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1. 发明授权

US09089108B2 Adhesion system for rawhide and meat chew for dogs 有权
标题翻译：狗的生皮和肉咀嚼粘合系统
公开(公告)号：US09089108B2
公开(公告)日：2015-07-28
申请号：US12215082
申请日：2008-06-25
申请人： David A. Anderson , Richard L. Harpe
发明人： David A. Anderson , Richard L. Harpe
IPC分类号： A23B4/00 , A01K11/00
CPC分类号： A01K15/026
摘要： A palatable and long lasting chew for dogs combines a rawhide fraction with meat, poultry or fish. The rawhide fraction is from rawhide splits die cut into desired shapes. The rawhide fraction is then dehydrated to approximately 6% moisture. The meat, poultry or fish fraction then attaches to the rawhide component. The meat fraction is held to the rawhide fraction utilizing a food grade adhesive from milk protein hydrolysate. The milk protein hydrolysate is solubilized in hot water to a solids level between 3% and 30%. The solution is then applied to the rawhide component where the meat fraction will contact the rawhide. The meat fraction is then deposited onto the coated rawhide surface and the chew is then dehydrated to laminate the meat fraction to the rawhide fraction. Alternatively, the food grade adhesive is blended with the meat fraction and deposited in the rawhide.
摘要翻译：狗的可口和持久的咀嚼将生皮部分与肉，家禽或鱼相结合。生皮分数是从生皮分割成切割成所需的形状。然后将生皮部分脱水至约6％的水分。肉类，禽类或鱼类馏分然后附着在生皮成分上。使用来自乳蛋白水解产物的食品级粘合剂将肉类部分保持在生皮部分。将乳蛋白水解物溶于热水至3％至30％之间的固体含量。然后将该溶液施加到生皮部分，其中肉分数将接触生皮。然后将肉类部分沉积到涂覆的生皮表面上，然后将咀嚼物脱水以将肉类部分层压至生皮部分。或者，食品级粘合剂与肉类部分混合并沉积在生皮中。

2. 发明授权

US08706202B2 Implantable medical device with adaptive signal processing and artifact cancellation 有权
标题翻译：具有自适应信号处理和伪像消除的植入式医疗器械
公开(公告)号：US08706202B2
公开(公告)日：2014-04-22
申请号：US12687946
申请日：2010-01-15
申请人： Richard J. O'Brien , D. Curtis Deno , David A. Anderson , David R. Bloem
发明人： Richard J. O'Brien , D. Curtis Deno , David A. Anderson , David R. Bloem
IPC分类号： A61B5/04
CPC分类号： A61B5/0205 , A61B5/1455 , A61B5/7207 , A61N1/3718 , A61N1/3925 , G06K9/00503 , G06K9/6247 , G06K2009/00939
摘要： A medical device having a sensor sensing an n-dimensional signal during a first known variable condition and during a second known variable condition different from the first known variable condition, a processor performing principal component analysis (PCA) on the sensed n-dimensional signal to generate a first template corresponding to a principal component of variation associated with the first known variable condition and a second template corresponding to a principal component of variation associated with the second known variable condition, a storage device storing the first template and the second template, and a controller detecting a patient condition in response to the stored templates.
摘要翻译：一种医疗装置，其具有在第一已知可变条件期间和在与第一已知可变条件不同的第二已知可变条件期间感测n维信号的传感器，处理器对所感测的n维信号执行主分量分析（PCA）生成对应于与第一已知可变条件相关联的变化的主成分的第一模板和对应于与第二已知可变条件相关联的变化的主成分的第二模板，存储第一模板和第二模板的存储装置，以及响应于所存储的模板检测患者状况的控制器。

3. 发明授权

US08515537B2 Tissue oxygenation monitoring in heart failure 有权
标题翻译：心力衰竭组织氧合监测
公开(公告)号：US08515537B2
公开(公告)日：2013-08-20
申请号：US12797823
申请日：2010-06-10
申请人： Can Cinbis , James K. Carney , Jonathan L. Kuhn , David A. Anderson
发明人： Can Cinbis , James K. Carney , Jonathan L. Kuhn , David A. Anderson
IPC分类号： A61N1/00
CPC分类号： A61N1/36557
摘要： A medical device system and associated method control the delivery of a therapy to a patient. The system includes an activity sensor and detects a change in activity level of the patient. The system further include an optical sensor to sense signal corresponding to tissue light attenuation. The system computes a tissue oxygenation measurement in response to detecting a change in activity level. A parameter controlling delivery of the therapy is adjusted in response to detecting the decreased tissue oxygenation.
摘要翻译：医疗装置系统和相关联的方法控制对患者的治疗的递送。该系统包括活动传感器并检测患者的活动水平的变化。该系统还包括用于感测对应于组织光衰减的信号的光学传感器。响应于检测到活动水平的变化，系统计算组织氧合测量。响应于检测到组织氧合减少而调整治疗递送的参数。

4. 发明授权

US08463346B2 Absolute calibrated tissue oxygen saturation and total hemoglobin volume fraction 有权
$Absolute calibrated tissue oxygen saturation and total hemoglobin volume fraction$
标题翻译：绝对校准组织氧饱和度和总血红蛋白体积分数
公开(公告)号：US08463346B2
公开(公告)日：2013-06-11
申请号：US12797800
申请日：2010-06-10
申请人： Jonathan L. Kuhn , David A. Anderson , Can Cinbis , Richard J. O'Brien , Yong K. Cho , Thomas J. Mullen , Avram Scheiner , Rodolphe P. Katra
发明人： Jonathan L. Kuhn , David A. Anderson , Can Cinbis , Richard J. O'Brien , Yong K. Cho , Thomas J. Mullen , Avram Scheiner , Rodolphe P. Katra
IPC分类号： A61B5/00
CPC分类号： A61N1/36557 , A61B5/1459 , A61N1/37258
摘要： A medical device for monitoring a patient condition includes a sensor capable of being advanced transvascularly to be positioned along a volume of tissue, the sensor including a first combination of a light source and a light detector to emit light into a volume of tissue and to detect light scattered by the volume of tissue and to generate a first output signal corresponding to an intensity of the detected light. A control module is coupled to the light source to control the light source to emit light at least four spaced-apart light wavelengths, and a monitoring module is coupled to the light detector to receive the output signal and compute a measure of tissue oxygenation using the light detector output signal.
摘要翻译：用于监测患者状况的医疗装置包括能够经血管内先进地沿着组织体积定位的传感器，所述传感器包括光源和光检测器的第一组合，以将光发射到一定体积的组织中并且检测通过组织体积散射的光并产生对应于检测到的光的强度的第一输出信号。控制模块耦合到光源以控制光源发射至少四个间隔开的光波长的光，并且监测模块耦合到光检测器以接收输出信号并且使用光检测器输出信号。

5. 发明授权

US08346332B2 Absolute calibrated tissue oxygen saturation and total hemoglobin volume fraction 有权
$Absolute calibrated tissue oxygen saturation and total hemoglobin volume fraction$
标题翻译：绝对校准组织氧饱和度和总血红蛋白体积分数
公开(公告)号：US08346332B2
公开(公告)日：2013-01-01
申请号：US12797811
申请日：2010-06-10
申请人： Jonathan L. Kuhn , David A. Anderson , Can Cinbis , Richard J. O'Brien , Yong K. Cho , Thomas J. Mullen , Avram Scheiner , Rodolphe P. Katra
发明人： Jonathan L. Kuhn , David A. Anderson , Can Cinbis , Richard J. O'Brien , Yong K. Cho , Thomas J. Mullen , Avram Scheiner , Rodolphe P. Katra
IPC分类号： A61B5/00
CPC分类号： A61N1/36557 , A61B5/1459 , A61N1/37258
摘要： A medical device for monitoring a patient condition includes a first combination of a light source and a light detector to emit light into a volume of tissue, detect light scattered by the volume of tissue, and provide a first output signal corresponding to an intensity of the detected light. A control module is coupled to the light source to control the light source to emit light at least four spaced-apart light wavelengths, and a monitoring module is coupled to the light detector to receive the output signal, compute a measure of tissue oxygenation in response to the light detector output signal, and detect tissue hypoxia using the measure of tissue oxygenation.
摘要翻译：用于监测患者状况的医疗装置包括光源和光检测器的第一组合，以将光发射到组织的体积中，检测由组织体积散射的光，并提供对应于组织的强度的第一输出信号检测到光。控制模块耦合到光源以控制光源发射至少四个间隔开的光波长的光，并且监测模块耦合到光检测器以接收输出信号，计算响应中组织氧合的量度到光检测器输出信号，并使用组织氧合的测量来检测组织缺氧。

6. 发明申请

US20120296228A1 HEART SOUNDS-BASED PACING OPTIMIZATION 有权
标题翻译：基于心脏声音的PAC优化
公开(公告)号：US20120296228A1
公开(公告)日：2012-11-22
申请号：US13111260
申请日：2011-05-19
申请人： Xusheng Zhang , Aleksandre T. Sambelashvili , David A. Anderson , Zhendong Song
发明人： Xusheng Zhang , Aleksandre T. Sambelashvili , David A. Anderson , Zhendong Song
IPC分类号： A61N1/365 , A61B5/0205
CPC分类号： A61N1/36578 , A61B5/0006 , A61B5/04017 , A61B5/0452 , A61B5/4848 , A61N1/36585 , A61N1/3682 , A61N1/3684
摘要： An implantable medical device receives both heart sound and electrogram signals. A processor within the implantable medical device extracts physiologically relevant information from both the heart sound signal and the electrogram signal. Based on the extracted physiologically relevant information a set of pacing parameters is evaluated. In certain examples, the values of the pacing parameters may be changed by the implantable medical device in response to the physiologically relevant information extracted from the heart sound signal and the electrogram signal.
摘要翻译：可植入医疗设备接收心音和电描记信号。可植入医疗装置内的处理器从心音信号和电描记图信号中提取生理相关信息。基于提取的生理相关信息，评估一组起搏参数。在某些示例中，响应于从心脏声音信号和电描记图信号提取的生理学相关信息，可由可植入医疗装置改变起搏参数的值。

7. 发明授权

US08217836B1 Tactical relative navigation using orientation transfer and ranging 有权
标题翻译：使用方向转移和测距的战术相对导航
公开(公告)号：US08217836B1
公开(公告)日：2012-07-10
申请号：US12713659
申请日：2010-02-26
申请人： David A. Anderson , Patrick Y. Hwang , Joseph M. Kelly
发明人： David A. Anderson , Patrick Y. Hwang , Joseph M. Kelly
IPC分类号： G01S5/02 , G01S3/02
CPC分类号： G01S5/0284 , G01S13/74 , G01S13/86 , G01S13/874
摘要： A navigation system/solution, suitable for use in a GPS-denied environment, may be implemented via a node, the node being mounted on-board a vehicle, such as a tactical aircraft. The system/solution allows for a single component of the node to obtain/determine a bearing measurement (via an orientation transfer scheme) and a range measurement (via a round trip timing scheme) based upon signals transmitted between the node and a second node, and further allows for the bearing and range measurements to be received and processed by a navigation processor of the node for determining a location of the node.
摘要翻译：适用于GPS拒绝环境的导航系统/解决方案可以经由节点来实现，该节点被安装在诸如战术飞机的车辆上。系统/解决方案允许节点的单个组件基于在节点和第二节点之间传输的信号来获得/确定承载测量（通过定向传递方案）和范围测量（经由往返定时方案）并且还允许用于确定节点的位置的节点的导航处理器接收和处理轴承和距离测量。

8. 发明申请

US20120130208A1 COEFFICENT DETERMINATION FOR BLOOD OXYGEN SATURATION AND TOTAL HEMOGLOBIN CONCENTRATION INDICES 有权
标题翻译：血氧饱和度和总HEMOGLOBIN浓度指标的系数确定
公开(公告)号：US20120130208A1
公开(公告)日：2012-05-24
申请号：US12948884
申请日：2010-11-18
申请人： Jonathan L. Kuhn , Can Cinbis , David A. Anderson , James K. Carney
发明人： Jonathan L. Kuhn , Can Cinbis , David A. Anderson , James K. Carney
IPC分类号： A61B5/1459
CPC分类号： A61B5/1459 , A61B5/0075 , A61B5/14535 , A61B5/14542 , A61B5/14551 , A61B5/1495 , A61B5/4836
摘要： A first concentration of a chromophore corresponding to a measurement volume of an optical sensor is determined. A second concentration of the chromophore is obtained in the vicinity of the measurement volume corresponding to a change in at least one of a total concentration of the chromophore and a relative concentration of a first form of the chromophore to the total concentration of the chromophore in the measurement volume. Light remittance measurements including a first light wavelength and a second light wavelength are obtained corresponding to the first chromophore concentration and the second chromophore concentration. A coefficient for computing an index of a change in the chromophore concentration is computed using the difference between the first and second chromophore concentrations and the first and second light remittance measurements.
摘要翻译：确定对应于光学传感器的测量体积的发色团的第一浓度。在测量体积附近获得发色团的第二浓度，其对应于发色团的总浓度和发色团的第一形式的相对浓度与发色团的总浓度中的至少一个的变化相关测量体积。对应于第一发色团浓度和第二发色团浓度获得包括第一光波长和第二光波长的光汇率测量。使用第一和第二生色团浓度与第一和第二光汇率测量之间的差来计算计算发色团浓度变化指数的系数。

9. 发明授权

US08140156B2 Heart sound sensing to reduce inappropriate tachyarrhythmia therapy 有权
标题翻译：心音检测减少不适当的快速性心律失常治疗
公开(公告)号：US08140156B2
公开(公告)日：2012-03-20
申请号：US12495204
申请日：2009-06-30
申请人： Xusheng Zhang , David A. Anderson , Jeffrey M. Huston , Jeffrey M. Gillberg
发明人： Xusheng Zhang , David A. Anderson , Jeffrey M. Huston , Jeffrey M. Gillberg
IPC分类号： A61N1/00
CPC分类号： A61N1/3621 , A61N1/3624 , A61N1/36528 , A61N1/36535
摘要： Techniques for detecting heart sounds to reduce inappropriate tachyarrhythmia therapy are described. In some examples, a medical device determines that a cardiac rhythm of the patient is treatable with a therapy, such as a defibrillation pulse, based on a cardiac electrogram (EGM). The medical device analyzes detected heart sounds, and withholds or allows the therapy based on the analysis of the heart sounds.
摘要翻译：描述了用于检测心音以减少不适当的快速性心律失常治疗的技术。在一些示例中，医疗装置通过基于心电图（EGM）的治疗，例如除颤脉冲来确定患者的心律是可治疗的。医疗器械分析检测到的心脏声音，并根据对心脏声音的分析，保留或允许进行治疗。

10. 发明授权

US08127857B2 Single trip, tension set, metal-to-metal sealing, internal lockdown tubing hanger 有权
标题翻译：单行程，张力设定，金属对金属密封，内部锁定管衣架
公开(公告)号：US08127857B2
公开(公告)日：2012-03-06
申请号：US12502153
申请日：2009-07-13
申请人： James A. Sinnott , Arlane P. Christie , David A. Anderson
发明人： James A. Sinnott , Arlane P. Christie , David A. Anderson
IPC分类号： E21B23/00 , E21B23/01
CPC分类号： E21B33/04 , E21B23/02 , E21B33/0422
摘要： A system, apparatus, and method to apply tension to completion tubing in a wellbore. The system, apparatus, and method comprises an inner and outer tubing hanger, with the string of tubing attached to the inner tubing hanger. A running tool lands the outer tubing hanger on a landing shoulder and continues to lower the inner tubing hanger into the wellbore until the lower end of the inner tubing hanger latches into a retaining device. The running tool then sets a seal which holds the outer tubing hanger in position and causes a ratcheting mechanism to move to an engaged position. The running tool then withdraws the inner tubing hanger a predetermined distance until the inner tubing hanger engages the ratcheting mechanism.
摘要翻译：对井筒内的完井管施加张力的系统，装置和方法。该系统，装置和方法包括内管和外管悬挂架，其中一连串管连接到内管悬挂架上。运行工具将外管挂钩挂在着陆台肩上，继续将内管衣架降低到井筒中，直到内管悬挂架的下端闩锁到保持装置中。然后，运行工具设置一个密封件，该密封件将外管衣架保持在适当位置，并使棘轮机构移动到接合位置。然后，运行工具将内管悬挂器取出预定距离，直到内管悬挂器接合棘轮机构。

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