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1. 发明申请

US20120143623A1 RULE BASED DECISION SUPPORT AND PATIENT-SPECIFIC VISUALIZATION SYSTEM FOR OPTIMAL CANCER STAGING 审中-公开
标题翻译：基于规则的决策支持和患者特异性可视化系统，用于最佳癌症分期
公开(公告)号：US20120143623A1
公开(公告)日：2012-06-07
申请号：US13382013
申请日：2010-06-15
申请人： Roland Johannes Opfer , Cristian Lorenz , Rafael Wiemker , Lothar Spies , Guy Shechter
发明人： Roland Johannes Opfer , Cristian Lorenz , Rafael Wiemker , Lothar Spies , Guy Shechter
IPC分类号： G06Q50/22
CPC分类号： G06T7/0012 , G06Q50/22 , G06T2200/24 , G06T2207/30061
摘要： A system including a display and a processor and a corresponding method for identifying a tumor in a patient image, classifying the tumor based on a predetermined classification system and determining a recommendation regarding a lymph node biopsy based on the tumor identified in the patient image, the classification of the tumor and a predetermined rule.
摘要翻译：一种包括显示器和处理器的系统以及用于识别患者图像中的肿瘤的相应方法，基于预定分类系统对肿瘤进行分类，并基于在患者图像中识别的肿瘤确定关于淋巴结活检的建议，肿瘤分类和预定规则。

2. 发明授权

US09129360B2 Visualization apparatus for visualizing an image data set 有权
标题翻译：用于可视化图像数据集的可视化装置
公开(公告)号：US09129360B2
公开(公告)日：2015-09-08
申请号：US13376213
申请日：2010-06-02
申请人： Rafael Wiemker , Thomas Buelow , Cristian Lorenz , Torbjorn Vik , Sven Kabus
发明人： Rafael Wiemker , Thomas Buelow , Cristian Lorenz , Torbjorn Vik , Sven Kabus
IPC分类号： G09G5/02 , G06T7/00 , G06T11/00 , G06T19/00
CPC分类号： G06T7/0012 , G06T11/001 , G06T19/00 , G06T2200/24 , G06T2207/10081 , G06T2207/10088 , G06T2207/10132 , G06T2207/20021 , G06T2207/20092 , G06T2207/30064 , G06T2210/41 , G06T2219/028 , G06T2219/2012
摘要： The invention relates to a visualization apparatus (1) for visualizing an image data set. The visualization apparatus (1) comprises an image data set providing unit (2) for providing the image data set, a differential property determination unit (5) for determining local differential properties for different regions of the image data set, an assigning unit (6) for assigning visualization properties to the different regions of the image data set depending on the determined local differential properties, wherein a visualization property defines the visualization of a region, to which the visualization property is assigned, and a display unit (7) for displaying the visualization properties assigned to the different regions of the image data set. By displaying the visualization properties assigned to the different regions of the image data set different objects can visually be separated from each other without requiring large computational costs.
摘要翻译：本发明涉及一种用于可视化图像数据集的可视化装置（1）。可视化装置（1）包括用于提供图像数据组的图像数据集提供单元（2），用于确定图像数据组的不同区域的局部差分属性的差分特性确定单元（5），分配单元），用于根据所确定的本地差分属性将可视化属性分配给图像数据集的不同区域，其中可视化属性定义可分配可视化属性的区域的可视化，以及用于显示的显示单元（7）分配给图像数据集的不同区域的可视化属性。通过显示分配给图像数据集的不同区域的可视化属性，不同的对象可以在视觉上彼此分离，而不需要大的计算成本。

3. 发明申请

US20100128940A1 METHOD OF AUTOMATIC EXTRACTION OF THE PULMONARY ARTERY TREE FROM 3D MEDICAL IMAGES 有权
标题翻译：从三维医学图像中自动提取脉络膜的方法
公开(公告)号：US20100128940A1
公开(公告)日：2010-05-27
申请号：US11815662
申请日：2006-02-06
申请人： Thomas Buelow , Rafael Wiemker , Thomas Blaffert , Cristian Lorenz , Steffen Renisch
发明人： Thomas Buelow , Rafael Wiemker , Thomas Blaffert , Cristian Lorenz , Steffen Renisch
IPC分类号： G06K9/62
CPC分类号： G06T7/155 , G06T7/11 , G06T7/149 , G06T2200/04 , G06T2207/10081 , G06T2207/20044 , G06T2207/20156 , G06T2207/30061 , G06T2207/30101
摘要： An automated method (1) for the automatic extraction of a pulmonary vessel tree from a 3D medical image, such as multi-slice CT data, is disclosed. A segmented pulmonary vessel is identified as either an artery or a vein by determining a measure for arterialness for the vessel. The measure is based on a relation of the orientation of a local bronchus to the orientation of the segmented pulmonary vessel of the local bronchus. When a vessel is identified as a pulmonary artery, it is added to the pulmonary artery tree. Radii of the pulmonary artery and bronchus are measured automatically and positions where a ratio of these radii exhibits unusual values are presented in a display, preferably for suggesting further assessment by a radiologist, which for instance is useful for pulmonary embolism detection.
摘要翻译：公开了一种用于从诸如多层CT数据的3D医学图像自动提取肺血管树的自动化方法（1）。通过确定血管动脉的测量，将分段的肺血管识别为动脉或静脉。该措施基于局部支气管的取向与局部支气管的分段肺血管的取向的关系。当血管被识别为肺动脉时，将其加入肺动脉树。自动测量肺动脉和支气管的半径，并且在显示中呈现这些半径的比率显示出异常值的位置，优选用于暗示例如用于肺栓塞检测的放射科医师的进一步评估。

4. 发明授权

US07970189B2 Method of automatic extraction of the pulmonary artery tree from 3D medical images 有权
标题翻译：从3D医学图像自动提取肺动脉树的方法
公开(公告)号：US07970189B2
公开(公告)日：2011-06-28
申请号：US11815662
申请日：2006-02-06
申请人： Thomas Buelow , Rafael Wiemker , Thomas Blaffert , Cristian Lorenz , Steffen Renisch
发明人： Thomas Buelow , Rafael Wiemker , Thomas Blaffert , Cristian Lorenz , Steffen Renisch
IPC分类号： G06K9/00
CPC分类号： G06T7/155 , G06T7/11 , G06T7/149 , G06T2200/04 , G06T2207/10081 , G06T2207/20044 , G06T2207/20156 , G06T2207/30061 , G06T2207/30101
摘要： An automated method (1) for the automatic extraction of a pulmonary vessel tree from a 3D medical image, such as multi-slice CT data, is disclosed. A segmented pulmonary vessel is identified as either an artery or a vein by determining a measure for arterialness for the vessel. The measure is based on a relation of the orientation of a local bronchus to the orientation of the segmented pulmonary vessel of the local bronchus. When a vessel is identified as a pulmonary artery, it is added to the pulmonary artery tree. Radii of the pulmonary artery and bronchus are measured automatically and positions where a ratio of these radii exhibits unusual values are presented in a display, preferably for suggesting further assessment by a radiologist, which for instance is useful for pulmonary embolism detection.
摘要翻译：公开了一种用于从诸如多层CT数据的3D医学图像自动提取肺血管树的自动化方法（1）。通过确定血管动脉的测量，将分段的肺血管识别为动脉或静脉。该措施基于局部支气管的取向与局部支气管的分段肺血管的取向的关系。当血管被识别为肺动脉时，将其加入肺动脉树。自动测量肺动脉和支气管的半径，并且在显示中呈现这些半径的比率显示出异常值的位置，优选用于暗示例如用于肺栓塞检测的放射科医师的进一步评估。

5. 发明授权

US08526697B2 Apparatus for segmenting an object comprising sub-objects 有权
标题翻译：用于分割包括子对象的对象的装置
公开(公告)号：US08526697B2
公开(公告)日：2013-09-03
申请号：US12867522
申请日：2009-02-06
申请人： Thomas Blaffert , Hans Barschdorf , Jens Von Berg , Sebastian Peter Michael Dries , Cristian Lorenz , Rafael Wiemker , Tobias Klinder , Astrid Ruth Franz , Steffen Renisch
发明人： Thomas Blaffert , Hans Barschdorf , Jens Von Berg , Sebastian Peter Michael Dries , Cristian Lorenz , Rafael Wiemker , Tobias Klinder , Astrid Ruth Franz , Steffen Renisch
IPC分类号： G06K9/00
CPC分类号： G06T5/003 , G06T7/11 , G06T7/149 , G06T2207/10081 , G06T2207/20041 , G06T2207/20081 , G06T2207/20124 , G06T2207/20192 , G06T2207/30061
摘要： The present invention relates to an apparatus (1) for segmenting an object comprising sub-objects shown in an object image. The apparatus comprises a feature image generation unit (2) for generating a feature image showing features related to intermediate regions between the sub-objects and a segmentation unit (3) for segmenting the sub-objects by using the object image and the feature image. Preferentially, the feature image generation unit (2) is adapted for generating a feature image from the object image. In a further embodiment, the feature image generation unit (2) comprises a feature enhancing unit for enhancing features related to intermediate regions between the sub-objects in the object image.
摘要翻译：本发明涉及一种用于分割包含物体图像中所示的子对象的物体的装置（1）。该装置包括：特征图像生成单元，用于生成显示与子对象之间的中间区域相关的特征的特征图像和用于通过使用对象图像和特征图像来分割子对象的分割单元（3）。优选地，特征图像生成单元（2）适于从对象图像生成特征图像。在另一实施例中，特征图像生成单元（2）包括特征增强单元，用于增强与对象图像中的子对象之间的中间区域相关的特征。

6. 发明申请

US20100266173A1 COMPUTER-AIDED DETECTION (CAD) OF A DISEASE 审中-公开
标题翻译：疾病的计算机辅助检测（CAD）
公开(公告)号：US20100266173A1
公开(公告)日：2010-10-21
申请号：US12741837
申请日：2008-11-06
申请人： Cristian Lorenz , Jens Von Berg , Thomas Buelow , Rafael Wiemker
发明人： Cristian Lorenz , Jens Von Berg , Thomas Buelow , Rafael Wiemker
IPC分类号： G06K9/00
CPC分类号： G06T7/0012 , G06T7/11 , G06T2200/24 , G06T2207/10072 , G06T2207/30061
摘要： The present invention relates to a method for performing computer-aided detection (CAD) of a disease, e.g. lung tumours, on a medical image data set (20) from a imaging modality, such as MRI or CT. Initially, there is perform a segmentation of the medical image data set (20) using an anatomical model. Secondly, the segmented data is analyzed for characteristics of the disease resulting in a set of analysis data (25), and finally the set of analysis data (25) is evaluating with respect to the disease. At least one of these steps comprises as an input a position dependent probability (P_r) for the disease. The invention is advantageous in that more efficient computations can be performed because the degree of analysis in a certain region of the part of the patient, e.g. the lung, can be adjusted or tailored to the level of probability of the disease in the that region. It is thereby possible to increase computational speed and thereby diseases like cancer, in particular cancer nodules in the lungs, can be more effectively found from medical image analysis.
摘要翻译：本发明涉及用于执行疾病的计算机辅助检测（CAD）的方法，例如，肺肿瘤，来自成像模态（例如MRI或CT）的医学图像数据集（20）。最初，使用解剖模型执行医学图像数据集（20）的分割。其次，对分割的数据进行分析，得到一组分析数据（25），最后分析数据集（25）正在评估疾病。这些步骤中的至少一个包括用于疾病的位置依赖概率（P_r）作为输入。本发明的优点在于，可以执行更有效的计算，因为患者部分的某个区域中的分析程度，例如，肺，可以根据该区域的疾病概率进行调整或调整。从而可以增加计算速度，从而可以从医学图像分析中更有效地发现像癌症，特别是肺中的癌症结节之类的疾病。

7. 发明申请

US20080071160A1 Displaying A Tracheobronchial Tree 审中-公开
标题翻译：显示气管支气管树
公开(公告)号：US20080071160A1
公开(公告)日：2008-03-20
申请号：US11570517
申请日：2005-06-15
申请人： Rafael Wiemker , Thomas Blaffert , Thomas Buelow , Steffen Renisch , Cristian Lorenz , Hans-Aloys Wischmann
发明人： Rafael Wiemker , Thomas Blaffert , Thomas Buelow , Steffen Renisch , Cristian Lorenz , Hans-Aloys Wischmann
IPC分类号： A61B5/04
CPC分类号： G06T11/206 , G06T7/12 , G06T7/62 , G06T2207/10072 , G06T2207/30028 , G06T2207/30061
摘要： The invention relates to automatically segmenting and displaying the tracheobronchial tree (400) and displaying clinical values (404) related to the segmented tracheobronchial tree (400).
摘要翻译：本发明涉及自动分割和显示气管支气管（400）并显示与分段的气管支气管结石（400）相关的临床值（404）。

8. 发明授权

US08892188B2 Identifying abnormal tissue in images of computed tomography 有权
标题翻译：识别计算机断层扫描图像中的异常组织
公开(公告)号：US08892188B2
公开(公告)日：2014-11-18
申请号：US11815973
申请日：2006-02-03
申请人： Thomas Buelow , Rafael Wiemker , Cristian Lorenz , Steffen Renisch , Thomas Blaffert
发明人： Thomas Buelow , Rafael Wiemker , Cristian Lorenz , Steffen Renisch , Thomas Blaffert
IPC分类号： A61B6/03 , G06T7/00 , G06K9/34 , A61B6/00
CPC分类号： G06T7/0012 , A61B6/032 , A61B6/481 , A61B6/5217 , G06T5/50 , G06T7/10 , G06T7/12 , G06T7/149 , G06T2207/10081 , G06T2207/10116 , G06T2207/30061 , G06T2207/30064 , G06T2207/30101
摘要： An imaging method for identifying abnormal tissue in the lung is provided, comprising the recording of slice images of the lung by means of X-ray radiation, recording of blood vessels, differentiation of blood vessels and abnormal tissue, segmentation of the abnormal tissue and display of the segmented abnormal tissue on an output device. In addition, a computer tomograph for identifying abnormal tissue in the lung is provided, having a radiation source for recording slice images of the lung and blood vessels by means of X-ray radiation, a computer unit for differentiating the blood vessels from the abnormal tissue and for segmenting the abnormal tissue, as well as an output device for displaying the segmented abnormal tissue. Furthermore, a computer program is provided for controlling a computer tomograph for an identification of abnormal tissue in the lung by means of a radiation source, designed to record slice images of the lung and blood vessels by means of X-ray radiation, to differentiate the blood vessels from abnormal tissue, to segment the abnormal tissue and to control an output device for displaying the abnormal tissue.
摘要翻译：提供了一种用于鉴定肺中异常组织的成像方法，包括通过X射线照射记录肺的切片图像，记录血管，血管和异常组织的分化，异常组织的分割和显示的输出装置上的分段异常组织。另外，提供了一种用于识别肺中的异常组织的计算机断层摄影机，具有用于通过X射线辐射记录肺和血管的切片图像的辐射源，用于将血管与异常组织分离的计算机单元并且用于分割异常组织，以及用于显示分段的异常组织的输出装置。此外，提供了一种计算机程序，用于通过辐射源来控制用于识别肺中的异常组织的计算机断层摄影机，其被设计成通过X射线辐射记录肺和血管的切片图像，以区分来自异常组织的血管，分割异常组织并控制用于显示异常组织的输出装置。

9. 发明申请

US20110052018A1 APPARATUS FOR SEGMENTING AN OBJECT COMPRISING SUB-OBJECTS 有权
标题翻译：用于分配包含子对象的对象的设备
公开(公告)号：US20110052018A1
公开(公告)日：2011-03-03
申请号：US12867522
申请日：2009-02-06
申请人： Thomas Blaffert , Hans Barschdorf , Jans Von Berg , Sebastian Peter Michael Dries , Cristian Lorenz , Rafael Wiemker , Tobias Klinder , Astrid Ruth Franz , Steffen Renisch
发明人： Thomas Blaffert , Hans Barschdorf , Jans Von Berg , Sebastian Peter Michael Dries , Cristian Lorenz , Rafael Wiemker , Tobias Klinder , Astrid Ruth Franz , Steffen Renisch
IPC分类号： G06K9/00 , G06K9/34
CPC分类号： G06T5/003 , G06T7/11 , G06T7/149 , G06T2207/10081 , G06T2207/20041 , G06T2207/20081 , G06T2207/20124 , G06T2207/20192 , G06T2207/30061
摘要： The present invention relates to an apparatus (1) for segmenting an object comprising sub-objects shown in an object image. The apparatus comprises a feature image generation unit (2) for generating a feature image showing features related to intermediate regions between the sub-objects and a segmentation unit (3) for segmenting the sub-objects by using the object image and the feature image. Preferentially, the feature image generation unit (2) is adapted for generating a feature image from the object image. In a further embodiment, the feature image generation unit (2) comprises a feature enhancing unit for enhancing features related to intermediate regions between the sub-objects in the object image.
摘要翻译：本发明涉及一种用于分割包含物体图像中所示的子对象的物体的装置（1）。该装置包括：特征图像生成单元，用于生成显示与子对象之间的中间区域相关的特征的特征图像和用于通过使用对象图像和特征图像来分割子对象的分割单元（3）。优选地，特征图像生成单元（2）适于从对象图像生成特征图像。在另一实施例中，特征图像生成单元（2）包括特征增强单元，用于增强与对象图像中的子对象之间的中间区域相关的特征。

10. 发明申请

US20080269598A1 Identifying Abnormal Tissue in Images of Computed Tomography 有权
标题翻译：识别计算机断层扫描图像中的异常组织
公开(公告)号：US20080269598A1
公开(公告)日：2008-10-30
申请号：US11815973
申请日：2006-02-03
申请人： Thomas Buelow , Rafael Wiemker , Cristian Lorenz , Steffen Renisch , Thomas Blaffert
发明人： Thomas Buelow , Rafael Wiemker , Cristian Lorenz , Steffen Renisch , Thomas Blaffert
IPC分类号： A61B5/05 , G06K9/00
CPC分类号： G06T7/0012 , A61B6/032 , A61B6/481 , A61B6/5217 , G06T5/50 , G06T7/10 , G06T7/12 , G06T7/149 , G06T2207/10081 , G06T2207/10116 , G06T2207/30061 , G06T2207/30064 , G06T2207/30101
摘要： An imaging method for identifying abnormal tissue in the lung is provided, comprising the recording of slice images of the lung by means of X-ray radiation, recording of blood vessels, differentiation of blood vessels and abnormal tissue, segmentation of the abnormal tissue and display of the segmented abnormal tissue on an output device. In addition, a computer tomograph for identifying abnormal tissue in the lung is provided, having a radiation source for recording slice images of the lung and blood vessels by means of X-ray radiation, a computer unit for differentiating the blood vessels from the abnormal tissue and for segmenting the abnormal tissue, as well as an output device for displaying the segmented abnormal tissue. Furthermore, a computer program is provided for controlling a computer tomograph for an identification of abnormal tissue in the lung by means of a radiation source, designed to record slice images of the lung and blood vessels by means of X-ray radiation, to differentiate the blood vessels from abnormal tissue, to segment the abnormal tissue and to control an output device for displaying the abnormal tissue.
摘要翻译：提供了一种用于鉴定肺中异常组织的成像方法，包括通过X射线照射记录肺的切片图像，记录血管，血管和异常组织的分化，异常组织的分割和显示的输出装置上的分段异常组织。另外，提供了一种用于识别肺中的异常组织的计算机断层摄影机，具有用于通过X射线辐射记录肺和血管的切片图像的辐射源，用于将血管与异常组织分离的计算机单元并且用于分割异常组织，以及用于显示分段的异常组织的输出装置。此外，提供了一种计算机程序，用于通过辐射源来控制用于识别肺中的异常组织的计算机断层摄影机，其被设计成通过X射线辐射记录肺和血管的切片图像，以区分来自异常组织的血管，分割异常组织并控制用于显示异常组织的输出装置。

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