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    • 10. 发明授权
    • Fabrication of three dimensional aligned nanofiber array
    • 三维排列纳米纤维阵列的制作
    • US08580181B1
    • 2013-11-12
    • US12896268
    • 2010-10-01
    • Vince BeachleyXuejun Wen
    • Vince BeachleyXuejun Wen
    • B29C47/00
    • D01D5/0076D01D7/00D04H1/4382D04H1/728D04H3/016D04H3/033D04H3/05D04H3/16
    • Disclosed are methods of forming three dimensional arrays of aligned nanofibers in an open, loose structure of any desired depth. The arrays are formed according to an electrospinning process utilizing two parallel conducting plates to align the fibers and rotating tracks to distribute the fibers throughout the array. Arrays can be used as formed, for instance in tissue engineering applications as three dimensional scaffolding constructs. As-formed arrays can be combined with other materials to form a composite 3-D structure. For instance, composite polymeric materials can be electrospun to form composite nanofibers within the array. Multiple polymeric materials can be electrospun at different areas of the array to form a composite array including materially different nanofibers throughout the array. The arrays can be loaded with other fibrous or non-fibrous materials to form a composite array. Arrays can also be rolled to form a uniaxial fiber bundle.
    • 公开了以任何所需深度的开放松散结构形成排列的纳米纤维的三维阵列的方法。 阵列根据电纺丝工艺形成,利用两个平行的导电板来对准纤维和旋转的轨道以将纤维分布在整个阵列中。 阵列可用于形成,例如在组织工程应用中作为三维脚手架构造。 形成阵列可以与其他材料组合以形成复合3-D结构。 例如,复合聚合物材料可以电纺丝以在阵列内形成复合纳米纤维。 多个聚合物材料可以在阵列的不同区域静电纺丝以形成整个阵列中包括物理上不同的纳米纤维的复合阵列。 阵列可以装载其他纤维或非纤维材料以形成复合阵列。 也可以将阵列轧制以形成单轴纤维束。