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1. 发明授权

US08193507B2 System and method for compensating for anode gain non-uniformity in multi-anode position sensitive photomultiplier tube 有权
标题翻译：用于补偿多阳极位置敏感光电倍增管中阳极增益不均匀的系统和方法
公开(公告)号：US08193507B2
公开(公告)日：2012-06-05
申请号：US12791988
申请日：2010-06-02
申请人： Jae Sung Lee , Chan Mi Lee , Sun Il Kwon , Mikiko Ito , Hyun Suk Yoon , Sang Keun Park , Seong Jong Hong , Dong Soo Lee
发明人： Jae Sung Lee , Chan Mi Lee , Sun Il Kwon , Mikiko Ito , Hyun Suk Yoon , Sang Keun Park , Seong Jong Hong , Dong Soo Lee
IPC分类号： G01T1/208
CPC分类号： G01T1/248 , G01T1/2018
摘要： The present invention relates to a system and method for compensating for anode gain non-uniformity in a Multi-anode Position Sensitive Photomultiplier Tube (PS-PMT), in which a compensation unit is disposed between the multi-anode position sensitive photomultiplier tube and a position detection circuit unit and configured to uniform a current signal inputted to the position detection circuit unit, thereby compensating for anode gain non-uniformity. In accordance with the present invention, the compensation unit for changing resistance is used. Accordingly, there is an advantage in that the gain non-uniformity of each of the anodes of the PS-PMT can be compensated for. Furthermore, the gain non-uniformity of each of the anodes of the PS-PMT is compensated for by changing resistance values of the variable resistances of the compensation unit. Accordingly, there is an advantage in that the interaction positions of gamma rays can be calculated more precisely.
摘要翻译：本发明涉及一种用于补偿多阳极位置敏感光电倍增管（PS-PMT）中的阳极增益不均匀性的系统和方法，其中补偿单元设置在多阳极位置敏感光电倍增管和位置检测电路单元，并且被配置为使输入到位置检测电路单元的电流信号均匀，从而补偿阳极增益不均匀。根据本发明，使用用于改变电阻的补偿单元。因此，可以补偿PS-PMT的每个阳极的增益不均匀性的优点。此外，通过改变补偿单元的可变电阻的电阻值来补偿PS-PMT的每个阳极的增益不均匀性。因此，可以更精确地计算γ射线的相互作用位置的优点。

2. 发明申请

US20110192980A1 SYSTEM AND METHOD FOR COMPENSATING FOR ANODE GAIN NON-UNIFORMITY IN MULTI-ANODE POSITION SENSITIVE PHOTOMULTIPLIER TUBE 有权
标题翻译：用于补偿多阳性位置敏感光电管中ANODE GAIN非均匀性的系统和方法
公开(公告)号：US20110192980A1
公开(公告)日：2011-08-11
申请号：US12791988
申请日：2010-06-02
申请人： Jae Sung Lee , Chan Mi Lee , Sun Il Kwon , Mikiko Ito , Hyun Suk Yoon , Sang Keun Park , Seong Jong Hong , Dong Soo Lee
发明人： Jae Sung Lee , Chan Mi Lee , Sun Il Kwon , Mikiko Ito , Hyun Suk Yoon , Sang Keun Park , Seong Jong Hong , Dong Soo Lee
IPC分类号： G01T1/208
CPC分类号： G01T1/248 , G01T1/2018
摘要： The present invention relates to a system and method for compensating for anode gain non-uniformity in a Multi-anode Position Sensitive Photomultiplier Tube (PS-PMT), in which a compensation unit is disposed between the multi-anode position sensitive photomultiplier tube and a position detection circuit unit and configured to uniform a current signal inputted to the position detection circuit unit, thereby compensating for anode gain non-uniformity. In accordance with the present invention, the compensation unit for changing resistance is used. Accordingly, there is an advantage in that the gain non-uniformity of each of the anodes of the PS-PMT can be compensated for. Furthermore, the gain non-uniformity of each of the anodes of the PS-PMT is compensated for by changing resistance values of the variable resistances of the compensation unit. Accordingly, there is an advantage in that the interaction positions of gamma rays can be calculated more precisely.
摘要翻译：本发明涉及一种用于补偿多阳极位置敏感光电倍增管（PS-PMT）中的阳极增益不均匀性的系统和方法，其中补偿单元设置在多阳极位置敏感光电倍增管和位置检测电路单元，并且被配置为使输入到位置检测电路单元的电流信号均匀，从而补偿阳极增益不均匀。根据本发明，使用用于改变电阻的补偿单元。因此，可以补偿PS-PMT的每个阳极的增益不均匀性的优点。此外，通过改变补偿单元的可变电阻的电阻值来补偿PS-PMT的每个阳极的增益不均匀性。因此，可以更精确地计算γ射线的相互作用位置的优点。

3. 发明授权

US08476600B2 Apparatus and method for measuring depth-of-interaction using light dispersion and positron emission tomography using the same 有权
标题翻译：使用其使用光分散和正电子发射断层摄影测量相互作用深度的装置和方法
公开(公告)号：US08476600B2
公开(公告)日：2013-07-02
申请号：US12766638
申请日：2010-04-23
申请人： Jae Sung Lee , Mikiko Ito , Seong Jong Hong
发明人： Jae Sung Lee , Mikiko Ito , Seong Jong Hong
IPC分类号： G01T1/20
CPC分类号： G01T1/2002 , A61B6/037 , G01T1/202
摘要： The present invention provides an apparatus for measuring a Depth-Of-Interaction (DOI), comprising a crystal layer 10 of a mono layer in which a plurality of crystals for absorbing gamma rays are consecutively arranged, scintillation light detectors disposed at one end of the crystals and configured to detect scintillation light emitted from the crystal layer 10 by the gamma rays, change means included in the crystals and configured to linearly change transmittance in a length direction of the crystals, and a control unit 30 configured to calculate the DOI in the crystal layer 10 on a basis of the first output signal and the second output signal. The scintillation light detector outputs the first output signal in one direction and the second output signal in a direction at a right angle to the one direction.
摘要翻译：本发明提供了一种用于测量深度相互作用（DOI）的装置，包括其中连续布置多个用于吸收伽马射线的晶体的单层的晶体层10，设置在该层的一端的闪烁光检测器晶体，被配置为通过伽马射线检测从晶体层10发射的闪烁光，包括在晶体中的构造为在晶体的长度方向上线性地改变透射率的改变装置，以及控制单元30，被配置为计算晶体中的DOI 基于第一输出信号和第二输出信号的晶体层10。闪烁光检测器在一个方向上输出第一输出信号，并以与该一个方向成直角的方向输出第二输出信号。

4. 发明申请

US20100270463A1 APPARATUS AND METHOD FOR MEASURING DEPTH-OF-INTERACTION USING LIGHT DISPERSION AND POSITRON EMISSION TOMOGRAPHY USING THE SAME 有权
标题翻译：使用光散射测量深度相互作用的装置和方法，并使用它们的位置发射测量
公开(公告)号：US20100270463A1
公开(公告)日：2010-10-28
申请号：US12766638
申请日：2010-04-23
申请人： Jae Sung Lee , Mikiko Ito , Seong Jong Hong
发明人： Jae Sung Lee , Mikiko Ito , Seong Jong Hong
IPC分类号： G12B13/00 , G01T1/208 , G01T1/166
CPC分类号： G01T1/2002 , A61B6/037 , G01T1/202
摘要： The present invention provides an apparatus for measuring a Depth-Of-Interaction (DOI), comprising a crystal layer 10 of a mono layer in which a plurality of crystals for absorbing gamma rays are consecutively arranged, scintillation light detectors disposed at one end of the crystals and configured to detect scintillation light emitted from the crystal layer 10 by the gamma rays, change means included in the crystals and configured to linearly change transmittance in a length direction of the crystals, and a control unit 30 configured to calculate the DOI in the crystal layer 10 on a basis of the first output signal and the second output signal. The scintillation light detector outputs the first output signal in one direction and the second output signal in a direction at a right angle to the one direction.
摘要翻译：本发明提供了一种用于测量深度相互作用（DOI）的装置，包括其中连续布置多个用于吸收伽马射线的晶体的单层的晶体层10，设置在该层的一端的闪烁光检测器晶体，被配置为通过伽马射线检测从晶体层10发射的闪烁光，包括在晶体中的构造为在晶体的长度方向上线性地改变透射率的改变装置，以及控制单元30，被配置为计算晶体中的DOI 基于第一输出信号和第二输出信号的晶体层10。闪烁光检测器在一个方向上输出第一输出信号，并以与该一个方向成直角的方向输出第二输出信号。

5. 发明申请

US20130119262A1 RADIATION DIAGNOSIS APPARATUS 有权
标题翻译：辐射诊断设备
公开(公告)号：US20130119262A1
公开(公告)日：2013-05-16
申请号：US13468188
申请日：2012-05-10
申请人： Hyun Suk Yoon , Jae Sung Lee
发明人： Hyun Suk Yoon , Jae Sung Lee
IPC分类号： G01T1/16
CPC分类号： G01T1/17
摘要： The radiation diagnosis apparatus includes: a first radiation detector; a second radiation detector for generating an output signal having a same polarity as that of the first radiation detector; an inverter formed at an output terminal of the first radiation detector to invert the polarity of the input output signal; a discriminator for receiving a common signal from the first and second radiation detector and outputting a control signal corresponding to the input common signal; and a data acquisition unit for converting an input signal to a digital signal according to the control signal while taking output signals of the plurality of inverters and the second radiation detector as inputs, and identifying an output signal of which detector of the first and second detectors the input signal is according to a polarity difference of the input signal.
摘要翻译：辐射诊断装置包括：第一辐射检测器; 第二辐射检测器，用于产生具有与第一辐射检测器相同极性的输出信号; 反相器，形成在所述第一辐射检测器的输出端，以反转所述输入输出信号的极性; 鉴别器，用于从第一和第二辐射检测器接收公共信号，并输出对应于输入公共信号的控制信号; 以及数据获取单元，用于根据控制信号将输入信号转换为数字信号，同时以多个反相器和第二辐射检测器的输出信号作为输入，并且识别第一和第二检测器的哪个检测器的输出信号输入信号根据输入信号的极性差。

6. 发明授权

US08729481B2 Radiation diagnosis apparatus 有权
标题翻译：辐射诊断仪
公开(公告)号：US08729481B2
公开(公告)日：2014-05-20
申请号：US13468188
申请日：2012-05-10
申请人： Hyun Suk Yoon , Jae Sung Lee
发明人： Hyun Suk Yoon , Jae Sung Lee
IPC分类号： G01T1/20 , G01T1/24 , G01N23/00
CPC分类号： G01T1/17
摘要： A radiation diagnosis apparatus, which employs a reduced number of data acquisition units while showing the same effect as that of the related art (PET, SPECT or x-ray CT) includes: a first radiation detector; a second radiation detector an inverter formed at an output terminal of the first radiation detector; a discriminator for receiving a common signal from the first and second radiation detector and outputting a control signal corresponding to the input common signal; and a data acquisition unit and indentifying an output signal of which detector of the first and second detectors the input signal is according to a polarity difference of the input signal, to provide a radiation diagnosis apparatus which employs a reduced number of data acquisition units while showing the same effect as that of the related art.
摘要翻译：同时显示与现有技术（PET，SPECT或X射线CT）相同效果的数据采集单元数量减少的放射线诊断装置包括：第一放射线检测器; 第二辐射检测器，形成在所述第一辐射检测器的输出端处的反相器; 鉴别器，用于从第一和第二辐射检测器接收公共信号，并输出对应于输入公共信号的控制信号; 数据采集单元，根据输入信号的极性差来识别第一和第二检测器的检测器的输入信号，以提供采用数量少的数据采集单元的放射诊断装置，同时显示具有与现有技术相同的效果。

7. 发明授权

US09636109B2 Biologically active sutures for regenerative medicine 有权
公开(公告)号：US09636109B2
公开(公告)日：2017-05-02
申请号：US12507635
申请日：2009-07-22
申请人： William L. Murphy , Jae Sung Lee , Mark D. Markel , Ben K. Graf , Geoffrey Baer , Yan Lu
发明人： William L. Murphy , Jae Sung Lee , Mark D. Markel , Ben K. Graf , Geoffrey Baer , Yan Lu
IPC分类号： A61B17/04 , A61B17/06 , A61L27/32 , A61L27/54 , A61L27/58 , A61L29/10 , A61L29/14 , A61L29/16 , A61L31/08 , A61L31/14 , A61L31/16 , A61L17/00 , A61L17/06 , A61L17/14 , A61B17/00
CPC分类号： A61B17/06166 , A61B2017/00889 , A61B2017/00893 , A61L17/005 , A61L17/06 , A61L17/145 , A61L27/32 , A61L27/54 , A61L27/58 , A61L29/106 , A61L29/148 , A61L29/16 , A61L31/086 , A61L31/148 , A61L31/16
摘要： The present disclosure generally relates to biodegradable and bioresorbable materials having a mineral layer on the surface of the material. More particularly, the disclosure relates to biodegradable and bioresorbable orthopedic devices having a degradable mineral layer on the surface thereof that can be used as a delivery vehicle for biological substances. Also provided are various methods of using the mineralized devices in tissue regeneration, including bone tissue engineering, and methods for producing the mineralized devices.

8. 发明授权

US08897110B2 Method and apparatus for recording/reproducing on/from a recording medium 有权
标题翻译：用于记录/再现记录介质的方法和装置
公开(公告)号：US08897110B2
公开(公告)日：2014-11-25
申请号：US12992063
申请日：2009-04-30
申请人： Jae Sung Lee
发明人： Jae Sung Lee
IPC分类号： G11B20/18 , G11B7/0065 , G11B7/007 , G11B7/08
CPC分类号： G11B7/0065 , G11B7/00781 , G11B7/083 , G11B20/18 , G11B2220/2504
摘要： The present invention provides a recording medium reproducing method comprising the steps of: irradiating light onto a recording medium, the recording medium including a data image and a reference pattern, the reference pattern being divided by a plurality of fractional regions, the fractional regions being in invert, rotational and symmetrical relationship; determining information associated to data-image distortion based on the reference pattern; and correcting position of the data image based on the information relating to data-image distortion.
摘要翻译：本发明提供了一种记录介质再现方法，包括以下步骤：将光照射到记录介质上，所述记录介质包括数据图像和参考图形，所述参考图案被多个分数区域划分，所述分数区域在反转，旋转和对称关系; 基于参考图案确定与数据图像失真相关联的信息; 以及基于与数据图像失真有关的信息来校正数据图像的位置。

9. 发明授权

US08420774B2 Decorating hydroxyapatite biomaterials with modular biologically active molecules 有权
标题翻译：用模块化生物活性分子装饰羟基磷灰石生物材料
公开(公告)号：US08420774B2
公开(公告)日：2013-04-16
申请号：US12628666
申请日：2009-12-01
申请人： William L. Murphy , Jae Sung Lee , Mark D. Markel , Ben K. Graf
发明人： William L. Murphy , Jae Sung Lee , Mark D. Markel , Ben K. Graf
IPC分类号： C07K2/00 , C07K14/00 , C07K9/00
CPC分类号： B05D1/18 , B05D1/28 , C07K14/50 , C07K14/51 , C07K14/52
摘要： A modular peptide design strategy wherein the modular peptide has two functional units separated by a spacer portion is disclosed. More particularly, the design strategy combines a hydroxyapatite-binding portion and a biomolecule-derived portion. The modular peptides have improved non-covalent binding to the surface of the HA-based materials, and are capable of initiating osteogenesis, angiogenesis, and/or osteogenic differentiation.
摘要翻译：公开了一种模块化肽设计策略，其中模块化肽具有由间隔物部分分开的两个功能单元。更具体地，设计策略将羟基磷灰石结合部分和衍生生物分子的部分组合。模块化肽具有改善的与HA基材料表面的非共价结合，并且能够启动成骨，血管生成和/或成骨分化。

10. 发明申请

US20120117374A1 CENTRAL MANAGEMENT COMPUTING SYSTEM 审中-公开
标题翻译：中央管理计算系统
公开(公告)号：US20120117374A1
公开(公告)日：2012-05-10
申请号：US13384034
申请日：2009-10-08
申请人： Won Ok Kwon , Jae Sung Lee , Seong Woon Kim
发明人： Won Ok Kwon , Jae Sung Lee , Seong Woon Kim
IPC分类号： G06F1/26
CPC分类号： G06F3/0227 , G06F1/189 , G06F1/26 , H02J1/00
摘要： Provided is a central management computing system. The central management computing system includes a plurality of terminals, and a rack system. The rack system is connected to the plurality of terminals. The rack system includes a rack power supply unit, a plurality of computers, and a switch. The rack power supply unit is mounted in a rack and converts an AC power into a plurality of DC powers to output to a plurality of DC output ports. The plurality of computers are mounted in the rack and receive the DC powers from the DC output ports. The switch is mounted in the rack and dynamically connects the computers to the terminals, respectively.
摘要翻译：提供了一个中央管理计算系统。中央管理计算系统包括多个终端和机架系统。机架系统连接到多个终端。机架系统包括机架电源单元，多个计算机和开关。机架电源单元安装在机架中，并将AC电力转换成多个DC电力，以输出到多个DC输出端口。多个计算机安装在机架中并从DC输出端口接收直流电力。交换机安装在机架中，并分别动态地将计算机连接到终端。

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