专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20170239259A1 ARYLOXY PHENOXY ACRYLIC COMPOUND HAVING HIF-1 INHIBITION ACTIVITY, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS AN ACTIVE INGREDIENT 审中-公开
公开(公告)号：US20170239259A1
公开(公告)日：2017-08-24
申请号：US14569201
申请日：2014-12-12
申请人： Kyeong LEE , Mi Sun WON , Hwan Mook KIM , Song Kyu PARK , Kiho LEE , Ki Hoon LEE , Chang Woo LEE , Jung Joon LEE , Kyung Sook CHUNG , Bo Kyung KIM , Yinglan JIN , Seung-hee LEE
发明人： Kyeong LEE , Mi Sun WON , Hwan Mook KIM , Song Kyu PARK , Kiho LEE , Ki Hoon LEE , Chang Woo LEE , Jung Joon LEE , Kyung Sook CHUNG , Bo Kyung KIM , Yinglan JIN , Seung-hee LEE
IPC分类号： A61K31/5375 , A61K31/167 , A61K31/196 , A61K31/40 , A61K31/34 , A61K9/08 , A61K31/417 , A61K9/00 , A61K9/14 , A61K9/20 , A61K9/48 , A61K31/24 , A61K31/4409
CPC分类号： A61K31/5375 , A61K9/0019 , A61K9/08 , A61K9/14 , A61K9/20 , A61K9/48 , A61K31/167 , A61K31/196 , A61K31/24 , A61K31/34 , A61K31/40 , A61K31/417 , A61K31/4409 , C07C233/07 , C07C235/28 , C07C311/16 , C07C311/46 , C07C317/40 , C07C2603/74 , C07D295/088
摘要： The present invention relates to a compound inhibiting HF-1 activity, a preparation method of the same, and a pharmaceutical composition comprising the same as an active ingredient. The compound of the present invention demonstrates anticancer activity not by non-selective cytotoxicity but by inhibiting the activity of HIF-1, the transcription factor playing an important role in cancer cell growth and metastasis.Accordingly, the compound or the pharmaceutically acceptable salt thereof according to the present invention inhibits HIF-1 activity, and therefore can be used as a therapeutic agent for solid tumors such as colon cancer, liver cancer, stomach cancer and breast cancer. In addition, the compound or the pharmaceutically acceptable salt thereof according to the present invention can be used as an active ingredient for a therapeutic agent for diabetic retinopathy or arthritis which may become worse when hypoxia-induced VEGF expression by HIF-1 increases.

2. 发明申请

US20100113538A1 N-HYDROXY-4- BENZAMIDINE 2 ETHANSULFONIC ACID SALT, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME 失效
标题翻译： N-羟基-4-苄基嘧啶2乙酸钠盐，其制备方法和包含其的药物组合物
公开(公告)号：US20100113538A1
公开(公告)日：2010-05-06
申请号：US12531807
申请日：2008-04-21
申请人： Jin Soo Lee , Soon Ki Cho , Seoung Kyoo Sung , Young Goo Jin , Jae Hoon Park , Bo Kyung Kim , Ja Hyun Cha , Eun Hee Cho , Jei Man Ryu
发明人： Jin Soo Lee , Soon Ki Cho , Seoung Kyoo Sung , Young Goo Jin , Jae Hoon Park , Bo Kyung Kim , Ja Hyun Cha , Eun Hee Cho , Jei Man Ryu
IPC分类号： A61K31/426 , C07D277/30 , A61P19/10 , A61P19/00 , A61P29/00 , A61P37/08
CPC分类号： C07D277/24
摘要： N-hydroxy-4-{5-[4-(5-isopropyl-2-methyl-1,3-thiazol-4-yl)phenoxy]pentoxy}benzamidine 2 ethansulfonic acid salt, a process for the preparation thereof, a pharmaceutical composition for preventing and treating osteoporosis, bone fractures or allergic inflammatory diseases, comprising the same, and an oral formulation for preventing and treating osteoporosis, bone fractures or allergic inflammatory diseases, comprising the same are described.
摘要翻译： N-羟基-4- {5- [4-（5-异丙基-2-甲基-1,3-噻唑-4-基）苯氧基]戊氧基}苄脒2乙磺酸盐，其制备方法，药物描述了用于预防和治疗骨质疏松症，骨折或过敏性炎性疾病的组合物，以及用于预防和治疗含有该组合物的骨质疏松症，骨折或过敏性炎性疾病的口服制剂。

3. 发明申请

US20080105909A1 Pixel circuit included in CMOS image sensors and associated methods 审中-公开
标题翻译： CMOS图像传感器和相关方法中包含的像素电路
公开(公告)号：US20080105909A1
公开(公告)日：2008-05-08
申请号：US11976658
申请日：2007-10-26
申请人： Seog-Heon Ham , Bo-Kyung Kim , Young-Cheol Chae , Gun-Hee Han
发明人： Seog-Heon Ham , Bo-Kyung Kim , Young-Cheol Chae , Gun-Hee Han
IPC分类号： H01L27/146 , H01L31/18
CPC分类号： H01L27/14689 , H01L27/14609 , H04N5/374
摘要： Example embodiments relate to a pixel structure of a CMOS image sensor, and associated methods. The pixel structure may include a substrate of a first-conductivity, a photodiode region of a second conductivity in the first-conductivity substrate, and a capacitor electrode on the second-conductivity photodiode region.
摘要翻译：示例实施例涉及CMOS图像传感器的像素结构以及相关方法。像素结构可以包括第一导电性基板的第一导电性基板，第二导电性的光电二极管区域和第二导电性光电二极管区域上的电容器电极。

4. 发明申请

US20080004041A1 Method and system for confirming location of lost wireless terminal 审中-公开
标题翻译：确认丢失的无线终端的位置的方法和系统
公开(公告)号：US20080004041A1
公开(公告)日：2008-01-03
申请号：US11649270
申请日：2007-01-04
申请人： Kyung-Hwan Ahn , Bo-Kyung Kim
发明人： Kyung-Hwan Ahn , Bo-Kyung Kim
IPC分类号： H04Q7/20
CPC分类号： H04W64/00 , H04W8/005 , H04W8/26
摘要： A method and apparatus for confirming a location of a lost wireless terminal is provided. A location confirmation request of the lost wireless terminal is received by a mobile communication network and identification information of the lost wireless terminal is transmitted to wireless terminals which have joined a location confirmation service of the lost wireless terminal. The wireless terminal which has joined the service searches for a wireless terminal corresponding to identification information coinciding with the identification information of the lost wireless terminal. The wireless terminal which has joined the service transmits a location of the previously searched for lost wireless terminal to the mobile communication network. The mobile communication network manages the received location of the lost wireless terminal.
摘要翻译：提供一种用于确认丢失的无线终端的位置的方法和装置。丢失的无线终端的位置确认请求由移动通信网络接收，丢失的无线终端的识别信息被发送到已经加入丢失的无线终端的位置确认服务的无线终端。已加入服务的无线终端搜索对应于与丢失的无线终端的识别信息相符的识别信息的无线终端。已经加入服务的无线终端将先前搜索到的丢失的无线终端的位置发送到移动通信网络。移动通信网络管理丢失的无线终端的接收位置。

5. 发明授权

US08940936B2 Aryloxy phenoxy acrylic compound having HIF-1 inhibition activity, method for preparing same, and pharmaceutical composition containing same as an active ingredient 有权
标题翻译：具有HIF-1抑制活性的芳氧基苯氧基丙烯酸化合物及其制备方法，以及含有它们作为活性成分的药物组合物
公开(公告)号：US08940936B2
公开(公告)日：2015-01-27
申请号：US13880642
申请日：2011-10-17
申请人： Kyeong Lee , Mi Sun Won , Hwan Mook Kim , Song Kyu Park , Kiho Lee , Ki Hoon Lee , Chang Woo Lee , Jung Joon Lee , Kyung Sook Chung , Bo Kyung Kim , Yinglan Jin , Seung-hee Lee
发明人： Kyeong Lee , Mi Sun Won , Hwan Mook Kim , Song Kyu Park , Kiho Lee , Ki Hoon Lee , Chang Woo Lee , Jung Joon Lee , Kyung Sook Chung , Bo Kyung Kim , Yinglan Jin , Seung-hee Lee
IPC分类号： C07C233/07 , A61K31/167 , C07C235/28 , C07C311/16 , C07D295/088
CPC分类号： A61K31/5375 , A61K9/0019 , A61K9/08 , A61K9/14 , A61K9/20 , A61K9/48 , A61K31/167 , A61K31/196 , A61K31/24 , A61K31/34 , A61K31/40 , A61K31/417 , A61K31/4409 , C07C233/07 , C07C235/28 , C07C311/16 , C07C311/46 , C07C317/40 , C07C2603/74 , C07D295/088
摘要： The present invention relates to a compound inhibiting HF-1 activity, a preparation method of the same, and a pharmaceutical composition comprising the same as an active ingredient. The compound of the present invention demonstrates anticancer activity not by non-selective cytotoxicity but by inhibiting the activity of HIF-1, the transcription factor playing an important role in cancer cell growth and metastasis. Accordingly, the compound or the pharmaceutically acceptable salt thereof according to the present invention inhibits HIF-1 activity, and therefore can be used as a therapeutic agent for solid tumors such as colon cancer, liver cancer, stomach cancer and breast cancer. In addition, the compound or the pharmaceutically acceptable salt thereof according to the present invention can be used as an active ingredient for a therapeutic agent for diabetic retinopathy or arthritis which may become worse when hypoxia-induced VEGF expression by HIF-1 increases.
摘要翻译：本发明涉及抑制HF-1活性的化合物，其制备方法以及含有该化合物作为活性成分的药物组合物。本发明的化合物通过非选择性细胞毒性表现出抗癌活性，但通过抑制HIF-1的活性，该转录因子在癌细胞生长和转移中起重要作用。因此，根据本发明的化合物或其药学上可接受的盐抑制HIF-1活性，因此可以用作结肠癌，肝癌，胃癌和乳腺癌等实体瘤的治疗剂。此外，根据本发明的化合物或其药学上可接受的盐可以用作用于糖尿病性视网膜病变或关节炎的治疗剂的活性成分，当HIF-1的缺氧诱导的VEGF表达增加时，可能变差。

6. 发明申请

US20130237542A1 ARYLOXY PHENOXY ACRYLIC COMPOUND HAVING HIF-1 INHIBITION ACTIVITY, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS AN ACTIVE INGREDIENT 有权
标题翻译：具有HIF-1抑制活性的芳族羟基丙烯酸酯化合物，其制备方法和含有活性成分的药物组合物
公开(公告)号：US20130237542A1
公开(公告)日：2013-09-12
申请号：US13880642
申请日：2011-10-17
申请人： Kyeong Lee , Mi Sun Won , Hwan Mook Kim , Song Kyu Park , Kiho Lee , Ki Hoon Lee , Chang Woo Lee , Jung Joon Lee , Kyung Sook Chung , Bo Kyung Kim , Yinglan Jin , Seung-hee Lee
发明人： Kyeong Lee , Mi Sun Won , Hwan Mook Kim , Song Kyu Park , Kiho Lee , Ki Hoon Lee , Chang Woo Lee , Jung Joon Lee , Kyung Sook Chung , Bo Kyung Kim , Yinglan Jin , Seung-hee Lee
IPC分类号： C07C235/28 , C07D295/088 , C07C311/16
CPC分类号： A61K31/5375 , A61K9/0019 , A61K9/08 , A61K9/14 , A61K9/20 , A61K9/48 , A61K31/167 , A61K31/196 , A61K31/24 , A61K31/34 , A61K31/40 , A61K31/417 , A61K31/4409 , C07C233/07 , C07C235/28 , C07C311/16 , C07C311/46 , C07C317/40 , C07C2603/74 , C07D295/088
摘要： The present invention relates to a compound inhibiting HF-1 activity, a preparation method of the same, and a pharmaceutical composition comprising the same as an active ingredient. The compound of the present invention demonstrates anticancer activity not by non-selective cytotoxicity but by inhibiting the activity of HIF-1, the transcription factor playing an important role in cancer cell growth and metastasis. Accordingly, the compound or the pharmaceutically acceptable salt thereof according to the present invention inhibits HIF-1 activity, and therefore can be used as a therapeutic agent for solid tumors such as colon cancer, liver cancer, stomach cancer and breast cancer. In addition, the compound or the pharmaceutically acceptable salt thereof according to the present invention can be used as an active ingredient for a therapeutic agent for diabetic retinopathy or arthritis which may become worse when hypoxia-induced VEGF expression by HIF-1 increases.
摘要翻译：本发明涉及抑制HF-1活性的化合物，其制备方法以及含有该化合物作为活性成分的药物组合物。本发明的化合物通过非选择性细胞毒性表现出抗癌活性，但通过抑制HIF-1的活性，该转录因子在癌细胞生长和转移中起重要作用。因此，根据本发明的化合物或其药学上可接受的盐抑制HIF-1活性，因此可以用作结肠癌，肝癌，胃癌和乳腺癌等实体瘤的治疗剂。此外，根据本发明的化合物或其药学上可接受的盐可以用作用于糖尿病性视网膜病变或关节炎的治疗剂的活性成分，当HIF-1的缺氧诱导的VEGF表达增加时，可能变差。

7. 发明申请

US20100249402A1 NOVEL BENZAMIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OSTEPOROSIS COMPRISING THE SAME 审中-公开
标题翻译：新型苯扎明衍生物，其制备方法和用于预防或治疗包含其的药物组合物的药物组合物
公开(公告)号：US20100249402A1
公开(公告)日：2010-09-30
申请号：US12670814
申请日：2008-07-28
申请人： Jei Man Ryu , Jin Soo Lee , Young Goo Jin , Jae Hoon Park , Bo Kyung Kim , Dae Yeon Won , Yun-Ha Hwang , Ki Yoon Kim , Sae Kwang Ku
发明人： Jei Man Ryu , Jin Soo Lee , Young Goo Jin , Jae Hoon Park , Bo Kyung Kim , Dae Yeon Won , Yun-Ha Hwang , Ki Yoon Kim , Sae Kwang Ku
IPC分类号： C07D417/02 , C07D413/02
CPC分类号： C07D277/22 , C07D277/28 , C07D277/40 , C07D417/06
摘要： The present invention relates to novel benzamidine derivatives, a process for the preparation thereof and a pharmaceutical composition for preventing or treating osteoporosis comprising the same. The benzamidine derivatives of the present invention effectively inhibit osteoclast differentiation at an extremely low concentration, and thus can be advantageously used for the prevention and treatment of osteoporosis.
摘要翻译：本发明涉及新的苄脒衍生物，其制备方法和用于预防或治疗包含其的骨质疏松症的药物组合物。本发明的苄脒衍生物以极低的浓度有效抑制破骨细胞分化，因此可有利地用于预防和治疗骨质疏松症。

8. 发明授权

US07149181B2 Apparatus and method for re-transmitting erroneous packet data 有权
标题翻译：用于重传错误分组数据的装置和方法
公开(公告)号：US07149181B2
公开(公告)日：2006-12-12
申请号：US09801682
申请日：2001-03-09
申请人： Bo Kyung Kim
发明人： Bo Kyung Kim
IPC分类号： H04L12/56
CPC分类号： H04L1/188
摘要： An apparatus and method for re-transmitting erroneous packet data is disclosed. Each of the physical layers of the system includes a buffer, a timer, a controller, and a radio frequency unit. The buffer temporarily stores transmitted data in the form of a final data frame capable of being transmitted on a transmission line without any processing. The timer is a time counter adapted to limit the time, for which the transmission end waits for an acknowledgment to a transmission of data after the data transmission is made. If no acknowledgment signal is received when the timer expires the buffered data in the physical layer is re-transmitted. This reduces the data transmission delay resulting from the inter-layer movement of data generated during a re-transmission of erroneous data, and the transmission delay of packet data resulting from overhead time.
摘要翻译：公开了重传错误分组数据的装置和方法。系统的每个物理层包括缓冲器，定时器，控制器和射频单元。缓冲器临时存储能够在传输线上传输的最终数据帧形式的发送数据，而不进行任何处理。定时器是一种时间计数器，适用于限制传输结束在进行数据传输之后等待数据传输确认的时间。如果在定时器到期时没有接收到确认信号，物理层中缓存的数据被重新发送。这减少了在错误数据的重新传输期间产生的数据的层间移动以及由开销时间产生的分组数据的传输延迟所导致的数据传输延迟。

9. 发明授权

US08039635B2 N-hydroxy-4-{5-[4-(5-isopropyl-2-methyl-1,3-thiazol-4-yl) phenoxy]pentoxy} benzamidine 2 ethansulfonic acid salt, process for the preparation thereof and pharmaceutical composition comprising the same 失效
标题翻译： N-羟基-4- {5- [4-（5-异丙基-2-甲基-1,3-噻唑-4-基）苯氧基]戊氧基}苄脒2乙磺酸盐，其制备方法和药物组合物，其包含一样
公开(公告)号：US08039635B2
公开(公告)日：2011-10-18
申请号：US12531807
申请日：2008-04-21
申请人： Jin Soo Lee , Soon Ki Cho , Seoung Kyoo Sung , Young Goo Jin , Jae Hoon Park , Bo Kyung Kim , Ja Hyun Cha , Eun Hee Cho , Jei Man Ryu
发明人： Jin Soo Lee , Soon Ki Cho , Seoung Kyoo Sung , Young Goo Jin , Jae Hoon Park , Bo Kyung Kim , Ja Hyun Cha , Eun Hee Cho , Jei Man Ryu
IPC分类号： A61K31/426 , C07D277/30
CPC分类号： C07D277/24
摘要： N-hydroxy-4-{5-[4-(5-isopropyl-2-methyl-1,3-thiazol-4-yl)phenoxy]pentoxy} benzamidine 2 ethansulfonic acid salt, a process for the preparation thereof, a pharmaceutical composition for preventing and treating osteoporosis, bone fractures or allergic inflammatory diseases, comprising the same, and an oral formulation for preventing and treating osteoporosis, bone fractures or allergic inflammatory diseases, comprising the same are described.
摘要翻译： N-羟基-4- {5- [4-（5-异丙基-2-甲基-1,3-噻唑-4-基）苯氧基]戊氧基}苄脒2乙磺酸盐，其制备方法，药物描述了用于预防和治疗骨质疏松症，骨折或过敏性炎性疾病的组合物，以及用于预防和治疗含有该组合物的骨质疏松症，骨折或过敏性炎性疾病的口服制剂。

10. 发明申请

US20050275755A1 Image processing device, method, and medium 审中-公开
标题翻译：图像处理装置，方法和介质
公开(公告)号：US20050275755A1
公开(公告)日：2005-12-15
申请号：US11151372
申请日：2005-06-14
申请人： Bo-kyung Kim
发明人： Bo-kyung Kim
IPC分类号： H04N5/21 , H04N5/445
CPC分类号： H04N5/44504 , H04N21/431 , H04N21/4348 , H04N21/4858 , H04N21/488
摘要： An image processing device, method, and medium providing an optimal video signal to users when a video signal is output after predetermined data is overlaid over the video signal. The image processing device includes a separating unit that separates a video signal, an audio signal, and additional information from a broadcast signal, a memory unit that stores a partial video signal corresponding to a predetermined area of an original video signal, the partial video signal obtained by decoding the separated video signal, and a control unit that overlays the separated additional information over the stored partial video signal and outputs a final video signal obtained by overlaying the partial video signal over which the separated additional information is overlaid over the original video signal.
摘要翻译：当在视频信号上叠加预定数据之后，当输出视频信号时，向用户提供最佳视频信号的图像处理装置，方法和介质。图像处理装置包括：分离单元，从广播信号分离视频信号，音频信号和附加信息;存储单元，存储对应于原始视频信号的预定区域的部分视频信号;部分视频信号通过对分离的视频信号进行解码获得的控制单元，以及覆盖存储的部分视频信号上的分离的附加信息的控制单元，并输出通过将分离的附加信息覆盖在原始视频信号上的部分视频信号重叠而获得的最终视频信号。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式