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1. 发明授权

US08147447B2 High precision infusion pump controller 有权
标题翻译：高精度输液泵控制器
公开(公告)号：US08147447B2
公开(公告)日：2012-04-03
申请号：US12678417
申请日：2008-09-17
申请人： Satish Sundar , Swaminathan Balakrishnan , Ivan Melnyk
发明人： Satish Sundar , Swaminathan Balakrishnan , Ivan Melnyk
IPC分类号： A61M37/00
CPC分类号： A61M5/16813 , A61M5/141 , A61M5/1411 , A61M5/1454 , A61M5/1456 , A61M5/14586 , A61M5/1684 , A61M5/16881 , A61M5/1689 , A61M5/172 , A61M2205/3306 , A61M2205/3317 , A61M2205/3389 , A61M2205/3592 , G06F19/00 , Y10S128/12 , Y10S128/13
摘要： A controller for closed loop control of infusion devices is described. A variety of infusion systems are described that use the closed loop control architecture. In some embodiments the closed loop control may be adapted to current commonly used infusion means such as a gravity feed intravenous system. Other embodiments describe infusion pump system that use biasing or drive mechanisms of springs, elastomers, rotary and linear motors.
摘要翻译：描述了用于输液装置闭环控制的控制器。描述了使用闭环控制架构的各种输注系统。在一些实施例中，闭环控制可适用于当前常用的输注装置，例如重力给料静脉内系统。其他实施例描述了使用弹簧，弹性体，旋转和线性马达的偏置或驱动机构的输注泵系统。

2. 发明申请

US20110275904A1 AMBULATORY MEDICAL APPARATUS WITH HAND HELD COMMUNICATION DEVICE 有权
标题翻译：具有手持通信设备的医疗设备
公开(公告)号：US20110275904A1
公开(公告)日：2011-11-10
申请号：US13039259
申请日：2011-03-02
申请人： Ronald J. Lebel , Varaz Shahmirian , Daniel H. Villegas , David Y. Choy , Philip T. Weiss , Paul M. Meadows
发明人： Ronald J. Lebel , Varaz Shahmirian , Daniel H. Villegas , David Y. Choy , Philip T. Weiss , Paul M. Meadows
IPC分类号： A61M5/172 , A61M5/142 , H01R43/00 , A61B5/00
CPC分类号： A61M5/172 , A61B5/0002 , A61B5/14532 , A61B5/6847 , A61B2560/0209 , A61M5/14244 , A61M5/14276 , A61M5/168 , A61M5/16831 , A61M2005/14208 , A61M2205/18 , A61M2205/3507 , A61M2205/3523 , A61M2205/50 , A61M2205/581 , A61M2205/582 , A61M2205/6018 , A61M2205/8206 , A61M2207/00 , A61N1/37211 , A61N1/37247 , A61N1/37252 , A61N1/37258 , A61N1/37264 , A61N1/3727 , A61N1/37276 , A61N1/375 , G06F3/0619 , G06F3/065 , G06F3/0673 , G06F8/60 , G06F8/65 , G06F19/00 , G06F19/3468 , G06Q50/22 , G16H40/40 , Y02D10/42 , Y10S128/13 , Y10S128/903 , Y10T29/49117 , Y10T29/49826
摘要： A communication device (CD) exchanges messages with an implantable infusion pump via telemetry such that commands are supplied thereto and operational information is obtained therefrom. The CD is controlled, at least in part, by a processor IC according to a software program operating therein and provides feedback to a user via a visual display, an audio alarm, and a vibrational alarm, and allows input from the user via a touch sensitive keypad. Certain input functions are restricted by password. The visual display includes an icon and fixed element display region and a bitmap display region. The fixed element display region includes time and date displays, battery and drug level displays that decrement, and a moving delivery state display. Various screens allow operational or log information to be displayed and/or user entry of commands. Program features when disabled are removed from a series of screen options that can be scrolled through.
摘要翻译：通信设备（CD）通过遥测与可植入输液泵交换消息，从而向其提供命令并获得操作信息。 CD至少部分地由处理器IC根据其中操作的软件程序进行控制，并通过视觉显示，音频报警和振动报警向用户提供反馈，并允许用户通过触摸进行输入敏感键盘。某些输入功能受密码限制。视觉显示器包括图标和固定元件显示区域和位图显示区域。固定元件显示区域包括时间和日期显示，递减的电池和药物水平显示以及移动的传送状态显示。各种屏幕允许显示操作或日志信息和/或用户输入命令。禁用时的程序功能从可以滚动的一系列屏幕选项中删除。

3. 发明授权

US07977586B2 Weight sensor and balance controller for a blood purification system 有权
标题翻译：血液净化系统的重量传感器和平衡控制器
公开(公告)号：US07977586B2
公开(公告)日：2011-07-12
申请号：US12296535
申请日：2007-04-12
申请人： Junya Fujii , Shogo Kamito , Toshiyuki Endo , Youichi Sansho
发明人： Junya Fujii , Shogo Kamito , Toshiyuki Endo , Youichi Sansho
IPC分类号： G01G17/04 , G01G21/16 , G01G3/14 , A61M1/14 , A61M1/34
CPC分类号： G01G17/04 , A61M1/1613 , A61M1/1643 , A61M1/3417 , A61M1/3437 , A61M1/3441 , A61M1/3451 , Y10S128/13
摘要： A weight sensor includes an arm having an end fixed to a pillar and a free end; a filtrate holder, a replacement fluid holder, and a dialysate holder provided at three locations of the arm along a longitudinal direction of the arm to hold respective substances; a first strain value sensor, a second strain value sensor, and a third strain value sensor each of which detects a strain value of the arm corresponding to a total weight of the substances held by the holders ranging from a holder proximate to the free end to a corresponding holder; and a weight calculation unit that calculates the total and each of the weights from the obtained detection results.
摘要翻译：重量传感器包括具有固定到支柱和自由端的端部的臂; 滤液保持器，置换液体保持器和透镜液体保持器，其沿臂的纵向方向设置在臂的三个位置处以保持各个物质; 第一应变值传感器，第二应变值传感器和第三应变值传感器，每个传感器检测臂的应变值，其对应于从保持器接近自由端的持有者所持有的物质的总重量，相应的持有人以及权重计算单元，其根据所获得的检测结果计算总和和每个权重。

4. 发明申请

US20110125095A1 MICROPROCESSOR CONTROLLED AMBULATORY MEDICAL APPARATUS WITH HAND HELD COMMUNICATION DEVICE 审中-公开
公开(公告)号：US20110125095A1
公开(公告)日：2011-05-26
申请号：US12913234
申请日：2010-10-27
申请人： RONALD J. LEBEL , Timothy J. Starkweather , Philip T. Weiss
发明人： RONALD J. LEBEL , Timothy J. Starkweather , Philip T. Weiss
IPC分类号： A61M5/168
CPC分类号： A61M5/172 , A61B5/0002 , A61B5/14532 , A61B5/6847 , A61B2560/0209 , A61M5/14244 , A61M5/14276 , A61M5/168 , A61M5/16831 , A61M2005/14208 , A61M2205/18 , A61M2205/3507 , A61M2205/3523 , A61M2205/50 , A61M2205/581 , A61M2205/582 , A61M2205/6018 , A61M2205/8206 , A61M2207/00 , A61N1/37211 , A61N1/37247 , A61N1/37252 , A61N1/37258 , A61N1/37264 , A61N1/3727 , A61N1/37276 , A61N1/375 , G06F3/0619 , G06F3/065 , G06F3/0673 , G06F8/60 , G06F8/65 , G06F19/00 , G06F19/3468 , G06Q50/22 , G16H40/40 , Y02D10/42 , Y10S128/13 , Y10S128/903 , Y10T29/49117 , Y10T29/49826
摘要： An implantable infusion pump possesses operational functionality that is, at least in part, controlled by software operating in two processor ICs which are configured to perform some different and some duplicate functions. The pump exchanges messages with an external device via telemetry. Each processor controls a different part of the drug infusion mechanism such that both processors must agree on the appropriateness of drug delivery for infusion to occur. Delivery accumulators are incremented and decremented with delivery requests and with deliveries made. When accumulated amounts reach or exceed, quantized deliverable amounts, infusion is made to occur. The accumulators are capable of being incremented by two or more independent types of delivery requests. Operational modes of the infusion device are changed automatically in view of various system errors that are trapped, various system alarm conditions that are detected, and when excess periods of time lapse between pump and external device interactions.

5. 发明申请

US20080208484A1 APPARATUS AND METHOD FOR AIR-IN-LINE DETECTION 有权
标题翻译：用于空中在线检测的装置和方法
公开(公告)号：US20080208484A1
公开(公告)日：2008-08-28
申请号：US11563658
申请日：2006-11-27
申请人： Robert D. Butterfield , Allen B. Farquhar
发明人： Robert D. Butterfield , Allen B. Farquhar
IPC分类号： G01N33/00 , G08B21/00
CPC分类号： G01N29/38 , A61M5/14228 , A61M5/365 , G01N29/032 , G01N2291/02433 , Y10S128/13
摘要： The concentration of air or other agents in a fluid delivery line is determined by monitoring agent signals and processing those agent signals along with information regarding the age of each agent signal. The processor determines a primary agent concentration value based on the received agent signal values, with the primary agent concentration value determined by giving greater weight to more recent agent signal values. Where the primary agent concentration value exceeds a primary threshold value, an alarm signal may be activated. The processor also may determine a secondary agent concentration value, which may be determined from the actual agent signal values instead of the weighted agent signal values. Where the secondary agent concentration value exceeds a secondary threshold value, an alarm signal may be activated.
摘要翻译：流体输送管线中的空气或其他试剂的浓度通过监测试剂信号和处理那些试剂信号以及关于每个试剂信号的年龄的信息来确定。处理器基于接收的代理信号值来确定主代理集中值，其中通过对更近的代理信号值给予更大的权重来确定主代理集中度值。当主剂浓度值超过主要阈值时，可以激活报警信号。处理器还可以确定次级剂量浓度值，其可以根据实际代理信号值而不是加权代理信号值来确定。当副试剂浓度值超过次级阈值时，可以激活报警信号。

6. 发明授权

US07347819B2 Ambulatory medical apparatus and method using a robust communication protocol 有权
标题翻译：动态医疗设备和方法使用健壮的通信协议
公开(公告)号：US07347819B2
公开(公告)日：2008-03-25
申请号：US10867786
申请日：2004-06-15
申请人： Ronald J. Lebel , Varaz Shahmirian , Sam W. Bowman, IV , Timothy J. Starkweather , Philip T. Weiss , Robert C. Dennard , John T. Armstrong , John D. Richert
发明人： Ronald J. Lebel , Varaz Shahmirian , Sam W. Bowman, IV , Timothy J. Starkweather , Philip T. Weiss , Robert C. Dennard , John T. Armstrong , John D. Richert
IPC分类号： A61B5/00
CPC分类号： A61M5/172 , A61B5/0002 , A61B5/14532 , A61B5/6847 , A61B2560/0209 , A61M5/14244 , A61M5/14276 , A61M5/168 , A61M5/16831 , A61M2005/14208 , A61M2205/18 , A61M2205/3507 , A61M2205/3523 , A61M2205/50 , A61M2205/581 , A61M2205/582 , A61M2205/6018 , A61M2205/8206 , A61M2207/00 , A61N1/37211 , A61N1/37247 , A61N1/37252 , A61N1/37258 , A61N1/37264 , A61N1/3727 , A61N1/37276 , A61N1/375 , G06F3/0619 , G06F3/065 , G06F3/0673 , G06F8/60 , G06F8/65 , G06F19/00 , G06F19/3468 , G06Q50/22 , G16H40/40 , Y02D10/42 , Y10S128/13 , Y10S128/903 , Y10T29/49117 , Y10T29/49826
摘要： An implanted medical device (e.g. infusion pump) and external device communicate with one another via telemetry wherein messages are transmitted under a robust communication protocol. The communication protocol gives enhanced assurance concerning the integrity of messages that impact medical operations of the implantable device. Messages are transmitted using a multipart format that includes a preamble, a frame sync, a telemetry ID, data, and a validation code. The data portion of the message includes an op-code that dictates various other elements that form part of the message. The data portion may also include additional elements such as sequence numbers, bolus numbers, and duplicate data elements. A telemetry ID for the transmitting device may be implicitly embedded in the message as part of the validation code that is sent with the message and that must be pre-known by the receiver to confirm the integrity of the received message.
摘要翻译：植入式医疗设备（例如输液泵）和外部设备通过遥测来彼此通信，其中消息在鲁棒的通信协议下传输。通信协议增强了对影响可植入设备的医疗操作的消息的完整性的保证。使用包括前同步码，帧同步，遥测ID，数据和验证码的多部分格式发送消息。消息的数据部分包括指示形成消息的一部分的各种其他元素的操作码。数据部分还可以包括附加元件，例如序列号，推注号和重复数据元素。用于发送设备的遥测ID可以隐式地嵌入消息中，作为与消息一起发送的确认代码的一部分，并且必须由接收者预先知道用于确认接收到的消息的完整性。

7. 发明申请

US20080045834A1 SYSTEM AND METHOD FOR DELIVERING FLUIDS TO A BALLOON CATHETER 审中-公开
标题翻译：将流体输送到气泡导管的系统和方法
公开(公告)号：US20080045834A1
公开(公告)日：2008-02-21
申请号：US11842325
申请日：2007-08-21
申请人： Arthur Uber , Alan Hirschman , Thomas Welch , Rosemary Almon-Martin
发明人： Arthur Uber , Alan Hirschman , Thomas Welch , Rosemary Almon-Martin
IPC分类号： A61B6/00
CPC分类号： A61B8/06 , A61B8/481 , A61M5/007 , A61M5/1723 , A61M2205/581 , A61M2205/80 , G06F19/321 , G06F19/3468 , Y10S128/12 , Y10S128/13
摘要： A fluid delivery system includes a first pressurizing device, a second pressurizing device, a reusable fluid path for delivering fluid to multiple patients and a per-patient disposable fluid path adapted to be connected to the reusable fluid path and operable to deliver fluid media to a balloon catheter in a patient. The reusable fluid path includes a first portion in fluid communication with a first source of fluid medium and a second portion in fluid communication with a second source of fluid medium. The first pressurizing device is associated with the first portion of the reusable fluid path and the second pressurizing device is associated with the second portion of the reusable fluid path. A control unit in communication with the first and second pressurizing devices is adapted to actuate the first and second pressurizing devices to deliver one or both of the fluid media to a balloon on the balloon catheter.
摘要翻译：流体递送系统包括第一加压装置，第二加压装置，用于将流体输送到多个患者的可重复使用的流体路径，以及适于连接到可重复使用的流体路径并且可操作以将流体介质输送到气囊导管在病人身上。可重复使用的流体路径包括与第一流体介质源流体连通的第一部分和与第二流体介质源流体连通的第二部分。第一加压装置与可再利用流体路径的第一部分相关联，第二加压装置与可重复使用流体路径的第二部分相关联。与第一和第二加压装置连通的控制单元适于致动第一和第二加压装置，以将一种或两种流体介质输送到球囊导管上的气球。

8. 发明授权

US07201733B2 Drug delivery system for implantable cardiac device 失效
标题翻译：用于植入式心脏装置的药物递送系统
公开(公告)号：US07201733B2
公开(公告)日：2007-04-10
申请号：US09999260
申请日：2001-11-30
申请人： Avram Scheiner , Mark Herner , Ronald W. Heil, Jr. , Steven D. Girouard
发明人： Avram Scheiner , Mark Herner , Ronald W. Heil, Jr. , Steven D. Girouard
IPC分类号： A61M31/00
CPC分类号： A61N1/30 , A61N1/3621 , Y10S128/12 , Y10S128/13
摘要： A drug delivery system incorporated into a cardiac device for delivering a dose of a drug to a patient upon detection of a particular medical condition. The cardiac device may be, for example, an implantable cardioverter/defibrillator, cardiac pacemaker, or combination device that communicates via a radio frequency link with a drug delivery device. The drug delivery device is preferably an electrically modulated transdermal drug delivery device for delivering the drug transdermally in accordance with a signal received from the cardiac device.
摘要翻译：一种药物递送系统，其结合到心脏装置中，用于在检测到特定医疗状况时将药物的剂量递送给患者。心脏装置可以是例如通过射频链路与药物递送装置进行通信的可植入式心律转复器/除颤器，心脏起搏器或组合装置。药物递送装置优选是经电调制的透皮药物递送装置，用于根据从心脏装置接收的信号透皮地递送药物。

9. 发明授权

US07171274B2 Method and apparatus for communicating between an ambulatory medical device and a control device via telemetry using randomized data 有权
标题翻译：通过使用随机数据通过遥测来在流动医疗装置和控制装置之间进行通信的方法和装置
公开(公告)号：US07171274B2
公开(公告)日：2007-01-30
申请号：US10437366
申请日：2003-05-12
申请人： Timothy J. Starkweather , Ronald J. Lebel , Daniel H. Villegas , Philip T. Weiss , John T. Armstrong , John D. Richert
发明人： Timothy J. Starkweather , Ronald J. Lebel , Daniel H. Villegas , Philip T. Weiss , John T. Armstrong , John D. Richert
IPC分类号： A61N1/08
CPC分类号： A61M5/172 , A61B5/0002 , A61B5/14532 , A61B5/6847 , A61B2560/0209 , A61M5/14244 , A61M5/14276 , A61M5/168 , A61M5/16831 , A61M2005/14208 , A61M2205/18 , A61M2205/3507 , A61M2205/3523 , A61M2205/50 , A61M2205/581 , A61M2205/582 , A61M2205/6018 , A61M2205/8206 , A61M2207/00 , A61N1/37211 , A61N1/37247 , A61N1/37252 , A61N1/37258 , A61N1/37264 , A61N1/3727 , A61N1/37276 , A61N1/375 , G06F3/0619 , G06F3/065 , G06F3/0673 , G06F8/60 , G06F8/65 , G06F19/00 , G06F19/3468 , G06Q50/22 , G16H40/40 , Y02D10/42 , Y10S128/13 , Y10S128/903 , Y10T29/49117 , Y10T29/49826
摘要： An implanted medical device (e.g. infusion pump) and handheld communication device communicate with one another via telemetry wherein transmitted messages have enhanced numbers of and/or regularity of bit transitions to minimize the risk of synchronization loss between transmitted bits of data and received bits of data. Bit transitions for portions of messages may be enhanced by applying a pseudo-randomization scheme to those portions of messages that are transmitted in a way that allows the receiver to extract the original data from the received randomized data. Preferred randomization techniques modify (i.e. randomize) the data using a CRC value that is being accumulated while simultaneously causing the modified data to modify subsequent accumulation of the CRC itself. Upon reception, the reversal of data randomization occurs so that the intended message is appropriately received.
摘要翻译：植入式医疗设备（例如输液泵）和手持通信设备通过遥测来相互通信，其中传输的消息具有增强的位转换数量和/或规则性，以最小化发送的数据位和数据位之间的同步丢失的风险。可以通过将伪随机化方案应用于以允许接收机从接收到的随机数据中提取原始数据的方式发送的消息的那些部分来增强消息部分的位转换。优选的随机化技术使用正在累积的CRC值来修改（即随机化）数据，同时使修改的数据修改CRC本身的后续累积。在接收时，发生数据随机化的反转，从而恰当地接收预期的消息。

10. 发明申请

US20050278072A1 Flow monitoring system for a flow control apparatus 有权
标题翻译：用于流量控制装置的流量监测系统
公开(公告)号：US20050278072A1
公开(公告)日：2005-12-15
申请号：US10853926
申请日：2004-05-25
申请人： Robert Gaines , Joseph Hudson
发明人： Robert Gaines , Joseph Hudson
IPC分类号： G05D7/00 , G05D7/06
CPC分类号： A61M5/14232 , A61M5/16831 , A61M2005/16868 , A61M2005/16872 , A61M2205/3351 , A61M2205/3375 , G05D7/0688 , Y10S128/13
摘要： A flow control apparatus having a flow monitoring system capable of detecting and identifying flow present within the administration feeding set loaded to the flow control apparatus is disclosed. The flow control apparatus comprises a single sensor capable of detecting the presence or absence of fluid in the administration feeding set. A software subsystem may be operatively associated with the single sensor that is capable of identifying between upstream and downstream flow conditions present within the administration feeding set loaded to the flow control apparatus.
摘要翻译：公开了一种具有流量监测系统的流量控制装置，该系统能够检测和识别加载到流量控制装置内的管理供给装置内存在的流量。流量控制装置包括能够检测给药给药装置中存在或不存在流体的单个传感器。软件子系统可以与单个传感器可操作地相关联，该传感器能够识别存在于加载到流量控制装置的管理进料组中的上游和下游流动条件之间。

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