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1. 发明申请

US20190336163A1 DEVICES, SYSTEMS, AND METHODS FOR PERCUTANEOUS TRANS-SEPTAL PUNCTURE 审中-公开
公开(公告)号：US20190336163A1
公开(公告)日：2019-11-07
申请号：US16510925
申请日：2019-07-14
申请人： Corvia Medical, Inc.
发明人： Edward I. McNamara , Matthew J. Finch , Stephen J. Forcucci , Carol A. Devellian
IPC分类号： A61B17/34
摘要： The present teachings provide devices for puncturing the atrial septum percutaneously. Specifically, one aspect of the present teachings provides a trans-septal puncturing device comprising one or more of a locating element, a stabilizing element, a puncturing element, a safety element, and optionally a monitoring element, each of which is disposed in a lumen of a sheath. The locating element and the stabilizing element locate a desired puncture site and stabilize the trans-septal puncturing device at or near the site. The puncturing element of the trans-septal puncturing device has a limited puncturing distance due in certain instances to the safety element. The present teachings provide methods of using such device for percutaneously locating a fossa ovalis, stabilizing such device at the fossa ovalis, and piercing tissue across the fossa ovalis.

2. 发明申请

US20160120550A1 DEVICES AND METHODS FOR TREATING PATENT DUCTUS ARTERIOSUS 审中-公开
标题翻译：用于治疗专利性杜氏菌的装置和方法
公开(公告)号：US20160120550A1
公开(公告)日：2016-05-05
申请号：US14931817
申请日：2015-11-03
申请人： CORVIA MEDICAL, INC.
发明人： Edward I. McNamara , Matthew J. Finch , Stephen J. Forcucci , Carol A. Devellian
IPC分类号： A61B17/12
CPC分类号： A61B17/12109 , A61B17/12036 , A61B17/12172 , A61B2017/1205
摘要： The present teachings provide a device to close a ductus arteriosus percutaneously. One aspect of the present teachings provides a device comprising at least one flange portion configured to be positioned against a vascular wall outside one end of a ductus arteriosus, and a body portion configured to be positioned inside the ductus arteriosus. The body portion of the device has a length adjustable in order for the device to fit inside patients with various ductus arteriosus lengths. The at least one flange portion of the device has pivotability in order for at least one flange to deflect from the longitudinal axis of the body portion so that the deployed device can be positioned at a treatment site allowing the discs to sit flat against the vascular tissue to promote closure while avoiding disruption of flow within the pulmonary artery and aorta or applying excess pressure to the surrounding vascular tissue. The body portion of the device could also at least partially block the ductus arteriosus, and thereby reduce or obstruct blood flow through the ductus arteriosus. The device includes a delivery profile and a deployment profile. Another aspect of the present teachings provides methods of using a device of the present teachings.
摘要翻译：本教导提供经皮闭塞动脉导管未闭的装置。本发明的一个方面提供了一种装置，其包括至少一个凸缘部分，该凸缘部分构造成抵靠动脉导管未闭的一端处的血管壁定位，以及构造成位于动脉导管内的主体部分。装置的主体部分具有可调节的长度，以便装置适合于具有各种动脉导管未闭的长度的患者。该装置的至少一个凸缘部分具有可枢转性，以使至少一个凸缘从主体部分的纵向轴线偏转，使得展开的装置可以定位在处理位置，从而允许圆盘平靠在血管组织上以促进闭合，同时避免肺动脉和主动脉内的流动破裂或对周围血管组织施加过量压力。装置的主体部分还可以至少部分地阻塞动脉导管，从而减少或阻碍通过动脉导管的血流。该设备包括传送配置文件和部署配置文件。本教导的另一方面提供使用本教导的装置的方法。

3. 发明申请

US20180256865A1 DEVICES AND METHODS FOR TREATING HEART FAILURE 审中-公开
公开(公告)号：US20180256865A1
公开(公告)日：2018-09-13
申请号：US15905707
申请日：2018-02-26
申请人： Corvia Medical, Inc.
发明人： Matthew J. Finch , Edward I. McNamara
IPC分类号： A61M27/00 , A61F2/24
CPC分类号： A61M27/002 , A61B17/11 , A61B2017/1107 , A61B2017/1139 , A61F2/2478 , A61F2002/249 , A61F2210/0014 , A61F2230/0039 , A61F2230/005 , A61F2230/0065 , A61M2205/0266 , A61M2205/04 , A61M2210/125
摘要： The present teachings provide a device to change the pressure in a chamber of a heart and methods of making and using thereof. One aspect of the present teachings provides a device comprising a frame (for example, a metallic frame) and a scaffold. The frame of the device has a distal flange portion, a shunt portion, and a proximal flange portion. The distal and proximal flange portions can align with the shunt portion and form an elongated first profile. At least one of the distal and proximal flange portions can bend radially away from the shunt portion to form a flange like profile. The scaffold includes one or more than covering layers and encloses parts of the frame or the entire frame. The covering layer provides a barrier between the biological matter and the frame of the device. The scaffold is designed to control and direct tissue growth, for example, by stimulating an irritation response and inducing cell proliferation around the retention flange and/or discouraging cell proliferation inside the shunt portion.

4. 发明授权

US09937036B2 Devices and methods for retrievable intra-atrial implants 有权
公开(公告)号：US09937036B2
公开(公告)日：2018-04-10
申请号：US14986409
申请日：2015-12-31
申请人： CORVIA MEDICAL, INC.
发明人： Hiroatsu Sugimoto , Stephen J. Forcucci , Edward I. McNamara , Matthew J. Finch , Christopher J. Magnin
IPC分类号： A61F2/24 , A61L31/02 , A61B17/00 , A61B17/221 , A61F2/91 , A61F2/915 , A61B18/14 , A61B17/22 , A61B18/00 , A61F2/06 , A61F2/95
CPC分类号： A61F2/2412 , A61B17/0057 , A61B17/221 , A61B18/1492 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00623 , A61B2017/22035 , A61B2017/2215 , A61B2018/00023 , A61B2018/00351 , A61B2018/144 , A61F2/2418 , A61F2/2427 , A61F2/2436 , A61F2/2493 , A61F2/91 , A61F2/915 , A61F2002/061 , A61F2002/9522 , A61F2210/0076 , A61F2220/0008 , A61F2220/0041 , A61F2220/005 , A61F2220/0058 , A61F2220/0066 , A61F2230/0017 , A61F2230/0019 , A61F2230/005 , A61F2230/0054 , A61F2230/0058 , A61F2230/006 , A61F2230/0067 , A61F2230/0078 , A61F2250/0036 , A61F2250/0098 , A61L31/022
摘要： Devices and methods to enhance the implantation, retrievability, or repositionability are provided. Embodiments of devices include pivotable sections providing the ability to maintain the device's engagement with a delivery system during implantation where the deliver system approaches an opening of the septum at an angle. Embodiments of devices also include configurations that allow for improved retrieval into a delivery system in the event that a malfunction or a problem with the patients physiology is detected.

5. 发明授权

US11589854B2 Apparatus and methods to create and maintain an intra-atrial pressure relief opening 有权
公开(公告)号：US11589854B2
公开(公告)日：2023-02-28
申请号：US16417576
申请日：2019-05-20
申请人： Corvia Medical, Inc.
发明人： David S. Celermajer , Edward I. McNamara , Michael W. Sutherland , Hiroatsu Sugimoto
IPC分类号： A61B18/14 , A61B17/32 , A61M25/00 , A61M25/06 , A61B17/3205 , A61B17/34 , A61B17/00 , A61B17/02 , A61F2/06 , A61F2/24 , A61M27/00 , A61M25/10 , A61M29/02 , A61B18/00 , A61N7/02 , A61B6/12 , A61B6/00 , A61B8/08 , A61B17/22 , A61B18/04 , A61B18/24 , A61M25/09
摘要： The present disclosure relates to a method and a device for treating heart failure by normalizing elevated blood pressure in the left and right atria of a heart of a mammal. The present disclosure includes methods for creating and maintaining an opening in the atrial septum. Tools for making an opening and enlarging the opening are also disclosed. Use of the techniques and tools described herein prolongs the patency of an intra-atrial pressure relief opening.

6. 发明授权

US10932786B2 Devices and methods for treating patent ductus arteriosus 有权
公开(公告)号：US10932786B2
公开(公告)日：2021-03-02
申请号：US14931817
申请日：2015-11-03
申请人： Corvia Medical, Inc.
发明人： Edward I. McNamara , Matthew J. Finch , Stephen J. Forcucci , Carol A. Devellian
IPC分类号： A61B17/12
摘要： The present teachings provide a device to close a ductus arteriosus percutaneously. One aspect of the present teachings provides a device comprising at least one flange portion configured to be positioned against a vascular wall outside one end of a ductus arteriosus, and a body portion configured to be positioned inside the ductus arteriosus. The body portion of the device has a length adjustable in order for the device to fit inside patients with various ductus arteriosus lengths. The at least one flange portion of the device has pivotability in order for at least one flange to deflect from the longitudinal axis of the body portion so that the deployed device can be positioned at a treatment site allowing the discs to sit flat against the vascular tissue to promote closure while avoiding disruption of flow within the pulmonary artery and aorta or applying excess pressure to the surrounding vascular tissue. The body portion of the device could also at least partially block the ductus arteriosus, and thereby reduce or obstruct blood flow through the ductus arteriosus. The device includes a delivery profile and a deployment profile. Another aspect of the present teachings provides methods of using a device of the present teachings.

7. 发明授权

US09757107B2 Methods and devices for intra-atrial shunts having adjustable sizes 有权
公开(公告)号：US09757107B2
公开(公告)日：2017-09-12
申请号：US14612022
申请日：2015-02-02
申请人： CORVIA MEDICAL, INC.
发明人： Edward I. McNamara , Michael W. Sutherland , Matthew J. Finch , Stephen J. Forcucci , John Mitzel , David S. Celermajer , Hiroatsu Sugimoto
IPC分类号： A61B17/00 , A61F2/91 , A61F2/915 , A61F2/07
CPC分类号： A61B17/0057 , A61B2017/00247 , A61B2017/00575 , A61B2017/00584 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623 , A61F2/91 , A61F2/915 , A61F2002/075
摘要： Devices and methods for treating heart disease by normalizing elevated blood pressure in the left and right atria of a heart of a mammal are disclosed. Devices may include an adjustable hydraulic diameter shunt portion which can be manually adjusted in vivo. Methods are provided for adjusting the flow rate of the devices in vivo.

8. 发明授权

US11135410B2 Devices and methods for treating heart failure 有权
公开(公告)号：US11135410B2
公开(公告)日：2021-10-05
申请号：US15905707
申请日：2018-02-26
申请人： Corvia Medical, Inc.
发明人： Matthew J. Finch , Edward I. McNamara
IPC分类号： A61M27/00 , A61F2/24 , A61B17/11
摘要： The present teachings provide a device to change the pressure in a chamber of a heart and methods of making and using thereof. One aspect of the present teachings provides a device comprising a frame (for example, a metallic frame) and a scaffold. The frame of the device has a distal flange portion, a shunt portion, and a proximal flange portion. The distal and proximal flange portions can align with the shunt portion and form an elongated first profile. At least one of the distal and proximal flange portions can bend radially away from the shunt portion to form a flange like profile. The scaffold includes one or more than covering layers and encloses parts of the frame or the entire frame. The covering layer provides a barrier between the biological matter and the frame of the device. The scaffold is designed to control and direct tissue growth, for example, by stimulating an irritation response and inducing cell proliferation around the retention flange and/or discouraging cell proliferation inside the shunt portion.

9. 发明授权

US10376680B2 Methods, systems, and devices for resizable intra-atrial shunts 有权
公开(公告)号：US10376680B2
公开(公告)日：2019-08-13
申请号：US14878710
申请日：2015-10-08
申请人： CORVIA MEDICAL, INC.
发明人： Edward I. McNamara , Michael W. Sutherland , Matthew J. Finch , Stephen J. Forcucci
IPC分类号： A61M27/00 , A61F2/24 , A61B17/00
摘要： Devices and methods for treating heart disease by normalizing elevated blood pressure in the left and right atria of a heart of a mammal are disclosed. Devices may include an adjustable hydraulic diameter and/or a removable and/or replaceable shunt portion. Devices may include absorbable materials, the absorption of which directly or indirectly causes alterations of the fluid flow capacities the devices.

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