专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US07723071B2 DNA molecules encoding opioid receptors and methods of use thereof 失效
标题翻译：编码阿片类受体的DNA分子及其使用方法
公开(公告)号：US07723071B2
公开(公告)日：2010-05-25
申请号：US11855971
申请日：2007-09-14
申请人： Christopher J. Evans , Duane E. Keith, Jr. , Robert H. Edwards , Daniel Kaufman
发明人： Christopher J. Evans , Duane E. Keith, Jr. , Robert H. Edwards , Daniel Kaufman
IPC分类号： G01N33/53 , G01N33/567 , C12P21/06 , C12N1/20 , C12N15/00 , C12N5/00 , C12N5/02 , C12N15/74
CPC分类号： C07K14/705
摘要： Recombinant forms of isolated and purified delta opioid receptors and methods to screen for compounds interactive with delta opioid receptors are described.
摘要翻译：描述了重组形式的分离和纯化的δ阿片受体和筛选与δ阿片受体相互作用的化合物的方法。

2. 发明授权

US07282563B2 Opioid receptors and methods of use 失效
标题翻译：阿片类受体及使用方法
公开(公告)号：US07282563B2
公开(公告)日：2007-10-16
申请号：US10290748
申请日：2002-11-07
申请人： Christopher J. Evans , Duane E. Keith, Jr. , Robert H. Edwards , Daniel Kaufman
发明人： Christopher J. Evans , Duane E. Keith, Jr. , Robert H. Edwards , Daniel Kaufman
IPC分类号： C07K1/00 , C07K14/00 , C07K17/00 , G01N33/53 , G01N33/567
CPC分类号： C07K14/705
摘要： Genes encoding opioid receptors (including opioid-like receptor (ORL) proteins) can be retrieved from vertebrate libraries using the murine probe disclosed herein under low-stringency conditions. The DNA sequence shown in FIG. 5 or its complement can be used to obtain the human delta, kappa and mu genes as well as the murine mu gene and human ORL-1. The probe provided encodes the murine delta opioid receptor.
摘要翻译：可以使用本文公开的小鼠探针在低严格条件下从脊椎动物文库中检索编码阿片受体（包括阿片样物质受体（ORL）蛋白）的基因。图中所示的DNA序列。 5或其补体可用于获得人类δ，κ和μ基因以及鼠μ基因和人类ORL-1。提供的探针编码鼠类阿片受体。

3. 发明授权

US06432652B1 Methods of screening modulators of opioid receptor activity 失效
标题翻译：筛选阿片受体活性调节剂的方法
公开(公告)号：US06432652B1
公开(公告)日：2002-08-13
申请号：US08405271
申请日：1995-03-14
申请人： Christopher J. Evans , Duane E. Keith, Jr. , Robert H. Edwards , Daniel Kaufman
发明人： Christopher J. Evans , Duane E. Keith, Jr. , Robert H. Edwards , Daniel Kaufman
IPC分类号： G01N3353
CPC分类号： C07K14/705
摘要： Genes encoding opioid receptors (including opioid-like receptor (ORL) proteins) can be retrieved from vertebrate libraries using the murine probe disclosed herein under low-stringency conditions. The DNA sequence shown in FIG. 5 or its complement can be used to obtain the human delta, kappa and mu genes as well as the murine mu gene and human ORL-1. The probe provided encodes the murine delta opioid receptor.
摘要翻译：可以使用本文公开的小鼠探针在低严格条件下从脊椎动物文库中检索编码阿片受体（包括阿片样物质受体（ORL）蛋白）的基因。图1所示的DNA序列 5或其补体可用于获得人类δ，kappa和mu基因以及鼠mu基因和人类ORL-1。提供的探针编码鼠类阿片受体。

4. 发明授权

US06265563B1 Opioid receptor genes 失效
标题翻译：阿片受体基因
公开(公告)号：US06265563B1
公开(公告)日：2001-07-24
申请号：US08387707
申请日：1995-02-13
申请人： Christopher J. Evans , Duane E. Keith , Robert H. Edwards , Daniel Kaufman
发明人： Christopher J. Evans , Duane E. Keith , Robert H. Edwards , Daniel Kaufman
IPC分类号： C07H2104
CPC分类号： C07K14/705
摘要： Genes encoding opioid receptors can be retrieved from vertebrate libraries using the murine probe disclosed herein under low-stringency conditions. The DNA sequence shown in FIG. 5 or its complement can be used to obtain the human delta, kappa and mu genes as well as the murine mu gene. The probe provided encodes the murine delta opioid receptor.
摘要翻译：可以使用本文公开的小鼠探针在低严格条件下从脊椎动物文库中检索编码阿片受体的基因。图1所示的DNA序列 5或其补体可用于获得人类δ，κ和μ基因以及鼠mu基因。提供的探针编码鼠类阿片受体。

5. 发明申请

US20080219925A1 DELTA OPIOID RECEPTOR PROTEIN 失效
标题翻译： DELTA OPIOID受体蛋白
公开(公告)号：US20080219925A1
公开(公告)日：2008-09-11
申请号：US11855971
申请日：2007-09-14
申请人： Christopher J. EVANS , Duane E. Keith , Robert H. Edwards , Daniel Kaufman
发明人： Christopher J. EVANS , Duane E. Keith , Robert H. Edwards , Daniel Kaufman
IPC分类号： A61K49/00 , C07H21/04 , C12N5/10 , C12P21/00 , A61K39/395 , A61P43/00 , C12N15/09 , C12Q1/02 , C07K14/00 , C07K16/00
CPC分类号： C07K14/705
摘要： Recombinant forms of isolated and purified delta opioid receptors and methods to screen for compounds interactive with delta opioid receptors are described.
摘要翻译：描述了重组形式的分离和纯化的δ阿片受体和筛选与δ阿片受体相互作用的化合物的方法。

6. 发明授权

US09089531B2 GABA agonists in the treatment of disorders associated with metabolic syndrome and GABA combinations in treatment or prophylaxis of type I diabetes 有权
标题翻译： GABA激动剂用于治疗与代谢综合症和GABA组合相关的疾病，用于治疗或预防I型糖尿病
公开(公告)号：US09089531B2
公开(公告)日：2015-07-28
申请号：US13876147
申请日：2011-09-28
申请人： Daniel Kaufman , Jide Tian
发明人： Daniel Kaufman , Jide Tian
IPC分类号： A61K39/00 , A61K31/197 , A61K31/4465 , A61K45/06 , A61K38/20 , A61K39/39
CPC分类号： A61K31/197 , A61K31/4465 , A61K38/2013 , A61K39/0008 , A61K39/39 , A61K45/06 , A61K2300/00
摘要： In certain embodiments methods are provided for the therapeutic or prophylactic amelioration of one or more symptoms or disorders associated with metabolic syndrome. In various embodiments the methods involve administering to a subject in need thereof, a GABA receptor agonist, in an amount sufficient to ameliorate said one or more symptoms. In certain embodiments methods are provided for the prophylaxis or treatment of type I diabetes and related pathologies that involve the use of GABA or GABA agonists in combination with certain other compounds (e.g., one more antigens (e.g., GAD) that have a therapeutic effect in type I diabetes and/or an anti-CD3 antibody, an anti-CD20 antibody, exendin-4, and/or or a pro-insulin therapeutic).
摘要翻译：在某些实施方案中，提供了用于治疗或预防性改善与代谢综合征相关的一种或多种症状或病症的方法。在各种实施方案中，所述方法包括以足以改善所述一种或多种症状的量施用有需要的受试者GABA受体激动剂。在某些实施方案中，提供了用于预防或治疗I型糖尿病和相关病症的方法，其涉及使用GABA或GABA激动剂与某些其它化合物（例如，另外一种具有治疗作用的抗原（例如GAD））组合 I型糖尿病和/或抗CD3抗体，抗CD20抗体，毒蜥外泌肽-4和/或前胰岛素治疗剂）。

7. 发明授权

US08061672B1 Clamping device for securing metal struts to I-beams for interior wall construction 有权
标题翻译：用于将金属支柱固定到用于内墙结构的I型梁的夹紧装置
公开(公告)号：US08061672B1
公开(公告)日：2011-11-22
申请号：US11688211
申请日：2007-03-19
申请人： Daniel Kaufman
发明人： Daniel Kaufman
IPC分类号： A47H1/10
CPC分类号： E04B2/82
摘要： A securing device for securing a wall to an I-beam. The securing device includes two members that coupled to the sides of an I-beam and are secured together so as to couple the securing device to the I-beam. The two members define a surface that is spaced from the bottom surface of the I-beam that can receive fasteners and the thickness of the two member is such that ordinary fasteners can be used to secure a wall component to the two members of the securing device thereby reducing the need to drill, weld or otherwise attach wall members directly to the I-beam.
摘要翻译：用于将壁固定到工字钢的固定装置。固定装置包括耦合到工字梁的侧面并被固定在一起以便将固定装置耦合到工字梁的两个构件。两个构件限定了与能够接收紧固件的工字梁的底表面间隔开的表面，并且两个构件的厚度使得普通的紧固件可用于将壁部件固定到固定装置的两个构件从而减少了将壁构件直接钻入，焊接或以其他方式附接到工字梁的需要。

8. 发明申请

US20170357385A1 SYSTEMS AND METHODS FOR INTERACTIVELY DISPLAYING USER IMAGES 审中-公开
公开(公告)号：US20170357385A1
公开(公告)日：2017-12-14
申请号：US15149614
申请日：2016-05-09
申请人： Daniel Kaufman
发明人： Daniel Kaufman
IPC分类号： G06F3/0482 , G06F3/0481 , G06F3/0484 , G06F17/30 , G06Q10/10
CPC分类号： G06F3/0482 , G06F3/0481 , G06F3/0484 , G06F16/58 , G06F16/637 , G06F16/639 , G06F16/64 , G06Q10/10
摘要： In accordance with the present invention, an interactive user display application is provided. The application displays and refreshes images that are intended to represent users or members of a social network or other web-based service. Using these images, the interactive user display application allows a user of the application to interact with other users or their profiles while viewing their images or while interacting with or consuming media.

9. 发明申请

US20110119584A1 SYSTEMS AND METHODS FOR INTERACTIVELY DISPLAYING USER IMAGES 审中-公开
标题翻译：用于互动显示用户图像的系统和方法
公开(公告)号：US20110119584A1
公开(公告)日：2011-05-19
申请号：US13015050
申请日：2011-01-27
申请人： Daniel Kaufman
发明人： Daniel Kaufman
IPC分类号： G06F3/01
CPC分类号： G06F3/0482 , G06F3/0481 , G06F3/0484 , G06F16/58 , G06F16/637 , G06F16/639 , G06F16/64 , G06Q10/10
摘要： In accordance with the present invention, an interactive user display application is provided. The application displays and refreshes images that are intended to represent users or members of a social network or other web-based service. Using these images, the interactive user display application allows a user of the application to interact with other users or their profiles while viewing their images or while interacting with or consuming media.
摘要翻译：根据本发明，提供了交互式用户显示应用。应用程序显示和刷新旨在表示用户或社交网络或其他基于Web的服务的成员的图像。使用这些图像，交互式用户显示应用程序允许应用程序的用户在查看图像或与媒体进行交互或消费时与其他用户或其配置文件进行交互。

10. 发明申请

US20050202032A1 Use of neglected target tissue antigens in modulation of immune responses 审中-公开
标题翻译：使用被忽视的靶组织抗原调节免疫反应
公开(公告)号：US20050202032A1
公开(公告)日：2005-09-15
申请号：US10754473
申请日：2004-01-09
申请人： Daniel Kaufman , Jide Tian , Angelica Olcott
发明人： Daniel Kaufman , Jide Tian , Angelica Olcott
IPC分类号： A61K45/00 , A61K38/00 , A61K38/095 , A61K38/17 , A61K38/28 , A61K38/43 , A61K39/00 , A61P3/10 , A61P25/00 , A61P27/02 , A61P29/00 , A61P37/02 , A61P43/00 , C07K14/47
CPC分类号： C07K14/4713 , A61K38/1709 , A61K39/0008
摘要： Disclosed are methods for identifying antigens, termed neglected target tissue antigens, that do not become involved as targets of an abnormal immune response (such as allergy or autoimmunity or more generally inflammation); also disclosed are methods of using NTTAs for inducing regulatory responses and thereby abating abnormal inflammatory immune responses.
摘要翻译：公开了用于鉴定被称为被忽视的靶组织抗原的抗原的方法，其不被作为异常免疫应答的靶标（例如过敏或自身免疫或更一般的炎症）参与; 还公开了使用NTTA诱导调节反应并从而减轻异常炎症免疫应答的方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式