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1. 发明公开

US20240226448A9 MICRO-VOLUME INJECTORS WITH DOSE GUIDANCE AND METHODS FOR USE 审中-公开
公开(公告)号：US20240226448A9
公开(公告)日：2024-07-11
申请号：US18239055
申请日：2023-08-28
申请人： ALTAVIZ, LLC
发明人： John C. Huculak , Jack R. Auld , Hien Nguyen , Tammo Heeren , Matthew McCawley , Eric Anderfaas , John C. Dunne, JR.
IPC分类号： A61M5/315 , A61F9/00 , A61M5/24 , A61M5/28
CPC分类号： A61M5/31568 , A61F9/0008 , A61M5/24 , A61M5/281 , A61M5/3157 , A61M5/31581 , A61M2205/3306 , A61M2205/3317 , A61M2205/3368 , A61M2205/3584 , A61M2205/502 , A61M2205/52 , A61M2205/581 , A61M2205/584 , A61M2205/587
摘要： Injector devices and methods for using them to deliver medicament into a patient's body, e.g., sub-retinally within an eye, are provided. The injector includes a cartridge including a piston slidably disposed within an interior for delivering medicament within the interior through an outlet, and a driver including a plunger coupled to the piston, a source of pressurized fluid, and an actuator member for opening a flow path at least partially between the source and the plunger to advance the plunger and piston to deliver medicament from the interior. One or more sensors are operatively coupled to the plunger to measure displacement of the plunger, a processor is coupled to the sensor(s) for analyzing sensor signals to measure volume of medicament delivered from the interior, and an output device, e.g., one or more LEDs or speakers, provide outputs related to the volume of medicament delivered.

2. 发明授权

US11738154B2 Micro-volume injectors with dose guidance and methods for use 有权
公开(公告)号：US11738154B2
公开(公告)日：2023-08-29
申请号：US17019133
申请日：2020-09-11
申请人： ALTAVIZ, LLC
发明人： John C. Huculak , Jack R. Auld , Hien Nguyen , Tammo Heeren , Matthew McCawley , Eric Anderfaas , John C. Dunne, Jr.
IPC分类号： A61M5/315 , A61M5/24 , A61M5/28 , A61F9/00
CPC分类号： A61M5/31568 , A61F9/0008 , A61M5/24 , A61M5/281 , A61M5/3157 , A61M5/31581 , A61M2205/3306 , A61M2205/3317 , A61M2205/3368 , A61M2205/3584 , A61M2205/502 , A61M2205/52 , A61M2205/581 , A61M2205/584 , A61M2205/587
摘要： Injector devices and methods for using them to deliver medicament into a patient's body, e.g., sub-retinally within an eye, are provided. The injector includes a cartridge including a piston slidably disposed within an interior for delivering medicament within the interior through an outlet, and a driver including a plunger coupled to the piston, a source of pressurized fluid, and an actuator member for opening a flow path at least partially between the source and the plunger to advance the plunger and piston to deliver medicament from the interior. One or more sensors are operatively coupled to the plunger to measure displacement of the plunger, a processor is coupled to the sensor(s) for analyzing sensor signals to measure volume of medicament delivered from the interior, and an output device, e.g., one or more LEDs or speakers, provide outputs related to the volume of medicament delivered.

3. 发明授权

US10912883B2 Gas-powered fluid injection system 有权
公开(公告)号：US10912883B2
公开(公告)日：2021-02-09
申请号：US16180001
申请日：2018-11-04
申请人： ALTAVIZ, LLC
发明人： Matthew McCawley , Andrew Schieber , Matthew Flowers , Jack R. Auld , Marcus Souza
IPC分类号： A61M37/00 , A61M5/155 , A61M5/20 , A61M5/48 , A61M5/315 , A61M5/24 , A61M5/14
摘要： Gas-powered fluid injection systems and methods are disclosed, e.g., for delivering fluids into a patient's body. An injection device comprises a driver housing which forms and/or encloses a gas pressure source, an actuation piston driven by the gas pressure source and a hydraulic fluid pressurized by movement of the actuation piston. The hydraulic fluid flows through an adjustable valve into a plunger lumen which pushes a plunger of a fluid dispensing device, such as a syringe, to dispense an injection fluid, such as a medicament. The injection device has a movable plunger sleeve which receives the plunger of the fluid dispensing device. The plunger sleeve is moved during the activation and de-activation of the injection device such that it relieves residual pressure in the fluid dispensing device thereby preventing the fluid dispensing device from continuing to dispense injection fluid after the injection device has been de-actuated.

4. 发明授权

US08998983B2 Intraocular lens inserters 有权
标题翻译：人工晶体插入器
公开(公告)号：US08998983B2
公开(公告)日：2015-04-07
申请号：US14291743
申请日：2014-05-30
申请人： Altaviz, LLC
发明人： Jack R. Auld
IPC分类号： A61F2/16
CPC分类号： A61F2/167 , A61F2/1662 , A61F2/1678 , A61F9/007
摘要： An intraocular lens inserter can include an energy storage portion, an actuator portion, and a lens support portion. The energy storage portion can include a compressible energy storage device, such as a compressible fluid, springs, and other devices. The inserter can include an actuator portion operating with a substantially incompressible fluid, such as liquids or other noncompressible fluids. The actuator can be configured to provide an operator with control over the release of energy from the energy storage portion so as to move a plunger for the discharge of a lens from an intraocular lens cartridge.
摘要翻译：眼内透镜插入器可以包括能量存储部分，致动器部分和透镜支撑部分。能量存储部分可以包括可压缩能量存储装置，例如可压缩流体，弹簧和其它装置。插入器可以包括用基本上不可压缩的流体操作的致动器部分，例如液体或其它不可压缩的流体。致动器可以被配置为向操作者提供对来自能量存储部分的能量释放的控制，以便移动用于从眼内透镜盒排出镜头的柱塞。

5. 发明公开

US20240261508A1 INJECTION DEVICES AND METHODS FOR MAKING AND USING THEM 审中-公开
公开(公告)号：US20240261508A1
公开(公告)日：2024-08-08
申请号：US18433332
申请日：2024-02-05
申请人： ALTAVIZ, LLC
发明人： Jack R. Auld , Andrew Schieber , Matthew McCawley , Matthew Flowers , Yule Kim , Marcus Souza
IPC分类号： A61M5/20 , A61M5/32
CPC分类号： A61M5/2046 , A61M5/2066 , A61M5/322
摘要： Devices and methods are provided for delivering an agent into a patient's body using an injection device that includes a drive module and an injector module coupled to the drive module. The drive module includes a canister and puncture mechanism in a first chamber, a plunger in a second chamber communicating with the first chamber, and an actuator that moves the puncture mechanism to cause a puncture pin thereon to penetrate a septum of the canister and cause the gas within the canister to flow through the first chamber around the canister, and into the second chamber. The injector module includes a piston slidably disposed within an agent chamber and coupled to the distal end of the plunger such that, when the plunger moves from a retracted position to an extended position, the piston is advanced within the agent chamber to deliver an agent therein into a patient's body.

6. 发明申请

US20220257863A1 EXTERNALLY POWERED SYRINGE DRIVERS AND SYSTEMS AND METHODS FOR USING THEM 有权
公开(公告)号：US20220257863A1
公开(公告)日：2022-08-18
申请号：US17670441
申请日：2022-02-12
申请人： ALTAVIZ, LLC
发明人： Jack R. Auld , Matthew McCawley , John Dunne
IPC分类号： A61M5/20
摘要： Syringe drivers and injector devices are provided. The driver includes a housing including a port communicating with a gas chamber therein and connectable to an external air source, and a cavity that receives a syringe containing an agent. A drive piston within the housing includes a first end disposed adjacent the gas chamber and a second end including a plunger connectable to the syringe. A damping mechanism is provided within that housing that is coupled to the drive piston that includes a damper piston within a damping fluid chamber such that, when the drive piston is advanced by gas delivered into the gas chamber from the external source to deliver the agent from the syringe, damping fluid within the damping fluid chamber flows through an orifice or valve from a first region to the second region, thereby limiting movement of the drive piston.

7. 发明授权

US10716892B2 Self-powered syringe drivers 有权
公开(公告)号：US10716892B2
公开(公告)日：2020-07-21
申请号：US15582731
申请日：2017-04-30
申请人： ALTAVIZ, LLC
发明人： Jack R. Auld , Matthew Flowers , Matthew McCawley , John C. Huculak , Andrew Scheiber , James Lescoulie
IPC分类号： A61M5/14 , A61M5/145 , A61M5/20 , A61M5/24 , A61M5/48
摘要： Devices and methods are provided for delivering fluid into a patient's body. In an exemplary embodiment, the device may include a syringe cartridge and a syringe driver that may be coupled to the cartridge. The cartridge may include a housing including a proximal end, a distal end, and defining an interior, the cartridge further including a piston slidably disposed within the interior for delivering fluid within the interior through a port in the distal end. The driver may include a plunger for advancing the piston within the interior of the housing, a source of pressurized fluid, a valve, and an actuator member coupled to the valve for selectively opening a flow path from the source to the plunger to control flow of the pressurized fluid to advance the plunger to deliver fluid from the interior of the housing at a desired rate.

8. 发明授权

US09393370B2 Viscous fluid injector 有权
标题翻译：粘液注射器
公开(公告)号：US09393370B2
公开(公告)日：2016-07-19
申请号：US13899439
申请日：2013-05-21
申请人： Ataviz LLC
发明人： Jack R Auld , John C Huculak , Matthew McCawley
IPC分类号： A61M1/00 , A61M5/48 , A61M5/20 , A61F9/00
CPC分类号： A61M5/482 , A61F9/0017 , A61M5/2046
摘要： A self-contained apparatus and corresponding methods are provided for delivering viscous fluids in a controlled manner, such as delivering a viscous fluid in a surgical setting. The self-contained apparatus can include a motion following pressure regulator that allows for linear control of a regulated pressure. The regulated pressure can be used for dispensing a viscous fluid from a syringe that is coupled to the self-contained apparatus. The pressure regulator regulates a pressure derived from a pressurized fluid reservoir located at least partially within a housing of the apparatus. This allows the viscous fluid to be delivered using pressure to provide a driving force greater than a force easily delivered manually, while still allowing a surgeon to retain fine control over the rate of viscous fluid delivery.
摘要翻译：提供了一种独立的装置和相应的方法，用于以受控的方式输送粘性流体，例如在手术设置中输送粘性流体。独立设备可以包括运动跟随压力调节器，其允许线性控制调节压力。调节压力可用于从耦合到独立装置的注射器分配粘性流体。压力调节器调节从至少部分地位于装置的壳体内的加压流体储存器产生的压力。这允许使用压力输送粘性流体以提供大于手动容易输送的力的驱动力，同时仍允许外科医生保持对粘性流体输送速率的精细控制。

9. 发明授权

US11890453B2 Injection devices and methods for making and using them 有权
公开(公告)号：US11890453B2
公开(公告)日：2024-02-06
申请号：US16870952
申请日：2020-05-09
申请人： ALTAVIZ, LLC
发明人： Jack R. Auld , Andrew Schieber , Matthew McCawley , Matthew Flowers , Yule Kim , Marcus Souza
IPC分类号： A61M5/20 , A61M5/32
CPC分类号： A61M5/2046 , A61M5/2066 , A61M5/322
摘要： Devices and methods are provided for delivering an agent into a patient's body using an injection device that includes a drive module and an injector module coupled to the drive module. The drive module includes a canister and puncture mechanism in a first chamber, a plunger in a second chamber communicating with the first chamber, and an actuator that moves the puncture mechanism to cause a puncture pin thereon to penetrate a septum of the canister and cause the gas within the canister to flow through the first chamber around the canister, and into the second chamber. The injector module includes a piston slidably disposed within an agent chamber and coupled to the distal end of the plunger such that, when the plunger moves from a retracted position to an extended position, the piston is advanced within the agent chamber to deliver an agent therein into a patient's body.

10. 发明授权

US11701254B2 Soft tip cannula with retractable tip protector 有权
公开(公告)号：US11701254B2
公开(公告)日：2023-07-18
申请号：US17100845
申请日：2020-11-21
申请人： ALTAVIZ, LLC
发明人： Jack R. Auld , Matthew Flowers , Tammo Heeren , Hien Nguyen , John C. Huculak , Eric Anderfaas
IPC分类号： A61F9/00 , A61M5/32 , A61M5/34
CPC分类号： A61F9/0008 , A61M5/3202 , A61M5/3204 , A61M5/3286 , A61M5/3293 , A61M5/343 , A61M5/347 , A61M5/348 , A61M2205/0216
摘要： Injector devices and methods for using them to deliver medicament into a patient's body, e.g., sub-retinally within an eye, are provided. The injector includes an injector cannula having a soft injector tip. A retractable tip protector tube is slidably disposed on the flow cannula between an extended position in which the tip protector tube covers the entire injector tip, and a retracted position in which the tip protector tube is retracted proximally thereby exposing at least part of the injector tip. Accordingly, the tip protector tube protects the injector tip from being damaged while advancing the injector tip to a target injection site.

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