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1. 发明申请

US20090185714A1 Method and apparatus for analysis of particles in a liquid sample 有权
标题翻译：用于分析液体样品中颗粒的方法和装置
公开(公告)号：US20090185714A1
公开(公告)日：2009-07-23
申请号：US12314759
申请日：2008-12-16
申请人： Stellan Lindberg , Tom Olesen , Martin Valvik
发明人： Stellan Lindberg , Tom Olesen , Martin Valvik
IPC分类号： G06K9/00
CPC分类号： G06T7/40 , B01L3/502715 , B01L2200/0647 , B01L2300/069 , G01N15/1434 , G01N15/1456 , G01N2015/1445 , G06T2207/10056
摘要： The invention relates to methods for analysis of particles in a liquid sample, the sample being retained in a sample retaining device, the method comprising: acquiring, by means of an image acquiring device, a plurality of images of said sample at different focus planes within the sample retaining device; analysing said images, by means of an image analyser, for identifying which, if any, of the particles of the sample are imaged in focus in each of the images, and analysing those particles which have been identified as being imaged in focus; wherein said plurality of images are acquired at different, essentially parallel, focus planes, which planes are separated from each other by a distance, said distance being less than 10 micrometers. The invention also relates to apparatuses adapted to be used for the inventive methods.
摘要翻译：本发明涉及用于分析液体样品中的颗粒的方法，样品保留在样品保持装置中，该方法包括：通过图像获取装置获取在不同聚焦平面内的所述样品的多个图像，样品保持装置; 通过图像分析器分析所述图像，用于识别在每个图像中哪个样本的颗粒（如果有的话）被聚焦成像，并且分析已被识别为焦点成像的那些颗粒; 其中所述多个图像在不同的基本平行的聚焦平面上获取，所述多个平面相互间隔开一定距离，所述距离小于10微米。本发明还涉及适用于本发明方法的设备。

2. 发明申请

US20080019584A1 Measurement apparatus, method and computer program 有权
标题翻译：测量装置，方法和计算机程序
公开(公告)号：US20080019584A1
公开(公告)日：2008-01-24
申请号：US11822159
申请日：2007-07-02
申请人： Stellan Lindberg , Tom Olesen
发明人： Stellan Lindberg , Tom Olesen
IPC分类号： G06K9/00
CPC分类号： G01N15/1475 , G01N15/1463 , G01N2015/008 , G06K9/00134 , G06T7/0012 , G06T2207/30024
摘要： A measurement apparatus for enumeration of particles or white blood cells in a sample comprises: a holder, which is arranged to receive a sample acquiring device that holds a sample, an imaging system, comprising a magnifying means and at least one digital image acquiring means, said imaging system being arranged to acquire at least one digital image of the sample, and an image analyser, which is arranged to analyse the digital image for identifying particles or white blood cells and determining the number of particles or white blood cells and which is arranged to analyse the digital image for identifying particles or white blood cells that are imaged in focus, determining types of these particles or white blood cells, the types being distinguished by physical features and determining the ratio of different types of particles or white blood cells.
摘要翻译：用于计量样品中的颗粒或白细胞的测量装置包括：保持器，其布置成接收保持样品的样本获取装置，成像系统，包括放大装置和至少一个数字图像获取装置，所述成像系统被布置成获取所述样本的至少一个数字图像，以及图像分析器，其被配置为分析用于识别颗粒或白细胞的数字图像并且确定颗粒或白细胞的数量并且被布置分析用于鉴别聚焦成像的颗粒或白细胞的数字图像，确定这些颗粒或白细胞的类型，其类型由身体特征区分并确定不同类型的颗粒或白细胞的比例。

3. 发明授权

US08224058B2 Measurement apparatus, method and computer program 有权
标题翻译：测量装置，方法和计算机程序
公开(公告)号：US08224058B2
公开(公告)日：2012-07-17
申请号：US11822159
申请日：2007-07-02
申请人： Stellan Lindberg , Tom Olesen
发明人： Stellan Lindberg , Tom Olesen
IPC分类号： G06K9/00
CPC分类号： G01N15/1475 , G01N15/1463 , G01N2015/008 , G06K9/00134 , G06T7/0012 , G06T2207/30024
摘要： A measurement apparatus for enumeration of particles or white blood cells in a sample comprises: a holder, which is arranged to receive a sample acquiring device that holds a sample, an imaging system, comprising a magnifying means and at least one digital image acquiring means, said imaging system being arranged to acquire at least one digital image of the sample, and an image analyser, which is arranged to analyse the digital image for identifying particles or white blood cells and determining the number of particles or white blood cells and which is arranged to analyse the digital image for identifying particles or white blood cells that are imaged in focus, determining types of these particles or white blood cells, the types being distinguished by physical features and determining the ratio of different types of particles or white blood cells.
摘要翻译：用于计量样品中的颗粒或白细胞的测量装置包括：保持器，其布置成接收保持样品的样本获取装置，成像系统，包括放大装置和至少一个数字图像获取装置，所述成像系统被布置成获取所述样本的至少一个数字图像，以及图像分析器，其被配置为分析用于识别颗粒或白细胞的数字图像并且确定颗粒或白细胞的数量并且被布置分析用于鉴别聚焦成像的颗粒或白细胞的数字图像，确定这些颗粒或白细胞的类型，其类型由身体特征区分并确定不同类型的颗粒或白细胞的比例。

4. 发明授权

US08009894B2 Method and apparatus for analysis of particles in a liquid sample 有权
标题翻译：用于分析液体样品中颗粒的方法和装置
公开(公告)号：US08009894B2
公开(公告)日：2011-08-30
申请号：US12314759
申请日：2008-12-16
申请人： Stellan Lindberg , Tom Olesen , Martin Valvik
发明人： Stellan Lindberg , Tom Olesen , Martin Valvik
IPC分类号： G06K9/00
CPC分类号： G06T7/40 , B01L3/502715 , B01L2200/0647 , B01L2300/069 , G01N15/1434 , G01N15/1456 , G01N2015/1445 , G06T2207/10056
摘要： The invention relates to methods for analysis of particles in a liquid sample, the sample being retained in a sample retaining device, the method comprising: acquiring, by means of an image acquiring device, a plurality of images of said sample at different focus planes within the sample retaining device; analysing said images, by means of an image analyser, for identifying which, if any, of the particles of the sample are imaged in focus in each of the images, and analysing those particles which have been identified as being imaged in focus; wherein said plurality of images are acquired at different, essentially parallel, focus planes, which planes are separated from each other by a distance, said distance being less than 10 micrometers. The invention also relates to apparatuses adapted to be used for the inventive methods.
摘要翻译：本发明涉及用于分析液体样品中的颗粒的方法，样品保留在样品保持装置中，该方法包括：通过图像获取装置获取在不同聚焦平面内的所述样品的多个图像，样品保持装置; 通过图像分析器分析所述图像，用于识别在每个图像中哪个样本的颗粒（如果有的话）被聚焦成像，并且分析已被识别为焦点成像的那些颗粒; 其中所述多个图像在不同的基本平行的聚焦平面上获取，所述多个平面相互间隔开一定距离，所述距离小于10微米。本发明还涉及适用于本发明方法的设备。

5. 发明申请

US20090185734A1 Apparatus and method for analysis of particles in a liquid sample 审中-公开
标题翻译：用于分析液体样品中颗粒的装置和方法
公开(公告)号：US20090185734A1
公开(公告)日：2009-07-23
申请号：US12314838
申请日：2008-12-17
申请人： Stellan Lindberg , Tom Olesen , Martin Valvik
发明人： Stellan Lindberg , Tom Olesen , Martin Valvik
IPC分类号： G06K9/00 , G01N33/48
CPC分类号： G06K9/00134
摘要： The invention relates to a measurement apparatus, and method, for analysis of particles in a liquid sample, the apparatus comprising: an image acquiring device, an image analyser, a holder arranged to hold a sample retaining device, and a light refractor positioned between said image acquiring device and said holder; whereby at least one of the image acquiring device, the light refractor and the holder is movable by means of a piezoelectric motor, thereby moving a focus plane within the sample retaining device when it is held by the holder whereby the image acquiring device is adapted to acquire a plurality of images of said sample at different focus planes within the sample retaining device; wherein the image analyser is arranged to analyse at least one acquired image for identifying which of the particles are imaged in focus, and analysing those particles which have been identified as being imaged in focus.
摘要翻译：本发明涉及一种用于分析液体样品中的颗粒的测量装置和方法，该装置包括：图像获取装置，图像分析器，设置成保持样品保持装置的保持器和位于所述图像获取装置和所述保持器; 由此图像获取装置，光折射器和保持器中的至少一个可以通过压电电动机移动，从而当由保持器保持时移动样品保持装置内的聚焦平面，由此图像获取装置适于在样品保持装置内的不同聚焦平面处获取所述样品的多个图像; 其中所述图像分析器被布置成分析至少一个获取的图像，用于识别聚焦中的哪个颗粒成像，并且分析已经被识别为焦点成像的那些颗粒。

6. 发明申请

US20080170772A1 Apparatus for determining positions of objects contained in a sample 审中-公开
标题翻译：用于确定样品中包含的物体的位置的装置
公开(公告)号：US20080170772A1
公开(公告)日：2008-07-17
申请号：US11998416
申请日：2007-11-30
申请人： Stellan Lindberg , Tom Olesen
发明人： Stellan Lindberg , Tom Olesen
IPC分类号： G06K9/00
CPC分类号： G01N15/1463 , G01N2015/1447 , G01N2015/1486
摘要： The invention relates to an apparatus for determining positions of objects contained within a sample. The apparatus comprises an image sensor configured to transform incident light to image data, an optical system comprising a lens arrangement and an aperture, a light emitting device configured to generate light towards said image sensor, and an image data processor configured to receive image data from said image sensor and to determine positions for objects in said image data. The optical system is configured such that a depth of field of said optical system is larger than or equal to a thickness of said sample.
摘要翻译：本发明涉及一种用于确定样品中所含物体位置的装置。该装置包括被配置为将入射光转换成图像数据的图像传感器，包括透镜装置和光圈的光学系统，配置成朝向所述图像传感器产生光的发光装置，以及被配置为从所述图像传感器并且确定所述图像数据中的对象的位置。光学系统被配置为使得所述光学系统的景深大于或等于所述样品的厚度。

7. 发明申请

US20120244519A1 SYSTEM AND METHOD FOR TIME-RELATED MICROSCOPY OF BIOLOGICAL ORGANISMS 有权
标题翻译：用于生物有机体时间相关显微镜的系统和方法
公开(公告)号：US20120244519A1
公开(公告)日：2012-09-27
申请号：US13513500
申请日：2010-12-01
申请人： Tom Olesen , Martin Christian Valvik , Niels Agersnap Larsen
发明人： Tom Olesen , Martin Christian Valvik , Niels Agersnap Larsen
IPC分类号： C12M1/34 , C12Q1/70 , A01N1/02 , G01N21/00
CPC分类号： G02B21/0004 , C12Q1/18 , G02B21/365
摘要： The invention relates to a system and a method for determination of a value for at least one parameter describing microbial activity of individual biological organisms in a liquid sample. Images, wherein individual biological organisms may be identified, are combined to provide optical sectionings of the biological organisms and the optical sectionings are analysed to determine the value for said at least one parameter describing microbial activity of said individual biological organisms in each sample container.
摘要翻译：本发明涉及用于确定描述液体样品中各种生物体的微生物活性的至少一个参数的值的系统和方法。组合可以识别个体生物体的图像以提供生物生物体的光学切片，并且分析光学切片以确定描述每个样品容器中所述各个生物体的微生物活性的所述至少一个参数的值。

8. 发明申请

US20080309193A1 Electro-Mechanical Wave Device 有权
标题翻译：机电波装置
公开(公告)号：US20080309193A1
公开(公告)日：2008-12-18
申请号：US12091839
申请日：2006-10-27
申请人： Henning Ellesgaard , Elvind Johansen , Tom Olesen , Henrik Andersen , Morten Hartvig Hansen
发明人： Henning Ellesgaard , Elvind Johansen , Tom Olesen , Henrik Andersen , Morten Hartvig Hansen
IPC分类号： H02N2/16
CPC分类号： H05K1/0271 , H02N2/163 , H05K1/181 , H05K2201/09063 , H05K2201/10083 , H05K2201/2045
摘要： An electro-mechanical wave device which may be used for movement of a mechanical member, e.g. by friction, a motor comprising one or more wave devices, and a method of providing the electro-mechanical wave device. The electro-mechanical wave device comprises a substrate comprising a plurality of conductors, and a plurality of actuators positioned on the substrate for generation of mechanical waves along a predetermined propagation path, each of the actuators being connected to a respective set of the conductors of the substrate for reception of an excitation signal transmitted by the set of conductors.
摘要翻译：可以用于机械构件的运动的机电波装置，例如，通过摩擦，包括一个或多个波浪装置的马达以及提供机电波装置的方法。机电波装置包括包括多个导体的基板和位于基板上的多个致动器，用于沿着预定传播路径产生机械波，每个致动器连接到相应的一组导体用于接收由该组导体发送的激励信号的基板。

9. 发明授权

US09915813B2 System and method for time-related microscopy of biological organisms 有权
公开(公告)号：US09915813B2
公开(公告)日：2018-03-13
申请号：US13513500
申请日：2010-12-01
申请人： Tom Olesen , Martin Christian Valvik , Niels Agersnap Larsen
发明人： Tom Olesen , Martin Christian Valvik , Niels Agersnap Larsen
IPC分类号： G02B21/00 , C12Q1/00 , C12Q1/18 , G02B21/36
CPC分类号： G02B21/0004 , C12Q1/18 , G02B21/365
摘要： The invention relates to a system and a method for determination of a value for at least one parameter describing microbial activity of individual biological organisms in a liquid sample. Images, wherein individual biological organisms may be identified, are combined to provide optical sectionings of the biological organisms and the optical sectionings are analyzed to determine the value for said at least one parameter describing microbial activity of said individual biological organisms in each sample container.

10. 发明授权

US09250176B2 Flexible sample container 有权
标题翻译：灵活的样品容器
公开(公告)号：US09250176B2
公开(公告)日：2016-02-02
申请号：US13582593
申请日：2011-03-02
申请人： Tom Olesen
发明人： Tom Olesen
IPC分类号： G01N1/10 , G01N21/01 , G01N21/00 , G01N15/02 , G01N21/05 , B01L3/00 , G01N21/85 , G01N21/03
CPC分类号： G01N21/05 , B01L3/505 , B01L2300/0832 , B01L2300/0877 , B01L2400/0487 , B01L2400/0655 , G01N21/85 , G01N2021/0346 , G01N2021/0364 , G01N2021/8557
摘要： The invention relates to a system for holding a fluid sample, said system comprising a transparent flexible tube for holding said fluid sample, a tube holder for holding said tube, a first flattening element, and second flattening element, wherein said first flattening element and said second flattening element may be moved relative to each other thereby changing said transparent flexible tube from a first state to a second state, where at least a first cross sectional dimension of said tube is smaller in said second state than in said first state.
摘要翻译：本发明涉及一种用于保持流体样品的系统，所述系统包括用于保持所述流体样品的透明柔性管，用于保持所述管的管保持器，第一平坦化件和第二压平元件，其中所述第一扁平件和所述第二压平元件可以相对于彼此移动，从而将所述透明柔性管从第一状态改变到第二状态，其中所述管的至少第一横截面尺寸在所述第二状态下小于在所述第一状态。

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