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1. 发明授权

US08431349B2 Compositions and methods for early pregnancy diagnosis 有权
标题翻译：早孕诊断的组成和方法
公开(公告)号：US08431349B2
公开(公告)日：2013-04-30
申请号：US12747514
申请日：2008-12-12
申请人： Nagappan Mathialagan , Robert M. Roberts , Michael F. McGrath , Jonathan Green
发明人： Nagappan Mathialagan , Robert M. Roberts , Michael F. McGrath , Jonathan Green
IPC分类号： G01N33/53 , C12N5/20 , C07K16/42 , C07K16/24
CPC分类号： G01N33/6803 , C07K16/18 , G01N2333/471
摘要： Disclosed are antibodies and methods for detecting pregnancy in an animal. In certain aspects antibodies used binds immunologically to at least two PAGs selected from PAG4, PAG6, PAG9, PAG16, PAG17, PAG19, PAG20 and PAG21. Antibody encoding nucleic acids are also provided, as are kits, methods of use and additional antibody related compositions.
摘要翻译：公开了用于在动物中检测怀孕的抗体和方法。在某些方面，使用的抗体与选自PAG4，PAG6，PAG9，PAG16，PAG17，PAG19，PAG20和PAG21的至少两种PAG免疫结合。还提供抗体编码核酸，试剂盒，使用方法和另外的抗体相关组合物。

2. 外观设计

USD675047S1 Rolled paper product dispenser 有权
标题翻译：卷纸产品分配器
公开(公告)号：USD675047S1
公开(公告)日：2013-01-29
申请号：US29408992
申请日：2011-12-19
申请人： Jonathan Green , Bastiaan Roelof Tjaden , Joseph Elisabeth Oberdorf
设计人： Jonathan Green , Bastiaan Roelof Tjaden , Joseph Elisabeth Oberdorf

3. 外观设计

USD674223S1 Paper product dispenser 有权
公开(公告)号：USD674223S1
公开(公告)日：2013-01-15
申请号：US29408989
申请日：2011-12-19
申请人： Jonathan Green , Bastiaan Roelof Tjaden , Joseph Elisabeth Oberdorf
设计人： Jonathan Green , Bastiaan Roelof Tjaden , Joseph Elisabeth Oberdorf

4. 发明申请

US20110195769A1 METHOD AND APPARATUS FOR LIMITING PRIZE LIABILITY IN A GAME OF CHANCE 审中-公开
标题翻译：限制游戏机会中的评估责任的方法和装置
公开(公告)号：US20110195769A1
公开(公告)日：2011-08-11
申请号：US12703973
申请日：2010-02-11
申请人： Michael D. Frick , Mark Davis , Timothy Patrick Jonathan Green
发明人： Michael D. Frick , Mark Davis , Timothy Patrick Jonathan Green
IPC分类号： A63F9/24 , A63F13/00
CPC分类号： G07F17/3244
摘要： A process generates, with a game of chance entry generation apparatus, a plurality of game of chance entries such that (i) each game of chance entry provides a game of chance player with an opportunity to play the game of chance and (ii) the game of chance provides a plurality of offered non-cash prizes such that a cost in cash incurred by a game of chance operator for a plurality of redeemed non-cash prizes, which is a subset of the plurality of offered non-cash prizes, is less than a fair market value of purchasing the plurality of offered non-cash prizes as a result of the cost in cash incurred by the game of chance operator being calculated on a basis of an estimated redemption of the plurality of offered non-cash prizes being less than a full redemption of the plurality of offered non-cash prizes.
摘要翻译：一个进程通过机会进入生成装置的游戏产生多个机会条目游戏，使得（i）每个机会进入游戏提供机会玩家的游戏机会玩机会的游戏，以及（ii）机会游戏提供多个提供的非现金奖励，使得机会运算符对于作为多个提供的非现金奖品的子集的多个被兑换的非现金奖品所产生的现金成本是由于机会经营者的游戏所产生的现金成本是根据多个所提供的非现金奖励的估计赎回而计算的，购买多个提供的非现金奖品的公平市场价值不足少于全面赎回多项提供的非现金奖励。

5. 发明申请

US20110119332A1 MOVEMENT ANIMATION METHOD AND APPARATUS 审中-公开
标题翻译：运动动画方法和装置
公开(公告)号：US20110119332A1
公开(公告)日：2011-05-19
申请号：US12774528
申请日：2010-05-05
申请人： Steve Marshall , Geroge Richard Alexander , Rocco Localszo , Paul Tempest , Jonathan Green , Malcolm Ian Clark
发明人： Steve Marshall , Geroge Richard Alexander , Rocco Localszo , Paul Tempest , Jonathan Green , Malcolm Ian Clark
IPC分类号： G06F15/16
CPC分类号： A63F13/355 , A63F13/10 , A63F13/12 , A63F13/77 , A63F2300/538 , A63F2300/552 , A63F2300/6607 , G06T13/00 , G06T2200/16
摘要： The invention relates to methods and apparatus for movement animation of a user-controlled entity in a virtual environment. Entity tracking data is stored on a server in order to track movement of the entity in the virtual environment. A user may input a desired action for their entity via a client, which is transmitted from the client to the server. The server uses the received data to select an appropriate animation for the entity. The server then transmits data identifying the selected animation to the client, thus controlling animation of the entity on the client. By using animation data to simulate movement of the entity, along with keeping an accurate representation of the movement of the entity in the virtual environment, the server may control the entity accurately and therefore animation of the entity may be more realistic.
摘要翻译：本发明涉及用于在虚拟环境中移动用户控制实体的动画的方法和装置。实体跟踪数据存储在服务器上，以便跟踪虚拟环境中实体的移动。用户可以经由客户端向服务器发送的客户端为其实体输入所需的动作。服务器使用接收到的数据为实体选择适当的动画。然后，服务器将识别所选动画的数据发送给客户端，从而控制客户端上的实体的动画。通过使用动画数据来模拟实体的移动，以及保持实体在虚拟环境中的移动的准确表示，服务器可以准确地控制实体，因此实体的动画可能更加现实。

6. 发明申请

US20090258375A1 ASSAYS FOR DETECTING PREGNANCY-ASSOCIATED GLYCOPROTEINS 有权
标题翻译：用于检测与孕激素相关的糖蛋白的测定
公开(公告)号：US20090258375A1
公开(公告)日：2009-10-15
申请号：US12422231
申请日：2009-04-10
申请人： Jonathan Green , Bhanu Prakash Telugu
发明人： Jonathan Green , Bhanu Prakash Telugu
IPC分类号： G01N33/573 , C12Q1/37
CPC分类号： C12Q1/37 , G01N2333/96416 , G01N2800/36
摘要： Disclosed are methods and compositions for detecting pregnancy in an animal by means of assaying peptidase activity of one or more Pregnancy Associated Glycoproteins (PAGs). In certain aspects, methods also comprising use of an antibody that binds immunologically to a PAG that displays proteolytic activity are provided. Substrates of proteolytic PAGs are also provided, as are kits, and methods of use. Further, methods of purifying PAGs based on their proteolytic activity are also provided.
摘要翻译：公开了通过测定一种或多种妊娠相关糖蛋白（PAG）的肽酶活性来检测动物中怀孕的方法和组合物。在某些方面，提供了还包括使用与显示蛋白水解活性的PAG免疫学结合的抗体的方法。还提供蛋白水解PAG的底物，试剂盒和使用方法。此外，还提供了基于其蛋白水解活性来纯化PAG的方法。

7. 发明申请

US20070141626A1 IMMUNOASSAY FOR VENOM DETECTION INCLUDING NONINVASIVE SAMPLE COLLECTION 有权
标题翻译：免疫检测，包括非活动样品收集
公开(公告)号：US20070141626A1
公开(公告)日：2007-06-21
申请号：US11550130
申请日：2006-10-17
申请人： William Stoecker , Hernan Gomez , Jonathan Green , David McGlasson
发明人： William Stoecker , Hernan Gomez , Jonathan Green , David McGlasson
IPC分类号： G01N33/53
CPC分类号： G01N33/5308 , G01N33/5091 , G01N2800/42 , Y10S435/97 , Y10S435/975 , Y10S436/808 , Y10S436/81
摘要： Methods and immunoassays for diagnosing a bite or sting of a venomous organism in a patient having symptoms consistent with such a bite or sting are provided. A sample of venom is collected from the area of the suspected bite or sting using a swab and then contacted with an antibody that specifically binds to an antigenic site on venom present in the sample. Binding is then detected. The invention is illustrated by examples showing diagnosis of brown recluse spider bite, distinguishing it from other diagnoses with which it is often confused. This extremely sensitive test can detect venom antigens down to about 20 picograms even after the sample has been shipped and stored for periods of up to three weeks during the summer.
摘要翻译：提供了用于诊断具有与这种咬合或刺痛一致的症状的患者中的有毒生物的咬伤或刺痛的方法和免疫测定。使用拭子从怀疑咬伤或刺痛的区域收集毒液样品，然后与特异性结合样品中存在的毒液上的抗原位点的抗体接触。然后检测绑定。本发明通过示出棕色隐窝蜘蛛咬伤诊断的实例进行说明，将其与常常混淆的其他诊断区分开来。这种非常敏感的测试可以检测到毒液抗原降至20皮克，甚至在样品运输后，在夏天存放长达三周的时间。

8. 发明申请

US20050014726A1 Pharmaceutical composition for use for the treatment of malignancies comprising in combination a bisphosphonates, a cox-2 inhibitor and a taxol 失效
标题翻译：用于治疗恶性肿瘤的药物组合物，其包含双膦酸盐，cox-2抑制剂和紫杉醇的组合
公开(公告)号：US20050014726A1
公开(公告)日：2005-01-20
申请号：US10493042
申请日：2002-10-18
申请人： Jonathan Green , Allan Lipton , Lois Witters
发明人： Jonathan Green , Allan Lipton , Lois Witters
IPC分类号： A61K31/335 , A61K31/337 , A61K31/365 , A61K31/415 , A61K31/42 , A61K31/444 , A61K31/635 , A61K31/66 , A61K31/663 , A61K45/06 , A61P29/00 , A61P35/00 , A61P43/00
CPC分类号： A61K45/06 , A61K31/335 , A61K31/337 , A61K31/365 , A61K31/415 , A61K31/42 , A61K31/635 , A61K31/66 , A61K2300/00
摘要： A pharmaceutical composition for treatment of malignancies, in particular a malignant disease which is associated with the development of bone metastases or excessive bone resorption, comprises in combination a bisphosphonates, COX-2 inhibitor and/or a taxol or derivative thereof for simultaneous, sequential or separate use. Also provided is a method of treating a patient suffering from a malignant disease comprising administering to the patient an effective amount of a bisphosphonates, an effective amount of a COX-2 inhibitor and/or and effective amount of a taxol or derivative thereof.
摘要翻译：用于治疗恶性肿瘤的药物组合物，特别是与骨转移或过度骨吸收发展有关的恶性疾病包括联合使用双膦酸盐，COX-2抑制剂和/或紫杉醇或其衍生物，用于同时，顺序或单独使用。还提供了治疗患有恶性疾病的患者的方法，包括向患者施用有效量的双膦酸盐，有效量的COX-2抑制剂和/或有效量的紫杉醇或其衍生物。

9. 发明授权

US6057306A Method of treating the navicular disease in horses 失效
标题翻译：马匹治疗舟状病的方法
公开(公告)号：US6057306A
公开(公告)日：2000-05-02
申请号：US43842
申请日：1998-05-15
申请人： Alan Martin Wilson , Allen Edward Goodship , Jonathan Green
发明人： Alan Martin Wilson , Allen Edward Goodship , Jonathan Green
IPC分类号： A61K31/66 , A61K31/00 , A61K31/662 , A61K31/663 , A61P21/00
CPC分类号： A61K31/663
摘要： The invention relates to a method of treating the navicular disease in horses, which comprises treating the navicular disease in horses with an effective amount of at least one compound of formula (I), ##STR1## wherein R.sub.1 is hydrogen, hydroxy, amino or halogen, and R.sub.2 is hydrogen, halogen or a radical which is bound through C, N, S or O, or of a C.sub.1 -C.sub.4 tetraalkyl ester thereof, each in the free form or in the form of the salt and/or in the hydrate form; to a compound of formula (I) for use in a method of treating the navicular disease, to a composition for use in a method of treating the navicular disease, which comprises one or more than one compound of formula (I), as well as to the use of a compound of formula (I) for the preparation of a veterinary composition for treating the navicular disease.
摘要翻译： PCT No.PCT / EP96 / 04161 Sec。 371日期：1998年5月15日 102（e）日期1998年5月15日PCT提交1996年9月24日PCT公布。公开号WO97 / 12619 日期1997年04月10日本发明涉及治疗马的舟状病的方法，其包括用有效量的至少一种式（I）化合物治疗马中的舟状疾病，其中R 1是氢，羟基，氨基或卤素，并且R 2是氢，卤素或通过C，N，S或O或其C1-C4四烷基酯结合的基团，每个以游离形式或以盐的形式和/或水合物形式; 涉及用于治疗舟状病的方法的式（I）化合物，其用于治疗舟状病的方法中使用的组合物，其包含一种或多种式（I）的化合物，以及涉及使用式（I）化合物来制备用于治疗舟状病的兽用组合物。

10. 外观设计

USD698151S1 Container 有权
公开(公告)号：USD698151S1
公开(公告)日：2014-01-28
申请号：US29420067
申请日：2012-05-04
申请人： Kelly D. Arehart , Victoria Brown , Jonathan Green , Darren John Hubbert , Todd James Huthmaker , James Garfield Pryor , Bradley M. Reynolds , Matthew Walton
设计人： Kelly D. Arehart , Victoria Brown , Jonathan Green , Darren John Hubbert , Todd James Huthmaker , James Garfield Pryor , Bradley M. Reynolds , Matthew Walton

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