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1. 发明授权

US08900855B2 pH sensor integration to single use bioreactor/mixer 有权
标题翻译： pH传感器集成到单次生物反应器/混合器
公开(公告)号：US08900855B2
公开(公告)日：2014-12-02
申请号：US13325254
申请日：2011-12-14
申请人： Chang-Dong Feng , Barry W. Benton , Dave Anderson , Fong S. Yang , Wayne B. Wood
发明人： Chang-Dong Feng , Barry W. Benton , Dave Anderson , Fong S. Yang , Wayne B. Wood
IPC分类号： C12M1/00 , C12M3/00 , C12M1/12 , C12M1/26 , C12C1/15 , C12C7/06 , C12M1/34
CPC分类号： C12M23/14 , C12M41/26 , C12M41/32 , C12M41/34
摘要： A pH sensing bioreaction system is provided. The system includes a bioreaction container having a plastic wall and a pH sensor attached to the plastic wall. The pH sensor includes a sensor body having a flange that is sealingly attached to the plastic wall. The sensor body has a reference electrolyte therein and a first sensing element disposed in the reference electrolyte. The first sensing element is configured to contact both the reference electrolyte and a sample solution inside the bioreaction container. A second sensing element is positionable into an interior of the bioreaction container. The pH sensor has a plurality of configurations that include a booted configuration in which at least one sensing element is isolated from the interior of the bioreaction container, and a service configuration in which the at least one sensing element is fluidically coupled to the interior of the bioreaction container.
摘要翻译：提供pH感应生物反应系统。该系统包括具有塑料壁和附着在塑料壁上的pH传感器的生物反应容器。 pH传感器包括具有密封地附接到塑料壁的凸缘的传感器本体。传感器主体中具有参考电解质，并且设置在参考电解质中的第一感测元件。第一感测元件被配置为接触生物反应容器内的参考电解质和样品溶液。第二感测元件可定位到生物反应容器的内部。 pH传感器具有多个构造，其包括引导构造，其中至少一个感测元件与生物反应容器的内部隔离，并且其中至少一个感测元件流体地联接到生物反应容器的内部的服务构造生物反应容器。

2. 发明申请

US20120178153A1 pH SENSOR INTEGRATION TO SINGLE USE BIOREACTOR/MIXER 有权
标题翻译： pH传感器集成到单个使用的生物反应器/混合器
公开(公告)号：US20120178153A1
公开(公告)日：2012-07-12
申请号：US13325254
申请日：2011-12-14
申请人： Chang-Dong Feng , Barry W. Benton , Dave Anderson , Fong S. Yang , Wayne B. Wood
发明人： Chang-Dong Feng , Barry W. Benton , Dave Anderson , Fong S. Yang , Wayne B. Wood
IPC分类号： C12M1/00
CPC分类号： C12M23/14 , C12M41/26 , C12M41/32 , C12M41/34
摘要： A pH sensing bioreaction system is provided. The system includes a bioreaction container having a plastic wall and a pH sensor attached to the plastic wall. The pH sensor includes a sensor body having a flange that is sealingly attached to the plastic wall. The sensor body has a reference electrolyte therein and a first sensing element disposed in the reference electrolyte. The first sensing element is configured to contact both the reference electrolyte and a sample solution inside the bioreaction container. A second sensing element is positionable into an interior of the bioreaction container. The pH sensor has a plurality of configurations that include a booted configuration in which at least one sensing element is isolated from the interior of the bioreaction container, and a service configuration in which the at least one sensing element is fluidically coupled to the interior of the bioreaction container.
摘要翻译：提供pH感应生物反应系统。该系统包括具有塑料壁和附着在塑料壁上的pH传感器的生物反应容器。 pH传感器包括具有密封地附接到塑料壁的凸缘的传感器本体。传感器主体中具有参考电解质，并且设置在参考电解质中的第一感测元件。第一感测元件被配置为接触生物反应容器内的参考电解质和样品溶液。第二感测元件可定位到生物反应容器的内部。 pH传感器具有多个构造，其包括引导构造，其中至少一个感测元件与生物反应容器的内部隔离，并且其中至少一个感测元件流体地联接到生物反应容器的内部的服务构造生物反应容器。

3. 发明申请

US20100084285A1 PROCESS ANALYTIC SENSOR WITH MOISTURE-SCAVENGING ELECTRODE BACKFILL 审中-公开
标题翻译：具有水分扫描电极背景的工艺分析传感器
公开(公告)号：US20100084285A1
公开(公告)日：2010-04-08
申请号：US12246627
申请日：2008-10-07
申请人： Barry W. Benton , Chang-Dong Feng
发明人： Barry W. Benton , Chang-Dong Feng
IPC分类号： G01N27/26 , G01N27/30 , G01N27/36 , F16J15/14
CPC分类号： G01N27/4035
摘要： A process analytic sensor for sensing a characteristic of a process fluid is disclosed. The sensor includes a housing including a sensing portion having an electrical characteristic that varies with a characteristic of the process fluid. An instrument cable has at least one electrical conductor. An electrode connection space is located within the housing and the at least one electrical conductor is electrically coupled to a respective conductor of a sensing element of the sensing portion. A fill material is disposed in the electrode connection space. The fill material cures through exposure to moisture and the fill material is uncured and sealed within the electrode connection space.
摘要翻译：公开了一种用于感测工艺流体特性的工艺分析传感器。该传感器包括壳体，其包括具有根据过程流体的特性而变化的电特性的感测部分。仪器电缆至少有一个电导线。电极连接空间位于壳体内，并且至少一个电导体电耦合到感测部分的感测元件的相应导体。填充材料设置在电极连接空间中。填充材料通过暴露于水分而固化，并且填充材料未固化并密封在电极连接空间内。

4. 发明授权

US09029130B2 Unitary plastic conductivity sensor 有权
标题翻译：单一塑料电导率传感器
公开(公告)号：US09029130B2
公开(公告)日：2015-05-12
申请号：US13325265
申请日：2011-12-14
申请人： Chang-Dong Feng , Barry W. Benton
发明人： Chang-Dong Feng , Barry W. Benton
IPC分类号： C12M1/34 , C12M3/00 , C12M1/00 , C12M1/36 , C12M1/38 , C12N9/00 , C12N11/00 , G01N27/07 , G01N27/30
CPC分类号： G01N27/07 , G01N27/30
摘要： A contacting-type conductivity sensor includes an electrically-insulative plastic body and a plurality of electrodes. The plurality of conductive electrodes is disposed in the plastic body. Each electrode is constructed of plastic and fused with the electrically-insulative plastic body. A method of manufacturing the conductivity sensor is provided along with a single-use bioreactor employing the sensor.
摘要翻译：接触型电导率传感器包括电绝缘塑料体和多个电极。多个导电电极设置在塑料体中。每个电极由塑料构成，并与电绝缘塑料体熔合。与使用该传感器的一次性生物反应器一起提供制造电导率传感器的方法。

5. 发明申请

US20120178151A1 UNITARY PLASTIC CONDUCTIVITY SENSOR 有权
标题翻译：单位塑料电导率传感器
公开(公告)号：US20120178151A1
公开(公告)日：2012-07-12
申请号：US13325265
申请日：2011-12-14
申请人： Chang-Dong Feng , Barry W. Benton
发明人： Chang-Dong Feng , Barry W. Benton
IPC分类号： G01R27/28 , B29C45/14 , C12M1/34
CPC分类号： G01N27/07 , G01N27/30
摘要： A contacting-type conductivity sensor includes an electrically-insulative plastic body and a plurality of electrodes. The plurality of conductive electrodes is disposed in the plastic body. Each electrode is constructed of plastic and fused with the electrically-insulative plastic body. A method of manufacturing the conductivity sensor is provided along with a single-use bioreactor employing the sensor.
摘要翻译：接触型电导率传感器包括电绝缘塑料体和多个电极。多个导电电极设置在塑料体中。每个电极由塑料构成，并与电绝缘塑料体熔合。与使用该传感器的一次性生物反应器一起提供制造电导率传感器的方法。

6. 发明申请

US20080283399A1 POTENTIOMETRIC PROCESS ANALYTIC SENSOR WITH ISOLATED TEMPERATURE SENSOR 审中-公开
标题翻译：具有隔离温度传感器的电位分析过程分析传感器
公开(公告)号：US20080283399A1
公开(公告)日：2008-11-20
申请号：US12120619
申请日：2008-05-14
申请人： Chang-Dong Feng , Barry W. Benton
发明人： Chang-Dong Feng , Barry W. Benton
IPC分类号： G01N27/26
CPC分类号： G01N27/36 , G01N27/4035
摘要： A sensor for analyzing a liquid sample is provided. The sensor includes a sensor body defining a chamber therein. A sensing cell is disposed within the chamber and is adapted to contact the sample solution. The sensing cell has a sensing cell fill solution therein, and a sensing electrode disposed within the sensing cell fill solution. A reference fill solution is disposed within the sensor body. A reference junction is arranged to contact the reference fill solution and the sample solution. A temperature sensitive device is disposed within the body and is configured to provide a temperature sensitive device output. A reference electrode is disposed within the sensor body in contact with the reference fill solution. A solution ground electrode is disposed within the sensor body and spaced from the reference electrode.
摘要翻译：提供了用于分析液体样品的传感器。传感器包括在其中限定室的传感器主体。感测单元设置在室内并且适于接触样品溶液。感测单元在其中具有感测单元填充溶液，以及设置在感测单元填充溶液内的感测电极。参考填充溶液设置在传感器主体内。参考连接点被布置成接触参考填充溶液和样品溶液。温度敏感设备设置在主体内并且被配置为提供温度敏感的设备输出。参考电极设置在与参考填充溶液接触的传感器主体内。溶液接地电极设置在传感器主体内并与参考电极间隔开。

7. 发明申请

US20080237042A1 High purity water pH sensor with shielded flowing liquid junction 有权
标题翻译：高纯度水pH传感器，带有屏蔽流动液体接头
公开(公告)号：US20080237042A1
公开(公告)日：2008-10-02
申请号：US11904620
申请日：2007-09-27
申请人： Chang-Dong Feng , Beth M. Covey , Wayne B. Wood
发明人： Chang-Dong Feng , Beth M. Covey , Wayne B. Wood
IPC分类号： G01N27/26
CPC分类号： G01N27/36 , G01N27/401
摘要： A pH sensor is provided. The pH sensor includes a body, a glass electrode, a reference electrode and a solution ground. The glass electrode is disposed on the body to contact a liquid sample. The reference electrode has a reference fill solution disposed within the body. The solution ground electrode is operably coupled to the body and has a portion of the solution ground electrode that is disposed within a harbor such that a portion of the solution ground electrode is configured to contact the liquid sample. The body has a passageway that extends from the reference fill solution to an aperture proximate the liquid sample.
摘要翻译：提供pH传感器。 pH传感器包括主体，玻璃电极，参比电极和溶液接地。玻璃电极设置在身体上以接触液体样品。参考电极具有设置在体内的参考填充溶液。溶液接地电极可操作地耦合到主体并且具有设置在港口内的溶液接地电极的一部分，使得溶液接地电极的一部分被配置为接触液体样品。主体具有从参考填充溶液延伸到靠近液体样品的孔的通道。

8. 发明授权

US07837847B2 High purity water pH sensor with shielded flowing liquid junction 有权
标题翻译：高纯度水pH传感器，带有屏蔽流动液体接头
公开(公告)号：US07837847B2
公开(公告)日：2010-11-23
申请号：US11904620
申请日：2007-09-27
申请人： Chang-Dong Feng , Beth M. Covey , Wayne B. Wood
发明人： Chang-Dong Feng , Beth M. Covey , Wayne B. Wood
IPC分类号： G01N27/30 , G01N27/401 , G01N27/403 , G01N27/36
CPC分类号： G01N27/36 , G01N27/401
摘要： A pH sensor is provided. The pH sensor includes a body, a glass electrode, a reference electrode and a solution ground. The glass electrode is disposed on the body to contact a liquid sample. The reference electrode has a reference fill solution disposed within the body. The solution ground electrode is operably coupled to the body and has a portion of the solution ground electrode that is disposed within a harbor such that a portion of the solution ground electrode is configured to contact the liquid sample. The body has a passageway that extends from the reference fill solution to an aperture proximate the liquid sample.
摘要翻译：提供pH传感器。 pH传感器包括主体，玻璃电极，参比电极和溶液接地。玻璃电极设置在身体上以接触液体样品。参考电极具有设置在体内的参考填充溶液。溶液接地电极可操作地耦合到主体并且具有设置在港口内的溶液接地电极的一部分，使得溶液接地电极的一部分被配置为接触液体样品。主体具有从参考填充溶液延伸到靠近液体样品的孔的通道。

9. 发明授权

US07790006B2 Free chlorine sensor 有权
标题翻译：游离氯传感器
公开(公告)号：US07790006B2
公开(公告)日：2010-09-07
申请号：US10939866
申请日：2004-09-13
申请人： Chang-Dong Feng , Jishou Xu , Joshua Steven Garretson
发明人： Chang-Dong Feng , Jishou Xu , Joshua Steven Garretson
IPC分类号： G01N27/26
CPC分类号： G01N27/404 , G01N27/4045 , G01N33/0049
摘要： A free chlorine measurement system and sensor are provided. In accordance with one aspect of the invention, the sensor has a porous working electrode disposed in an electrolyte proximate a porous membrane. The membrane allows free chlorine therethrough where it is reduced and generates a current. The current is related to the free chlorine concentration. The internal electrolyte solution is pH stabilized with a long-term pH stabilizer that has a solubility in water at room temperature between about 1.2 moles/liter and about 0.001 moles/liter. The stabilizer can be an acid or a base depending on whether the pH is to be stabilized at a relatively low value or a relatively high value respectively.
摘要翻译：提供了一个游离氯测量系统和传感器。根据本发明的一个方面，传感器具有多孔工作电极，其设置在靠近多孔膜的电解质中。膜允许通过其中的游离氯被还原并产生电流。电流与游离氯浓度有关。内部电解质溶液用长期的pH稳定剂进行pH稳定化，其在室温下在水中的溶解度在约1.2摩尔/升至约0.001摩尔/升之间。稳定剂可以是酸或碱，这取决于pH是否稳定在相对较低的值或相对较高的值。

10. 发明授权

US07323887B2 Conductivity sensor and manufacturing method therefor 失效
标题翻译：电导传感器及其制造方法
公开(公告)号：US07323887B2
公开(公告)日：2008-01-29
申请号：US11396403
申请日：2006-03-30
申请人： Chang-Dong Feng
发明人： Chang-Dong Feng
IPC分类号： G01R27/08 , G01N27/02 , G01N11/00
CPC分类号： C25D17/02 , C25D21/12 , G01N27/07 , G01R27/22
摘要： A contacting-type conductivity sensor includes a plurality of electrodes disposed on a distal surface of a substrate. The substrate includes a plurality of vias through which electrical interconnection to the electrodes is accomplished. The conductivity sensor can employ two or four electrodes and may have a temperature sensitive element disposed on the distal surface. The electrodes may be patterned or otherwise deposited using semiconductor processing techniques.
摘要翻译：接触型电导率传感器包括设置在基板的远侧表面上的多个电极。衬底包括多个通孔，通过该通孔与电极实现电互连。电导率传感器可以使用两个或四个电极，并且可以具有设置在远端表面上的温度敏感元件。可以使用半导体处理技术将电极图案化或以其他方式沉积。

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