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1. 发明授权

US10328208B2 Blow-molded syringe for use with an injector 有权
公开(公告)号：US10328208B2
公开(公告)日：2019-06-25
申请号：US15032425
申请日：2014-10-31
申请人： BAYER HEALTHCARE LLC
发明人： Edward J. Rhinehart , Kevin P. Cowan , Mark Trocki , Barry L. Tucker
IPC分类号： A61M5/178 , A61M5/315 , B29B11/14 , B29C49/18 , B29C49/12 , B29L31/00
摘要： A syringe for use in pressurized injection of a fluid is provided herein. The syringe includes a syringe barrel comprising a polymeric material having undergone expansion by stretch blow molding and by compression molding of an inner diameter of the barrel with a core member. In certain configurations of the syringe barrel, the stretch blow molding is provided through a nozzle of the syringe. Similarly, according to a further embodiment, a syringe for use in pressurized injection of a fluid is provided. The syringe includes a syringe barrel comprising a polymeric material having undergone expansion by stretch blow molding and by shrinking an inner diameter of the syringe barrel about a core member.

2. 发明授权

US10583256B2 Syringe with rolling diaphragm 有权
公开(公告)号：US10583256B2
公开(公告)日：2020-03-10
申请号：US15305285
申请日：2015-04-24
申请人： BAYER HEALTHCARE LLC
发明人： Dave Berry , Barry L. Tucker , Edward J. Rhinehart , Gerald W. Callan , Arthur E. Uber, III , Kevin P. Cowan , Raymond C. Hoffman , Benjamin T. Krupp , Martin J. Gibler , Michael A. Spohn
IPC分类号： A61M5/315 , A61M5/24
摘要： A syringe for a fluid delivery system includes a pressure jacket having a distal end, a proximal end, and a throughbore therebetween. The syringe further includes a rolling diaphragm having a proximal end with an end wall for engaging a plunger, a distal end received within the throughbore of the pressure jacket. A sidewall extends between the proximal end and the distal end of the rolling diaphragm along a longitudinal axis. At least a portion of one of the sidewall and the end wall has non-uniform thickness. At least a portion of the sidewall is flexible and rolls upon itself when acted upon by the plunger such that an outer surface of the sidewall at a folding region is folded in a radially inward direction as the plunger is advanced from the proximal end to the distal end of the rolling diaphragm.

3. 发明授权

US09480797B1 System and method for syringe plunger engagement with an injector 有权
标题翻译：注射器柱塞与注射器接合的系统和方法
公开(公告)号：US09480797B1
公开(公告)日：2016-11-01
申请号：US14925722
申请日：2015-10-28
申请人： BAYER HEALTHCARE LLC
发明人： Michael J. Swantner , Richard A. Seman , Barry L. Tucker , Arthur E. Uber, III , Kevin P. Cowan , James A. Dedig , Christopher D. Capone
IPC分类号： A61M5/145 , A61M5/315
CPC分类号： A61M5/14566 , A61M5/14546 , A61M5/31515 , A61M2005/14573
摘要： A plunger for use with a syringe has a plunger body with a proximal end, a distal end, and a circumferential sidewall extending between the proximal end and the distal end along a plunger longitudinal axis. The plunger further has at least one resiliently deflectable retaining member having a first segment attached to the plunger body and a second segment protruding toward the distal end of the plunger body and deflectable relative to the first segment. The plunger further has at least one actuation member associated with the at least one resiliently deflectable retaining member. The at least one actuation member interacts with a piston to deflect the at least one resiliently deflectable retaining member upon rotation of the plunger relative to the piston. The plunger is engagable with the piston regardless of a rotational orientation of the piston relative to the plunger.
摘要翻译：用于注射器的柱塞具有柱塞本体，其具有近端，远端和沿着柱塞纵向轴线在近端和远端之间延伸的周向侧壁。柱塞还具有至少一个可弹性偏转的保持构件，其具有附接到柱塞本体的第一段和朝向柱塞体的远端突出并相对于第一段可偏转的第二段。柱塞还具有与至少一个可弹性偏转的保持构件相关联的至少一个致动构件。所述至少一个致动构件与活塞相互作用，以在所述柱塞相对于所述活塞旋转时偏转所述至少一个可弹性偏转的保持构件。无论活塞相对于柱塞的旋转取向如何，柱塞可与活塞接合。

4. 发明授权

US11129934B2 Self-orienting pressure jacket and pressure jacket-to-injector interface 有权
公开(公告)号：US11129934B2
公开(公告)日：2021-09-28
申请号：US15522496
申请日：2015-10-28
申请人： BAYER HEALTHCARE LLC
发明人： Kevin P. Cowan , Barry L. Tucker , Arthur E. Uber, III , Edward J. Rhinehart , Michael A. Spohn , James R. Neill , Glen P. Williams
IPC分类号： A61M5/14 , A61M5/145 , A61M5/00 , A61M39/10 , A61M5/315
摘要： A pressure jacket for use with a fluid injector includes a barrel having a distal end, a proximal end, and a sidewall extending between the distal end and the proximal end along a longitudinal axis. The pressure jacket includes at least one engagement member protruding from a terminal portion of the proximal end of the barrel in a proximal direction along the longitudinal axis. The at least one engagement member tapers axially in a direction from the distal end toward the proximal end of the barrel. The at least one engagement member engages with a locking mechanism on the fluid injector to releasably lock the pressure jacket with the fluid injector. A taper of the at least one engagement member rotationally guides the barrel into self-alignment with the locking mechanism and axially ejects the barrel upon rotation of the barrel about the longitudinal axis.

5. 发明授权

US10105491B2 Collapsible syringe for fluid delivery system 有权
公开(公告)号：US10105491B2
公开(公告)日：2018-10-23
申请号：US14935654
申请日：2015-11-09
申请人： BAYER HEALTHCARE LLC
发明人： Eugene A. Gelblum , Edward J. Rhinehart , Barry L. Tucker , Mark Trocki , John Puskar-Pasewicz , Matthew Beale , Matthew Sass
IPC分类号： A61M5/178 , A61M5/24 , A61M5/145 , A61M5/148 , B29C49/06 , B29C49/10 , B29K101/12 , B29K105/00 , B29L31/00
摘要： A collapsible syringe assembly for a fluid delivery system is a multi-component device that includes a cylindrical pressure jacket and a collapsible syringe that is received within the pressure jacket. The collapsible syringe includes a cap member and a compressible or deformable sidewall member. The collapsible syringe in one embodiment is adapted to be secured to the pressure jacket by the cap member. The cap member is formed with a discharge port, which may be formed as conventional luer fitting. The discharge port is disposed coaxially within an annular wall on the outward facing side of the cap member and may be recessed within the annular wall.

6. 发明授权

US09517305B2 Medical fluid injector 有权
标题翻译：医用液体注射器
公开(公告)号：US09517305B2
公开(公告)日：2016-12-13
申请号：US13839864
申请日：2013-03-15
申请人： BAYER HEALTHCARE LLC
发明人： Martin J. Uram , Michael J. Yanniello , Barry L. Tucker , David A. Mishler , Edward J. Rhinehart , Mark Trocki , Arthur E. Uber, III , Kevin P. Cowan , John A. Brosovich
IPC分类号： A61M5/172 , A61M5/145 , A61M5/168
CPC分类号： A61M5/1723 , A61M5/1452 , A61M5/14566 , A61M5/16877 , A61M2205/18 , A61M2205/3576 , A61M2205/502 , A61M2205/52 , A61M2230/005
摘要： Systems and methods for intelligently delivering fluid to a targeted tissue. The systems and methods may include directing a pump to distribute fluid to a targeted tissue and receiving one or more signals from an intracorporeal sensing system, where the one or more signals correspond to one or more sensed feedback parameters at the targeted tissue. The systems and methods may also include determining whether the one or more sensed feedback parameters are within an acceptable range. If the one or more sensed feedback parameters are not within the acceptable range, the systems and methods may include determining an adjusted velocity for the plunger necessary to adjust the pressure of the fluid in the pump so that the one or more sensed feedback parameters move within the acceptable range and directing the pump to distribute the fluid at the adjusted velocity.
摘要翻译：将流体智能输送到目标组织的系统和方法。系统和方法可以包括引导泵将流体分配到目标组织并从体内感测系统接收一个或多个信号，其中一个或多个信号对应于目标组织处的一个或多个感测到的反馈参数。系统和方法还可以包括确定一个或多个感测到的反馈参数是否在可接受的范围内。如果一个或多个感测到的反馈参数不在可接受的范围内，则系统和方法可以包括确定用于调节泵中的流体压力所需的柱塞的调节速度，使得一个或多个感测到的反馈参数在可接受的范围并引导泵以调节的速度分配流体。

7. 发明申请

US20160151565A1 FLUID CONTAINER DISPLACEMENT PUMP 审中-公开
标题翻译：流体容器位移泵
公开(公告)号：US20160151565A1
公开(公告)日：2016-06-02
申请号：US14903344
申请日：2014-07-10
申请人： BAYER HEALTHCARE LLC
发明人： Kevin P. Cowan , Barry L. Tucker , Edward J. Rhinehart
IPC分类号： A61M5/145
CPC分类号： A61M5/1452 , A61M5/14216 , A61M5/148 , A61M5/16854 , A61M2005/14533 , A61M2205/10 , G05D7/0676
摘要： A fluid container displacement pump, in one embodiment, includes a pump housing defining a pump chamber for holding a fluid to be dispensed to a patient, at least one actuating member movable relative to the pump housing and extending through at least one opening defined in the pump housing, and a cover member disposed in the pump chamber opposite the actuating member. The fluid container displacement pump, in another embodiment, includes a pump housing defining a pump chamber for holding a fluid to be dispensed to a patient, at least one actuating member movable relative to the pump housing and extending through at least one opening defined in the pump housing, a fluid reservoir defining a reservoir chamber in fluid communication with the pump housing, and a control valve controlling fluid flow between the reservoir chamber and the pump chamber.
摘要翻译：在一个实施例中，流体容器排量泵包括限定用于保持要分配给患者的流体的泵室的泵壳体，至少一个致动构件，其可相对于泵壳体移动并且延伸通过限定在所述泵壳体中的至少一个开口泵壳体，以及设置在泵室中与致动构件相对的盖构件。在另一个实施例中，流体容器移动泵包括限定用于保持要分配给患者的流体的泵室的泵壳体，至少一个可相对于泵壳体移动的致动构件，并且延伸穿过至少一个开口泵壳体，限定与泵壳体流体连通的储存室的流体储存器以及控制储存室和泵室之间的流体流动的控制阀。

8. 发明授权

US10792418B2 Self-orienting pressure jacket and pressure jacket-to-injector interface 有权
公开(公告)号：US10792418B2
公开(公告)日：2020-10-06
申请号：US15522438
申请日：2015-10-28
申请人： BAYER HEALTHCARE LLC
发明人： Barry L. Tucker , Kevin P. Cowan , Arthur E. Uber, III , Edward J. Rhinehart , Michael A. Spohn
IPC分类号： A61M5/00 , A61M5/145 , A61M5/315 , A61M39/10
摘要： A pressure jacket includes a barrel having a proximal end, a distal end, and a sidewall extending substantially circumferentially between the proximal end and the distal end along a longitudinal axis. The pressure jacket also includes at least one retaining member having at least one first lug protruding radially outward relative to an outer surface of the sidewall. The at least one first lug has at least one third surface tapered axially relative to the longitudinal axis of the barrel in a proximal direction. The at least one first lug is configured for engagement with a locking mechanism associated with a port on a fluid injector to releasably lock the pressure jacket with the fluid injector. At least a portion of the at least one third surface axially ejects the pressure jacket upon rotation of the pressure jacket about the longitudinal axis.

9. 发明授权

US10589018B2 Multi-dose disposable system 有权
公开(公告)号：US10589018B2
公开(公告)日：2020-03-17
申请号：US15119467
申请日：2015-02-18
申请人： Bayer HealthCare LLC
发明人： Arthur E. Uber, III , Ralph H. Schriver , Barry L. Tucker , James A. Dedig
IPC分类号： A61M5/00 , A61M5/14 , A61M5/142 , A61M5/145 , A61M39/22 , A61M39/24 , A61M39/26 , A61M39/00
摘要： A multi-dose disposable fluid delivery system includes at least one fluid container, a multi-use fluid path set, and a plurality of single-use fluid path sets. The at least one fluid container has a connection port configured for fluidly connecting with a first end of the multi-use fluid path set. The second end of the multi-fluid path set is configured for fluidly connecting to a fluid injection apparatus. The plurality of single-use fluid path sets is connected in sequence to define a fluid path extending from a first single-use fluid path set to a last single- use fluid path set. Each of the plurality single-use fluid path sets has a first end and a second end. The first end of the first single-use fluid path set is configured for connecting to a delivery line. The second end of the last single-use fluid path set is configured for connecting to the injection apparatus.

10. 发明授权

US10478558B2 Medical fluid injector 有权
公开(公告)号：US10478558B2
公开(公告)日：2019-11-19
申请号：US15375481
申请日：2016-12-12
申请人： BAYER HEALTHCARE LLC
发明人： Martin J. Uram , Michael J. Yanniello , Barry L. Tucker , David A. Mishler , Edward J. Rhinehart , Mark Trocki , Arthur E. Uber, III , Kevin P. Cowan , John A. Brosovich
IPC分类号： A61M5/172 , A61M5/145 , A61M5/168
摘要： Systems and methods for intelligently delivering fluid to a targeted tissue are described. The systems and methods may include directing a pump to distribute fluid to a targeted tissue and receiving one or more signals from an intracorporeal sensing system, where the one or more signals correspond to one or more sensed feedback parameters at the targeted tissue. The systems and methods may also include determining whether the one or more sensed feedback parameters are within an acceptable range. If the one or more sensed feedback parameters are not within the acceptable range, the systems and methods may include determining an adjusted velocity for the plunger necessary to adjust the pressure of the fluid in the pump so that the one or more sensed feedback parameters move within the acceptable range and directing the pump to distribute the fluid at the adjusted velocity.

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