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1. 发明申请

US20190070276A1 Use of Car and Bite Technology Coupled with an SCFV from an Antibody Against Human Thymidine Kinase 1 to Specifically Target Tumors 审中-公开
公开(公告)号：US20190070276A1
公开(公告)日：2019-03-07
申请号：US16122557
申请日：2018-09-05
申请人： Kim Leslie O'Neill , Scott Weber
发明人： Kim Leslie O'Neill , Scott Weber
IPC分类号： A61K39/00 , C07K16/46 , C07K16/28 , C07K16/40
摘要： Modified T-cells have paratopes against human TK1 epitopes, are made by producing monoclonal antibodies that are specific to TK1, creating chimeric antigen receptors (CARs) by fusion of the single-chain variable fragments (scFv) of the monoclonal antibodies to T-cell signalling domains, and transducing the CARs to the T-cells.

2. 发明授权

US09396461B2 Adjusting different areas of a payment instrument image independently 有权
标题翻译：独立调整支付工具图像的不同区域
公开(公告)号：US09396461B2
公开(公告)日：2016-07-19
申请号：US14256425
申请日：2014-04-18
申请人： Scott Weber , Rian Maloney
发明人： Scott Weber , Rian Maloney
IPC分类号： G06Q20/04 , G06K9/03 , G06Q40/00
CPC分类号： G06Q20/042 , G06K9/00469 , G06K9/036 , G06K2209/01 , G06Q20/0425
摘要： The present disclosure involves systems, software, and computer-implemented methods for allowing independent adjustment for different areas of a payment instrument image. An example method includes updating an image property of an area of a clearing payment instrument image associated with a tangible payment instrument including a payee, a payor, an amount, and an authorization, the tangible payment instrument to be submitted for electronic transaction clearing, wherein the clearing payment instrument image is associated with a first value of the image property, the image property of the area is updated to a second value different than the first value of the image property, and the area of the clearing payment instrument image includes less than the entire clearing payment image; and storing the updated clearing payment instrument image in response to updating the image property.
摘要翻译：本公开涉及用于允许对支付工具图像的不同区域进行独立调整的系统，软件和计算机实现的方法。示例性方法包括更新与包括收款人，付款人，金额和授权有关的有形支付工具相关联的结算支付工具图像的区域的图像属性，即要提交用于电子交易清算的有形支付工具，其中清算支付工具图像与图像属性的第一值相关联，该区域的图像属性被更新为与图像属性的第一值不同的第二值，并且清算支付工具图像的区域包括小于整个清算付款形象; 以及响应于更新所述图像属性而存储所述更新的清除支付工具图像。

3. 发明申请

US20150302244A1 ADJUSTING DIFFERENT AREAS OF A PAYMENT INSTRUMENT IMAGE INDEPENDENTLY 有权
标题翻译：独立调整付款仪器图像的不同领域
公开(公告)号：US20150302244A1
公开(公告)日：2015-10-22
申请号：US14256425
申请日：2014-04-18
申请人： Scott Weber , Rian Maloney
发明人： Scott Weber , Rian Maloney
IPC分类号： G06K9/00 , G06Q20/04
CPC分类号： G06Q20/042 , G06K9/00469 , G06K9/036 , G06K2209/01 , G06Q20/0425
摘要： The present disclosure involves systems, software, and computer-implemented methods for allowing independent adjustment for different areas of a payment instrument image. An example method includes updating an image property of an area of a clearing payment instrument image associated with a tangible payment instrument including a payee, a payor, an amount, and an authorization, the tangible payment instrument to be submitted for electronic transaction clearing, wherein the clearing payment instrument image is associated with a first value of the image property, the image property of the area is updated to a second value different than the first value of the image property, and the area of the clearing payment instrument image includes less than the entire clearing payment image; and storing the updated clearing payment instrument image in response to updating the image property.
摘要翻译：本公开涉及用于允许对支付工具图像的不同区域进行独立调整的系统，软件和计算机实现的方法。示例性方法包括更新与包括收款人，付款人，金额和授权有关的有形支付工具相关联的清算支付工具图像的区域的图像属性，即要提交用于电子交易清算的有形支付工具，其中清算支付工具图像与图像属性的第一值相关联，该区域的图像属性被更新为与图像属性的第一值不同的第二值，并且清算支付工具图像的区域包括小于整个清算付款形象; 以及响应于更新所述图像属性而存储所述更新的清除支付工具图像。

4. 发明申请

US20070172875A1 Compositions and Methods for Nucleic Acid Extraction from Biological Samples 审中-公开
标题翻译：从生物样品中提取核酸的组合物和方法
公开(公告)号：US20070172875A1
公开(公告)日：2007-07-26
申请号：US11688077
申请日：2007-03-19
申请人： Scott Weber , Derek Douglas , Carol Kreader
发明人： Scott Weber , Derek Douglas , Carol Kreader
IPC分类号： C12Q1/68 , C12P19/34 , C12N1/08
CPC分类号： C12N15/1003
摘要： Methods and compositions for extracting nucleic acids from a biological sample are provided. The extraction compositions contain a protease enzyme such as proteinase K at alkaline pH with little or no surfactant present. Extraction can be efficiently performed in 60 minutes or less at room temperature for certain mammalian tissue samples and at elevated temperatures for certain plant tissues.
摘要翻译：提供了从生物样品中提取核酸的方法和组合物。提取组合物在碱性pH下含有蛋白酶K，例如蛋白酶K，几乎不存在或不存在表面活性剂。对于某些哺乳动物组织样品，在某些植物组织的高温下，可以在室温下在60分钟以内有效地进行提取。

5. 发明申请

US20220372170A1 Macrophage CAR (MOTO-CAR) In Immunotherapy 有权
公开(公告)号：US20220372170A1
公开(公告)日：2022-11-24
申请号：US17833149
申请日：2022-06-06
申请人： Kim Leslie O'Neill , Scott Weber
发明人： Kim Leslie O'Neill , Scott Weber
IPC分类号： C07K16/40 , C07K14/705 , C07K14/57 , C07K16/28 , C07K16/18 , C12N5/0786 , A61K35/15 , C07K16/30
摘要： Modified macrophage immune cells are provided for treatment of cancer and other diseases. In particular said macrophages express chimeric antigen receptors (CAR). The single chain variable fragment (scFv) may be directed against thymidine kinase 1 (TK1) or hypoxanthine guanine phosphoribosyltransferase (HPRT). The signaling domain may be derived from a Toll-like receptor (TLR).

6. 发明申请

US20170249603A9 ADJUSTING DIFFERENT AREAS OF A PAYMENT INSTRUMENT IMAGE INDEPENDENTLY 审中-公开
公开(公告)号：US20170249603A9
公开(公告)日：2017-08-31
申请号：US15213088
申请日：2016-07-18
申请人： Scott Weber , Rian Maloney
发明人： Scott Weber , Rian Maloney
IPC分类号： G06Q20/04 , G06K9/00
CPC分类号： G06Q20/042 , G06K9/00469 , G06K9/036 , G06K2209/01 , G06Q20/0425
摘要： The present disclosure involves systems, software, and computer-implemented methods for allowing independent adjustment for different areas of a payment instrument image. An example method includes updating an image property of an area of a clearing payment instrument image associated with a tangible payment instrument including a payee, a payor, an amount, and an authorization, the tangible payment instrument to be submitted for electronic transaction clearing, wherein the clearing payment instrument image is associated with a first value of the image property, the image property of the area is updated to a second value different than the first value of the image property, and the area of the clearing payment instrument image includes less than the entire clearing payment image; and storing the updated clearing payment instrument image in response to updating the image property.

7. 发明申请

US20150243460A1 PARTICULATE AND PRESSURE REDIRECTION SHIELD FOR AN ELECTRIC CIRCUIT BREAKER 有权
标题翻译：用于电路断路器的颗粒和压力重定向屏蔽
公开(公告)号：US20150243460A1
公开(公告)日：2015-08-27
申请号：US14188886
申请日：2014-02-25
申请人： Scott Weber
发明人： Scott Weber
IPC分类号： H01H33/53
CPC分类号： H01H33/53 , H01H9/30 , H01H9/342 , H01H73/18 , H01H2009/305 , H01H2033/888
摘要： Featured is a particulate and pressure redirection barrier for an electrical breaker as well as a breaker embodying such a barrier. Such a barrier includes first through fifth segments, where the first segment includes a first and second side section and a bottom section that are coupled to each other so as to form a generally U shaped structure. The second segment is coupled to the first side section so it extends outwardly at an angle from the first side section. The third segment is coupled to the second side section so as to extend outwardly and at an angle from the second side section. The fourth segment is coupled to the second segment so as to extend outwardly from and at an angle with respect to the second segment. The fifth segment is coupled to the third segment so as to extend outwardly from and at an angle with respect to the third segment. Such a configuration of the fourth and fifth segments is such that gas flowing along a surface of the second or third segments is redirected at an angle with respect to that surface.
摘要翻译：特色是用于电气断路器的微粒和压力重定向屏障以及体现这种屏障的断路器。这样的屏障包括第一至第五部分，其中第一部分包括第一和第二侧部分以及彼此联接以形成大致U形结构的底部部分。第二段联接到第一侧部分，使得其从第一侧部分以一定角度向外延伸。第三段与第二侧部分相连，从而与第二侧部分向外并成一定角度。第四段联接到第二段，以便相对于第二段向外延伸并以一定角度延伸。第五段联接到第三段，以便相对于第三段从一个角度向外延伸。第四和第五段的这种构造使得沿着第二或第三段的表面流动的气体相对于该表面以一定角度被重定向。

8. 发明申请

US20110049299A1 Aircraft Cabin Door Pressure Vent System 有权
标题翻译：飞机舱门压力排气系统
公开(公告)号：US20110049299A1
公开(公告)日：2011-03-03
申请号：US12874061
申请日：2010-09-01
申请人： Greg Gowing , Scott Weber , Elisabeth Archibald , Shad Plante , Matt Wiley
发明人： Greg Gowing , Scott Weber , Elisabeth Archibald , Shad Plante , Matt Wiley
IPC分类号： B64C1/14
CPC分类号： B64C1/1461 , B64C1/14 , B64C1/1407 , B64C1/143
摘要： Disclosed is an aircraft door including a handle-activated pressure relief system that avoids potentially dangerous pressure differences between the cabin and the atmosphere outside the aircraft. A flow path is created between the inboard and outboard handles on the door. A pressure vent door is located in the flow path. The vent door being is opened when either of the inboard and outboard handle assemblies are activated. Once either handle is rotated beyond a particular point, a spring in the supporting mechanics becomes over-center. At the same time, the vent door comes under the influence of a magnet, snapping the vent open. After the door has been opened, it can be relatched by operating the handles in the reverse direction. The magnet and spring hold the vent door open until the aircraft door is fully latched, sealed, and secured. Only then does the vent door sealingly close.
摘要翻译：公开了一种飞机门，其包括手柄启动的压力释放系统，其避免了机舱和飞机外部的大气之间潜在的危险压力差。在门上的内侧和外侧手柄之间形成流路。压力通风门位于流路中。当内侧和外侧手柄组件中的任一个被启动时，通风门被打开。一旦任一个手柄旋转超过特定点，支撑力学中的弹簧变得越过中心。同时，通风门受到磁铁的影响，将通风口打开。门打开后，可以通过相反方向操作手柄来重新配置。磁体和弹簧将通风门打开，直到飞机门完全锁定，密封和固定。只有这样，通风门密封地关闭。

9. 发明申请

US20070166752A1 Compositions and Methods for Nucleic Acid Extraction from Biological Samples 审中-公开
公开(公告)号：US20070166752A1
公开(公告)日：2007-07-19
申请号：US11688071
申请日：2007-03-19
申请人： Scott Weber , Derek Douglas , Carol Kreader
发明人： Scott Weber , Derek Douglas , Carol Kreader
IPC分类号： C12Q1/68 , C12N1/08
CPC分类号： C12N15/1003
摘要： Methods and compositions for extracting nucleic acids from a biological sample are provided. The extraction compositions contain a protease enzyme such as proteinase K at alkaline pH with little or no surfactant present. Extraction can be efficiently performed in 60 minutes or less at room temperature for certain mammalian tissue samples and at elevated temperatures for certain plant tissues.

10. 发明申请

US20060276565A1 Retroflective polymeric compounds and articles made from them 审中-公开
标题翻译：由它们制成的反光聚合物和制品
公开(公告)号：US20060276565A1
公开(公告)日：2006-12-07
申请号：US10570932
申请日：2004-09-03
申请人： Craig Polta , Scott Weber
发明人： Craig Polta , Scott Weber
IPC分类号： F21V7/22
CPC分类号： C08K7/20 , C08K3/08 , C08K3/40 , C08K7/00
摘要： A retroflective polymeric compound is disclosed. The compound includes a thermoplastic polymer, glass micro-spheres, and metallic flakes. At least some of the glass microspheres are metallically coated. The metallic flakes are preferably aluminum. Optionally, colorants can be included in the polymeric compound. Articles made from the polymeric compound are also disclosed.
摘要翻译：公开了一种反射聚合物。该化合物包括热塑性聚合物，玻璃微球和金属薄片。至少一些玻璃微球体是金属涂层的。金属薄片优选为铝。任选地，着色剂可以包括在聚合物中。还公开了由聚合物制成的制品。

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