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    • 5. 发明申请
    • pH SENSOR INTEGRATION TO SINGLE USE BIOREACTOR/MIXER
    • pH传感器集成到单个使用的生物反应器/混合器
    • US20120178153A1
    • 2012-07-12
    • US13325254
    • 2011-12-14
    • Chang-Dong FengBarry W. BentonDave AndersonFong S. YangWayne B. Wood
    • Chang-Dong FengBarry W. BentonDave AndersonFong S. YangWayne B. Wood
    • C12M1/00
    • C12M23/14C12M41/26C12M41/32C12M41/34
    • A pH sensing bioreaction system is provided. The system includes a bioreaction container having a plastic wall and a pH sensor attached to the plastic wall. The pH sensor includes a sensor body having a flange that is sealingly attached to the plastic wall. The sensor body has a reference electrolyte therein and a first sensing element disposed in the reference electrolyte. The first sensing element is configured to contact both the reference electrolyte and a sample solution inside the bioreaction container. A second sensing element is positionable into an interior of the bioreaction container. The pH sensor has a plurality of configurations that include a booted configuration in which at least one sensing element is isolated from the interior of the bioreaction container, and a service configuration in which the at least one sensing element is fluidically coupled to the interior of the bioreaction container.
    • 提供pH感应生物反应系统。 该系统包括具有塑料壁和附着在塑料壁上的pH传感器的生物反应容器。 pH传感器包括具有密封地附接到塑料壁的凸缘的传感器本体。 传感器主体中具有参考电解质,并且设置在参考电解质中的第一感测元件。 第一感测元件被配置为接触生物反应容器内的参考电解质和样品溶液。 第二感测元件可定位到生物反应容器的内部。 pH传感器具有多个构造,其包括引导构造,其中至少一个感测元件与生物反应容器的内部隔离,并且其中至少一个感测元件流体地联接到生物反应容器的内部的服务构造 生物反应容器。
    • 8. 发明授权
    • pH sensor integration to single use bioreactor/mixer
    • pH传感器集成到单次生物反应器/混合器
    • US08900855B2
    • 2014-12-02
    • US13325254
    • 2011-12-14
    • Chang-Dong FengBarry W. BentonDave AndersonFong S. YangWayne B. Wood
    • Chang-Dong FengBarry W. BentonDave AndersonFong S. YangWayne B. Wood
    • C12M1/00C12M3/00C12M1/12C12M1/26C12C1/15C12C7/06C12M1/34
    • C12M23/14C12M41/26C12M41/32C12M41/34
    • A pH sensing bioreaction system is provided. The system includes a bioreaction container having a plastic wall and a pH sensor attached to the plastic wall. The pH sensor includes a sensor body having a flange that is sealingly attached to the plastic wall. The sensor body has a reference electrolyte therein and a first sensing element disposed in the reference electrolyte. The first sensing element is configured to contact both the reference electrolyte and a sample solution inside the bioreaction container. A second sensing element is positionable into an interior of the bioreaction container. The pH sensor has a plurality of configurations that include a booted configuration in which at least one sensing element is isolated from the interior of the bioreaction container, and a service configuration in which the at least one sensing element is fluidically coupled to the interior of the bioreaction container.
    • 提供pH感应生物反应系统。 该系统包括具有塑料壁和附着在塑料壁上的pH传感器的生物反应容器。 pH传感器包括具有密封地附接到塑料壁的凸缘的传感器本体。 传感器主体中具有参考电解质,并且设置在参考电解质中的第一感测元件。 第一感测元件被配置为接触生物反应容器内的参考电解质和样品溶液。 第二感测元件可定位到生物反应容器的内部。 pH传感器具有多个构造,其包括引导构造,其中至少一个感测元件与生物反应容器的内部隔离,并且其中至少一个感测元件流体地联接到生物反应容器的内部的服务构造 生物反应容器。
    • 10. 发明授权
    • Insulated core electrode for pH sensor
    • PH传感器用绝缘芯电极
    • US5221456A
    • 1993-06-22
    • US781106
    • 1991-10-22
    • Barry W. BentonLawrence R. MajerusDonald R. RuttFred C. SittlerAdrian C. Toy
    • Barry W. BentonLawrence R. MajerusDonald R. RuttFred C. SittlerAdrian C. Toy
    • G01N27/30G01N27/333
    • G01N27/333
    • A pH sensor has a core of an electrochemically inert insulating or semi-conductive material, and is coated with an electrically conductive, electrochemically sensitive coating. The preferred core is insulating and made of alumina, with a thin coating of iridium oxide deposited over at least a portion of the outer surface of the core. The coating is carried to a surface remote from the sensing surface and is used for making electrically conductive connections that lead to remote circuitry. The core is made in a form that can be supported and held in an insulating, electrochemically inert, deformable material that is sealed around the outer surface of the coating on the core to prevent leakage of chemicals being sensed. The body also permits sealing quite easily onto access ports on which the sensor housing is mounted. Various connections to the electrode coating can be made quite easily to provide for a unique sensor assembly.
    • pH传感器具有电化学惰性绝缘或半导体材料的芯,并且涂覆有导电的电化学敏感性涂层。 优选的芯是绝缘的,由氧化铝制成,在芯的外表面的至少一部分上沉积有氧化铱的薄涂层。 涂层被传送到远离感测表面的表面,并用于制造导电远程电路的导电连接。 芯部制成的形式可以被支撑并保持在绝缘的,电化学惰性的可变形的材料中,该材料围绕芯上的涂层的外表面被密封,以防止感测到的化学物质泄漏。 车身还允许密封很容易到安装传感器外壳的进入口上。 可以非常容易地形成与电极涂层的各种连接以提供独特的传感器组件。