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1. 发明授权

US11202898B2 Fluid path set bolus control device 有权
公开(公告)号：US11202898B2
公开(公告)日：2021-12-21
申请号：US16600961
申请日：2019-10-14
申请人： BAYER HEALTHCARE LLC
发明人： Ralph Schriver , James A. Dedig
IPC分类号： A61M39/24 , A61M5/168 , A61M39/10 , A61M39/22 , A61M5/142
摘要： A bolus control device for use with an injection device, the bolus control device including a valve body having a proximal end opposite a distal end. The valve body defines a fluid channel therethrough to allow a passage of medical fluid from the proximal end to the distal end. A connector is provided at the proximal end and configured for connecting to a fluid inlet line. A connector subassembly is provided at the distal end and configured for connecting to a fluid outlet line. A compressible check valve is disposed within the fluid channel, such that the compressible check valve is adjustable to control a cracking pressure at which the compressible check valve closes.

2. 发明授权

US09480797B1 System and method for syringe plunger engagement with an injector 有权
标题翻译：注射器柱塞与注射器接合的系统和方法
公开(公告)号：US09480797B1
公开(公告)日：2016-11-01
申请号：US14925722
申请日：2015-10-28
申请人： BAYER HEALTHCARE LLC
发明人： Michael J. Swantner , Richard A. Seman , Barry L. Tucker , Arthur E. Uber, III , Kevin P. Cowan , James A. Dedig , Christopher D. Capone
IPC分类号： A61M5/145 , A61M5/315
CPC分类号： A61M5/14566 , A61M5/14546 , A61M5/31515 , A61M2005/14573
摘要： A plunger for use with a syringe has a plunger body with a proximal end, a distal end, and a circumferential sidewall extending between the proximal end and the distal end along a plunger longitudinal axis. The plunger further has at least one resiliently deflectable retaining member having a first segment attached to the plunger body and a second segment protruding toward the distal end of the plunger body and deflectable relative to the first segment. The plunger further has at least one actuation member associated with the at least one resiliently deflectable retaining member. The at least one actuation member interacts with a piston to deflect the at least one resiliently deflectable retaining member upon rotation of the plunger relative to the piston. The plunger is engagable with the piston regardless of a rotational orientation of the piston relative to the plunger.
摘要翻译：用于注射器的柱塞具有柱塞本体，其具有近端，远端和沿着柱塞纵向轴线在近端和远端之间延伸的周向侧壁。柱塞还具有至少一个可弹性偏转的保持构件，其具有附接到柱塞本体的第一段和朝向柱塞体的远端突出并相对于第一段可偏转的第二段。柱塞还具有与至少一个可弹性偏转的保持构件相关联的至少一个致动构件。所述至少一个致动构件与活塞相互作用，以在所述柱塞相对于所述活塞旋转时偏转所述至少一个可弹性偏转的保持构件。无论活塞相对于柱塞的旋转取向如何，柱塞可与活塞接合。

3. 发明授权

US11007118B2 Syringe fill adapter 有权
公开(公告)号：US11007118B2
公开(公告)日：2021-05-18
申请号：US15778350
申请日：2016-11-23
申请人： BAYER HEALTHCARE LLC
发明人： Kevin Cowan , James A. Dedig , Michael Spohn , Michael McDermott , Matthew McGee
IPC分类号： A61M5/30 , A61J1/20 , A61J1/14 , A61M37/00 , A61M5/32 , B67D7/60 , B65D5/72
摘要： A fill adapter for delivery of a medical liquid to a container has a body with a distal end, a proximal end, and a central bore extending between the distal end and the proximal end along a longitudinal axis. The central bore has an angled portion at the proximal end of the body such that a diameter of the central portion increases at the angled portion in a direction from the distal end to the proximal end. The fill adapter further has a flow controller disposed within the central bore at a distal end of the angled portion such that a gap is formed between an outer surface of the flow controller and an inner surface of the central bore. The flow controller is shaped to direct liquid flowing through the central bore to flow through the gap and along the angled portion of the central bore under a Coandă effect.

4. 发明授权

US10029220B2 Fluid path set with turbulent mixing chamber, back flow compensator 有权
公开(公告)号：US10029220B2
公开(公告)日：2018-07-24
申请号：US15417945
申请日：2017-01-27
申请人： BAYER HEALTHCARE LLC
发明人： Ralph H. Schriver , Andreas Maihoefer , James A. Dedig , Michael A. Spohn , Herbert M. Grubic , Michael J. Swantner , Adam Caruso
IPC分类号： B01F5/06 , B01F15/00 , B01F3/08 , A61M5/00 , A61M5/168 , A61M39/10 , B01F5/00 , A61M39/00
摘要： A fluid path set includes a first fluid line having a proximal end fluidly connectable to a source of a first fluid and a second fluid line having a proximal end fluidly connectable to a source of a second fluid. A flow mixing device is in fluid communication with distal ends of the first and second fluid lines. The flow mixing device includes a housing, a first fluid port provided for receiving the first fluid, and a second fluid port for receiving the second fluid. A mixing chamber is disposed within the housing and is in fluid communication with the first and second fluid ports. A third fluid port in fluid communication with the mixing chamber for discharging a mixed solution of the first and second fluids. A turbulent flow inducing member is disposed within the mixing chamber for promoting turbulent mixing of the first and second fluids.

5. 发明授权

US11291766B2 System and method for fluid engagement with a pressure jacket and syringe cap 有权
公开(公告)号：US11291766B2
公开(公告)日：2022-04-05
申请号：US15769550
申请日：2016-10-28
申请人： BAYER HEALTHCARE LLC
发明人： Michael J. Swantner , Richard A. Seman , Barry L. Tucker , Arthur E. Uber, III , Kevin P. Cowan , James A. Dedig , Christopher D. Capone
IPC分类号： A61M5/145 , A61M5/315
摘要： A pressure jacket for use with a fluid injector may have a pressure jacket body having a proximal end, a distal end, and a circumferential sidewall extending between the proximal end and the distal end along a pressure jacket longitudinal axis. The pressure jacket may further have at least one resiliently deflectable retaining member having a first segment attached to the pressure jacket body and a second segment protruding from the first segment toward the distal end of the pressure jacket body and deflectable relative to the first segment. The pressure jacket may further have at least one actuation member associated with the at least one resiliently deflectable retaining member. The at least one actuation member may interact with a housing of the fluid injector when the pressure jacket is connected to the housing to deflect the at least one resiliently deflectable retaining member upon rotation of the pressure jacket.

6. 发明授权

US10857345B2 Sterility retaining medical connector assembly and method 有权
公开(公告)号：US10857345B2
公开(公告)日：2020-12-08
申请号：US15974764
申请日：2018-05-09
申请人： BAYER HEALTHCARE LLC
发明人： Arthur E. Uber, III , Kevin Cowan , James A. Dedig , David M. Griffiths , Edward J. Rhinehart , Benjamin Taggart , Mark Trocki
IPC分类号： A61M39/16 , A61M39/10 , A61M39/18 , A61M39/20 , F16L25/00 , A61M39/26
摘要： A medical connector assembly for establishing a fluid connection between a first medical device and a second medical device includes a multi-use connector and a plurality of single-use connectors connected in series. The multi-use connector has a proximal end opposite a distal end along a longitudinal length thereof. The plurality of single-use connectors each have a proximal end opposite a distal end along a longitudinal length thereof. The distal end of the multi-use connector is releasably connected to the proximal end of a first of the serially-connected single-use connectors. When a second of the serially-connected single-use connectors is disconnected from the first single-use connector, the first single-use connector remains connected to the multi-use medical connector as a sterility retaining cover.

7. 发明授权

US10512721B2 System and method for syringe plunger engagement with an injector 有权
公开(公告)号：US10512721B2
公开(公告)日：2019-12-24
申请号：US15334644
申请日：2016-10-26
申请人： BAYER HEALTHCARE LLC
发明人： Michael J. Swantner , Richard A. Seman , Barry L. Tucker , Arthur E. Uber, III , Kevin P. Cowan , James A. Dedig , Christopher D. Capone , Jaroslaw Wlodarczyk
IPC分类号： A61M5/145 , A61M5/315
摘要： A plunger for use with a syringe has a plunger body with a proximal end, a distal end, and a circumferential sidewall extending between the proximal end and the distal end along a plunger longitudinal axis. The plunger further has at least one resiliently deflectable retaining member having a first segment attached to the plunger body and a second segment protruding toward the distal end of the plunger body and deflectable relative to the first segment. The plunger further has at least one actuation member associated with the at least one resiliently deflectable retaining member. The at least one actuation member interacts with a piston to deflect the at least one resiliently deflectable retaining member upon rotation of the plunger relative to the piston. The plunger is engagable with the piston regardless of a rotational orientation of the piston relative to the plunger.

8. 发明授权

US11278853B2 Method for controlling fluid accuracy and backflow compensation 有权
公开(公告)号：US11278853B2
公开(公告)日：2022-03-22
申请号：US16013050
申请日：2018-06-20
申请人： BAYER HEALTHCARE LLC
发明人： Ralph H. Schriver , Andreas Maihoefer , James A. Dedig , Michael A. Spohn , Herbert M. Grubic , Michael J. Swantner , Adam Caruso
IPC分类号： G01F11/02 , B01F5/06 , A61M5/00 , A61M5/168 , A61M39/10 , B01F5/02 , B01F7/00 , B01F13/00 , B01F3/08 , B01F5/00 , B01F15/00 , A61M39/00
摘要： A method for controlling fluid ratio accuracy during a dual flow injection with a powered injection system is described. The method includes predicting a first capacitance volume of a first syringe comprising a first medical fluid and a second capacitance volume of a second syringe comprising a second medical fluid with a first capacitance correction factor and a second capacitance correction factor, respectively, selecting a ratio of the first medical fluid and the second medical fluid to be administered to a patient in the dual flow injection, determining a relative acceleration ratio of a first piston of the first syringe and a second piston of a second syringe based on the predicted first capacitance volume and the predicted second capacitance volume, wherein the relative acceleration ratio is selected to maintain the selected ratio of the first medical fluid and the second medical fluid during the dual flow injection, and injecting a mixture of a first medical fluid and a second medical fluid having the selected ratio with the powered injection system.

9. 发明授权

US10589018B2 Multi-dose disposable system 有权
公开(公告)号：US10589018B2
公开(公告)日：2020-03-17
申请号：US15119467
申请日：2015-02-18
申请人： Bayer HealthCare LLC
发明人： Arthur E. Uber, III , Ralph H. Schriver , Barry L. Tucker , James A. Dedig
IPC分类号： A61M5/00 , A61M5/14 , A61M5/142 , A61M5/145 , A61M39/22 , A61M39/24 , A61M39/26 , A61M39/00
摘要： A multi-dose disposable fluid delivery system includes at least one fluid container, a multi-use fluid path set, and a plurality of single-use fluid path sets. The at least one fluid container has a connection port configured for fluidly connecting with a first end of the multi-use fluid path set. The second end of the multi-fluid path set is configured for fluidly connecting to a fluid injection apparatus. The plurality of single-use fluid path sets is connected in sequence to define a fluid path extending from a first single-use fluid path set to a last single- use fluid path set. Each of the plurality single-use fluid path sets has a first end and a second end. The first end of the first single-use fluid path set is configured for connecting to a delivery line. The second end of the last single-use fluid path set is configured for connecting to the injection apparatus.

10. 发明授权

US10124110B2 Magnetic pressure jacket for fluid injector 有权
公开(公告)号：US10124110B2
公开(公告)日：2018-11-13
申请号：US15028784
申请日：2014-10-17
申请人： BAYER HEALTHCARE LLC
发明人： James A. Dedig , Ralph H. Schriver , Patrick B. Campbell , Herbert M. Grubic
IPC分类号： A61M37/00 , A61M5/00 , A61M5/145 , A61M5/20
摘要： A fluid injector for use with at least one syringe has at least one injector head with a front end configured to releasably receive the at least one syringe. The fluid injector further includes at least one pressure jacket releasably associated with the front end of the at least one injector head for securing the at least one syringe during an injection procedure. A connection mechanism releasably connects the at least one pressure jacket to the front end of the at least one injector head. The connection mechanism includes at least one magnet. The at least one injector head has the at least one magnet while the at least one pressure jacket has a ferromagnetic material configured for magnetically interacting with the at least one magnet.

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