专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US09222819B2 Tracking and controlling fluid delivery from chamber 有权
标题翻译：跟踪和控制从腔室输送液体
公开(公告)号：US09222819B2
公开(公告)日：2015-12-29
申请号：US13487000
申请日：2012-06-01
申请人： Christian A. Gutierrez , Ellis Meng
发明人： Christian A. Gutierrez , Ellis Meng
IPC分类号： G01F3/22 , B67D1/04 , B67D1/08 , G01F3/20 , G01F11/08 , G01M3/16 , G01M3/40
CPC分类号： G01F3/227 , B67D1/0437 , B67D1/0855 , G01F3/20 , G01F11/086 , G01M3/16 , G01M3/40
摘要： Electrochemical impedance may be used for accurate and real-time tracking and control of fluid delivery from fluid-filled chambers, such as from drug delivery devices. At least two measurement electrodes may be placed within the chamber in contact with the fluid to be sensed. Application of a small alternating current using these electrodes through the fluid/drug may allow measurement of electrochemical impedance. Volumetric changes of the compressible chamber due to movement of at least one surface within the compressible chamber (such as an actuating bellows or flexible diaphragm), may induce changes in the measured electrochemical impedance. Measuring these changes may allow for tracking of ejected liquid volumes from the compressible chamber. By taking the time-derivative of this signal, the rate of volume change can be tracked and therefore the rate of ejected fluid (flow rate) can be deduced.
摘要翻译：电化学阻抗可用于精确和实时跟踪和控制从填充液体的腔室（例如来自药物输送装置）的流体输送。至少两个测量电极可以放置在室内与要感测的流体接触。使用这些电极通过流体/药物施加小的交流电流可以测量电化学阻抗。由于可压缩室内的至少一个表面的移动（例如致动波纹管或柔性隔膜），可压缩室的体积变化可能引起测量的电化学阻抗的变化。测量这些变化可以允许跟踪来自可压缩室的喷射液体体积。通过采用该信号的时间导数，可以跟踪体积变化率，因此可以推导出喷射流体的速率（流量）。

2. 发明授权

US08490497B2 Microelectromechanical (MEMS) pressure transducer 有权
标题翻译：微机电（MEMS）压力传感器
公开(公告)号：US08490497B2
公开(公告)日：2013-07-23
申请号：US13052958
申请日：2011-03-21
申请人： Christian A. Gutierrez , Ellis Meng
发明人： Christian A. Gutierrez , Ellis Meng
IPC分类号： G01L9/00 , H01S4/00
CPC分类号： G01L11/00 , G01L11/02 , G01L11/04 , Y10T29/49002
摘要： A pressure transducer for measuring pressure may include an all-polymer chamber that has no dimension greater than 1 mm. There may be fluid within the chamber, a gaseous bubble trapped within the fluid, and electrodes in contact with the fluid. The electrodes may enable a measurement of changes in the impedance of the fluid caused by changes in the volume of the gaseous bubble caused by changes in the pressure to be measured.The pressure transducer may be made by depositing the chamber, placing the fluid within the chamber, and generating the gaseous bubble within the fluid with electrolysis.
摘要翻译：用于测量压力的压力传感器可以包括没有尺寸大于1mm的全聚合物室。室内可能存在流体，被捕获在流体内的气泡和与流体接触的电极。电极可以测量由待测量的压力变化引起的气泡体积变化引起的流体阻抗的变化。压力传感器可以通过沉积室，将流体放置在室内，并通过电解产生流体内的气泡来制造。

3. 发明申请

US20120017423A1 INTERCONNECT FOR MEMS DEVICE INCLUDING A VISCOELASTIC SEPTUM 失效
标题翻译：用于包括粘弹性体的MEMS器件的互连
公开(公告)号：US20120017423A1
公开(公告)日：2012-01-26
申请号：US13251959
申请日：2011-10-03
申请人： Ellis Meng , Ronalee Lo
发明人： Ellis Meng , Ronalee Lo
IPC分类号： H01S4/00
CPC分类号： B01L3/502715 , B01L2200/027 , B01L2300/044 , B01L2300/0816 , B01L2300/0858 , B01L2300/0887 , B01L2400/046 , G01N35/1079
摘要： Provided is a micro electro mechanical systems (MEMS) device for use with an elongate structure. The MEMS device includes a generally planar substrate, a device wall layer formed upon the substrate, a septum cavity formed in the device wall layer, a channel formed in the device wall layer in fluid communication with the septum cavity, and a septum element disposed in the septum cavity. The septum element is formed of a viscoelastic material. The septum element defines a septum entry surface and a septum exit surface with the septum exit surface being exposed to the channel and disposed between the septum entry surface and the channel. The septum element is without any openings formed through the septum element extending between the septum entry and exit surfaces. Methods of manufacturing and interacting with the MEMS device are also provided.
摘要翻译：提供了一种用于细长结构的微机电系统（MEMS）装置。 MEMS器件包括大致平面的衬底，形成在衬底上的器件壁层，形成在器件壁层中的隔膜腔，形成在与隔膜腔流体连通的器件壁层中的通道和设置在隔膜腔中的隔膜元件隔膜腔。隔膜元件由粘弹性材料形成。隔膜元件限定隔膜入口表面和隔膜出口表面，其中隔膜出口表面暴露于通道并且设置在隔膜入口表面和通道之间。隔膜元件没有通过在隔膜入口和出口表面之间延伸的隔膜元件形成的任何开口。还提供了与MEMS器件的制造和相互作用的方法。

4. 发明授权

US08087310B2 Interconnect for MEMS device including a viscoelastic septum 有权
标题翻译：用于MEMS器件的互连，包括粘弹性隔膜
公开(公告)号：US08087310B2
公开(公告)日：2012-01-03
申请号：US12357330
申请日：2009-01-21
申请人： Ellis Meng , Ronalee Lo
发明人： Ellis Meng , Ronalee Lo
IPC分类号： G01N1/00
CPC分类号： B01L3/502715 , B01L2200/027 , B01L2300/044 , B01L2300/0816 , B01L2300/0858 , B01L2300/0887 , B01L2400/046 , G01N35/1079
摘要： Provided is a micro electro mechanical systems (MEMS) device for use with an elongate structure. The MEMS device includes a generally planar substrate, a device wall layer formed upon the substrate, a septum cavity formed in the device wall layer, a channel formed in the device wall layer in fluid communication with the septum cavity, and a septum element disposed in the septum cavity. The septum element is formed of a viscoelastic material. The septum element defines a septum entry surface and a septum exit surface with the septum exit surface being exposed to the channel and disposed between the septum entry surface and the channel. The septum element is without any openings formed through the septum element extending between the septum entry and exit surfaces. Methods of manufacturing and interacting with the MEMS device are also provided.
摘要翻译：提供了一种用于细长结构的微机电系统（MEMS）装置。 MEMS器件包括大致平面的衬底，形成在衬底上的器件壁层，形成在器件壁层中的隔膜腔，形成在与隔膜腔流体连通的器件壁层中的通道和设置在隔膜腔中的隔膜元件隔膜腔。隔膜元件由粘弹性材料形成。隔膜元件限定隔膜入口表面和隔膜出口表面，隔膜出口表面暴露于通道并且设置在隔膜入口表面和通道之间。隔膜元件没有通过在隔膜入口和出口表面之间延伸的隔膜元件形成的任何开口。还提供了与MEMS器件的制造和相互作用的方法。

5. 发明授权

US07252006B2 Implantable mechanical pressure sensor and method of manufacturing the same 有权
标题翻译：可植入式机械压力传感器及其制造方法
公开(公告)号：US07252006B2
公开(公告)日：2007-08-07
申请号：US11148124
申请日：2005-06-07
申请人： Yu-Chong Tai , Ellis Meng , Po-Jui Chen , Damien C. Rodger , Mark Humayun
发明人： Yu-Chong Tai , Ellis Meng , Po-Jui Chen , Damien C. Rodger , Mark Humayun
IPC分类号： G01L9/00
CPC分类号： A61B3/16 , A61B2562/02 , A61B2562/028 , G01L7/045
摘要： A biocompatible, mechanical, micromachined pressure sensor and methods of manufacturing such a pressure sensor are provided. The pressure sensor of the current invention includes a high-aspect-ratio curved-tube structure fabricated through a one-layer parylene process. The pressure sensor of the current invention requires zero power consumption and indicates the pressure variation by changes of the in situ in-plane motion of the sensor, which can be gauged externally by a direct and convenient optical observation. In one embodiment, the pressure sensor of the current invention has been shown to work as an IOP sensor for eye implantation where the intraocular in-plane motion of the sensor can be recorded from outside of the eye, such that the intraocular pressure in glaucoma patients can be constantly monitored.
摘要翻译：提供生物相容的，机械的，微加工的压力传感器以及制造这种压力传感器的方法。本发明的压力传感器包括通过一层聚对二甲苯工艺制造的高纵横比弯曲管结构。本发明的压力传感器需要零功率消耗，并且通过传感器的原位面内运动的变化来指示压力变化，其可以通过直接和方便的光学观察在外部测量。在一个实施例中，本发明的压力传感器已经被证明可用作眼睛植入的IOP传感器，其中可以从眼睛外部记录传感器的眼内平面内运动，使得青光眼患者的眼内压可以不断监控。

6. 发明申请

US20060247664A1 Micromachined tissue anchors for securing implants without sutures 审中-公开
标题翻译：微加工组织锚，用于固定植入物，无缝线
公开(公告)号：US20060247664A1
公开(公告)日：2006-11-02
申请号：US11371219
申请日：2006-03-07
申请人： Ellis Meng , Yu-Chong Tai , Damien Rodger , Po-Jui Chen , Mark Humayun
发明人： Ellis Meng , Yu-Chong Tai , Damien Rodger , Po-Jui Chen , Mark Humayun
IPC分类号： A61F2/02 , A61B3/16
CPC分类号： A61B3/16 , A61B5/6821 , A61B5/6882
摘要： Systems and methods for attaching an implant device to tissue by mechanically (and non-invasively) anchoring the device to the tissue. The systems and methods provide a safe, practical way to attach an implant device to tissue in a non-invasive, or less invasive manner. According to the present invention, an implant device includes one or more protruding anchor-like structures for securely attaching to tissue. One or more device features, such as sensing elements, may be incorporated on the implant device. The anchor structures are configured and arranged to match the topology and features of the tissue environment where implant is to occur.
摘要翻译：通过机械地（而非侵入式）将装置固定在组织上来将植入装置附着到组织的系统和方法。该系统和方法提供了以非侵入性或较小侵入性方式将植入装置附接到组织的安全且实用的方式。根据本发明，植入装置包括用于牢固地附接到组织的一个或多个突出的锚固结构。可以在植入装置上并入一个或多个装置特征，例如感测元件。锚结构被配置和布置成匹配将要进行植入的组织环境的拓扑和特征。

7. 发明授权

US08372046B2 Drug delivery device with in-plane bandpass regulation check valve in heat-shrink packaging 有权
标题翻译：药物输送装置，带有热收缩包装内的带内调节止回阀
公开(公告)号：US08372046B2
公开(公告)日：2013-02-12
申请号：US12709188
申请日：2010-02-19
申请人： Ellis Meng , Ronalee Lo Mann
发明人： Ellis Meng , Ronalee Lo Mann
IPC分类号： A61M5/00
CPC分类号： A61M5/00 , A61F9/0017 , A61M5/14276 , A61M5/16881 , A61M2039/2413 , A61M2039/242 , A61M2210/0612
摘要： A drug delivery device may include a drug reservoir configured to contain and controllably deliver a fluidic drug. A tube may be configured to deliver the fluid from the drug reservoir through a lumen in the tube to another location. A valve wholly within the lumen of the tube may regulate the flow of the fluid through the tube without substantially diverting the direction in which the fluid flows through the tube. The valve may contain only a single member which moves during operation of the valve. The valve may be configured to regulate the flow of fluid in a bandpass manner by allowing fluid to flow through the valve only when the pressure of the fluid is above a minimum and below a maximum. The valve may be held in place within the tube solely by frictional force between the valve and a wall of the tube.
摘要翻译：药物递送装置可以包括被配置为容纳和可控地递送流体药物的药物储存器。管可以被配置成将来自药物储存器的流体通过管中的管腔输送到另一位置。完全在管腔中的阀可以调节流体通过管的流动，而不会使流体流过管的方向基本上转向。阀可以仅包含在阀操作期间移动的单个构件。阀可以被配置为通过仅当流体的压力高于最小值并且低于最大值时允许流体流过阀门才能以带通方式调节流体的流动。阀可以仅通过阀和管壁之间的摩擦力保持在管内的适当位置。

8. 发明申请

US20110144617A1 MEMS DEVICE AND METHOD FOR DELIVERY OF THERAPEUTIC AGENTS 审中-公开
标题翻译：用于输送治疗剂的MEMS装置和方法
公开(公告)号：US20110144617A1
公开(公告)日：2011-06-16
申请号：US13026136
申请日：2011-02-11
申请人： Ellis MENG , Yu-Chong Tai , Mark S. Humayun , Rajat Agrawal , Ronalee Lo Monterey Park , Jason Shih , Kenrick Kuwahara , Po-Ying Li , Damien Rodger , Po-Jui Chen
发明人： Ellis MENG , Yu-Chong Tai , Mark S. Humayun , Rajat Agrawal , Ronalee Lo Monterey Park , Jason Shih , Kenrick Kuwahara , Po-Ying Li , Damien Rodger , Po-Jui Chen
IPC分类号： A61M5/152 , A61M5/14
CPC分类号： A61F9/0017 , A61K9/0024 , A61K9/0097 , A61M5/14276 , A61M5/14593 , A61M5/155 , A61M5/16877 , A61M5/16881 , A61M37/00 , A61M2005/14204 , A61M2205/0244 , A61M2205/3507 , A61M2207/00 , A61M2210/0612 , B81B2201/058 , B81C1/00119 , B81C2201/019 , F04B43/043 , F16K99/0001 , F16K99/0005 , F16K99/0034 , F16K99/0057 , F16K2099/008 , F16K2099/0088 , Y10T29/49236
摘要： Embodiments of an implantable device for delivering a therapeutic agent to a patient include a reservoir configured to contain a liquid comprising the therapeutic agent, a cannula in fluid communication with the reservoir, and means for forcing fluid from the reservoir into the cannula. Circuitry for controlling the means for forcing fluid from the reservoir into the cannula may be included.
摘要翻译：用于将治疗剂递送到患者的可植入装置的实施例包括：储存器，其构造成容纳包含治疗剂的液体，与储存器流体连通的套管，以及用于迫使流体从储存器进入套管的装置。可以包括用于控制用于将流体从储存器迫使进入套管的装置的电路。

9. 发明申请

US20100305550A1 MEMS DEVICE AND METHOD FOR DELIVERY OF THERAPEUTIC AGENTS 有权
标题翻译：用于输送治疗剂的MEMS装置和方法
公开(公告)号：US20100305550A1
公开(公告)日：2010-12-02
申请号：US12790240
申请日：2010-05-28
申请人： Ellis Meng , Yu-Chong Tai , Mark S. Humayun , Rajat Agrawal , Ronalee Lo , Jason Shih , Kenrick Kuwahara , Po-Ying Li , Damien Rodger , Po-Jui Chen
发明人： Ellis Meng , Yu-Chong Tai , Mark S. Humayun , Rajat Agrawal , Ronalee Lo , Jason Shih , Kenrick Kuwahara , Po-Ying Li , Damien Rodger , Po-Jui Chen
IPC分类号： A61M35/00
CPC分类号： A61F9/0017 , A61K9/0024 , A61K9/0097 , A61M5/14276 , A61M5/14593 , A61M5/155 , A61M5/16877 , A61M5/16881 , A61M37/00 , A61M2005/14204 , A61M2205/0244 , A61M2205/3507 , A61M2207/00 , A61M2210/0612 , B81B2201/058 , B81C1/00119 , B81C2201/019 , F04B43/043 , F16K99/0001 , F16K99/0005 , F16K99/0034 , F16K99/0057 , F16K2099/008 , F16K2099/0088 , Y10T29/49236
摘要： Embodiments of an implantable device for delivering a therapeutic agent to a patient include a reservoir configured to contain a liquid comprising the therapeutic agent, and a cannula in fluid communication with the reservoir. The cannula is shaped to facilitate insertion thereof into a patient's eyeball.
摘要翻译：用于将治疗剂递送到患者的可植入装置的实施例包括构造成容纳包含治疗剂的液体的储存器和与储存器流体连通的套管。套管被成形为便于将其插入患者眼球。

10. 发明申请

US20080039792A1 MEMS DEVICE AND METHOD FOR DELIVERY OF THERAPEUTIC AGENTS 有权
标题翻译：用于输送治疗剂的MEMS装置和方法
公开(公告)号：US20080039792A1
公开(公告)日：2008-02-14
申请号：US11686310
申请日：2007-03-14
申请人： Ellis Meng , Yu-Chong Tai , Mark Humayun , Rajat Agrawal , Ronalee Lo , Jason Shih , Kenrick Kuwahara , Po-Ying Li , Damien Rodger , Po-Jui Chen
发明人： Ellis Meng , Yu-Chong Tai , Mark Humayun , Rajat Agrawal , Ronalee Lo , Jason Shih , Kenrick Kuwahara , Po-Ying Li , Damien Rodger , Po-Jui Chen
IPC分类号： A61M5/00
CPC分类号： A61F9/0017 , A61K9/0024 , A61K9/0097 , A61M5/14276 , A61M5/14593 , A61M5/155 , A61M5/16877 , A61M5/16881 , A61M37/00 , A61M2005/14204 , A61M2205/0244 , A61M2205/3507 , A61M2207/00 , A61M2210/0612 , B81B2201/058 , B81C1/00119 , B81C2201/019 , F04B43/043 , F16K99/0001 , F16K99/0005 , F16K99/0034 , F16K99/0057 , F16K2099/008 , F16K2099/0088 , Y10T29/49236
摘要： An implantable device for delivering a therapeutic agent to a patient is provided. The device includes a reservoir configured to contain a liquid comprising the therapeutic agent. The device further includes a cannula in fluid communication with the reservoir. The cannula has an outlet configured to be in fluid communication with the patient. The device further includes a first electrode and a second electrode, at least one of the first electrode and the second electrode is planar. The device further includes a material in electrical communication with the first and second electrodes. A voltage applied between the first electrode and the second electrode produces gas from the material, the gas forcing the liquid to flow from the reservoir to the outlet.
摘要翻译：提供了一种用于将治疗剂递送至患者的可植入装置。该装置包括构造成容纳包含治疗剂的液体的储存器。该装置还包括与储存器流体连通的套管。套管具有被配置成与患者流体连通的出口。该装置还包括第一电极和第二电极，第一电极和第二电极中的至少一个是平面的。该装置还包括与第一和第二电极电连通的材料。施加在第一电极和第二电极之间的电压从材料产生气体，气体迫使液体从储存器流出到出口。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式