TISSUE 有权
公开(公告)号：US20090275956A1
公开(公告)日：2009-11-05
申请号：US12433766
申请日：2009-04-30
申请人： John E. Burnes , Kenneth C. Gardeski , Ruth N. Klepfer , Patrick E. Macaulay , Mary M. Morris , Avram Scheiner
发明人： John E. Burnes , Kenneth C. Gardeski , Ruth N. Klepfer , Patrick E. Macaulay , Mary M. Morris , Avram Scheiner
IPC分类号： A61B17/00
CPC分类号： A61N1/36053 , A61M25/09 , A61N1/05 , A61N1/0551 , A61N1/0558 , A61N1/057 , A61N1/36085 , A61N1/36114 , A61N1/36125 , A61N1/36128
摘要： This disclosure is directed to extra, intra, and transvascular medical lead placement techniques for arranging medical leads and electrical stimulation and/or sensing electrodes proximate nerve tissue within a patient.

3. 发明授权

US09572982B2 Techniques for placing medical leads for electrical stimulation of nerve tissue 有权
标题翻译：放置用于电刺激神经组织的医疗线的技术
公开(公告)号：US09572982B2
公开(公告)日：2017-02-21
申请号：US12433766
申请日：2009-04-30
申请人： John E. Burnes , Kenneth C. Gardeski , Ruth N. Klepfer , Patrick E. Macaulay , Mary M. Morris , Avram Scheiner
发明人： John E. Burnes , Kenneth C. Gardeski , Ruth N. Klepfer , Patrick E. Macaulay , Mary M. Morris , Avram Scheiner
IPC分类号： A61B19/00 , A61N1/36 , A61N1/05 , A61M25/09
CPC分类号： A61N1/36053 , A61M25/09 , A61N1/05 , A61N1/0551 , A61N1/0558 , A61N1/057 , A61N1/36085 , A61N1/36114 , A61N1/36125 , A61N1/36128
摘要： This disclosure is directed to extra, intra, and transvascular medical lead placement techniques for arranging medical leads and electrical stimulation and/or sensing electrodes proximate nerve tissue within a patient.
摘要翻译：本公开涉及用于在患者体内靠近神经组织布置医疗引线和电刺激和/或感测电极的额外的，内部的和经血管内的医疗引线放置技术。

4. 发明授权

US07758521B2 Methods and systems for accessing the pericardial space 有权
标题翻译：用于获取心包空间的方法和系统
公开(公告)号：US07758521B2
公开(公告)日：2010-07-20
申请号：US11000539
申请日：2004-12-01
申请人： Mary M Morris , Kenneth C. Gardeski , Michael R. Ujhelyi , Michael E. Leckrone
发明人： Mary M Morris , Kenneth C. Gardeski , Michael R. Ujhelyi , Michael E. Leckrone
IPC分类号： A61M25/00 , A61M25/01
CPC分类号： A61B17/3478 , A61B17/00234 , A61B17/3417 , A61B18/1492 , A61B2017/00247 , A61B2017/003 , A61B2017/22077 , A61B2017/3484 , A61B2017/3488 , A61B2017/349 , A61B2018/00291 , A61B2018/00357 , A61B2018/00392 , A61M25/0084 , A61M2025/0037
摘要： Methods and systems for transvenously accessing the pericardial space via the vascular system and atrial wall, particularly through the superior vena cava and right atrial wall, to deliver treatment in the pericardial space are disclosed. A steerable instrument is advanced transvenously into the right atrium of the heart, and a distal segment is deflected into the right atrial appendage. A fixation catheter is advanced employing the steerable instrument to affix a distal fixation mechanism to the atrial wall. A distal segment of an elongated medical device, e.g., a therapeutic catheter or an electrical medical lead, is advanced through the fixation catheter lumen, through the atrial wall, and into the pericardial space. The steerable guide catheter is removed, and the elongated medical device is coupled to an implantable medical device subcutaneously implanted in the thoracic region. The fixation catheter may be left in place.
摘要翻译：公开了通过血管系统和心房壁，特别是通过上腔静脉和右心房壁经心脏进入心包空间的方法和系统，以在心包空间中递送治疗。一个可操纵的器械被递送到心脏的右心房，远端部分被偏转到右心耳。使用可操纵的器械来前进固定导管，以将远端固定机构固定在心房壁上。细长医疗装置（例如治疗性导管或电气医用引线）的远端部分通过固定导管内腔前进通过心房壁并进入心包空间。可移动的导向导管被移除，并且细长的医疗装置被联接到皮下植入胸部区域的可植入医疗装置。固定导管可以留在原位。

5. 发明申请

US20100249729A1 Methods and Systems for Accessing the Pericardial Space 有权
标题翻译：用于获取心包空间的方法和系统
公开(公告)号：US20100249729A1
公开(公告)日：2010-09-30
申请号：US12815624
申请日：2010-06-15
申请人： Mary M. Morris , Kenneth C. Gardeski , Michael R. Ujhelyi , Michael E. Leckrone
发明人： Mary M. Morris , Kenneth C. Gardeski , Michael R. Ujhelyi , Michael E. Leckrone
IPC分类号： A61M5/32 , A61N1/00
CPC分类号： A61B17/3478 , A61B17/00234 , A61B17/3417 , A61B18/1492 , A61B2017/00247 , A61B2017/003 , A61B2017/22077 , A61B2017/3484 , A61B2017/3488 , A61B2017/349 , A61B2018/00291 , A61B2018/00357 , A61B2018/00392 , A61M25/0084 , A61M2025/0037
摘要： Methods and systems for transvenously accessing the pericardial space via the vascular system and atrial wall, particularly through the superior vena cava and right atrial wall, to deliver treatment in the pericardial space are disclosed. A steerable instrument is advanced transvenously into the right atrium of the heart, and a distal segment is deflected into the right atrial appendage. A fixation catheter is advanced employing the steerable instrument to affix a distal fixation mechanism to the atrial wall. A distal segment of an elongated medical device, e.g., a therapeutic catheter or an electrical medical lead, is advanced through the fixation catheter lumen, through the atrial wall, and into the pericardial space. The steerable guide catheter is removed, and the elongated medical device is coupled to an implantable medical device subcutaneously implanted in the thoracic region. The fixation catheter may be left in place.
摘要翻译：公开了通过血管系统和心房壁，特别是通过上腔静脉和右心房壁经心脏进入心包空间的方法和系统，以在心包空间中递送治疗。一个可操纵的器械被递送到心脏的右心房，远端部分被偏转到右心耳。使用可操纵的器械来前进固定导管，以将远端固定机构固定在心房壁上。细长医疗装置（例如治疗性导管或电气医用引线）的远端部分通过固定导管内腔前进通过心房壁并进入心包空间。可移动的导向导管被移除，并且细长的医疗装置被联接到皮下植入胸部区域的可植入医疗装置。固定导管可以留在原位。

6. 发明授权

US08323248B2 Medical fluid delivery system 有权
标题翻译：医疗液体输送系统
公开(公告)号：US08323248B2
公开(公告)日：2012-12-04
申请号：US12822009
申请日：2010-06-23
申请人： Mary M. Morris , Michael R. Neidert , Kenneth C. Gardeski
发明人： Mary M. Morris , Michael R. Neidert , Kenneth C. Gardeski
IPC分类号： A61M5/178
CPC分类号： A61M5/158 , A61M25/0084
摘要： A medical fluid delivery system is provided including a steerable, guide catheter, a delivery catheter adapted for deployment at a targeted tissue site using the steerable guide catheter, the delivery catheter including a proximal port, a distal port, and a lumen extending between the proximal and distal ports; a distal fixation element coupled to the delivery catheter so as to position the distal port adjacent the targeted tissue site; and a flexible hollow needle adapted to be advanced through the delivery catheter lumen, the flexible needle including a tissue-piercing distal tip for extending from the distal port of the delivery catheter for advancement into the targeted tissue site and a proximal end for extending from the proximal port of the delivery catheter through which a medical fluid is delivered.
摘要翻译：提供了一种医疗流体输送系统，其包括可转向的导向导管，适于使用可转向引导导管在目标组织部位展开的输送导管，所述输送导管包括近端口，远端口和在近端和远端口; 远端固定元件，其联接到所述输送导管，以便将所述远端口邻近所述目标组织部位定位; 以及柔性中空针，其适于前进穿过输送导管腔，所述柔性针包括组织穿刺远侧末端，用于从输送导管的远端延伸进入目标组织部位，并且近端从输送导管的近端口，通过该端口传送医用流体。

7. 发明授权

US08000807B2 Methods and systems for accessing the pericardial space 有权
标题翻译：用于获取心包空间的方法和系统
公开(公告)号：US08000807B2
公开(公告)日：2011-08-16
申请号：US12815624
申请日：2010-06-15
申请人： Mary M Morris , Kenneth C. Gardeski , Michael R. Ujhelyi , Michael E. Leckrone
发明人： Mary M Morris , Kenneth C. Gardeski , Michael R. Ujhelyi , Michael E. Leckrone
IPC分类号： A61N1/05 , A61B18/00
CPC分类号： A61B17/3478 , A61B17/00234 , A61B17/3417 , A61B18/1492 , A61B2017/00247 , A61B2017/003 , A61B2017/22077 , A61B2017/3484 , A61B2017/3488 , A61B2017/349 , A61B2018/00291 , A61B2018/00357 , A61B2018/00392 , A61M25/0084 , A61M2025/0037
摘要： Methods and systems for transvenously accessing the pericardial space via the vascular system and atrial wall, particularly through the superior vena cava and right atrial wall, to deliver treatment in the pericardial space are disclosed. A steerable instrument is advanced transvenously into the right atrium of the heart, and a distal segment is deflected into the right atrial appendage. A fixation catheter is advanced employing the steerable instrument to affix a distal fixation mechanism to the atrial wall. A distal segment of an elongated medical device, e.g., a therapeutic catheter or an electrical medical lead, is advanced through the fixation catheter lumen, through the atrial wall, and into the pericardial space. The steerable guide catheter is removed, and the elongated medical device is coupled to an implantable medical device subcutaneously implanted in the thoracic region. The fixation catheter may be left in place.
摘要翻译：公开了通过血管系统和心房壁，特别是通过上腔静脉和右心房壁经心脏进入心包空间的方法和系统，以在心包空间中递送治疗。一个可操纵的器械被递送到心脏的右心房，远端部分被偏转到右心耳。使用可操纵的器械来前进固定导管，以将远端固定机构固定在心房壁上。细长医疗装置（例如治疗性导管或电气医用引线）的远端部分通过固定导管内腔前进通过心房壁并进入心包空间。可移动的导向导管被移除，并且细长的医疗装置被联接到皮下植入胸部区域的可植入医疗装置。固定导管可以留在原位。

8. 发明申请

US20100262001A1 MEDICAL FLUID DELIVERY SYSTEM 有权
标题翻译：医用流体输送系统
公开(公告)号：US20100262001A1
公开(公告)日：2010-10-14
申请号：US12822009
申请日：2010-06-23
申请人： Mary M. Morris , Michael R. Neidert , Kenneth C. Gardeski
发明人： Mary M. Morris , Michael R. Neidert , Kenneth C. Gardeski
IPC分类号： A61M25/00 , A61B5/05
CPC分类号： A61M5/158 , A61M25/0084
摘要： A medical fluid delivery system is provided including a steerable, guide catheter, a delivery catheter adapted for deployment at a targeted tissue site using the steerable guide catheter, the delivery catheter including a proximal port, a distal port, and a lumen extending between the proximal and distal ports; a distal fixation element coupled to the delivery catheter so as to position the distal port adjacent the targeted tissue site; and a flexible hollow needle adapted to be advanced through the delivery catheter lumen, the flexible needle including a tissue-piercing distal tip for extending from the distal port of the delivery catheter for advancement into the targeted tissue site and a proximal end for extending from the proximal port of the delivery catheter through which a medical fluid is delivered.
摘要翻译：提供了一种医疗流体输送系统，其包括可转向的导向导管，适于使用可转向引导导管在目标组织部位展开的输送导管，所述输送导管包括近端口，远端口和在近端和远端口; 远端固定元件，其联接到所述输送导管，以便将所述远端口邻近所述目标组织部位定位; 以及柔性中空针，其适于前进穿过输送导管腔，所述柔性针包括组织穿刺远侧末端，用于从输送导管的远端延伸进入目标组织部位，以及近端从输送导管的近端口，通过该端口传送医用流体。

9. 发明申请

US20120165902A1 MULTI-ELECTRODE IMPLANTABLE SYSTEMS AND ASSEMBLIES THEREOF 有权
标题翻译：多电极可植入系统及其组合
公开(公告)号：US20120165902A1
公开(公告)日：2012-06-28
申请号：US13008524
申请日：2011-01-18
申请人： John Louis Sommer , Joseph Michael D'Sa , Joyce K. Yamamoto , Brad C. Tischendorf , James D. Reinke , Andrew J. Thom , Thomas P. Miltich , William John Taylor , Kenneth C. Gardeski , Larry Earl Tyler , Jeffrey O. York , Gordon O. Munns
发明人： John Louis Sommer , Joseph Michael D'Sa , Joyce K. Yamamoto , Brad C. Tischendorf , James D. Reinke , Andrew J. Thom , Thomas P. Miltich , William John Taylor , Kenneth C. Gardeski , Larry Earl Tyler , Jeffrey O. York , Gordon O. Munns
IPC分类号： A61N1/36
CPC分类号： A61N1/362 , A61N1/05 , A61N1/056 , A61N1/372
摘要： Hermetically sealed assemblies, for example, that include IC chips, are configured for incorporation within a connector terminal of an implantable medical electrical lead, preferably within a contact member of the terminal. An assembly may include two feedthrough subassemblies, welded to either end of the contact member, to form an hermetic capsule, in which an IC chip is enclosed, and a tubular member, which allows a lumen to extend therethrough, along a length of the terminal. A multi-electrode lead may include multiplexer circuitry, preferably a switch matrix element and a communications, control and power supply element that are electrically coupled to the contact member and to another contact member of the terminal. Each pair of switch matrix switches allows for any two of the electrodes to be selected, in order to deliver a stimulation vector, via stimulation pulses from a device/pulse generator, to which the connector terminal is connected.
摘要翻译：例如，包括IC芯片的密封组件被配置为并入可植入医疗电线的连接器端子内，优选地在端子的接触构件内。组件可以包括焊接到接触构件的任一端的两个馈通子组件，以形成封闭IC芯片的密封胶囊，以及允许内腔沿着端子的长度延伸穿过的管状构件。多电极引线可以包括多路复用器电路，优选地是开关矩阵元件和通信，控制和电源元件，其电耦合到接触构件和终端的另一接触构件。每对开关矩阵开关允许选择任何两个电极，以便通过连接器端子连接到的装置/脉冲发生器的刺激脉冲传送刺激矢量。

10. 发明申请

US20110201921A1 Therapy Delivery System Including a Navigation Element 审中-公开
标题翻译：包括导航元素的治疗传递系统
公开(公告)号：US20110201921A1
公开(公告)日：2011-08-18
申请号：US13095085
申请日：2011-04-27
申请人： Michael R. Neidert , Kenneth C. Gardeski , Johnson E. Goode , Mark D. Schneider
发明人： Michael R. Neidert , Kenneth C. Gardeski , Johnson E. Goode , Mark D. Schneider
IPC分类号： A61B5/055
CPC分类号： A61B19/5244 , A61B5/0084 , A61B5/055 , A61B5/6852 , A61B10/04 , A61B17/1214 , A61B17/3478 , A61B18/1492 , A61B18/18 , A61B34/20 , A61B34/25 , A61B90/36 , A61B90/39 , A61B2018/00071 , A61B2018/00839 , A61B2034/2051 , A61B2090/3958
摘要： An electromagnetic receiver assembly is included in a navigation element for a therapy delivery system. If the system is modular, the navigation element may be an insertable module thereof and/or include a lumen to receive another insertable module.
摘要翻译：用于治疗传送系统的导航元件中包括电磁接收器组件。如果系统是模块化的，则导航元件可以是其可插入模块和/或包括用于接收另一可插入模块的内腔。

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