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1. 发明申请

US20100027007A1 SYSTEMS AND METHODS FOR A MULTIPLE ANGLE LIGHT SCATTERING (MALS) INSTRUMENT HAVING TWO-DIMENSIONAL DETECTOR ARRAY 失效
标题翻译：具有两维探测器阵列的多角度散射（MALS）仪器的系统和方法
公开(公告)号：US20100027007A1
公开(公告)日：2010-02-04
申请号：US12534780
申请日：2009-08-03
申请人： John A. Adams , Scott H. Bloom , Victor J. Chan , Kristina M. Crousore , Joseph S. Gottlieb , Oscar Hemberg , John J. Lyon , Brett A. Spivey
发明人： John A. Adams , Scott H. Bloom , Victor J. Chan , Kristina M. Crousore , Joseph S. Gottlieb , Oscar Hemberg , John J. Lyon , Brett A. Spivey
IPC分类号： G01N21/00
CPC分类号： G01N15/1459 , G01N15/1434 , G01N15/1463 , G01N15/147 , G01N15/1475 , G01N2015/0088
摘要： A particle detection system uses a reflective optic comprising a curved surface to detect high angle scattered light generated by a particle in a liquid medium, when a laser beam is incident on the particle. When the particles transit the laser beam, light is scattered in all directions and is described by MIE scattering theory for particles about the size of the wavelength of light and larger or Rayleigh Scattering when the particles are smaller than the wavelength of light. By using the reflective optic, the scattered light can be detected over angles that are greater than normally obtainable.
摘要翻译：当激光束入射到粒子上时，粒子检测系统使用包括弯曲表面的反射光学器件来检测由液体介质中的粒子产生的高角散射光。当粒子通过激光束时，光在所有方向上散射，并且当颗粒小于光的波长时，通过MIE散射理论对关于光的波长大小或Rayleigh散射的粒子的粒子进行描述。通过使用反射光学元件，可以在大于通常可获得的角度上检测散射光。

2. 发明申请

US20100007505A1 SYSTEMS AND METHODS FOR DETECTING NORMAL LEVELS OF BACTERIA IN WATER USING A MULTIPLE ANGLE LIGHT SCATTERING (MALS) INSTRUMENT 失效
标题翻译：使用多角度散射（MALS）仪器检测水中细菌的正常水平的系统和方法
公开(公告)号：US20100007505A1
公开(公告)日：2010-01-14
申请号：US12483203
申请日：2009-06-11
申请人： John A. Adams , Kristina M. Crousore , Cherish K. Teters , John P. Ricardi , David L. McCarty , Michael P. Tutrow
发明人： John A. Adams , Kristina M. Crousore , Cherish K. Teters , John P. Ricardi , David L. McCarty , Michael P. Tutrow
IPC分类号： G08B21/00 , G01N33/48 , G01N21/00
CPC分类号： G01N33/1893 , G01N15/1459 , G01N15/1463 , G01N21/53 , G01N2015/0088 , G01N2015/0238
摘要： A particle detection system to identify and classify particles is programmed to capture digitized images of the particle generated by directing a light source through a fluid that includes the particle. The particle scatters the light and the scattered light is detected using a detector. The detector creates a digital signal corresponding to the particle, which is used by the system to generate Bio-Optical Signature. This Bio-Optical Signature can then be used to classify the event, or particle. Count rate and trends of the classified particles are monitored to detect a change that is representative of the overall health safety of the water or by knowing the levels of bacteria in process water, such as Reverse Osmosis (RO) feed water, reject brine, and product water, the operator may better monitor the life and condition of the RO membrane.
摘要翻译：用于识别和分类粒子的粒子检测系统被编程以捕获通过将光源引导通过包括粒子的流体而产生的粒子的数字化图像。颗粒散射光，并使用检测器检测散射光。检测器产生对应于粒子的数字信号，该数字信号被系统用于生成生物光学签名。然后可以使用该生物光学签名对事件或粒子进行分类。监测分类颗粒的计数率和趋势，以检测代表水的整体健康安全性的变化或通过了解工艺用水中的细菌水平，例如反渗透（RO）给水，拒收盐水和产品水，操作者可以更好地监测RO膜的使用寿命和状况。

3. 发明申请

US20120287435A1 AUTOMATIC DILUTION FOR MULTIPLE ANGLE LIGHT SCATTERING (MALS) INSTRUMENT 审中-公开
标题翻译：多角度散射（MALS）仪器的自动曝光
公开(公告)号：US20120287435A1
公开(公告)日：2012-11-15
申请号：US13106779
申请日：2011-05-12
申请人： John A. Adams , Steven Stephenson
发明人： John A. Adams , Steven Stephenson
IPC分类号： G01N21/00
CPC分类号： G01N21/51 , G01N1/38 , G01N15/1429 , G01N2021/4707
摘要： A method for detecting and identifying a particle in a liquid, the system comprises controlling the provisioning of a water sample using a computer controlled metering pump; mixing the water sample with particle free filtered water to provide a diluted water sample when required; at the end of a measurement interval, determining a Total Counts Per Minute (TCPM) for the diluted water sample; determining an additional counts per minute from the sample (SCPM) for the diluted water sample; if the SCPM is greater then a Lower Optimum count Rate (LOCR) and less than a Upper Optimum Count Rate (UOCR), then setting a dilution ratio (DR); and correcting an events classification based on the DR.
摘要翻译：一种用于检测和识别液体中的颗粒的方法，所述系统包括使用计算机控制计量泵来控制供水样品; 将水样品与无颗粒过滤水混合，以便在需要时提供稀释的水样品; 在测量间隔结束时，确定稀释水样品的总计数（TCPM）; 从样品（SCPM）确定稀释水样品的每分钟附加计数; 如果SCPM大于较低最优计数率（LOCR），小于上最佳计数率（UOCR），则设置稀释比（DR）; 以及基于DR来校正事件分类。

4. 发明授权

US08085399B2 Systems and methods for a multiple angle light scattering (MALS) instrument having two-dimensional detector array 失效
标题翻译：具有二维检测器阵列的多角度散射（MALS）仪器的系统和方法
公开(公告)号：US08085399B2
公开(公告)日：2011-12-27
申请号：US12534780
申请日：2009-08-03
申请人： John A. Adams , Scott H. Bloom , Victor J. Chan , Kristina M. Crousore , Joseph S. Gottlieb , Oscar Hemberg , John J. Lyon , Brett A. Spivey
发明人： John A. Adams , Scott H. Bloom , Victor J. Chan , Kristina M. Crousore , Joseph S. Gottlieb , Oscar Hemberg , John J. Lyon , Brett A. Spivey
IPC分类号： G01N21/00
CPC分类号： G01N15/1459 , G01N15/1434 , G01N15/1463 , G01N15/147 , G01N15/1475 , G01N2015/0088
摘要： A particle detection system uses a reflective optic comprising a curved surface to detect high angle scattered light generated by a particle in a liquid medium, when a laser beam is incident on the particle. When the particles transit the laser beam, light is scattered in all directions and is described by MIE scattering theory for particles about the size of the wavelength of light and larger or Rayleigh Scattering when the particles are smaller than the wavelength of light. By using the reflective optic, the scattered light can be detected over angles that are greater than normally obtainable.
摘要翻译：当激光束入射到粒子上时，粒子检测系统使用包括弯曲表面的反射光学器件来检测由液体介质中的粒子产生的高角散射光。当粒子通过激光束时，光在所有方向上散射，并且当颗粒小于光的波长时，通过MIE散射理论对关于光的波长大小或Rayleigh散射的粒子的粒子进行描述。通过使用反射光学元件，可以在大于通常可获得的角度上检测散射光。

5. 发明授权

US07616311B2 Systems and methods for a multiple angle light scattering (MALS) instrument having two-dimensional detector array 失效
标题翻译：具有二维检测器阵列的多角度散射（MALS）仪器的系统和方法
公开(公告)号：US07616311B2
公开(公告)日：2009-11-10
申请号：US11453278
申请日：2006-06-13
申请人： John A. Adams , Scott H. Bloom , Victor J. Chan , Kristina M. Crousore , Joseph S. Gottlieb , Oscar Hemberg , John J. Lyon , Brett A. Spivey
发明人： John A. Adams , Scott H. Bloom , Victor J. Chan , Kristina M. Crousore , Joseph S. Gottlieb , Oscar Hemberg , John J. Lyon , Brett A. Spivey
IPC分类号： G01N21/00
CPC分类号： G01N15/1459 , G01N15/1434 , G01N15/1463 , G01N15/147 , G01N15/1475 , G01N2015/0088
摘要： A particle detection system uses a reflective optic comprising a curved surface to detect high angle scattered light generated by a particle in a liquid medium, when a laser beam is incident on the particle. When the particles transit the laser beam, light is scattered in all directions and is described by MIE scattering theory for particles about the size of the wavelength of light and larger or Rayleigh Scattering when the particles are smaller than the wavelength of light. By using the reflective optic, the scattered light can be detected over angles that are greater than normally obtainable.
摘要翻译：当激光束入射到粒子上时，粒子检测系统使用包括弯曲表面的反射光学器件来检测由液体介质中的粒子产生的高角散射光。当粒子通过激光束时，光在所有方向上散射，并且当颗粒小于光的波长时，通过MIE散射理论对关于光的波长大小或Rayleigh散射的粒子的粒子进行描述。通过使用反射光学元件，可以在大于通常可获得的角度上检测散射光。

6. 发明授权

US08243272B2 Systems and methods for detecting normal levels of bacteria in water using a multiple angle light scattering (MALS) instrument 失效
标题翻译：使用多角度光散射（MALS）仪器检测水中细菌的正常水平的系统和方法
公开(公告)号：US08243272B2
公开(公告)日：2012-08-14
申请号：US12868654
申请日：2010-08-25
申请人： John A. Adams
发明人： John A. Adams
IPC分类号： G01N21/00
CPC分类号： G01N15/147 , G01N21/53 , G01N33/1893 , G01N2015/0088 , G01N2015/1477 , G01N2015/1497
摘要： A particle detection system uses a camera to produce a picture based on the scattered light generated by a particle in a liquid medium, when a laser beam is incident on the particle. These pictures are then automatically analyzed through the use of a processing system (e.g., a computer). The processing system is configured to record the forward scattering intensity (e.g., amplitude) and the picture of the scattered light rays to generate a classification of the particle causing the scattering. Count rate and trends of the classified particles are monitored to detect a change that is representative of the overall health safety of the water or by knowing the levels of bacteria in process water, such as Reverse Osmosis (RO) feed water, reject brine, and product water, the operator may better monitor the life and condition of the RO membrane.
摘要翻译：当激光束入射到粒子上时，粒子检测系统使用相机基于由液体介质中的粒子产生的散射光来产生图像。然后通过使用处理系统（例如，计算机）自动分析这些图像。处理系统被配置为记录散射光线的前向散射强度（例如振幅）和图像，以产生导致散射的粒子的分类。监测分类颗粒的计数率和趋势，以检测代表水的整体健康安全性的变化或通过了解工艺用水中的细菌水平，例如反渗透（RO）给水，拒收盐水和产品水，操作者可以更好地监测RO膜的使用寿命和状况。

7. 发明申请

US20110066382A1 SYSTEMS AND METHODS FOR DETECTING NORMAL LEVELS OF BACTERIA IN WATER USING A MULTIPLE ANGLE LIGHT SCATTERING (MALS) INSTRUMENT 失效
标题翻译：使用多角度散射（MALS）仪器检测水中细菌的正常水平的系统和方法
公开(公告)号：US20110066382A1
公开(公告)日：2011-03-17
申请号：US12868654
申请日：2010-08-25
申请人： John A. Adams
发明人： John A. Adams
IPC分类号： G06F19/00 , G01N21/47
CPC分类号： G01N15/147 , G01N21/53 , G01N33/1893 , G01N2015/0088 , G01N2015/1477 , G01N2015/1497
摘要： A particle detection system uses a camera to produce a picture based on the scattered light generated by a particle in a liquid medium, when a laser beam is incident on the particle. These pictures are then automatically analyzed through the use of a processing system (e.g., a computer). The processing system is configured to record the forward scattering intensity (e.g., amplitude) and the picture of the scattered light rays to generate a classification of the particle causing the scattering. Count rate and trends of the classified particles are monitored to detect a change that is representative of the overall health safety of the water or by knowing the levels of bacteria in process water, such as Reverse Osmosis (RO) feed water, reject brine, and product water, the operator may better monitor the life and condition of the RO membrane.
摘要翻译：当激光束入射到粒子上时，粒子检测系统使用相机基于由液体介质中的粒子产生的散射光来产生图像。然后通过使用处理系统（例如，计算机）自动分析这些图像。处理系统被配置为记录散射光线的前向散射强度（例如振幅）和图像，以产生导致散射的粒子的分类。监测分类颗粒的计数率和趋势，以检测代表水的整体健康安全性的变化或通过了解工艺用水中的细菌水平，例如反渗透（RO）给水，拒收盐水和产品水，操作者可以更好地监测RO膜的使用寿命和状况。

8. 发明授权

US08134704B2 Systems and methods for detecting normal levels of bacteria in water using a multiple angle light scattering (MALS) instrument 失效
标题翻译：使用多角度光散射（MALS）仪器检测水中细菌的正常水平的系统和方法
公开(公告)号：US08134704B2
公开(公告)日：2012-03-13
申请号：US12483203
申请日：2009-06-11
申请人： John A. Adams , Kristina M. Crousore , Cherish K. Teters , John P. Ricardi , David L. McCarty , Michael P. Tutrow
发明人： John A. Adams , Kristina M. Crousore , Cherish K. Teters , John P. Ricardi , David L. McCarty , Michael P. Tutrow
IPC分类号： G01N15/02 , G01N21/00
CPC分类号： G01N33/1893 , G01N15/1459 , G01N15/1463 , G01N21/53 , G01N2015/0088 , G01N2015/0238
摘要： A particle detection system to identify and classify particles is programmed to capture digitized images of the particle generated by directing a light source through a fluid that includes the particle. The particle scatters the light and the scattered light is detected using a detector. The detector creates a digital signal corresponding to the particle, which is used by the system to generate Bio-Optical Signature. This Bio-Optical Signature can then be used to classify the event, or particle. Count rate and trends of the classified particles are monitored to detect a change that is representative of the overall health safety of the water or by knowing the levels of bacteria in process water, such as Reverse Osmosis (RO) feed water, reject brine, and product water, the operator may better monitor the life and condition of the RO membrane.
摘要翻译：用于识别和分类粒子的粒子检测系统被编程以捕获通过将光源引导通过包括粒子的流体而产生的粒子的数字化图像。颗粒散射光，并使用检测器检测散射光。检测器产生对应于粒子的数字信号，该数字信号被系统用于生成生物光学签名。然后可以使用该生物光学签名对事件或粒子进行分类。监测分类颗粒的计数率和趋势，以检测代表水的整体健康安全性的变化或通过了解工艺用水中的细菌水平，例如反渗透（RO）给水，拒收盐水和产品水，操作者可以更好地监测RO膜的使用寿命和状况。

9. 发明授权

US07688443B2 Multipulse agile laser source for real time spark spectrochemical hazard analysis 失效
标题翻译：多脉冲敏捷激光源实时火花光谱危害分析
公开(公告)号：US07688443B2
公开(公告)日：2010-03-30
申请号：US11548678
申请日：2006-10-11
申请人： Harry Rieger
发明人： Harry Rieger
IPC分类号： G01J3/30
CPC分类号： G01J3/10 , G01J3/443 , G01N21/718 , H01S3/08054 , H01S3/10038 , H01S3/10046 , H01S3/107 , H01S3/1103 , H01S3/115 , H01S3/127 , H01S3/2316 , H01S3/2341 , H01S3/2383
摘要： A sample analysis system comprises a laser unit and a spectrometer unit. The laser unit emits a first laser pulse and a second laser pulse towards the sample with a pulse separation time of between about 1 microsecond to 20 microseconds. The laser unit includes an oscillator unit which is configured to generate the first laser pulse and the second laser pulse. A pre-amplifier unit is configured to receive the first laser pulse and the second laser pulse and increase the energy levels of each pulse prior to the pulses being emitted from the laser unit. The spectrometer unit captures emissions generated by the sample after the sample is stuck by the first and second laser pulses and identifies the elemental constituents of the sample using the emissions.
摘要翻译：样品分析系统包括激光单元和光谱仪单元。激光单元以约1微秒至20微秒之间的脉冲间隔时间向样品发射第一激光脉冲和第二激光脉冲。激光单元包括被配置为产生第一激光脉冲和第二激光脉冲的振荡器单元。预放大器单元被配置为在从激光单元发射脉冲之前接收第一激光脉冲和第二激光脉冲并增加每个脉冲的能级。在样品被第一和第二激光脉冲粘附之后，光谱仪单元捕获样品产生的发射，并使用排放物识别样品的元素成分。

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