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1. 发明授权

US09895480B2 Dialysis system 有权
公开(公告)号：US09895480B2
公开(公告)日：2018-02-20
申请号：US14309494
申请日：2014-06-19
申请人： State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University , Home Dialysis Plus, Ltd.
发明人： Julie S. Wrazel , James R. Curtis , Ladislaus Nonn , Richard B. Peterson , Hailei Wang , Robbie Ingram-Goble , Luke W. Fisher , Anna E. Garrison , M. Kevin Drost , Goran Jovanovic , Richard Todd Miller , Bruce W. Johnson , Alana Anderson , Eric K. Anderson
IPC分类号： A61M1/16 , B01D63/08 , C02F1/02 , C02F9/00 , F24H1/12 , A61M1/14 , C02F1/44 , C02F1/20 , C02F1/28 , C02F103/02 , F28F3/08 , F28D7/12 , F24H9/00 , F28D21/00
CPC分类号： A61M1/1686 , A61M1/14 , A61M1/16 , A61M1/1656 , A61M1/1662 , A61M1/1666 , A61M2205/0244 , B01D63/085 , B01D2313/08 , C02F1/02 , C02F1/20 , C02F1/283 , C02F1/44 , C02F1/441 , C02F1/444 , C02F9/005 , C02F2103/026 , C02F2209/03 , C02F2209/05 , C02F2303/04 , F24H1/121 , F24H9/0021 , F28D7/12 , F28D2021/005 , F28F3/08 , F28F2260/02 , Y10T29/494
摘要： A dialysis system includes a filtration system capable of filtering a water stream, a water purification system capable of purifying said water stream in a non-batch process, a mixing system capable of producing a stream of dialysate from mixing one or more dialysate components with the water stream in a non-batch process, and a dialyzer system. The dialyzer may be a microfluidic dialyzer capable of being fluidly coupled to the stream of dialysate and a blood stream.

2. 发明授权

US09630130B2 Multi-segmented tube sheet 有权
公开(公告)号：US09630130B2
公开(公告)日：2017-04-25
申请号：US15050934
申请日：2016-02-23
申请人： Paul F. Nehlen, III
发明人： Paul F. Nehlen, III
IPC分类号： B01D35/30 , B01D35/06 , B01D29/01 , C02F1/32 , F28F9/02 , F28F19/01 , F28F27/00 , C02F1/68 , F16L9/00 , B01D15/36 , F28F9/06 , F28F9/16 , F28D21/00
CPC分类号： B01D35/30 , A61M1/0259 , A61M5/44 , B01D15/361 , B01D29/018 , B01D29/56 , B01D35/06 , B01D2201/0446 , B01D2313/025 , C02F1/325 , C02F1/685 , F16L9/00 , F28D2021/005 , F28F9/0221 , F28F9/0229 , F28F9/06 , F28F9/16 , F28F19/01 , F28F27/00
摘要： A method of manufacturing a tube sheet by forming a plurality of separate thin tube sheet segments; forming multiple holes in each sheet in a predetermined pattern, each hole for accommodating a tube sheet filter tube; aligning all of the plurality of tube sheet segments so that the hole pattern of each sheet aligns with the hole pattern in all other sheets of the plurality of tube sheet segments; and securing all of the tube sheet segments together to form a unitary tube sheet. A tube sheet construction that includes a plurality of separate thin tube sheet segments, multiple holes being provided in each sheet in a predetermined pattern, each hole for accommodating a tube sheet filter tube, all of the tube sheet segments being aligning so that the hole pattern of each sheet aligns, and fasteners for securing all of the tube sheet segments together. A media layer is provided between adjacent sheet segments.

3. 发明申请

US20160271342A1 FLUID WARMING SYSTEM 有权
标题翻译：流体保温系统
公开(公告)号：US20160271342A1
公开(公告)日：2016-09-22
申请号：US15070144
申请日：2016-03-15
申请人： THE SURGICAL COMPANY INTERNATIONAL B.V.
发明人： Joris BRONKHORST , Jeroen Hermanus Johannes WIJLENS
IPC分类号： A61M5/44 , F24H9/02 , F28F13/00 , F24H1/14
CPC分类号： A61M5/44 , A61F7/00 , A61F2007/126 , A61M5/445 , A61M2205/121 , A61M2205/127 , A61M2205/3368 , A61M2205/3653 , F24H1/142 , F24H9/02 , F24H9/2028 , F28D2021/005 , F28F3/12 , F28F13/00 , F28F2013/008 , H05B3/20 , H05B3/58 , H05B2203/021
摘要： There is disclosed a heater unit (1600) for conductively heating a removable heat exchanger unit (1602) via a heat transfer surface of the heat exchanger unit, the heater unit comprising: a body portion (1610) for receiving the heat exchanger unit (1602); a flexible heating element (1604) which, in use, makes thermal contact with the heat transfer surface of the heat exchanger unit; a compressible portion (1606) disposed on the distal side of the flexible heating element (1604) relative to the heat exchanger unit (1602) when received; and a biasing arrangement (1608) operable, in use, to distribute a transverse compression force across the arrangement formed from the compressible portion (1606), the heating element (1604) and the heat exchanger unit (1602), whereby the compression force causes the heating element (1604) to be urged towards the heat transfer surface of the heat exchanger unit (1602) and the compressible portion, in conjunction with the compression force, causes the heating element (1604) to conform more closely to the shape of the heat transfer surface.
摘要翻译：公开了一种用于经由热交换器单元的传热表面导电地加热可移除热交换器单元（1602）的加热器单元（1600），加热器单元包括：主体部分（1610），用于接收热交换器单元）; 柔性加热元件（1604），其在使用中与热交换器单元的传热表面热接触; 当接收时相对于热交换器单元（1602）设置在柔性加热元件（1604）的远侧上的可压缩部分（1606）以及偏压装置（1608），其在使用中可以横跨由可压缩部分（1606），加热元件（1604）和热交换器单元（1602）形成的布置分布横向压缩力，由此压缩力与热交换器单元（1602）和可压缩部分一起受压的加热元件（1604）与压缩力一起被迫使加热元件（1604）更接近于传热面。

4. 发明申请

US20160166958A1 MULTI-SEGMENTED TUBE SHEET 有权
公开(公告)号：US20160166958A1
公开(公告)日：2016-06-16
申请号：US15050934
申请日：2016-02-23
申请人： Paul F. Nehlen, III
发明人： Paul F. Nehlen, III
IPC分类号： B01D35/30 , C02F1/32 , B01D35/06 , C02F1/68 , B01D29/01 , B01D15/36
CPC分类号： B01D35/30 , A61M1/0259 , A61M5/44 , B01D15/361 , B01D29/018 , B01D29/56 , B01D35/06 , B01D2201/0446 , B01D2313/025 , C02F1/325 , C02F1/685 , F16L9/00 , F28D2021/005 , F28F9/0221 , F28F9/0229 , F28F9/06 , F28F9/16 , F28F19/01 , F28F27/00
摘要： A method of manufacturing a tube sheet by forming a plurality of separate thin tube sheet segments; forming multiple holes in each sheet in a predetermined pattern, each hole for accommodating a tube sheet filter tube; aligning all of the plurality of tube sheet segments so that the hole pattern of each sheet aligns with the hole pattern in all other sheets of the plurality of tube sheet segments; and securing all of the tube sheet segments together to form a unitary tube sheet. A tube sheet construction that includes a plurality of separate thin tube sheet segments, multiple holes being provided in each sheet in a predetermined pattern, each hole for accommodating a tube sheet filter tube, all of the tube sheet segments being aligning so that the hole pattern of each sheet aligns, and fasteners for securing all of the tube sheet segments together. A media layer is provided between adjacent sheet segments.

5. 发明申请

US20160101992A1 MULTI-SEGMENTED TUBE SHEET 有权
标题翻译：多分支管板
公开(公告)号：US20160101992A1
公开(公告)日：2016-04-14
申请号：US14830956
申请日：2015-08-20
申请人： Paul F. Nehlen, III
发明人： Paul F. Nehlen, III
IPC分类号： C02F1/32 , C02F1/68 , F16L9/00
CPC分类号： B01D35/30 , A61M1/0259 , A61M5/44 , B01D15/361 , B01D29/018 , B01D29/56 , B01D35/06 , B01D2201/0446 , B01D2313/025 , C02F1/325 , C02F1/685 , F16L9/00 , F28D2021/005 , F28F9/0221 , F28F9/0229 , F28F9/06 , F28F9/16 , F28F19/01 , F28F27/00
摘要： A method of manufacturing a tube sheet by forming a plurality of separate thin tube sheet segments; forming multiple holes in each sheet in a predetermined pattern, each hole for accommodating a tube sheet filter tube; aligning all of the plurality of tube sheet segments so that the hole pattern of each sheet aligns with the hole pattern in all other sheets of the plurality of tube sheet segments; and securing all of the tube sheet segments together to form a unitary tube sheet. A tube sheet construction that includes a plurality of separate thin tube sheet segments, multiple holes being provided in each sheet in a predetermined pattern, each hole for accommodating a tube sheet filter tube, all of the tube sheet segments being aligning so that the hole pattern of each sheet aligns, and fasteners for securing all of the tube sheet segments together. A media layer is provided between adjacent sheet segments.
摘要翻译：一种通过形成多个分开的细管片段来制造管板的方法; 在每个片材中以预定图案形成多个孔，每个孔用于容纳管板过滤管; 对准所述多个管片段，使得每个片材的孔图案与多个管片段的所有其它片材中的孔图案对准; 并将所有管片段固定在一起以形成整体管板。一种管板结构，其包括多个单独的细管片段，以预定图案设置在每个片材中的多个孔，每个孔用于容纳管板过滤管，所有管片段对齐，使得孔图案和用于将所有管片段固定在一起的紧固件。在相邻片段之间提供介质层。

6. 发明授权

US08795220B2 Blood processing unit with circumferential blood flow 有权
标题翻译：血液处理单元具有周向血流
公开(公告)号：US08795220B2
公开(公告)日：2014-08-05
申请号：US12947171
申请日：2010-11-16
申请人： Stefano Reggiani , Gianfranco Beniamino Fiore , Alberto Giri , Alberto Redaelli , Claudio Silvestri , Gabriele Tommasi
发明人： Stefano Reggiani , Gianfranco Beniamino Fiore , Alberto Giri , Alberto Redaelli , Claudio Silvestri , Gabriele Tommasi
IPC分类号： A61M1/36 , A61M1/16 , B01D63/02
CPC分类号： A61M1/1698 , A61M1/32 , A61M1/3627 , A61M1/3666 , A61M1/3667 , A61M2206/10 , A61M2206/14 , A61M2206/16 , A61M2206/18 , A61M2206/20 , B01D63/02 , B01D2313/08 , B01D2313/19 , B01D2313/32 , B01D2313/38 , F28D7/103 , F28D7/1623 , F28D21/0015 , F28D2021/005 , F28F13/06 , F28F21/06 , F28F21/062 , F28F2260/00 , Y10S128/03 , Y10S261/28
摘要： A blood processing apparatus may include a heat exchanger and a gas exchanger. At least one of the heat exchanger and the gas exchanger may be configured to provide a circumferential blood flow through the heat exchanger and/or gas exchanger.
摘要翻译：血液处理装置可以包括热交换器和气体交换器。热交换器和气体交换器中的至少一个可以构造成提供通过热交换器和/或气体交换器的圆周血流。

7. 发明授权

US08747742B2 Heat exchanger and heat-exchanger-integrated oxygenator 有权
标题翻译：热交换器和热交换器整合式氧合器
公开(公告)号：US08747742B2
公开(公告)日：2014-06-10
申请号：US13578971
申请日：2011-02-15
申请人： Shin-ichi Kawamura , Kazuhisa Ishihara , Naoaki Yasumura
发明人： Shin-ichi Kawamura , Kazuhisa Ishihara , Naoaki Yasumura
IPC分类号： A61M37/00
CPC分类号： A61M1/1698 , A61M2205/366 , A61M2206/10 , A61M2206/11 , B01D63/02 , B01D2313/21 , F28D7/1669 , F28D2021/005 , F28F9/0265 , F28F9/24
摘要： A heat exchanger includes a case, a bottom member and a plurality of heat transfer pipes (a pipe group) loaded in the heat exchanger case, in which blood flows from one end through the bottom member. The bottom member has an annular wall, a bottom surface, and a blood inlet port. The bottom surface is opposed to one end of the heat transfer pipe. The bottom surface includes a groove portion and a raised bottom portion provided on each of opposing end sides of the groove portion. The raised bottom portion is inclined such that a distance between the raised bottom portion on a side where the blood inlet port is provided and one end of the heat transfer pipe is smaller than a distance between the raised bottom portion opposite to the side where the blood inlet port is provided and one end of the heat transfer pipe.
摘要翻译：热交换器包括壳体，底部构件和装载在热交换器壳体中的多个传热管（管道组），其中血液从一端流过底部构件。底部构件具有环形壁，底面以及血液入口。底面与传热管的一端相对。底面包括设置在槽部的相对端侧的槽部和凸起底部。凸起的底部部分倾斜使得设置血液入口侧的凸起的底部与传热管的一端之间的距离小于与血液的一侧相反的凸起的底部之间的距离进口端口和传热管的一端。

8. 发明申请

US20120321512A1 HEAT EXCHANGER AND HEAT-EXCHANGER-INTEGRATED OXYGENATOR 有权
标题翻译：热交换器和热交换器一体化氧化剂
公开(公告)号：US20120321512A1
公开(公告)日：2012-12-20
申请号：US13578971
申请日：2011-02-15
申请人： Shin-ichi Kawamura , Kazuhisa Ishihara , Naoaki Yasumura
发明人： Shin-ichi Kawamura , Kazuhisa Ishihara , Naoaki Yasumura
IPC分类号： A61M1/36 , A61M1/14 , A61M1/18
CPC分类号： A61M1/1698 , A61M2205/366 , A61M2206/10 , A61M2206/11 , B01D63/02 , B01D2313/21 , F28D7/1669 , F28D2021/005 , F28F9/0265 , F28F9/24
摘要： A heat exchanger includes a case, a bottom member and a plurality of heat transfer pipes (a pipe group) loaded in the heat exchanger case, in which blood flows from one end through the bottom member. The bottom member has an annular wall, a bottom surface, and a blood inlet port. The bottom surface is opposed to one end of the heat transfer pipe. The bottom surface includes a groove portion and a raised bottom portion provided on each of opposing end sides of the groove portion. The raised bottom portion is inclined such that a distance between the raised bottom portion on a side where the blood inlet port is provided and one end of the heat transfer pipe is smaller than a distance between the raised bottom portion opposite to the side where the blood inlet port is provided and one end of the heat transfer pipe.
摘要翻译：热交换器包括壳体，底部构件和装载在热交换器壳体中的多个传热管（管道组），其中血液从一端流过底部构件。底部构件具有环形壁，底面以及血液入口。底面与传热管的一端相对。底面包括设置在槽部的相对端侧的槽部和凸起底部。凸起的底部部分倾斜使得设置血液入口侧的凸起的底部与传热管的一端之间的距离小于与血液的一侧相反的凸起的底部之间的距离进口端口和传热管的一端。

9. 发明申请

US20120046594A1 BLOOD PROCESSING UNIT WITH MODIFIED FLOW PATH 有权
标题翻译：血液加工单元改造流程
公开(公告)号：US20120046594A1
公开(公告)日：2012-02-23
申请号：US12860062
申请日：2010-08-20
申请人： Stefano Reggiani , Gianfranco Beniamino Fiore , Alberto Redaelli , Christian Baiotto
发明人： Stefano Reggiani , Gianfranco Beniamino Fiore , Alberto Redaelli , Christian Baiotto
IPC分类号： A61M1/18
CPC分类号： A61M1/1698 , A61M1/32 , A61M1/3627 , A61M1/3666 , A61M1/3667 , A61M2206/10 , A61M2206/14 , A61M2206/16 , A61M2206/18 , A61M2206/20 , B01D63/02 , B01D2313/08 , B01D2313/19 , B01D2313/32 , B01D2313/38 , F28D7/103 , F28D7/1623 , F28D21/0015 , F28D2021/005 , F28F13/06 , F28F21/06 , F28F21/062 , F28F2260/00 , Y10S128/03 , Y10S261/28
摘要： A blood processing apparatus may include a heat exchanger and a gas exchanger. At least one of the heat exchanger and the gas exchanger may be configured to impart a radial component to blow flow through the heat exchanger and/or gas exchanger. The heat exchanger may be configured to cause blood flow to follow a spiral flow path.
摘要翻译：血液处理装置可以包括热交换器和气体交换器。热交换器和气体交换器中的至少一个可以被配置成赋予径向分量以吹动通过热交换器和/或气体交换器。热交换器可以被配置为使血液流动遵循螺旋流动路径。

10. 发明申请

US20060293734A1 Apparatus and method for providing enhanced heat transfer from a body 有权
标题翻译：用于提供来自身体的增强的热传递的装置和方法
公开(公告)号：US20060293734A1
公开(公告)日：2006-12-28
申请号：US11413564
申请日：2006-04-27
申请人： David Scott , Ben Brian , Lloyd Wright , Leo Chin , Edward Hollmen , Daniel Seegars , Mark Logan
发明人： David Scott , Ben Brian , Lloyd Wright , Leo Chin , Edward Hollmen , Daniel Seegars , Mark Logan
IPC分类号： A61F7/00 , A61F7/12
CPC分类号： A61F7/12 , A61F2007/0054 , A61F2007/0093 , A61F2007/0095 , A61F2007/126 , A61M1/369 , A61M2205/3372 , F28D2021/005 , F28F2280/02
摘要： Methods and apparatuses for temperature modification of a patient, or selected regions thereof, including an induced state of hypothermia. The temperature modification is accomplished using an in-dwelling heat exchange catheter within which a fluid heat exchange medium circulates. A heat exchange cassette is attached to the circulatory conduits of the catheter, the heat exchange cassette being sized to engage a cavity within a control unit. The control unit includes a heater/cooler device for providing heated or cooled fluid to a heat exchanger in thermal communication with the fluid heat exchange medium circulating to the heat exchange catheter, a user input device, and a processor connected to receive input from various sensors around the body and the system. A temperature control scheme for ramping the body temperature up or down without overshoot is provided.
摘要翻译：包括诱导低温的状态的患者的温度改变方法和装置，或其选定区域。使用在其中流体热交换介质循环的内部热交换导管来实现温度改变。热交换盒附接到导管的循环导管，热交换盒的尺寸设计成与控制单元内的空腔接合。控制单元包括加热器/冷却器装置，用于将热或冷却的流体提供给与循环到热交换导管的流体热交换介质热连通的热交换器，用户输入装置和连接以从各种传感器接收输入的处理器围绕身体和系统。提供了一种用于使体温上升或下降而没有过冲的温度控制方案。

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