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1. 发明申请

US20160254863A1 CIRCUIT ARCHITECTURE AND SYSTEM FOR IMPLANTABLE MULTI-FUNCTION AND MULTI-ANALYTE BIOSENSING DEVICE 审中-公开
标题翻译：可植入多功能和多分析生物传感装置的电路结构和系统
公开(公告)号：US20160254863A1
公开(公告)日：2016-09-01
申请号：US15149908
申请日：2016-05-09
申请人： Faquir C. Jain , Fotios Papadimitrakopoulos , Robert A. Croce, JR. , Pawan Gogna , Syed Kamrul Islam , Liang Zuo , Kai Zhu
发明人： Faquir C. Jain , Fotios Papadimitrakopoulos , Robert A. Croce, JR. , Pawan Gogna , Syed Kamrul Islam , Liang Zuo , Kai Zhu
IPC分类号： H04B10/11 , A61B5/00 , A61B5/145 , G01N27/414
CPC分类号： H04B10/11 , A61B5/0031 , A61B5/14503 , G01N27/4145 , H04B10/1149 , H04J14/02
摘要： An implantable bio-sensing platform architecture that enables the wireless selection, calibration and reading of multiple sensors, as well as checking the power levels of the solar powering source energizing various electronic and optoelectronic devices and circuits embedded in the platform. It also permits checking the operation of the potentiostats interfacing with each amperometric analyte sensor. The platform is flexible to include FET based sensors for protein sensing as well as other applications including pH sensing. In addition, other physiological sensors can be integrated in the platform.
摘要翻译：一种植入式生物传感平台架构，可实现多个传感器的无线选择，校准和读取，以及检查为嵌入在平台中的各种电子和光电子器件和电路通电的太阳能供电源的功率电平。它还允许检查与每个电流分析物传感器连接的恒电位仪的操作。该平台是灵活的，包括基于FET的传感器用于蛋白质感测以及其他应用，包括pH感测。此外，其他生理传感器可以集成在平台中。

2. 发明授权

US08771500B2 Glucose sensors and methods of manufacture thereof 有权
标题翻译：葡萄糖传感器及其制造方法
公开(公告)号：US08771500B2
公开(公告)日：2014-07-08
申请号：US12256043
申请日：2008-10-22
申请人： Fotios Papadimitrakopoulos , Santhisagar Vaddiraju
发明人： Fotios Papadimitrakopoulos , Santhisagar Vaddiraju
IPC分类号： C12Q1/00 , G01N27/26 , G01N33/50 , G01F1/64
CPC分类号： C12Q1/006 , A61B5/14532 , C01B13/0248 , C01B13/0259 , C01B13/0285 , C12Q1/003
摘要： Disclosed herein is a device that functions as a glucose sensor. The device has a reference electrode; a counter electrode, a working electrode; an electrically conducting membrane; an enzyme layer; a semi-permeable membrane; a first layer of a first hydrogel in operative communication with the working electrode; the first layer of the first hydrogel being operative to store oxygen; wherein the amount of stored oxygen is proportional to the number of freeze-thaw cycles that the hydrogel is subjected to; and a second layer of the second hydrogel. Disclosed too is a method that comprises using periodically biased amperometry towards interrogation of implantable glucose sensors to improve both sensor's sensitivity and linearity while at the same time enable internal calibration against sensor drifts that originate from changes in either electrode activity or membrane permeability as a result of fouling, calcification and/or fibrosis.
摘要翻译：这里公开了用作葡萄糖传感器的装置。该装置具有参考电极; 对电极，工作电极; 导电膜; 酶层; 半透膜; 与工作电极操作性连通的第一水凝胶的第一层; 所述第一水凝胶的第一层用于储存氧气; 其中储存的氧气的量与水凝胶经受的冻融循环次数成比例; 和第二层水凝胶。还公开了一种方法，其包括使用周期性偏置的电流分析法来询问可植入的葡萄糖传感器，以改善传感器的灵敏度和线性度，同时对来自电极活性或膜渗透性的变化的传感器漂移进行内部校准，这是由于作为结垢，钙化和/或纤维化。

3. 发明授权

US08698226B2 Semiconductor devices, methods of manufacture thereof and articles comprising the same 有权
标题翻译：半导体装置及其制造方法及其制造方法
公开(公告)号：US08698226B2
公开(公告)日：2014-04-15
申请号：US12533770
申请日：2009-07-31
申请人： Faquir C. Jain , Fotios Papadimitrakopoulos
发明人： Faquir C. Jain , Fotios Papadimitrakopoulos
IPC分类号： H01L29/788
CPC分类号： H01L29/66977 , B82Y10/00 , G01N27/4146 , H01L29/0665 , H01L29/0673 , H01L29/1606 , H01L29/42356 , H01L29/7781 , H01L29/7836
摘要： Disclosed herein is a device comprising a source region, a drain region and a gate layer; the source region, the drain region and the gate layer being disposed on a semiconductor host; the gate layer being disposed between source and drain regions; the gate layer comprising a first gate-insulator layer; a gate layer comprising carbon nanotubes and/or graphene. Disclosed herein too is a method comprising disposing a source region, a drain region and a gate layer on a semiconductor host; the gate layer being disposed between the source region and the drain region; the gate layer comprising carbon nanotubes and/or graphene.
摘要翻译：本文公开了一种包括源极区，漏极区和栅极层的器件; 源极区，漏极区和栅极层设置在半导体主体上; 所述栅极层设置在源极和漏极区之间; 所述栅极层包括第一栅绝缘体层; 包含碳纳米管和/或石墨烯的栅极层。本文还公开了一种方法，其包括在半导体主机上设置源极区域，漏极区域和栅极层; 所述栅极层设置在所述源极区域和所述漏极区域之间; 所述栅极层包括碳纳米管和/或石墨烯。

4. 发明申请

US20100044230A1 METHODS FOR SEPARATING CARBON NANOTUBES 有权
标题翻译：分离碳纳米管的方法
公开(公告)号：US20100044230A1
公开(公告)日：2010-02-25
申请号：US12348631
申请日：2009-01-05
申请人： Fotios Papadimitrakopoulos , Sang-Yong Ju
发明人： Fotios Papadimitrakopoulos , Sang-Yong Ju
IPC分类号： C08F6/00 , C07H21/00 , C07K14/00 , B01D15/34 , B01D15/36 , B01D15/08 , B01D21/26
CPC分类号： B01D15/08 , B01D15/34 , B01D15/363 , B03D3/00 , B82Y30/00 , B82Y40/00 , C01B32/174 , C01B2202/02 , C01B2202/20 , C07H19/207 , Y10S977/742 , Y10S977/751 , Y10S977/842 , Y10S977/845
摘要： Disclosed herein too is a method that includes dispersing nanotubes in media that comprises flavin moieties substituted with solubilizing side chains, and/or non-flavin containing molecular species; self-assembling the flavin moieties and other non-flavin containing molecular species in a pattern that is orderly wrapped around the nanotubes to form a composite; introducing desired amounts of an optional reagent that competes with self-assembly in order to disturb the wrapping around nanotubes with moderate order; and centrifuging the mass of the nanotubes and the composites to extract the composite from other nanotubes that are not in composite form.
摘要翻译：本文还公开了一种方法，其包括将纳米管分散在包含被增溶侧链取代的黄素部分和/或含有非黄素的分子种类的介质中; 以有序地缠绕在纳米管周围形成复合材料的图案自组装黄素部分和其它含有非黄素的分子物质; 引入所需量的与自组装竞争的任选试剂，以便以适度的顺序扰乱纳米管周围的缠绕; 并离心纳米管和复合物的质量以从不是复合形式的其他纳米管中提取复合材料。

5. 发明申请

US20080070354A1 SITE-SPECIFIC NANOPARTICLE SELF-ASSEMBLY 失效
标题翻译：现场特定的纳米材料自组装
公开(公告)号：US20080070354A1
公开(公告)日：2008-03-20
申请号：US11454963
申请日：2006-06-15
申请人： Faquir C. Jain , Fotios Papadimitrakopoulos
发明人： Faquir C. Jain , Fotios Papadimitrakopoulos
IPC分类号： H01L21/338
CPC分类号： H01L21/316 , H01L21/02175 , H01L21/02197 , H01L21/0237 , H01L21/02532 , H01L21/02601 , H01L21/02628 , H01L21/02639 , H01L29/66575 , Y10S977/84
摘要： Disclosed herein are methods of self-assembling nanoparticles on specific sites of a substrate. The method generally includes introducing a p-type dopant species to at least a portion of an n-type substrate or introducing an n-type dopant species to at least a portion of a p-type substrate, wherein the dopant species creates a surface charge opposite in polarity to that of the substrate surface prior to the introducing; contacting the nanoparticles with the surface of the substrate; and self-assembling a layer of the nanoparticles on p-type regions of the substrate. The methods described herein may be used in the formation of sub-22 nanometer channels, which find use in field-effect transistors, electronic chips, nanoscale biosensors, photonic band gap devices, lasers in optoelectronics and photonics chips, as well as nano-electro-mechanical devices (NEMS).
摘要翻译：本文公开了在衬底的特定位点上自组装纳米颗粒的方法。该方法通常包括将p型掺杂剂物质引入n型衬底的至少一部分或将n型掺杂剂物质引入至p型衬底的至少一部分，其中掺杂剂物质产生表面电荷在引入之前极性与基板表面的极性相反; 使纳米颗粒与基底的表面接触; 并且在衬底的p型区域上自组装纳米颗粒层。本文描述的方法可用于形成亚22纳米通道，其用于场效应晶体管，电子芯片，纳米尺度生物传感器，光子带隙器件，光电子学和激光芯片中的激光器以及纳米电子机电设备（NEMS）。

6. 发明授权

US09402574B2 Sensors for analyte detection and methods of manufacture thereof 有权
标题翻译：用于分析物检测的传感器及其制造方法
公开(公告)号：US09402574B2
公开(公告)日：2016-08-02
申请号：US13164656
申请日：2011-06-20
申请人： Liangliang Qiang , Santhisagar Vaddiraju , Fotios Papadimitrakopoulos
发明人： Liangliang Qiang , Santhisagar Vaddiraju , Fotios Papadimitrakopoulos
IPC分类号： A61B5/00 , A61B5/1486 , A61B5/1473
CPC分类号： A61B5/14865 , A61B5/14532 , A61B5/1473 , A61B5/1495 , A61B2560/0223 , A61B2562/028 , A61B2562/0285 , A61B2562/04 , A61B2562/125
摘要： Disclosed herein is a sensor comprising a conduit; the conduit comprising an organic polymer; a working electrode; the working electrode being etched and decorated with a nanostructured material; a reference electrode; and a counter electrode; the working electrode, the reference electrode and the counter electrode being disposed in the conduit; the working electrode, the reference electrode and the counter electrode being separated from each other by an electrically insulating material; and wherein a cross-sectional area of the conduit that comprises a section of the working electrode, a section of the reference electrode and a section of the counter electrode is exposed to detect analytes.
摘要翻译：本文公开了一种传感器，其包括导管; 导管包含有机聚合物; 工作电极工作电极用纳米结构材料进行蚀刻和装饰; 参考电极; 和对电极; 工作电极，参比电极和对电极设置在导管中; 工作电极，参考电极和对电极通过电绝缘材料彼此分离; 并且其中包括所述工作电极的一部分，参考电极的一部分和所述对电极的一部分的所述导管的横截面面积被暴露以检测分析物。

7. 发明授权

US08193430B2 Methods for separating carbon nanotubes 有权
标题翻译：分离碳纳米管的方法
公开(公告)号：US08193430B2
公开(公告)日：2012-06-05
申请号：US12348631
申请日：2009-01-05
申请人： Fotios Papadimitrakopoulos , Sang-Yong Ju
发明人： Fotios Papadimitrakopoulos , Sang-Yong Ju
IPC分类号： B01D21/26 , C02F1/38
CPC分类号： B01D15/08 , B01D15/34 , B01D15/363 , B03D3/00 , B82Y30/00 , B82Y40/00 , C01B32/174 , C01B2202/02 , C01B2202/20 , C07H19/207 , Y10S977/742 , Y10S977/751 , Y10S977/842 , Y10S977/845
摘要： Disclosed herein too is a method that includes dispersing nanotubes in media that comprises flavin moieties substituted with solubilizing side chains, and/or non-flavin containing molecular species; self-assembling the flavin moieties and other non-flavin containing molecular species in a pattern that is orderly wrapped around the nanotubes to form a composite; introducing desired amounts of an optional reagent that competes with self-assembly in order to disturb the wrapping around nanotubes with moderate order; and centrifuging the mass of the nanotubes and the composites to extract the composite from other nanotubes that are not in composite form.
摘要翻译：本文还公开了一种方法，其包括将纳米管分散在包含被增溶侧链取代的黄素部分和/或含有非黄素的分子种类的介质中; 以有序地缠绕在纳米管周围形成复合材料的图案自组装黄素部分和其它含有非黄素的分子物质; 引入所需量的与自组装竞争的任选试剂，以便以适度的顺序扰乱纳米管周围的缠绕; 并离心纳米管和复合物的质量以从不是复合形式的其他纳米管中提取复合材料。

8. 发明授权

US07115168B2 Patterned thin-film deposition using collimating heated masked assembly 失效
标题翻译：使用准直加热屏蔽组件的图案化薄膜沉积
公开(公告)号：US07115168B2
公开(公告)日：2006-10-03
申请号：US11045034
申请日：2005-05-03
申请人： Daniel Harrison Grantham , Thomas Samuel Phely-Bobin , Fotios Papadimitrakopoulos , Faquir C. Jain
发明人： Daniel Harrison Grantham , Thomas Samuel Phely-Bobin , Fotios Papadimitrakopoulos , Faquir C. Jain
IPC分类号： C23C14/04
CPC分类号： C23C14/044 , C23C14/22 , H01L51/001
摘要： Scanning localized evaporation and deposition of an evaporant on a substrate utilizes a mask assembly comprised of a series of mask elements with openings thereon and spaced apart in a stack. The openings are aligned so as to direct the evaporant therethrough onto the substrate. The mask elements are heated and the stack may include a movable shutter element to block openings in adjacent mask elements. The evaporant streams are usually vertical but some may be oblique to the substrate, and they may be of different materials.
摘要翻译：将蒸发器的局部蒸发和沉积扫描在基底上使用掩模组件，该掩模组件由其上具有开口的一系列掩模元件组成并且在堆叠中间隔开。开口对准，以将蒸发器引导到基板上。掩模元件被加热并且堆叠可以包括可移动的快门元件以阻挡相邻的掩模元件中的开口。蒸发剂流通常是垂直的，但是一些可以与衬底倾斜，并且它们可以是不同的材料。

9. 发明申请

US20060118047A1 Single-pass growth of multilayer patterned electronic and photonic devices using a scanning localized evaporation methodology (SLEM) 失效
标题翻译：使用扫描局部蒸发方法（SLEM）的多层图案化电子和光子器件的单通道生长
公开(公告)号：US20060118047A1
公开(公告)日：2006-06-08
申请号：US11327756
申请日：2006-01-09
申请人： Fotios Papadimitrakopoulos , Thomas Phely-Bobin , Deniel Grantham , Faquir Jain
发明人： Fotios Papadimitrakopoulos , Thomas Phely-Bobin , Deniel Grantham , Faquir Jain
IPC分类号： C23C16/00
CPC分类号： C23C14/042 , C23C14/246 , C23C14/26 , C23C14/568 , H01L51/56
摘要： The invention decribes an apparatus, Scanning Localized Evaporation Methodology (SLEM) for the close proximity deposition of thin films with high feature definition, high deposition rates, and significantly improved material economy. An array of fixed thin film heating elements, each capable of being individually energized, is mounted on a transport mechanism inside a vacuum chamber. The evaporable material is deposited on a heating element. The SLEM system loads the surface of heating elements, made of foils, with evaporable material. The loaded thin film heating element is transported to the substrate site for re-evaporation. The re-evaporation onto a substrate, which is maintained at the desired temperature, takes place through a mask. The mask, having patterned openings dictated by the structural requirements of the fabrication, may be heated to prevent clogging of the openings. The translation of the substrate past the evaporation site permits replication of the pattern over its entire surface. A multiplicity of fixed thin film heating element arrays is provided that can operate simultaneously or in sequence. Multi-layered structures of evaporable materials with high in-plane spatial pattern resolution can be deposited using this apparatus. In one version of the invention, the transport of the evaporant-loaded thin film heating elements is accomplished by the use of cylindrical rotors on whose circumference the heating elements are mounted.
摘要翻译：本发明描述了用于紧密沉积具有高特征定义，高沉积速率和显着改善的材料经济性的薄膜的扫描定位蒸发方法（SLEM）的装置。一组固定的薄膜加热元件，每个固定的薄膜加热元件均能分别通电，安装在真空室内的输送机构上。蒸发材料沉积在加热元件上。 SLEM系统用可蒸发材料加载由箔制成的加热元件的表面。负载的薄膜加热元件被输送到基底部位以进行再蒸发。通过掩模将保持在所需温度下的基底上的再蒸发发生。可以加热具有由制造的结构要求所规定的图案化开口的掩模，以防止开口堵塞。衬底经过蒸发位置的平移允许在其整个表面上复制图案。提供了可以同时或依次操作的多个固定薄膜加热元件阵列。可以使用该装置沉积具有高面内空间图案分辨率的蒸发材料的多层结构。在本发明的一个实施例中，通过使用圆周转子来实现蒸发负载的薄膜加热元件的输送，圆柱形转子的圆周上装有加热元件。

10. 发明申请

US20050006656A1 Full color display structures using pseudomorphic cladded quantum dot nanophosphor thin films 失效
标题翻译：全彩色显示结构使用伪形包层量子点纳米荧光体薄膜
公开(公告)号：US20050006656A1
公开(公告)日：2005-01-13
申请号：US10805070
申请日：2004-03-22
申请人： Faquir Jain , Fotios Papadimitrakopoulos
发明人： Faquir Jain , Fotios Papadimitrakopoulos
IPC分类号： C09K11/02 , C09K11/08 , C09K11/64 , C09K11/88 , H01L33/18 , H05B33/14 , H05B33/00
CPC分类号： B82Y30/00 , B82Y20/00 , C09K11/025 , C09K11/0883 , C09K11/64 , C09K11/883 , H01L33/18 , H05B33/14 , Y10S428/917 , Y10S977/952
摘要： This invention discloses novel device structures for full color flat panel displays utilizing pseudomorphically cladded quantum dot nanocrystals. Different colors are obtained by changing the core size and composition of the quantum dots while maintaining a nearly defect-free lattice at the core-cladding interface. Light emission from the quantum dot core is obtained either by injection or by avalanche electroluminescence. A nanotip emitter device is also presented. These generic devices can be addressed using a variety of conventional display drivers, including active and passive matrix configurations.
摘要翻译：本发明公开了利用假构造的量子点纳米晶体的全彩平板显示器的新型器件结构。通过改变核心尺寸和量子点的组成，同时在芯 - 包层界面处保持几乎无缺陷的晶格，可获得不同的颜色。通过注射或雪崩电致发光获得量子点核的发光。还提出了一种纳米尖端发射器件。这些通用设备可以使用各种常规显示驱动器来解决，包括主动和被动矩阵配置。

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