专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20120143623A1 RULE BASED DECISION SUPPORT AND PATIENT-SPECIFIC VISUALIZATION SYSTEM FOR OPTIMAL CANCER STAGING 审中-公开
标题翻译：基于规则的决策支持和患者特异性可视化系统，用于最佳癌症分期
公开(公告)号：US20120143623A1
公开(公告)日：2012-06-07
申请号：US13382013
申请日：2010-06-15
申请人： Roland Johannes Opfer , Cristian Lorenz , Rafael Wiemker , Lothar Spies , Guy Shechter
发明人： Roland Johannes Opfer , Cristian Lorenz , Rafael Wiemker , Lothar Spies , Guy Shechter
IPC分类号： G06Q50/22
CPC分类号： G06T7/0012 , G06Q50/22 , G06T2200/24 , G06T2207/30061
摘要： A system including a display and a processor and a corresponding method for identifying a tumor in a patient image, classifying the tumor based on a predetermined classification system and determining a recommendation regarding a lymph node biopsy based on the tumor identified in the patient image, the classification of the tumor and a predetermined rule.
摘要翻译：一种包括显示器和处理器的系统以及用于识别患者图像中的肿瘤的相应方法，基于预定分类系统对肿瘤进行分类，并基于在患者图像中识别的肿瘤确定关于淋巴结活检的建议，肿瘤分类和预定规则。

2. 发明授权

US08103609B2 Knowledge-based input region of interest definition for pharmacokinetic modeling 失效
标题翻译：基于知识的输入兴趣定义为药代动力学建模
公开(公告)号：US08103609B2
公开(公告)日：2012-01-24
申请号：US12067481
申请日：2006-09-13
申请人： Alexander Fischer , Lothar Spies
发明人： Alexander Fischer , Lothar Spies
IPC分类号： G06F17/00 , G06N5/02
CPC分类号： G06T7/0012 , A61B5/055 , G01R33/5608 , G06K9/3233 , G06K2209/05 , G06T7/11 , G06T2207/30004
摘要： A system, apparatus, and method are based on a priori knowledge of the shape of the input function for defining an input region-if-interest (ROI) in pharmacokinetic modeling. Kinetic parameter estimation requires knowledge of tracer input activity and the present invention provides an automatic way to define an ROI for estimation of an input function that takes into account a priori knowledge of the shape of the input function based on an administered dose.
摘要翻译：系统，装置和方法基于用于在药代动力学建模中定义输入区域 - 如果兴趣（ROI）的输入函数的形状的先验知识。动力学参数估计需要了解示踪剂输入活动的知识，并且本发明提供了一种自动方式来定义用于估计输入功能的ROI，其基于施用的剂量考虑到输入功能的形状的先验知识。

3. 发明授权

US08064672B2 Patient scan time optimization for PET/SPECT imaging 有权
标题翻译： PET / SPECT成像的患者扫描时间优化
公开(公告)号：US08064672B2
公开(公告)日：2011-11-22
申请号：US12088088
申请日：2006-09-15
申请人： Manoj Narayanan , Bart Jacob Bakker , Daniel Gagnon , Alexander Fischer , Lothar Spies
发明人： Manoj Narayanan , Bart Jacob Bakker , Daniel Gagnon , Alexander Fischer , Lothar Spies
IPC分类号： G06K9/00
CPC分类号： A61B6/00 , A61B6/037
摘要： An imaging system (10) comprises a data device (30), which controls radiation data acquisition from a subject positioned in an examination region (18) for an examination. A rebinning processor (40) bins the acquired data periodically into a histogram (42). A transform (70) transforms the histogram (42) into individual independent or uncorrelated components, each component including a signal content and a noise content. A stopping determining device (52) compares an aspect of at least one selected component to a predetermined threshold (TH) and, based on the comparison, terminates the data acquisition.
摘要翻译：成像系统（10）包括数据装置（30），其控制从位于检查区域（18）中的被摄体进行检查的辐射数据采集。重组处理器（40）将获取的数据周期性地存储到直方图（42）中。变换（70）将直方图（42）变换为独立的或不相关的分量，每个分量包括信号内容和噪声内容。停止确定装置（52）将至少一个所选择的组件的方面与预定阈值（TH）进行比较，并且基于该比较，终止数据采集。

4. 发明授权

US07787669B2 Reconstruction of local patient doses in computed tomography 有权
标题翻译：计算机断层扫描中局部患者剂量的重建
公开(公告)号：US07787669B2
公开(公告)日：2010-08-31
申请号：US10543567
申请日：2004-01-19
申请人： Henrik Botterweck , Lothar Spies
发明人： Henrik Botterweck , Lothar Spies
IPC分类号： G06K9/00
CPC分类号： A61B6/032 , A61N5/1031 , Y10S128/922
摘要： In order to reduce an x-ray dose applied to a patient, it is necessary to know the dose absorbed by the patient. According to the present invention, there is provided a method of determining a local patient dose applied to a patient where after the reconstruction of the scan data into a diagnostic image, the scan data are backprojected into the patient volume, using the attenuation information of the diagnostic image to form a spatially varying photon fluence map. In parallel, the diagnostic image is segmented into anatomical structures to which dose-weighting factors are assigned. The locally absorbed dose is then calculated on the basis of the fluence map and the corresponding dose weights.
摘要翻译：为了减少施加到患者的x射线剂量，需要知道患者吸收的剂量。根据本发明，提供了一种确定施用于患者的局部患者剂量的方法，其中在将扫描数据重建为诊断图像之后，使用所述扫描数据的衰减信息将扫描数据反向投影到患者体积中诊断图像形成空间变化的光子注量图。并行地，诊断图像被分割成分配给剂量加权因子的解剖结构。然后根据注量图和相应的剂量重量计算局部吸收剂量。

5. 发明授权

US08617072B2 System for the noninvasive determination of tracer concentration in blood 失效
标题翻译：用于无创测定血液中示踪剂浓度的系统
公开(公告)号：US08617072B2
公开(公告)日：2013-12-31
申请号：US11569437
申请日：2005-05-20
申请人： Dragos-Nicolae Peligrad , Lothar Spies , Timo Paulus
发明人： Dragos-Nicolae Peligrad , Lothar Spies , Timo Paulus
IPC分类号： A61B5/00
CPC分类号： G06F19/321 , G06F19/00 , G16H10/40
摘要： The invention relates to a general composite compartmental model and a compartmental analysis procedure to extract non-invasively the concentration (Cp) of the imaging agent in plasma (301), in metabolites (304, 504) and in blood elements (303) (like red cells, platelets, plasma protein etc.) from time signal curves measured within a reference tissue region (200). This is made possible by deploying an injection function (SINJ(t)) as input which models the amount of imaging agent administered to the patient as a function of time. The invention allows the presentation of the plasma input function to the medical practitioner without the need for invasively drawing blood samples.
摘要翻译：本发明涉及一般的复合区室模型和隔室分析程序，其非侵入性地提取血浆（301），代谢物（304,504）和血液元件（303）中的成像剂的浓度（Cp）（如红细胞，血小板，血浆蛋白等）从参考组织区域（200）中测量的时间信号曲线。这是通过部署注射功能（SINJ（t））作为对作为时间的函数对患者施用的成像剂的量进行建模的输入而实现的。本发明允许向医生介绍等离子体输入功能，而不需要侵入性地抽取血液样本。

6. 发明授权

US07991243B2 Radial adaptive filter for metal artifact correction 有权
标题翻译：用于金属伪影校正的径向自适应滤波器
公开(公告)号：US07991243B2
公开(公告)日：2011-08-02
申请号：US11815215
申请日：2006-02-01
申请人： Matthieu Bal , Hasan Celik , Kai Eck , Lothar Spies , Krishna Subramanyan
发明人： Matthieu Bal , Hasan Celik , Kai Eck , Lothar Spies , Krishna Subramanyan
IPC分类号： G06K9/40 , G06K9/00 , A61B6/00
CPC分类号： G06T11/008
摘要： A diagnostic imaging system (10) corrects metal artifact streaks (38) emanating from a metal object (36) in a tomographic image (T). A first processor (40) reduces streaks (38) caused by mild artifacts by applying an adaptive filter (82). The filter (82) is perpendicularly oriented toward the center of the metal object (36). The weight of the filter (82) is a function of the local structure tensor and the vector pointing to the metal object (36). If it is determined that the strong artifacts are present in the image, a second processor (48) applies a sinogram completed image algorithm to correct for severe artifacts in the image. The sinogram completed image and adaptively filtered image are fused to a final corrected image. In the fusion process, highly corrupted tomographic regions are replaced by the result of the sinogram completed image and the remainder is replaced by the adaptively filtered image.
摘要翻译：诊断成像系统（10）校正在断层图像（T）中从金属物体（36）发出的金属假象条纹（38）。第一处理器（40）通过应用自适应滤波器（82）来减少由温和伪影引起的条纹（38）。过滤器（82）朝向金属物体（36）的中心垂直取向。过滤器（82）的重量是局部结构张量和指向金属物体（36）的矢量的函数。如果确定图像中存在强伪像，则第二处理器（48）施加正弦图完成图像算法以校正图像中的严重伪像。正弦图完成图像和自适应滤波图像融合到最终校正图像。在融合过程中，高度破坏的断层摄影区域被正弦图完成图像的结果所替代，其余部分由自适应滤波图像代替。

7. 发明申请

US20100201686A1 METHOD, APPARATUS, COMPUTER-READABLE MEDIUM AND USE FOR PHARMACOKINETIC MODELING 审中-公开
标题翻译：方法，装置，计算机可读介质和用于药物动力学建模
公开(公告)号：US20100201686A1
公开(公告)日：2010-08-12
申请号：US12671244
申请日：2007-08-03
申请人： Timo Paulus , Alexander Fischer , Lothar Spies
发明人： Timo Paulus , Alexander Fischer , Lothar Spies
IPC分类号： G06T17/00
CPC分类号： H04L51/14
摘要： Methods and systems for interworking in messaging systems are described. An event store can be accessible by different dispatchers associated with different message servers. The dispatchers may be co-located with the event store or non co-located with the event store.
摘要翻译：描述了消息系统中互通的方法和系统。可以通过与不同消息服务器相关联的不同调度器访问事件存储。调度员可以与事件存储共同定位，也可以与事件存储不同。

8. 发明授权

US07636420B2 Radio-therapeutic treatment planning incorporating functional imaging information 有权
标题翻译：包括功能成像信息的放射治疗治疗计划
公开(公告)号：US07636420B2
公开(公告)日：2009-12-22
申请号：US11914765
申请日：2006-05-01
申请人： Lothar Spies , Matthieu Bal , Todd McNutt
发明人： Lothar Spies , Matthieu Bal , Todd McNutt
IPC分类号： A61N5/10 , H05G1/42
CPC分类号： A61N5/103 , A61B6/03 , A61N5/1039 , A61N5/1042
摘要： A radiation therapy planning procedure and device provides a model-based segmentation of co-registered anatomical and functional imaging information to provide a more precise radiation therapy plan. The biology-based segmentation models the imaging information to produce a parametric map, which is then clustered into regions of similar radiation sensitivity or other biological parameters relevant for treatment definition. Each clustered region is prescribed its own radiation prescription dose.
摘要翻译：辐射治疗计划程序和装置提供共同注册的解剖和功能成像信息的基于模型的分割，以提供更精确的放射治疗计划。基于生物学的分割模拟成像信息以产生参数图，然后将其聚类到具有相似辐射敏感性的区域或与治疗定义相关的其他生物参数。每个聚簇区域规定自己的辐射处方剂量。

9. 发明申请

US20090028408A1 RADIATION THERAPY FLANNING PROCEDURE 有权
标题翻译：辐射治疗法
公开(公告)号：US20090028408A1
公开(公告)日：2009-01-29
申请号：US12162671
申请日：2007-01-22
申请人： Lothar Spies , Helga Hummel , Carolina Ribbing , Ralf Hoffmann , Peter Klaus Bachmann
发明人： Lothar Spies , Helga Hummel , Carolina Ribbing , Ralf Hoffmann , Peter Klaus Bachmann
IPC分类号： A61N5/10
CPC分类号： A61N5/1031
摘要： An improved radiation therapy planning procedure is suggested. The procedure comprises the steps of specifying and determining the absolute grade of cell degeneracy by in-vitro tests, whereby marker(s) indicative for specific cell degeneracy are detected and quantified, establishing a biology-based segmentation of areas with similar grade of relative cell degeneracy and applying the absolute grade of cell degeneracy to the biology-based segmentation data, thereby establishing an improved radiation therapy planning procedure. Moreover, the present invention suggests a system for an improved radiation therapy planning procedure and its use in procedures of diagnosis and/or therapy management of cancer
摘要翻译：建议采用改进的放射治疗计划程序。该方法包括以下步骤：通过体外测试来指定和确定细胞退化的绝对等级，由此检测和量化指示特异性细胞退化的标志物，建立具有相似等级的相对细胞的区域的基于生物学的分割退化并将绝对等级的细胞退化应用于基于生物学的分割数据，从而建立改进的放射治疗计划程序。此外，本发明提出了一种改进的放射治疗计划程序及其在癌症诊断和/或治疗管理程序中的应用的系统

10. 发明申请

US20080228686A1 Knowledge-Based Input Region of Interest Definition for Pharmacokinetic Modeling 失效
标题翻译：基于知识的输入区域药代动力学建模的兴趣定义
公开(公告)号：US20080228686A1
公开(公告)日：2008-09-18
申请号：US12067481
申请日：2006-09-13
申请人： Alexander Fischer , Lothar Spies
发明人： Alexander Fischer , Lothar Spies
IPC分类号： G06N5/02
CPC分类号： G06T7/0012 , A61B5/055 , G01R33/5608 , G06K9/3233 , G06K2209/05 , G06T7/11 , G06T2207/30004
摘要： The present invention provides a system, apparatus, and method that are based on a priori knowledge of the shape of the input function for defining an input region-if-interest (ROI) in pharmacokinetic modeling. Kinetic parameter estimation requires knowledge of tracer input activity and the present invention provides an automatic way to define an ROI for estimation of an input function that takes into account a priori knowledge of the shape of the input function based on an administered dose. As a result of the application of the present invention to existing imaging analysis systems, there is a reduction in the amount of manual interaction needed and operator dependence is thereby reduced in the evaluation of dynamic procedures.
摘要翻译：本发明提供一种系统，装置和方法，其基于用于在药代动力学建模中定义输入区域 - 如果兴趣（ROI）的输入函数的形状的先验知识。动力学参数估计需要了解示踪剂输入活动的知识，并且本发明提供了一种自动方式来定义用于估计输入功能的ROI，其基于施用的剂量考虑到输入功能的形状的先验知识。作为将本发明应用于现有成像分析系统的结果，在动态过程的评估中减少了所需的手动交互量，从而减少了操作者依赖性。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式