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1. 发明申请

US20160299469A1 MULTIPLE LAMINAR FLOW-BASED PARTICLE AND CELLULAR SEPARATION WITH LASER STEERING 审中-公开
标题翻译：多层次流动粒子和细胞分离与激光转向
公开(公告)号：US20160299469A1
公开(公告)日：2016-10-13
申请号：US15099891
申请日：2016-04-15
申请人： PREMIUM GENETICS (UK) LTD.
发明人： Daniel Mueth , Joseph Plewa , Jessica Shireman , Amy Anderson , Lewis Gruber , Neil Rosenbaum
IPC分类号： G03H1/00 , G01N33/50 , G21K5/08 , G01N33/487
CPC分类号： G03H1/0005 , A61L2/08 , B01D21/0009 , B01D21/01 , B01D21/262 , B01L3/502761 , B01L2200/0652 , B01L2200/0668 , B01L2300/0864 , B01L2400/0454 , B03C1/00 , B03C1/002 , B03C1/288 , B03C5/005 , B04B13/00 , G01N15/0205 , G01N21/6486 , G01N27/447 , G01N27/44756 , G01N33/487 , G01N33/5091 , G01N2015/0053 , G01N2201/061 , G01N2458/00 , G02B21/32 , G03H1/08 , G03H1/2294 , G03H2001/0077 , G03H2001/085 , G03H2225/32 , G21K5/08 , H05H3/04
摘要： The invention provides a method, apparatus and system for separating blood and other types of cellular components, and can be combined with holographic optical trapping manipulation or other forms of optical tweezing. One of the exemplary methods includes providing a first flow having a plurality of blood components; providing a second flow; contacting the first flow with the second flow to provide a first separation region; and differentially sedimenting a first blood cellular component of the plurality of blood components into the second flow while concurrently maintaining a second blood cellular component of the plurality of blood components in the first flow. The second flow having the first blood cellular component is then differentially removed from the first flow having the second blood cellular component. Holographic optical traps may also be utilized in conjunction with the various flows to move selected components from one flow to another, as part of or in addition to a separation stage.
摘要翻译：本发明提供了一种用于分离血液和其他类型的细胞组分的方法，装置和系统，并且可以与全息光学捕获操作或其他形式的光学镊子组合。示例性方法之一包括提供具有多个血液成分的第一流; 提供第二流; 使第一流与第二流接触以提供第一分离区; 以及将所述多个血液成分的第一血细胞成分差异沉积到所述第二流中，同时在所述第一流中同时维持所述多个血液成分的第二血细胞成分。然后，具有第一血细胞成分的第二流与具有第二血细胞成分的第一流有差别地移除。全息光学捕集器也可以与各种流动结合使用，以将选定的组分从一个流移动到另一个流，作为分离阶段的一部分或除了分离阶段之外。

2. 发明申请

US20160299120A1 MULTIPLE LAMINAR FLOW-BASED PARTICLE AND CELLULAR SEPARATION WITH LASER STEERING 审中-公开
公开(公告)号：US20160299120A1
公开(公告)日：2016-10-13
申请号：US15099900
申请日：2016-04-15
申请人： PREMIUM GENETICS (UK) LTD.
发明人： Daniel Mueth , Joseph Plewa , Jessica Shireman , Amy Anderson , Lewis Gruber , Neil Rosenbaum
IPC分类号： G01N33/487 , H05H3/04 , G03H1/00 , G01N21/64 , G02B21/32
CPC分类号： G03H1/0005 , A61L2/08 , B01D21/0009 , B01D21/01 , B01D21/262 , B01L3/502761 , B01L2200/0652 , B01L2200/0668 , B01L2300/0864 , B01L2400/0454 , B03C1/00 , B03C1/002 , B03C1/288 , B03C5/005 , B04B13/00 , G01N15/0205 , G01N21/6486 , G01N27/447 , G01N27/44756 , G01N33/487 , G01N33/5091 , G01N2015/0053 , G01N2201/061 , G01N2458/00 , G02B21/32 , G03H1/08 , G03H1/2294 , G03H2001/0077 , G03H2001/085 , G03H2225/32 , G21K5/08 , H05H3/04
摘要： The invention provides a method, apparatus and system for separating blood and other types of cellular components, and can be combined with holographic optical trapping manipulation or other forms of optical tweezing. One of the exemplary methods includes providing a first flow having a plurality of blood components; providing a second flow; contacting the first flow with the second flow to provide a first separation region; and differentially sedimenting a first blood cellular component of the plurality of blood components into the second flow while concurrently maintaining a second blood cellular component of the plurality of blood components in the first flow. The second flow having the first blood cellular component is then differentially removed from the first flow having the second blood cellular component. Holographic optical traps may also be utilized in conjunction with the various flows to move selected components from one flow to another, as part of or in addition to a separation stage.

3. 发明申请

US20160047777A1 MULTIPLE LAMINAR FLOW-BASED PARTICLE AND CELLULAR SEPARATION WITH LASER STEERING 审中-公开
公开(公告)号：US20160047777A1
公开(公告)日：2016-02-18
申请号：US14829993
申请日：2015-08-19
申请人： PREMIUM GENETICS (UK) LTD.
发明人： Daniel MUETH , Joseph PLEWA , Jessica SHIREMAN , Amy ANDERSON , Lewis GRUBER , Neil ROSENBAUM
IPC分类号： G01N27/447 , A61L2/08 , B01D21/26 , B04B13/00 , G01N33/487 , B03C1/00
CPC分类号： G03H1/0005 , A61L2/08 , B01D21/0009 , B01D21/01 , B01D21/262 , B01L3/502761 , B01L2200/0652 , B01L2200/0668 , B01L2300/0864 , B01L2400/0454 , B03C1/00 , B03C1/002 , B03C1/288 , B03C5/005 , B04B13/00 , G01N15/0205 , G01N21/6486 , G01N27/447 , G01N27/44756 , G01N33/487 , G01N33/5091 , G01N2015/0053 , G01N2201/061 , G01N2458/00 , G02B21/32 , G03H1/08 , G03H1/2294 , G03H2001/0077 , G03H2001/085 , G03H2225/32 , G21K5/08 , H05H3/04
摘要： The invention provides a method, apparatus and system for separating blood and other types of cellular components, and can be combined with holographic optical trapping manipulation or other forms of optical tweezing. One of the exemplary methods includes providing a first flow having a plurality of blood components; providing a second flow; contacting the first flow with the second flow to provide a first separation region; and differentially sedimenting a first blood cellular component of the plurality of blood components into the second flow while concurrently maintaining a second blood cellular component of the plurality of blood components in the first flow. The second flow having the first blood cellular component is then differentially removed from the first flow having the second blood cellular component. Holographic optical traps may also be utilized in conjunction with the various flows to move selected components from one flow to another, as part of or in addition to a separation stage.

4. 发明授权

US09254493B2 Oxygen-enriched air producing device and oxygen-enriched air producing method 有权
标题翻译：富氧空气生产装置和富氧空气生产方法
公开(公告)号：US09254493B2
公开(公告)日：2016-02-09
申请号：US14003700
申请日：2012-05-08
申请人： Kenichi Inoue , Takashi Hase , Shingo Kasai
发明人： Kenichi Inoue , Takashi Hase , Shingo Kasai
IPC分类号： B03C1/00 , B01D53/22 , B01D57/02 , C01B13/02
CPC分类号： B03C1/00 , B01D53/22 , B01D57/02 , C01B13/0248
摘要： The invention is characterized in: forming a magnetic field inside a flow channel tube, the tube wall of which is formed from a material that is nonmagnetic and which, when the pressure outside the flow channel tube is lower than the pressure inside the flow channel tube, passes a portion of the air flowing inside the tube through the tube wall and discharges same to the outside thereof; supplying air to the flow channel tube so that at least a region of laminar flow is formed inside the flow channel tube; and reducing the pressure outside the flow channel tube to a prescribed pressure.
摘要翻译：本发明的特征在于：在流道管内形成磁场，其管壁由非磁性的材料形成，当流道管外部的压力低于流道管内的压力时使流过管内的空气的一部分通过管壁，并将其排出到其外部; 向所述流路管供给空气，使得在所述流路管内形成至少一层层流区域; 并将流道管外的压力降低到规定的压力。

5. 发明授权

US09140690B2 Method of identifying components in a fluid mixture 有权
标题翻译：识别流体混合物中的组分的方法
公开(公告)号：US09140690B2
公开(公告)日：2015-09-22
申请号：US14663012
申请日：2015-03-19
申请人： PREMIUM GENETICS (UK) LTD.
发明人： Daniel Mueth , Joseph Plewa , Jessica Shireman , Amy Anderson , Lewis Gruber , Neil Rosenbaum
IPC分类号： G01N33/50 , G02B21/32 , H05H3/04 , B01D21/01 , G01N33/487 , G01N21/64 , G03H1/08 , G03H1/22 , G03H1/00
CPC分类号： G03H1/0005 , A61L2/08 , B01D21/0009 , B01D21/01 , B01D21/262 , B01L3/502761 , B01L2200/0652 , B01L2200/0668 , B01L2300/0864 , B01L2400/0454 , B03C1/00 , B03C1/002 , B03C1/288 , B03C5/005 , B04B13/00 , G01N15/0205 , G01N21/6486 , G01N27/447 , G01N27/44756 , G01N33/487 , G01N33/5091 , G01N2015/0053 , G01N2201/061 , G01N2458/00 , G02B21/32 , G03H1/08 , G03H1/2294 , G03H2001/0077 , G03H2001/085 , G03H2225/32 , G21K5/08 , H05H3/04
摘要： A method of identifying at least one component from a plurality of components in a fluid mixture introduced into a flow apparatus, includes: introducing a first flow into a first input channel in the apparatus which contains the fluid mixture; introducing additional flows of buffer solution into a plurality of buffer input channels in the apparatus, the plurality of buffer channels which are disposed on either side of the first input channel; wherein the first flow and additional flows have a flow direction along a length of the apparatus; identifying selected components of the plurality of components using a detector apparatus; emitting a light beam from a laser which damages or kills selected components of the plurality of components; receiving the first flow and the additional flows in at least one channel disposed at the other end of the apparatus, after operation of the light beam on the selected components.
摘要翻译：一种从引入到流动装置中的流体混合物中的多个部件中鉴定至少一个部件的方法，包括：将第一流引入到包含流体混合物的装置中的第一输入通道中; 将附加的缓冲溶液流引入所述装置中的多个缓冲器输入通道中，所述多个缓冲通道设置在所述第一输入通道的任一侧上; 其中所述第一流和附加流具有沿所述装置的长度的流动方向; 使用检测器装置识别所述多个部件中的选定部件; 发射来自激光器的光束，其损坏或杀死所述多个部件中的所选部件; 在所选择的部件上操作光束之后，在设置在设备的另一端的至少一个通道中接收第一流和附加流。

6. 发明申请

US20150209798A1 METHOD AND SYSTEM FOR PROCESSING SLAG MATERIAL 有权
标题翻译：用于加工滑石材料的方法和系统
公开(公告)号：US20150209798A1
公开(公告)日：2015-07-30
申请号：US14678465
申请日：2015-04-03
申请人： MID-AMERICAN GUNITE, INC. DBA MID-AMERICAN GROUP
发明人： Donald E. Keaton , Keith P. Masserant , Lawrence I. Masserant
IPC分类号： B03C1/30 , B02C23/20 , B03C1/005 , B02C23/14 , C22B7/00 , C22B7/04
CPC分类号： B03C1/30 , B02C23/14 , B02C23/20 , B03B9/04 , B03C1/00 , B03C1/005 , B03C2201/20 , B22F9/04 , C21B3/06 , C22B7/005 , C22B7/04 , C22B9/14 , Y02P10/212 , Y02W30/543
摘要： A method and system is used to process slag material to yield by-products including a finished iron rich product and a finished low iron fines product. The by-products may include a finished high iron product and a finished medium iron product. The method and system include size classifying the material into a plurality of sized groups prior to using magnetic separation to separate at least one of the sized groups into two portions having differing magnetic susceptibilities. The method and system may include more than one phase of size classifying the material into a plurality of sized groups and using magnetic separation to separate at least one of the sized groups into portions, where the average size of the material remaining after one phase is reduced prior to the subsequent phase.
摘要翻译：一种方法和系统用于处理炉渣材料以产生副产物，包括成品铁富产品和成品低铁粉产品。副产物可以包括成品高铁产品和成品中铁产品。该方法和系统包括在使用磁分离之前将材料分类成多个尺寸的组，以将至少一个尺寸组分成具有不同磁化率的两个部分。该方法和系统可以包括多于一个阶段的尺寸将材料分类成多个尺寸的组，并且使用磁分离将至少一个尺寸的组分离成部分，其中在一相之后剩余的材料的平均尺寸减小在之后的阶段。

7. 发明授权

US08653442B2 Multiple laminar flow-based particle and cellular separation with laser steering 有权
标题翻译：多层次流动粒子与细胞分离与激光转向
公开(公告)号：US08653442B2
公开(公告)日：2014-02-18
申请号：US13412969
申请日：2012-03-06
申请人： Daniel Mueth , Joseph Plewa , Jessica Shireman , Amy Anderson , Lewis Gruber , Neil Harris Rosenbaum
发明人： Daniel Mueth , Joseph Plewa , Jessica Shireman , Amy Anderson , Lewis Gruber , Neil Harris Rosenbaum
IPC分类号： B01D21/01
CPC分类号： G03H1/0005 , A61L2/08 , B01D21/0009 , B01D21/01 , B01D21/262 , B01L3/502761 , B01L2200/0652 , B01L2200/0668 , B01L2300/0864 , B01L2400/0454 , B03C1/00 , B03C1/002 , B03C1/288 , B03C5/005 , B04B13/00 , G01N15/0205 , G01N21/6486 , G01N27/447 , G01N27/44756 , G01N33/487 , G01N33/5091 , G01N2015/0053 , G01N2201/061 , G01N2458/00 , G02B21/32 , G03H1/08 , G03H1/2294 , G03H2001/0077 , G03H2001/085 , G03H2225/32 , G21K5/08 , H05H3/04
摘要： The invention provides a method, apparatus and system for separating cellular components, and can be combined with holographic optical trapping manipulation or other forms of optical tweezing. One exemplary method includes providing a first flow having a plurality of components; providing a second flow; contacting the first flow with the second flow to provide a first separation region; and differentially sedimenting a first cellular component of the plurality of components into the second flow while concurrently maintaining a second cellular component of the plurality of components in the first flow. The second flow having the first cellular component is then differentially removed from the first flow having the second cellular component. Holographic optical traps may also be utilized in conjunction with the various flows to move selected components from one flow to another, as part of or in addition to a separation stage.
摘要翻译：本发明提供一种用于分离细胞成分的方法，装置和系统，并且可以与全息光学捕获操作或其他形式的光学镊子组合。一个示例性方法包括提供具有多个部件的第一流; 提供第二流; 使第一流与第二流接触以提供第一分离区; 以及将所述多个部件的第一细胞组分差异沉积到所述第二流中，同时将所述多个组分的第二细胞组分保持在所述第一流中。然后将具有第一细胞组分的第二流与具有第二细胞组分的第一流差异地去除。全息光学捕集器也可以与各种流动结合使用，以将选定的组分从一个流移动到另一个流，作为分离阶段的一部分或除了分离阶段之外。

8. 发明申请

US20130344237A1 GRAPHENE NANOCOMPOSITES 有权
标题翻译：石墨纳米复合材料
公开(公告)号：US20130344237A1
公开(公告)日：2013-12-26
申请号：US13680464
申请日：2012-11-19
申请人： Lamar University
发明人： ZHANHU GUO
IPC分类号： B03C1/00
CPC分类号： B03C1/00 , B03C1/01 , H01F1/42
摘要： A nanocomposite material for use as an electromagnetic wave or radio frequency absorber or as a filter to trap or remove heavy metals. The nanocomposite material may be made with a one-pot synthesis, or thermodecomposition process, of magnetic graphene nanocomposites decorated with core-double-shell nanoparticles, wherein the double shell iron nanoparticles may comprise a crystalline iron core, an inner iron oxide layer around the crystalline iron core, and an outermost amorphous Si—S—O compound shell around the iron oxide layer.
摘要翻译：用作电磁波或射频吸收器的纳米复合材料或用作捕集或去除重金属的过滤器。纳米复合材料可以用一体式合成或热分解方法制备，用核 - 双壳纳米颗粒装饰的磁性石墨烯纳米复合材料，其中双壳铁纳米颗粒可以包含结晶铁芯，围绕结晶铁芯和氧化铁层周围的最外层的非晶Si-SO化合物壳。

9. 发明申请

US20130284654A1 Magnetic Separation System Comprising Flexible Magnetic Pins 审中-公开
标题翻译：磁分离系统包括柔性磁销
公开(公告)号：US20130284654A1
公开(公告)日：2013-10-31
申请号：US13932970
申请日：2013-07-01
申请人： Roche Molecular Systems, Inc.
发明人： Thomas Meyer
IPC分类号： B03C1/00
CPC分类号： B03C1/00 , B03C1/288 , B03C2201/26 , G01N35/0098 , G01N35/028 , Y10T436/25375
摘要： A magnetic separation plate for use in methods employing magnetic particles, said magnetic separation plate comprising a support plate and magnetic pins in a predetermined geometrical arrangement, said magnetic pins having a fastening portion, an intermediate portion and a separation portion and being fastened to said support plate at their fastening portion, wherein said magnetic pins are individually displaceable at their separation portion. The invention further provides a method for the separation of magnetic particles using the separation plate.
摘要翻译：一种用于使用磁性颗粒的方法的磁分离板，所述磁分离板包括支撑板和预定几何布置的磁性销，所述磁性销具有紧固部分，中间部分和分离部分，并且紧固到所述支撑件在其紧固部分处的板，其中所述磁性销在其分离部分处可单独移位。本发明还提供了使用分离板分离磁性颗粒的方法。

10. 发明申请

US20130240415A1 METHOD AND SYSTEM FOR PROCESSING SLAG MATERIAL 有权
公开(公告)号：US20130240415A1
公开(公告)日：2013-09-19
申请号：US13757147
申请日：2013-02-01
申请人： MID-AMERICAN GUNITE, INC.
发明人： Donald E. Keaton , Keith P. Masserant , Lawrence I. Masserant
IPC分类号： B03C1/00
CPC分类号： B03C1/30 , B02C23/14 , B02C23/20 , B03B9/04 , B03C1/00 , B03C1/005 , B03C2201/20 , B22F9/04 , C21B3/06 , C22B7/005 , C22B7/04 , C22B9/14 , Y02P10/212 , Y02W30/543
摘要： A method and system is used to process slag material to yield by-products including a finished iron rich product and a finished low iron fines product. The by-products may include a finished high iron product and a finished medium iron product. The method and system include size classifying the material into a plurality of sized groups prior to using magnetic separation to separate at least one of the sized groups into two portions having differing magnetic susceptibilities. The method and system may include more than one phase of size classifying the material into a plurality of sized groups and using magnetic separation to separate at least one of the sized groups into portions, where the average size of the material remaining after one phase is reduced prior to the subsequent phase.

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