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1. 发明授权

US09029138B2 Method and device for fixing/stabilising a sample 有权
标题翻译：用于固定/稳定样品的方法和装置
公开(公告)号：US09029138B2
公开(公告)日：2015-05-12
申请号：US12671369
申请日：2008-08-01
申请人： Daniel Groelz , Christian Lenz , Vera Hollaender , Thomas Rothmann
发明人： Daniel Groelz , Christian Lenz , Vera Hollaender , Thomas Rothmann
IPC分类号： C12N5/071 , G01N1/30 , G01N1/36 , B01L3/00
CPC分类号： G01N1/30 , B01L3/508 , G01N1/36
摘要： The present invention provides a method for fixing and/or stabilizing a sample, in which the sample is put into a permeable container, the permeable container having an opening, which is pressed into the sample, then a portion of the sample brought into the permeable container in this way is separated from the rest of the sample, and the container filled with the sample in this way is immersed in fixing and/or stabilizing agents and the sample is fixed and/or stabilized.
摘要翻译：本发明提供了一种用于固定和/或稳定样品的方法，其中将样品放入可渗透容器中，该可渗透容器具有一个开口，该孔被压入样品中，然后一部分样品进入可渗透的以这种方式将容器与样品的其余部分分离，并且以这种方式填充样品的容器浸入固定和/或稳定剂中，并且样品是固定和/或稳定的。

2. 发明授权

US07888006B2 Method for isolating DNA from biological samples 有权
标题翻译：从生物样品中分离DNA的方法
公开(公告)号：US07888006B2
公开(公告)日：2011-02-15
申请号：US10490810
申请日：2002-09-26
申请人： Christian Lenz
发明人： Christian Lenz
IPC分类号： C12Q1/68 , C07H21/02 , C07H21/04
CPC分类号： C12N1/06 , C12N15/1003 , C12Q1/6806
摘要： The present invention relates to an improved process for isolating DNA from biological samples, particularly from human whole blood.
摘要翻译：本发明涉及一种从生物样品中分离DNA，特别是人全血的改进方法。

3. 发明申请

US20100173295A1 FIXATION OF A BIOLOGICAL MATERIAL 审中-公开
标题翻译：生物材料的固定
公开(公告)号：US20100173295A1
公开(公告)日：2010-07-08
申请号：US12528719
申请日：2008-02-27
申请人： Christian Lenz , Daniel Grölz , Uwe Oelmüller
发明人： Christian Lenz , Daniel Grölz , Uwe Oelmüller
IPC分类号： C12Q1/68 , G01N1/30 , G01N1/28
CPC分类号： G01N1/30 , G01N2001/305
摘要： The present invention relates to a method for the treatment of a biological material, comprising the steps i) providing a biological material, and ii) contacting the biological material with a first non-aqueous composition comprising: (a1) 10 to 90 vol. % methanol, and (a2) at least one additional additive, and (a3) optionally an acid. iii) transferring the biological material into a second composition (B) comprising up to 99 vol. % ethanol as well as to a new composition for preservation of a biological material usable in said method and the biological material resulting from this method, a method for the analysis of a treated biological material, various kits as well as the use of the composition in such a method.
摘要翻译：本发明涉及生物材料的处理方法，其包括以下步骤：i）提供生物材料，和ii）使所述生物材料与第一非水性组合物接触，所述第一非水性组合物包含：（a1）10至90体积％％甲醇和（a2）至少一种另外的添加剂，和（a3）任选的酸。 iii）将生物材料转移到包含至多99体积％的第二组合物（B）中。％乙醇，以及用于保存可用于所述方法的生物材料的新组合物和由该方法得到的生物材料，用于分析经处理的生物材料的方法，各种试剂盒以及组合物的用途这样一种方法。

4. 发明申请

US20090206039A1 Device and method for the elimination of magnetic particles from a liquid 有权
标题翻译：从液体中消除磁性颗粒的装置和方法
公开(公告)号：US20090206039A1
公开(公告)日：2009-08-20
申请号：US11990520
申请日：2006-08-18
申请人： Thomas Rothmann , Thomas Deutschmann , Christian Lenz , Cordula (Leurs) Homberg
发明人： Thomas Rothmann , Thomas Deutschmann , Christian Lenz , Cordula (Leurs) Homberg
IPC分类号： B03C1/28 , B03C1/03 , B03C1/02
CPC分类号： B03C1/0332 , B03C1/03 , B03C1/288 , B03C2201/18
摘要： Device for the separation of magnetic particles from a liquid, comprising a first vessel (10), a second vessel (20), a connecting surface (11, 21, 30; 200) that runs from the interior of the first vessel (10) to the interior of the second vessel (20), at least one magnet (40) for the provision of a magnetic field, and a guide element (50) by means of which the magnetic field can be guided along one side of the connecting surface (11, 21, 30; 200).
摘要翻译：用于从液体分离磁性颗粒的装置，包括从第一容器（10）的内部延伸的第一容器（10），第二容器（20），连接表面（11,21,30; 200）到达第二容器（20）内部的至少一个用于提供磁场的磁体（40）和引导元件（50），通过该引导元件可以使该磁场沿连接表面的一侧被引导（11,21,30; 200）。

5. 发明授权

US08673241B2 Method and device for fixing/stabilizing a sample 有权
标题翻译：用于固定/稳定样品的方法和装置
公开(公告)号：US08673241B2
公开(公告)日：2014-03-18
申请号：US12671354
申请日：2008-08-01
申请人： Daniel Groelz , Christian Lenz , Vera Hollaender , Thomas Rothmann
发明人： Daniel Groelz , Christian Lenz , Vera Hollaender , Thomas Rothmann
IPC分类号： A61B10/02
CPC分类号： G01N1/30 , B01L3/508 , G01N1/36
摘要： The present invention provides a method for fixing and/or stabilizing a sample, in which the sample is put into a permeable container with a maximum overall height of 10 mm, preferably of 5 mm, and the container filled with the sample is immersed in fixing and/or stabilizing agents and the sample is fixed and/or stabilized.
摘要翻译：本发明提供一种用于固定和/或稳定样品的方法，其中将样品放入具有最大总高度为10mm，优选为5mm的可渗透容器中，并且将填充有样品的容器浸入固定和/或稳定剂，并且样品是固定和/或稳定的。

6. 发明申请

US20130119116A1 METHOD FOR WELDING HALF SHELLS 审中-公开
标题翻译：焊接半球体的方法
公开(公告)号：US20130119116A1
公开(公告)日：2013-05-16
申请号：US13811945
申请日：2011-07-18
申请人： Christian Lenz , Karsten Niepold , Uwe Zander
发明人： Christian Lenz , Karsten Niepold , Uwe Zander
IPC分类号： B23K31/02
CPC分类号： B23K31/02 , B23K9/0282 , B23K26/282 , B23K33/006 , B23K2101/001 , B23K2103/06 , B23K2103/18 , B23K2103/26 , F01D25/24 , F01D25/246 , F05D2230/232
摘要： A method for welding half shells and thus a method for producing large volume components, such as an inner housing for a steam turbine is disclosed. Two half shells are connected to each other forming a tube-like cross section, and are welded by means of a girth weld to two further half shells that are connected to each other.
摘要翻译：公开了一种用于焊接半壳的方法以及用于制造大体积部件的方法，例如用于汽轮机的内壳。两个半壳彼此连接形成管状横截面，并且通过环形焊缝焊接到彼此连接的两个另外的半壳体。

7. 发明申请

US20100267081A1 METHOD AND DEVICE FOR FIXING/STABILISING A SAMPLE 有权
标题翻译：用于固定/稳定样品的方法和装置
公开(公告)号：US20100267081A1
公开(公告)日：2010-10-21
申请号：US12671354
申请日：2008-08-01
申请人： Daniel Groelz , Christian Lenz , Vera Hollaender , Thomas Rothmann
发明人： Daniel Groelz , Christian Lenz , Vera Hollaender , Thomas Rothmann
IPC分类号： G01N1/28 , C12M1/34
CPC分类号： G01N1/30 , B01L3/508 , G01N1/36
摘要： The present invention provides a method for fixing and/or stabilizing a sample, in which the sample is put into a permeable container with a maximum overall height of 10 mm, preferably of 5 mm, and the container filled with the sample is immersed in fixing and/or stabilizing agents and the sample is fixed and/or stabilized.
摘要翻译：本发明提供一种用于固定和/或稳定样品的方法，其中将样品放入具有最大总高度为10mm，优选为5mm的可渗透容器中，并且将填充有样品的容器浸入固定和/或稳定剂，并且样品是固定和/或稳定的。

8. 发明申请

US20100255571A1 METHOD AND DEVICE FOR FIXING/STABILISING A SAMPLE 有权
标题翻译：用于固定/稳定样品的方法和装置
公开(公告)号：US20100255571A1
公开(公告)日：2010-10-07
申请号：US12671369
申请日：2008-08-01
申请人： Daniel Groelz , Christian Lenz , Vera Hollaender , Thomas Rothmann
发明人： Daniel Groelz , Christian Lenz , Vera Hollaender , Thomas Rothmann
IPC分类号： C12N5/071 , C07H21/02 , C07K14/00 , C12M1/00 , C07H21/04 , B01L3/00
CPC分类号： G01N1/30 , B01L3/508 , G01N1/36
摘要： The present invention provides a method for fixing and/or stabilizing a sample, in which the sample is put into a permeable container, the permeable container having an opening, which is pressed into the sample, then a portion of the sample brought into the permeable container in this way is separated from the rest of the sample, and the container filled with the sample in this way is immersed in fixing and/or stabilizing agents and the sample is fixed and/or stabilized.
摘要翻译：本发明提供了一种用于固定和/或稳定样品的方法，其中将样品放入可渗透容器中，该可渗透容器具有一个开口，该孔被压入样品中，然后一部分样品进入可渗透的以这种方式将容器与样品的其余部分分离，并且以这种方式填充样品的容器浸入固定和/或稳定剂中，并且样品被固定和/或稳定。

9. 发明申请

US20080146790A1 Additive, Method, and Article For Dna Collection, Stabilization, and Purification 审中-公开
标题翻译： Dna收集，稳定和纯化的添加剂，方法和文章
公开(公告)号：US20080146790A1
公开(公告)日：2008-06-19
申请号：US11573670
申请日：2005-08-16
申请人： Daniel Grolz , Christian Lenz , Uwe Oelmuller , Manfred Weiler , Timothy A. Stevens
发明人： Daniel Grolz , Christian Lenz , Uwe Oelmuller , Manfred Weiler , Timothy A. Stevens
IPC分类号： C07H1/08 , C12M1/33
CPC分类号： C12N15/1006 , B01L3/5082 , B01L2200/16 , C12N15/1003 , C12Q1/6806 , C12Q2527/137 , C12Q2527/125
摘要： A system for collection, stabilization, and preparing total DNA for direct purification from biological samples is provided.
摘要翻译：提供了一种收集，稳定和制备用于从生物样品直接纯化的总DNA的系统。

10. 发明授权

US08911680B2 Device for collecting and triggered release of a biological sample 有权
标题翻译：用于收集和触发释放生物样品的装置
公开(公告)号：US08911680B2
公开(公告)日：2014-12-16
申请号：US12521390
申请日：2007-12-27
申请人： Thomas Hanselle , Markus Sprenger-Haussels , Christian Lenz , Daniel Groelz , Uwe Oelmueller
发明人： Thomas Hanselle , Markus Sprenger-Haussels , Christian Lenz , Daniel Groelz , Uwe Oelmueller
IPC分类号： G01N33/48 , B01L3/00 , A61B10/00 , C12N15/10 , G01N1/40 , G01N1/02 , G01N35/00
CPC分类号： B01L3/5029 , A61B10/0051 , A61B2010/0074 , B01L3/50825 , B01L2300/042 , B01L2300/046 , C12N15/1003 , G01N1/4022 , G01N2001/028 , G01N2035/00267 , Y10S436/808
摘要： The invention relates to a system for collecting a biological sample comprising a container having at least one open end, a closure fitting on or in said at least one open end, a holding element connected to said closure and a solid matrix on which said biological sample is deposited, and optionally at least one processing agent, wherein said solid matrix is at least partially transferable into a liquid or dissolved state by changing at least one physico-chemical property of the environment of said matrix without disintegration of the biomolecules comprised in said biological sample deposited on said matrix.
摘要翻译：本发明涉及一种用于收集生物样品的系统，该系统包括具有至少一个开口端的容器，位于所述至少一个开放端上或其中的闭合配件，连接到所述封闭件的保持元件和固体基质，所述生物样品并且任选地至少一种处理剂，其中所述固体基质至少部分地可转移到液体或溶解状态，通过改变所述基质的环境的至少一种物理化学性质而不包括在所述生物中的生物分子的分解样品沉积在所述基质上。

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