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1. 发明申请

US20150367077A1 Drug Delivery Device with Dose Capturing Module 有权
标题翻译：带药量的药物输送装置
公开(公告)号：US20150367077A1
公开(公告)日：2015-12-24
申请号：US14767315
申请日：2014-02-19
申请人： NOVO NORDISK A/S
发明人： Christian Plambech , John Oestergaard Madsen , Jesper Peter Windum
IPC分类号： A61M5/315 , A61M5/50
CPC分类号： A61M5/31528 , A61M5/1452 , A61M5/31533 , A61M5/5086 , A61M2205/33 , A61M2205/52
摘要： A drug delivery system is provided comprising drug expelling means adapted to expel a set dose from a drug-filled cartridge, the expelling means comprising a rotational member adapted to rotate relative to a housing and corresponding to a set and/or expelled dose, the system comprising a sensor adapted to detect a set and/or an expelled dose. The sensor comprises a first portion mounted to and rotating with the rotational member, and a second portion comprising a second rotary sensor part mounted non-rotationally relative to the housing. The first portion comprises electronic circuitry, and a first rotary sensor part, and the second portion comprises a second rotary sensor part mounted non-rotationally relative to the housing. The first and second rotary sensor parts rotate relative to each other during set- ting and/or expelling of a dose of drug.
摘要翻译：提供了药物递送系统，其包括适于从药物填充的药筒排出凝固剂量的药物排出装置，排出装置包括适于相对于壳体旋转并对应于凝固和/或排出剂量的旋转构件，该系统包括适于检测组和/或排出剂量的传感器。传感器包括安装到旋转构件并与旋转构件一起旋转的第一部分，以及包括相对于壳体非旋转地安装的第二旋转传感器部分的第二部分。第一部分包括电子电路和第一旋转传感器部分，并且第二部分包括相对于壳体非旋转地安装的第二旋转传感器部分。第一和第二旋转传感器部件在一定剂量的药物的设定和/或排出期间相对于彼此旋转。

2. 发明授权

US10213559B2 Drug delivery device with brake mechanism 有权
公开(公告)号：US10213559B2
公开(公告)日：2019-02-26
申请号：US15028867
申请日：2014-10-14
申请人： Novo Nordisk A/S
发明人： Morten Soerensen , Bo Kvolsbjerg , Kalle Holck Madsen , Christian Plambech , Jesper Peter Windum
IPC分类号： A61M5/315 , A61M5/24 , A61M5/20 , A61M5/31
摘要： A drug delivery device (1) comprises a housing and an expelling assembly adapted to expel a dose of drug from a cartridge (380). The expelling assembly comprises a drive spring (135) which in an energized state is adapted to drive the expelling assembly, a rotating component (550,650) adapted to rotate relative to an axis of rotation during expelling of a dose of drug, and user actuated release means (191, 190) for releasing the drive spring to thereby expel a dose of drug. The device is provided with a brake element (575, 675) being moveable in a plane generally perpendicular to the axis of rotation, the brake element being adapted to engage the rotating component such that during rotation thereof the brake element is moved back and forth, whereby the brake element provides a braking action on the rotating component.

3. 发明申请

US20180339098A1 A MEDICAL INJECTION DEVICE HAVING A SEALABLE CLEANING RESERVOIR 审中-公开
公开(公告)号：US20180339098A1
公开(公告)日：2018-11-29
申请号：US15757931
申请日：2016-09-19
申请人： Novo Nordisk A/S
发明人： Bjoern Gullak Larsen , Christian Plambech , Lars Eilertsen , Mattias Ingerslev , Ruben Archilla , Soeren Dyring Jensen
IPC分类号： A61M5/00 , A61M5/32 , A61M5/24
摘要： The present invention concerns a medical injection device for apportioning set doses of a preservative containing liquid drug. The injection device comprises a housing supporting a cartridge containing the preservative containing liquid drug and a needle cannula for transferring the liquid drug from the cartridge and through the skin of a user. Further, a needle shield which is axially movable in relation to the housing is also present. The axially movable shield carries a cleaning reservoir for cleaning at least the tip of the needle cannula between subsequent injections and the cleaning reservoir is preferably filled with preservative containing liquid drug directly from the cartridge upon initiation of the injection device. In order to eliminate any overpressure being built up inside the cleaning reservoir during the filling process, the cleaning reservoir is provided with an outlet configured to be permanently sealed by a user activated operation.

4. 发明申请

US20180289895A1 DRUG DELIVERY DEVICE WITH SLIM DRIVE MECHANISM 审中-公开
公开(公告)号：US20180289895A1
公开(公告)日：2018-10-11
申请号：US15766581
申请日：2016-10-07
申请人： Novo Nordisk A/S
发明人： Jesper Peter Windum , Lars Peter Klitmose , Christian Plambech
IPC分类号： A61M5/20 , A61M5/315
摘要： A drug delivery device comprises a housing (201) and an expelling assembly with a piston rod (220), a drive tube (260) with an outer surface and a scale drum (270) arranged between the drive tube and the housing, the scale drum being coupled to the housing and the drive tube outer surface. The device further comprises a drive spring (255) arranged between the housing and the drive tube, and setting means (280) allowing a user to simultaneously set a dose amount to be expelled and strain the drive spring correspondingly by rotation of the drive tube. The scale drum is coupled to the drive tube via a spline connection, wherein the drive spring is arranged proximally of the spline connection when the spline connection is in its proximal-most position.

5. 发明授权

US11458251B2 Drug delivery device with slim drive mechanism 有权
公开(公告)号：US11458251B2
公开(公告)日：2022-10-04
申请号：US15766581
申请日：2016-10-07
申请人： Novo Nordisk A/S
发明人： Christian Plambech , Jesper Peter Windum , Lars Peter Klitmose
IPC分类号： A61M5/20 , A61M5/315 , A61M5/24
摘要： A drug delivery device comprises a housing (201) and an expelling assembly with a piston rod (220), a drive tube (260) with an outer surface and a scale drum (270) arranged between the drive tube and the housing, the scale drum being coupled to the housing and the drive tube outer surface. The device further comprises a drive spring (255) arranged between the housing and the drive tube, and setting means (280) allowing a user to simultaneously set a dose amount to be expelled and strain the drive spring correspondingly by rotation of the drive tube. The scale drum is coupled to the drive tube via a spline connection, wherein the drive spring is arranged proximally of the spline connection when the spline connection is in its proximal-most position.

6. 发明授权

US11164668B2 Pen-type drug delivery device with electronic display on clip member 有权
公开(公告)号：US11164668B2
公开(公告)日：2021-11-02
申请号：US15519031
申请日：2015-10-22
申请人： Novo Nordisk A/S
发明人： Jesper Peter Windum , Christian Plambech , Lars Peter Klitmose , John Oestergaard Madsen
IPC分类号： A61M5/31 , G16H20/17 , A61M5/24 , A61M5/315 , A61M5/20 , A61M5/32
摘要： A portable pen-type drug injection device (300) comprises a main portion (301) and a clip (360). The clip comprises a base portion mounted to a portion of the drug delivery device, and a clip gripping portion with a free end. The device further comprises drug expelling means having dose setting means (340) allowing a user to set a dose of drug to be expelled, and a piston rod adapted to move a piston of a loaded cartridge in a distal direction to thereby expel drug from the cartridge. Electronic circuitry comprises sensor means adapted to detect a set and/or an expelled dose, and a display (374) is provided to display dose-related values, wherein at least a portion of the display is arranged in the flexible clip main portion.

7. 发明授权

US11052185B2 Medical injection device having a sealable cleaning reservoir 有权
公开(公告)号：US11052185B2
公开(公告)日：2021-07-06
申请号：US15757931
申请日：2016-09-19
申请人： Novo Nordisk A/S
发明人： Bjoern Gullak Larsen , Christian Plambech , Lars Eilertsen , Mattias Ingerslev , Ruben Archilla , Soeren Dyring Jensen
IPC分类号： A61M5/00 , A61M5/32 , A61M5/24 , A61M5/20
摘要： The present invention concerns a medical injection device for apportioning set doses of a preservative containing liquid drug. The injection device comprises a housing supporting a cartridge containing the preservative containing liquid drug and a needle cannula for transferring the liquid drug from the cartridge and through the skin of a user. Further, a needle shield which is axially movable in relation to the housing is also present. The axially movable shield carries a cleaning reservoir for cleaning at least the tip of the needle cannula between subsequent injections and the cleaning reservoir is preferably filled with preservative containing liquid drug directly from the cartridge upon initiation of the injection device. In order to eliminate any overpressure being built up inside the cleaning reservoir during the filling process, the cleaning reservoir is provided with an outlet configured to be permanently sealed by a user activated operation.

8. 发明申请

US20170224927A1 Pen-Type Drug Delivery Device with Electronic Display on Clip Member 审中-公开
公开(公告)号：US20170224927A1
公开(公告)日：2017-08-10
申请号：US15519031
申请日：2015-10-22
申请人： Novo Nordisk A/S
发明人： Jesper Peter Windum , Christian Plambech , Lars Peter Klitmose , John Oestergaard Madsen
IPC分类号： A61M5/315 , G06F19/00 , A61M5/32 , A61M5/20 , A61M5/24
CPC分类号： A61M5/31568 , A61M5/20 , A61M5/2033 , A61M5/24 , A61M5/31535 , A61M5/31553 , A61M5/3158 , A61M5/31593 , A61M5/3202 , A61M2005/202 , A61M2005/2407 , A61M2005/3126 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/8206 , A61M2209/084 , G06F19/3468
摘要： A portable pen-type drug injection device (300) comprises a main portion (301) and a clip (360). The clip comprises a base portion mounted to a portion of the drug delivery device, and a clip gripping portion with a free end. The device further comprises drug expelling means having dose setting means (340) allowing a user to set a dose of drug to be expelled, and a piston rod adapted to move a piston of a loaded cartridge in a distal direction to thereby expel drug from the cartridge. Electronic circuitry comprises sensor means adapted to detect a set and/or an expelled dose, and a display (374) is provided to display dose-related values, wherein at least a portion of the display is arranged in the flexible clip main portion.

9. 发明授权

US11197957B2 Drug delivery device with end-of-dose trigger arrangement 有权
公开(公告)号：US11197957B2
公开(公告)日：2021-12-14
申请号：US15738393
申请日：2016-07-05
申请人： Novo Nordisk A/S
发明人： Ebbe Kiilerich , Jesper Peter Windum , Christian Plambech
IPC分类号： A61M5/20 , A61M5/24 , A61M5/315 , A61M5/31
摘要： A drug delivery device comprising a rotatable scale drum, a trigger member, an actuation member, a trigger spring acting on the trigger member and being energized by movement of the actuation member, as well as an end-of-dose switch adapted to be actuated by movement of the trigger member. The trigger member is adapted to be arranged in an axially supported position against the action of the energized trigger spring, and released from the axially supported position when the scale drum is rotated from a set position to an end-of-dose position, whereby the trigger member is moved axially by the trigger spring, the end-of-dose switch thereby being actuated.

10. 发明申请

US20150196718A1 Medical Injection Device 有权
标题翻译：医疗注射装置
公开(公告)号：US20150196718A1
公开(公告)日：2015-07-16
申请号：US14667890
申请日：2015-03-25
申请人： Novo Nordisk A/S
发明人： Bo Radmer , Christian Plambech , Christian Hoejris Nielsen , Jesper Peter Windum , Tom Hede Markussen
IPC分类号： A61M5/32 , A61M5/24
CPC分类号： A61M5/3202 , A61M5/002 , A61M5/2466 , A61M2005/3117
摘要： The present invention relates to injection devices for injecting a dose of a medicament. The injection device (100) incorporates a housing (101), a needle assembly (150) and a cover (200). The needle assembly (150) comprises an injection needle (152,153) accommodated in a needle container (151) having an opening which in a storage state of the injection device (100) is sealed by a film seal (155). The cover may include sections (201,202) arranged movable relative to the housing (101). The injection device (100) is so configured that upon movement of the cover sections (201,202) relative to the housing (101) the film seal (155) is changed from a sealing state to an unsealing state for shifting the injection device (100) into a ready-to-administer state.
摘要翻译：本发明涉及用于注射剂量的药物的注射装置。注射装置（100）包括壳体（101），针组件（150）和盖（200）。针组件（150）包括容纳在具有开口的针容器（151）中的注射针（152,153），其在注射装置（100）的储存状态下被薄膜密封件（155）密封。盖可以包括相对于壳体（101）可移动的部分（201,202）。注射装置（100）被构造成使得当盖部（201,202）相对于壳体（101）移动时，膜密封件（155）从密封状态改变到用于移动注射装置（100）的开封状态，进入准备管理的状态。

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