专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US09827425B2 Methods and systems of electrode polarity switching in electrical stimulation therapy 有权
公开(公告)号：US09827425B2
公开(公告)日：2017-11-28
申请号：US14475736
申请日：2014-09-03
申请人： EndoStim, Inc.
发明人： Ofer Glasberg , Shai Policker , Virender K. Sharma , Paul V. Goode , Bevil Hogg
IPC分类号： A61N1/36 , A61B5/00
CPC分类号： A61N1/3615 , A61B5/4233 , A61B5/4238 , A61B5/4836 , A61B5/6871 , A61N1/36007 , A61N1/36132 , A61N1/36139 , A61N1/36185
摘要： Methods for electrically stimulating body tissues to improve function or reduce symptoms provide an electrical stimulation system having two or more electrodes that are capable of being switched independently from a hyperpolarizing (depolarizing) state to a hypopolarizing state. Multiple combinations of hyperpolarizing electrodes and hypopolarizing electrodes are created by polarity switching to determine a polarity configuration having the best performance as determined by symptom reporting and clinical diagnostic tests. Polarity switching is triggered manually or is programmed to be switched automatically. Determining the configuration providing electrical stimulation resulting in the greatest benefit allows the system to be operated with one or more electrodes in a hypopolarizing state, thereby reducing energy requirements, tissue tolerance, and tissue fatigue.

2. 发明授权

US09020597B2 Device and implantation system for electrical stimulation of biological systems 有权
标题翻译：用于电刺激生物系统的装置和植入系统
公开(公告)号：US09020597B2
公开(公告)日：2015-04-28
申请号：US13463803
申请日：2012-05-03
申请人： Virender K. Sharma , Edy Sofer , Paul V. Goode , Bevil Hogg , Shai Policker , Matthew Joseph Gani , Jay Miazga , Kaila Raby
发明人： Virender K. Sharma , Edy Sofer , Paul V. Goode , Bevil Hogg , Shai Policker , Matthew Joseph Gani , Jay Miazga , Kaila Raby
IPC分类号： A61N1/36 , A61B5/11 , A61B5/00 , A61B5/053
CPC分类号： A61N1/36007 , A61B5/0538 , A61B5/1116 , A61B5/4836 , A61N1/0517 , A61N1/3606 , A61N1/36139 , A61N1/3614 , A61N1/36171 , A61N1/36175 , A61N1/36178
摘要： The present specification discloses devices and methodologies for the treatment of GERD. Individuals with GERD may be treated by implanting a stimulation device within the patient's lower esophageal sphincter and applying electrical stimulation to the patient's lower esophageal sphincter, in accordance with certain predefined protocols. The presently disclosed devices have a simplified design because they do not require sensing systems capable of sensing when a person is engaged in a wet swallow, have improved energy storage requirements, enable improved LES function while concurrently delivering additional health benefits, and enable improved LES function post stimulation termination.
摘要翻译：本说明书公开了用于治疗GERD的装置和方法。具有GERD的个体可以通过在患者的下食管括约肌内植入刺激装置并根据某些预定义的方案对患者的下食管括约肌施加电刺激来治疗。目前公开的设备具有简化的设计，因为它们不需要能够感测人从事湿吞咽的感测系统，具有改善的能量储存要求，能够改善LES功能，同时提供额外的健康益处，并且能够改善LES功能后刺激终止。

3. 发明授权

US08831729B2 Systems and methods for treating gastroesophageal reflux disease 有权
标题翻译：治疗胃食管反流病的系统和方法
公开(公告)号：US08831729B2
公开(公告)日：2014-09-09
申请号：US13447168
申请日：2012-04-14
申请人： Shai Policker , Virender K. Sharma
发明人： Shai Policker , Virender K. Sharma
IPC分类号： A61N1/36 , A61N1/00 , A61N1/372 , G06F19/00
CPC分类号： A61N1/36007 , A61B17/3468 , A61B17/3478 , A61N1/00 , A61N1/0517 , A61N1/37205 , A61N1/37282 , A61N1/3787 , G06F19/00 , G06F19/34 , G16H15/00 , G16H20/40
摘要： Systems and methods for treating gastroesophageal reflux disease (GERD) includes minimally invasively implanting a stimulating device in a patient's esophagus in the region proximate the lower esophageal sphincter (LES). The patient is provided with a questionnaire related to his disease via an online service. The questionnaire is accessed on a mobile device, such as a cell phone, or on a computer with network access. The data from the sensors and the answers from the questionnaire are analyzed together by a health care provider using the online service. The data and answers are used to program the stimulating device, via the mobile device or computer, to optimize treatment.
摘要翻译：用于治疗胃食管反流病（GERD）的系统和方法包括在邻近下食道括约肌（LES）的区域中最小限度地将刺激装置植入患者食道中。通过在线服务向患者提供与他的疾病相关的调查问卷。问卷在诸如手机的移动设备上或在具有网络访问的计算机上被访问。来自传感器的数据和问卷的答案由医疗保健提供者一起使用在线服务进行分析。数据和答案用于通过移动设备或计算机对刺激装置进行编程，以优化治疗。

4. 发明申请

US20140222106A1 Device and Implantation System for Electrical Stimulation of Biological Systems 审中-公开
标题翻译：用于电刺激生物系统的装置和植入系统
公开(公告)号：US20140222106A1
公开(公告)日：2014-08-07
申请号：US14175927
申请日：2014-02-07
申请人： EndoStim, Inc.
发明人： Virender K. Sharma , Matt Joseph Gani , Paul V. Goode , Bevil Hogg , Jay Miazga , Shai Policker , Kaila Raby
IPC分类号： A61N1/36
CPC分类号： A61N1/36007 , A61B5/14539 , A61B5/6852 , A61B5/6861 , A61B5/687 , A61B2562/0247 , A61N1/0517 , A61N1/3606 , A61N1/36139 , A61N1/36157 , A61N1/36171 , A61N1/36175
摘要： The present specification discloses devices and methodologies for the treatment of GERD. Individuals with GERD may be treated by implanting a stimulation device within the patient's lower esophageal sphincter and applying electrical stimulation to the patient's lower esophageal sphincter, in accordance with certain predefined protocols. The presently disclosed devices have a simplified design because they do not require sensing systems capable of sensing when a person is engaged in a wet swallow and have improved energy storage requirements.
摘要翻译：本说明书公开了用于治疗GERD的装置和方法。具有GERD的个体可以通过在患者的下食管括约肌内植入刺激装置并且根据某些预定义的方案对患者的下食管括约肌施加电刺激来治疗。目前公开的设备具有简化的设计，因为它们不需要能够感测人何时从事湿式吞咽并具有改进的能量存储要求的感测系统。

5. 发明授权

US09381344B2 Systems and methods for treating gastroesophageal reflux disease 有权
标题翻译：治疗胃食管反流病的系统和方法
公开(公告)号：US09381344B2
公开(公告)日：2016-07-05
申请号：US14337006
申请日：2014-07-21
申请人： EndoStim, Inc.
发明人： Virender K Sharma , Shai Policker
IPC分类号： A61N1/36 , A61N1/05 , A61N1/00 , A61N1/372 , G06F19/00
CPC分类号： A61N1/36007 , A61B17/3468 , A61B17/3478 , A61N1/00 , A61N1/0517 , A61N1/37205 , A61N1/37282 , A61N1/3787 , G06F19/00 , G06F19/34 , G16H15/00 , G16H20/40
摘要： Systems and methods for treating gastroesophageal reflux disease (GERD) includes minimally invasively implanting a stimulating device in a patient's esophagus in the region proximate the lower esophageal sphincter (LES). The patient is provided with a questionnaire related to his disease via an online service. The questionnaire is accessed on a mobile device, such as a cell phone, or on a computer with network access. The data from the sensors and the answers from the questionnaire are analyzed together by a health care provider using the online service. The data and answers are used to program the stimulating device, via the mobile device or computer, to optimize treatment.
摘要翻译：用于治疗胃食管反流病（GERD）的系统和方法包括在邻近下食道括约肌（LES）的区域中最小限度地将刺激装置植入患者食道中。通过在线服务向患者提供与他的疾病相关的调查问卷。问卷在诸如手机的移动设备上或在具有网络访问的计算机上被访问。来自传感器的数据和问卷的答案由医疗保健提供者一起使用在线服务进行分析。数据和答案用于通过移动设备或计算机对刺激装置进行编程，以优化治疗。

6. 发明授权

US09037245B2 Endoscopic lead implantation method 有权
标题翻译：内镜引线植入法
公开(公告)号：US09037245B2
公开(公告)日：2015-05-19
申请号：US13602184
申请日：2012-09-02
申请人： Virender K. Sharma , Shai Policker , Paul V. Goode , Bevil Hogg
发明人： Virender K. Sharma , Shai Policker , Paul V. Goode , Bevil Hogg
IPC分类号： A61B1/00 , A61B1/273 , A61B5/06 , A61B6/12 , A61B7/00 , A61B8/00 , A61N1/05
CPC分类号： A61N1/0509 , A61B1/00087 , A61B1/2733 , A61B5/06 , A61B5/064 , A61B6/12 , A61B7/00 , A61B8/00 , A61B8/0841 , A61N1/0517
摘要： A method of implanting electrically conductive leads in the gastrointestinal musculature for stimulation of target tissues involves an endoscopic approach through the esophagus. An endoscope is inserted into the esophagus of a patient. The mucosal surface of the anterior esophagus is punctured in the region encompassing the lower esophageal sphincter (LES). A tunnel is created through the submucosa and exits at the muscularis propria, adventitia, or serosal side of the stomach. The lead is navigated further to the anterior abdominal wall. A first end of the lead remains within the gastrointestinal musculature while a second end of the lead is positioned just outside the anterior abdominal wall. The first end of the lead comprises at least one electrode. An implantable pulse generator (IPG) is implanted and operably connected to the second end of the lead to provide electrical stimulation to target tissues.
摘要翻译：在胃肠肌肉组织中植入导电引线以刺激靶组织的方法涉及通过食道的内窥镜方法。将内窥镜插入患者的食道中。在食管下括约肌（LES）的区域内，前食管的粘膜表面被穿刺。通过粘膜下层产生隧道，并在胃的内固定层，外膜或浆膜侧退出。导线进一步前进到前腹壁。铅的第一端保持在胃肠肌肉组织内，而引线的第二端位于前腹壁正前方。引线的第一端包括至少一个电极。植入式脉冲发生器（IPG）被植入并且可操作地连接到引线的第二端以向靶组织提供电刺激。

7. 发明申请

US20140249594A1 Device and Implantation System for Electrical Stimulation of Biological Systems 有权
公开(公告)号：US20140249594A1
公开(公告)日：2014-09-04
申请号：US14201645
申请日：2014-03-07
申请人： EndoStim, Inc.
发明人： Virender K. Sharma , Matt Joseph Gani , Paul V. Goode , Bevil Hogg , Jay Miazga , Shai Policker , Kaila Raby
IPC分类号： A61N1/36 , A61N1/372
CPC分类号： A61B5/0031 , A61B5/037 , A61B5/0538 , A61B5/1116 , A61B5/14539 , A61B5/4211 , A61B5/4836 , A61N1/36007 , A61N1/3606 , A61N1/36139 , A61N1/36157 , A61N1/36171 , A61N1/36175 , A61N1/37235
摘要： The present specification discloses devices and methodologies for the treatment of transient lower esophageal sphincter relaxations (tLESRs). Individuals with tLESRs may be treated by implanting a stimulation device within the patient's lower esophageal sphincter and applying electrical stimulation to the patient's lower esophageal sphincter, in accordance with certain predefined protocols. The presently disclosed devices have a simplified design because they do not require sensing systems capable of sensing when a person is engaged in a wet swallow and have improved energy storage requirements.

8. 发明申请

US20140243593A1 Implantable Electrical Stimulation Leads 有权
标题翻译：可植入电刺激线索
公开(公告)号：US20140243593A1
公开(公告)日：2014-08-28
申请号：US14191085
申请日：2014-02-26
申请人： EndoStim, Inc.
发明人： Paul V. Goode , Ofer Glasberg , Virender K. Sharma
IPC分类号： A61N1/05 , A61B1/018 , A61F5/00
CPC分类号： A61N1/0509 , A61B1/00082 , A61B1/00087 , A61B18/082 , A61B2017/0034 , A61B2018/00595 , A61F5/0026 , A61N1/36007
摘要： An implantable electrical stimulation lead for the treatment of biological conditions includes a lead body with an electrical connector at one end and a pair of monopolar branches at the other end. The lead body has a length ranging from 390 mm to 490 mm to allow for implantation from an incision site further removed from the final positioning site of the electrodes. The branches have lengths ranging from 50 mm to 120 mm for the both branches. These lengths facilitate successful laparoscopic implantation at sites with confined anatomy, such as, near the gastroesophageal junction. The branches include needles and sutures at their ends for suturing anchors positioned on the branches to surrounding tissue. The needles have curves designed to facilitate maneuvering in confined anatomy. A separate lead includes a suture loop connecting the ends of the first and second branches rather than needles. The loop is used to pull the lead through the working channel of an endoscope. The anchors on the lead are porous and allow for the ingrowth of surrounding tissue for fixing the branches in place.
摘要翻译：用于治疗生物条件的可植入电刺激引线包括在一端具有电连接器的引线体和另一端的一对单极支路。引线体的长度范围为390mm至490mm，以允许从电极的最终定位位置进一步移除的切割部位进行植入。这两个分支的分支长度范围从50毫米到120毫米。这些长度有助于成功的腹腔镜植入在具有狭窄解剖结构的位置，例如靠近胃食管交界处。分支包括在其端部处的针和缝合线，用于缝合位于分支上的锚定物到周围的组织。针头具有设计用于在狭窄的解剖结构中操纵的曲线。单独的引线包括连接第一和第二分支的端部而不是针的缝合线环。该回路用于将引线拉过内窥镜的工作通道。引线上的锚点是多孔的，并允许周围组织的向内生长用于固定分支到位。

9. 发明授权

US08798753B2 Device and implantation system for electrical stimulation of biological systems 有权
标题翻译：用于电刺激生物系统的装置和植入系统
公开(公告)号：US08798753B2
公开(公告)日：2014-08-05
申请号：US13934040
申请日：2013-07-02
申请人： Endostim, Inc.
发明人： Virender K. Sharma
IPC分类号： A61N1/05 , A61B5/00 , A61N1/36
CPC分类号： A61B5/6879 , A61N1/05 , A61N1/0502 , A61N1/0551 , A61N1/0558 , A61N1/36007
摘要： An implantable stimulation device for use in stimulation based treatments for diseases such as GERD or obesity is described. The device is provided with an anchoring unit which upon deployment assumes a shape optimized for the site of deployment. Sensing electrodes and stimulating electrodes in the device are also designed to assume a suitable shape upon deployment. A novel catheter is also provided for easy and expeditious deployment of the device.
摘要翻译：描述了用于基于刺激的治疗用于诸如GERD或肥胖症的疾病的植入式刺激装置。该装置设置有锚定单元，其在部署时采取针对部署现场优化的形状。设备中的感应电极和刺激电极也被设计成在部署时呈现合适的形状。还提供了一种新颖的导管，用于容易且快速地部署该装置。

10. 发明申请

US20140018657A1 Device and Implantation System for Electrical Stimulation of Biological Systems 有权
标题翻译：用于电刺激生物系统的装置和植入系统
公开(公告)号：US20140018657A1
公开(公告)日：2014-01-16
申请号：US13934040
申请日：2013-07-02
申请人： Endostim, Inc.
发明人： Virender K. Sharma
IPC分类号： A61B5/00 , A61N1/05
CPC分类号： A61B5/6879 , A61N1/05 , A61N1/0502 , A61N1/0551 , A61N1/0558 , A61N1/36007
摘要： An implantable stimulation device for use in stimulation based treatments for diseases such as GERD or obesity is described. The device is provided with an anchoring unit which upon deployment assumes a shape optimized for the site of deployment. Sensing electrodes and stimulating electrodes in the device are also designed to assume a suitable shape upon deployment. A novel catheter is also provided for easy and expeditious deployment of the device.
摘要翻译：描述了用于基于刺激的治疗用于诸如GERD或肥胖症的疾病的可植入刺激装置。该装置设置有锚定单元，其在部署时采取针对部署现场优化的形状。设备中的感应电极和刺激电极也被设计成在部署时呈现合适的形状。还提供了一种新颖的导管，用于容易且快速地部署该装置。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式