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    • 6. 发明申请
    • Microvesicles
    • 微泡
    • US20160032322A1
    • 2016-02-04
    • US14789121
    • 2015-07-01
    • Lydac Neuroscience Limited
    • Stephen Ray
    • C12P1/00C12N5/071
    • C12P1/00A61K8/981A61K35/28A61K2800/10A61Q19/00C12N5/0602C12N2506/1353C12N2523/00
    • A method of producing a population of differentiated cells comprising: a) inducing differentiation in a first population of cells by applying an inducer to said cells, b) harvesting microvesicles produced from first population of cells, and c) inducing differentiation in a second population of cells by applying said microvesicles or a derivative thereof to said second population of cells wherein, said first population of cells is autologous to said second population of cells and wherein the inducer applied to said first population of cells is not present in said second population of cells or is only present in trace amounts. Also related methods of producing microvesicles, methods of medical and/or cosmetic treatment and related products and uses.
    • 一种产生分化细胞群体的方法,包括:a)通过向所述细胞施加诱导剂来诱导第一群细胞中的分化,b)收获由第一群细胞产生的微泡,以及c)在第二群体中诱导分化 通过将所述微泡或其衍生物施用于所述第二细胞群,其中所述第一细胞群与所述第二细胞群自体,并且其中应用于所述第一细胞群的诱导物不存在于所述第二细胞群中 或仅存在痕量。 还涉及生产微泡的方法,医疗和/或美容治疗方法以及相关产品和用途。