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1. 发明授权

US10441716B2 Fluid mixing control device for a multi-fluid delivery system 有权
公开(公告)号：US10441716B2
公开(公告)日：2019-10-15
申请号：US15864448
申请日：2018-01-08
申请人： BAYER HEALTHCARE LLC
发明人： Ralph H. Schriver , Thomas P. Joyce , Michael Riley , William D. Barlow
IPC分类号： A61M5/168 , G05D11/00 , G05D11/02 , A61M5/14 , G05D7/06 , A61M5/00 , A61M5/315 , A61B6/00 , A61M5/178
摘要： The control device is used to control delivery of fluids from a multi-fluid delivery system during a medical injection procedure. The fluid delivery system includes an injector used to deliver injection fluids to a patient. The control device is operatively associated with the injector for controlling discrete flow rates of injection fluids delivered to the patient. The control device includes first and second actuators associated with the manual control device, and an electronic substrate disposed within the manual control device and having a conductive pattern. The first actuator is operatively associated with the conductive pattern. The conductive pattern includes a plurality of predetermined digital values corresponding to discrete flow rates of injection fluids to be delivered by the injector. The second actuator is operatively associated with the electronic substrate and initiates output signals to the injector corresponding to desired mixture ratios of the injection fluids to be delivered by the injector.

2. 发明授权

US10751465B2 Multi-fluid medical injector system and methods of operation 有权
公开(公告)号：US10751465B2
公开(公告)日：2020-08-25
申请号：US15299913
申请日：2016-10-21
申请人： BAYER HEALTHCARE LLC
发明人： Michael A. Riley , Ralph H. Schriver , William D. Barlow , Thomas P. Joyce , Andreas Maihoefer
IPC分类号： A61M1/00 , A61M31/00 , A61M37/00 , A61B6/00 , A61M5/14 , A61M5/00 , A61M5/145 , A61M5/168 , A61M5/178 , A61M5/142
摘要： A multi-fluid injector system and methods of operation thereof are presented. One embodiment of such a fluid injector system includes an automatic refill procedure for a fluid injector system comprising a fluid injector and an operably engaged syringe. The procedure includes the step of determining, using an electronic control device operably controlling the fluid injector system, whether a fluid injection procedure involving the syringe is impending. If the electronic control device determines that the fluid injection procedure is not impending, such that the automatic refill will not interfere with the fluid injection procedure, an automatic refill of the syringe is initiated.

3. 发明授权

US10029220B2 Fluid path set with turbulent mixing chamber, back flow compensator 有权
公开(公告)号：US10029220B2
公开(公告)日：2018-07-24
申请号：US15417945
申请日：2017-01-27
申请人： BAYER HEALTHCARE LLC
发明人： Ralph H. Schriver , Andreas Maihoefer , James A. Dedig , Michael A. Spohn , Herbert M. Grubic , Michael J. Swantner , Adam Caruso
IPC分类号： B01F5/06 , B01F15/00 , B01F3/08 , A61M5/00 , A61M5/168 , A61M39/10 , B01F5/00 , A61M39/00
摘要： A fluid path set includes a first fluid line having a proximal end fluidly connectable to a source of a first fluid and a second fluid line having a proximal end fluidly connectable to a source of a second fluid. A flow mixing device is in fluid communication with distal ends of the first and second fluid lines. The flow mixing device includes a housing, a first fluid port provided for receiving the first fluid, and a second fluid port for receiving the second fluid. A mixing chamber is disposed within the housing and is in fluid communication with the first and second fluid ports. A third fluid port in fluid communication with the mixing chamber for discharging a mixed solution of the first and second fluids. A turbulent flow inducing member is disposed within the mixing chamber for promoting turbulent mixing of the first and second fluids.

4. 发明授权

US11278853B2 Method for controlling fluid accuracy and backflow compensation 有权
公开(公告)号：US11278853B2
公开(公告)日：2022-03-22
申请号：US16013050
申请日：2018-06-20
申请人： BAYER HEALTHCARE LLC
发明人： Ralph H. Schriver , Andreas Maihoefer , James A. Dedig , Michael A. Spohn , Herbert M. Grubic , Michael J. Swantner , Adam Caruso
IPC分类号： G01F11/02 , B01F5/06 , A61M5/00 , A61M5/168 , A61M39/10 , B01F5/02 , B01F7/00 , B01F13/00 , B01F3/08 , B01F5/00 , B01F15/00 , A61M39/00
摘要： A method for controlling fluid ratio accuracy during a dual flow injection with a powered injection system is described. The method includes predicting a first capacitance volume of a first syringe comprising a first medical fluid and a second capacitance volume of a second syringe comprising a second medical fluid with a first capacitance correction factor and a second capacitance correction factor, respectively, selecting a ratio of the first medical fluid and the second medical fluid to be administered to a patient in the dual flow injection, determining a relative acceleration ratio of a first piston of the first syringe and a second piston of a second syringe based on the predicted first capacitance volume and the predicted second capacitance volume, wherein the relative acceleration ratio is selected to maintain the selected ratio of the first medical fluid and the second medical fluid during the dual flow injection, and injecting a mixture of a first medical fluid and a second medical fluid having the selected ratio with the powered injection system.

5. 发明授权

US10589018B2 Multi-dose disposable system 有权
公开(公告)号：US10589018B2
公开(公告)日：2020-03-17
申请号：US15119467
申请日：2015-02-18
申请人： Bayer HealthCare LLC
发明人： Arthur E. Uber, III , Ralph H. Schriver , Barry L. Tucker , James A. Dedig
IPC分类号： A61M5/00 , A61M5/14 , A61M5/142 , A61M5/145 , A61M39/22 , A61M39/24 , A61M39/26 , A61M39/00
摘要： A multi-dose disposable fluid delivery system includes at least one fluid container, a multi-use fluid path set, and a plurality of single-use fluid path sets. The at least one fluid container has a connection port configured for fluidly connecting with a first end of the multi-use fluid path set. The second end of the multi-fluid path set is configured for fluidly connecting to a fluid injection apparatus. The plurality of single-use fluid path sets is connected in sequence to define a fluid path extending from a first single-use fluid path set to a last single- use fluid path set. Each of the plurality single-use fluid path sets has a first end and a second end. The first end of the first single-use fluid path set is configured for connecting to a delivery line. The second end of the last single-use fluid path set is configured for connecting to the injection apparatus.

6. 发明授权

US10124110B2 Magnetic pressure jacket for fluid injector 有权
公开(公告)号：US10124110B2
公开(公告)日：2018-11-13
申请号：US15028784
申请日：2014-10-17
申请人： BAYER HEALTHCARE LLC
发明人： James A. Dedig , Ralph H. Schriver , Patrick B. Campbell , Herbert M. Grubic
IPC分类号： A61M37/00 , A61M5/00 , A61M5/145 , A61M5/20
摘要： A fluid injector for use with at least one syringe has at least one injector head with a front end configured to releasably receive the at least one syringe. The fluid injector further includes at least one pressure jacket releasably associated with the front end of the at least one injector head for securing the at least one syringe during an injection procedure. A connection mechanism releasably connects the at least one pressure jacket to the front end of the at least one injector head. The connection mechanism includes at least one magnet. The at least one injector head has the at least one magnet while the at least one pressure jacket has a ferromagnetic material configured for magnetically interacting with the at least one magnet.

7. 发明申请

US20170049955A1 Multi-Dose Disposable System 审中-公开
标题翻译：多剂量一次性系统
公开(公告)号：US20170049955A1
公开(公告)日：2017-02-23
申请号：US15119467
申请日：2015-02-18
申请人： BAYER HEALTHCARE LLC
发明人： Arthur E. Uber, III , Ralph H. Schriver , Barry L. Tucker , James A. Dedig
IPC分类号： A61M5/00 , A61M39/24 , A61M5/145 , A61M39/22 , A61M5/14 , A61M5/142
摘要： A multi-dose disposable fluid delivery system includes at least one fluid container, a multi-use fluid path set, and a plurality of single-use fluid path sets. The at least one fluid container has a connection port configured for fluidly connecting with a first end of the multi-use fluid path set. The second end of the multi-fluid path set is configured for fluidly connecting to a fluid injection apparatus. The plurality of single-use fluid path sets is connected in sequence to define a fluid path extending from a first single-use fluid path set to a last single- use fluid path set. Each of the plurality single-use fluid path sets has a first end and a second end. The first end of the first single-use fluid path set is configured for connecting to a delivery line. The second end of the last single-use fluid path set is configured for connecting to the injection apparatus.
摘要翻译：多剂量一次性流体输送系统包括至少一个流体容器，多用途流体路径组和多个一次性流体路径组。所述至少一个流体容器具有被配置为与所述多用途流体路径组的第一端流体连接的连接端口。多流体路径组的第二端构造成流体地连接到流体注射装置。多个一次性流体路径组依次连接以限定从第一单次使用流体路径组延伸到最后一次使用的流体路径组的流体路径。多个一次性流体路径组中的每一个具有第一端和第二端。第一单次使用流体路径组的第一端被配置为连接到输送管线。最后一次使用的流体路径组的第二端构造成用于连接到注射装置。

8. 发明申请

US20160296692A1 System and Method for Medical Fluid Identification and Verification 审中-公开
标题翻译：医学流体识别与验证系统与方法
公开(公告)号：US20160296692A1
公开(公告)日：2016-10-13
申请号：US15038493
申请日：2014-11-25
申请人： BAYER HEALTHCARE LLC
发明人： Jacob Agris, III , Arthur E. Uber, III , Ralph H. Schriver , Evelina Zapatka , Michael A. Spohn
IPC分类号： A61M5/00 , A61M5/172
CPC分类号： A61M5/007 , A61M5/1723 , A61M2005/1403 , A61M2205/3306 , A61M2205/3334 , A61M2205/60 , A61M2205/6063
摘要： A system for injecting fluid to a patient is provided. The system provides manual or automatic verification and identification of the fluid to be injected, prior to, during or after injection. The system includes: a fluid having at least one active compound and at least one tracer compound; an injector configured to deliver the fluid to the patient through a fluid path set; at least one sensor coupled to at least one of the syringe, the injector, or the patient, configured to measure at least one property of the tracer in the fluid, and a feedback path to adjust at least one injection parameter of the injector based on at least one measurement from the at least one sensor.
摘要翻译：提供了一种用于向患者注射流体的系统。该系统在注射之前，期间或之后提供手动或自动验证和识别待注射的流体。该系统包括：具有至少一种活性化合物和至少一种示踪剂化合物的流体; 注射器，其构造成通过流体路径组将流体输送到患者; 耦合到所述注射器，所述注射器或所述患者中的至少一个的至少一个传感器被配置成测量所述流体中的所述示踪剂的至少一个性质，以及反馈路径，用于基于所述至少一个注射参数来调节所述注射器的至少一个注射参数来自所述至少一个传感器的至少一个测量。

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