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1. 发明申请

US20210020943A1 Redox Flow Battery Electrolytes 有权
公开(公告)号：US20210020943A1
公开(公告)日：2021-01-21
申请号：US16968732
申请日：2019-02-13
申请人： CMBLU PROJEKT AG
发明人： Jan HARTWIG , Peter GEIGLE , Evgeny LARIONOV
IPC分类号： H01M4/60 , H01M8/18 , H01M8/04186 , H01M4/36 , C07G1/00 , C07C309/14 , C07C39/24 , C07C309/42 , C07C215/50 , C07C309/44
摘要： The present invention relates to novel combinations of redox active compounds for use as redox flow battery electrolytes. The invention further provides kits comprising these combinations, redox flow batteries, and method using the combinations, kits and redox flow batteries of the invention.

2. 发明授权

US10562837B2 Preparation of phenyl compounds 有权
公开(公告)号：US10562837B2
公开(公告)日：2020-02-18
申请号：US16064287
申请日：2016-12-22
申请人： Nederlandse Organisatie voor toegepast-natuurwetenschappelijk onderzoek TNO
发明人： Marc Crockatt , Jan Harm Urbanus , Paul Mathijs Könst
IPC分类号： C07D307/00 , C07C67/31 , C07C37/50 , C07C309/42 , C07C309/58 , C07C51/09 , C07C309/32 , C07C303/22 , C07C309/44 , C07C309/75 , C07C309/77
摘要： The invention relates to a method for preparing a compound comprising two phenyl groups by reacting a bisfuranic compound with a dienophile; and to such compounds.

3. 发明授权

US09553326B2 Aromatic sulfonic acid derivative, sulfonic acid group-containing polymer, block copolymer, polymer electrolyte material, polymer electrolyte form article, and polymer electrolyte fuel cell 有权
标题翻译：芳族磺酸衍生物，含磺酸基的聚合物，嵌段共聚物，聚合物电解质材料，聚合物电解质成型体和聚合物电解质燃料电池
公开(公告)号：US09553326B2
公开(公告)日：2017-01-24
申请号：US14843695
申请日：2015-09-02
申请人： TORAY INDUSTRIES, INC.
发明人： Daisuke Izuhara , Hiroaki Umeda , Emi Amano , Tomoyuki Kunita
IPC分类号： C08G75/24 , C08G65/40 , C07C317/22 , H01B1/12 , C07C309/60 , H01M8/10 , C07C309/44 , H01B1/06 , H01M4/86 , H01M8/02
CPC分类号： H01M8/1032 , C07C309/44 , C07C309/60 , C07C317/22 , C08G65/40 , C08G65/4012 , C08G65/4056 , C08G2650/40 , H01B1/122 , H01M8/1025 , H01M8/1027 , H01M8/1039 , H01M2008/1095 , H01M2300/0082 , Y02E60/521
摘要： Provided are an aromatic sulfonic acid derivative and a sulfonic acid group-containing polymer, each of which has excellent proton conductivity even under low humidification conditions, while having excellent mechanical strength and chemical stability, and enables a solid polymer fuel cell to achieve high output and excellent physical durability when used therein. This aromatic sulfonic acid derivative has a specific structure and is characterized in that a sulfonic acid group is introduced into more than 50% of all the phenyl groups. This sulfonic acid group-containing polymer is characterized by being obtained by polymerization using the aromatic sulfonic acid derivative, and is also characterized by having a specific structure.
摘要翻译：提供了即使在低加湿条件下也具有优异的质子传导性的芳香族磺酸衍生物和含磺酸基的聚合物，同时具有优异的机械强度和化学稳定性，并且能够使固体高分子型燃料电池实现高输出，使用时具有良好的物理耐久性。该芳香族磺酸衍生物具有特定的结构，其特征在于，在全部苯基的50％以上引入磺酸基。该含磺酸基的聚合物的特征在于通过使用芳香族磺酸衍生物的聚合得到，特征在于具有特定的结构。

4. 发明申请

US20160333033A1 O-Phenyl Chalcone Compounds And Preparation Method And Use Thereof 有权
标题翻译： O-苯基查耳酮化合物及其制备方法和用途
公开(公告)号：US20160333033A1
公开(公告)日：2016-11-17
申请号：US15218738
申请日：2016-07-25
申请人： Sun Yat-Sen University
发明人： Xianzhang Bu , Cuige Zhu , Xin Yue , Yinglin Zuo , Yu Chen , Gesi Wen
IPC分类号： C07F9/12 , C07C225/22 , C07C221/00 , C07C49/84 , C07C45/45 , C07C303/22 , C07C255/56 , C07C253/30 , C07D207/08 , C07C65/38 , C07C51/347 , C07C309/44 , C07F5/02 , C07C49/835
CPC分类号： C07F9/12 , C07C45/45 , C07C45/63 , C07C49/248 , C07C49/255 , C07C49/835 , C07C49/84 , C07C51/347 , C07C51/373 , C07C65/38 , C07C221/00 , C07C225/22 , C07C253/30 , C07C255/56 , C07C303/22 , C07C309/44 , C07D207/08 , C07D295/112 , C07D295/12 , C07F5/025 , C07C49/813
摘要： Disclosed are an o-phenyl chalcone compounds and preparation methods and uses thereof. The o-phenyl chalcone compounds are capable of inhibiting the aggregation of microtubules in tumor cells and influencing the mitosis of the cells, and have a high antitumor activity. The compounds also have inhibitory activity against proliferation on various tumor cells, such as a human ovary cancer cell A2780, a human colon cancer cell HCT8, a human breast cancer cell MCF7, a human lung cancer cell A549, a human colon cancer cell SW480, a human nasopharyngeal carcinoma cell CNE2, a human liver cancer cell HepG2 and the like at nanomole concentrations.
摘要翻译：公开了邻苯基查耳酮化合物及其制备方法和用途。邻苯基查耳酮化合物能够抑制肿瘤细胞中微管的聚集并影响细胞的有丝分裂，并且具有高的抗肿瘤活性。该化合物还具有抑制各种肿瘤细胞增殖的作用，例如人卵巢癌细胞A2780，人结肠癌细胞HCT8，人乳腺癌细胞MCF7，人肺癌细胞A549，人结肠癌细胞SW480，人鼻咽癌细胞CNE2，人肝癌细胞HepG2等纳米摩尔浓度。

5. 发明申请

US20150380759A1 AROMATIC SULFONIC ACID DERIVATIVE, SULFONIC ACID GROUP-CONTAINING POLYMER, BLOCK COPOLYMER, POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE FORM ARTICLE, AND POLYMER ELECTROLYTE FUEL CELL 有权
标题翻译：芳香磺酸衍生物，含硫酸基团聚合物，嵌段共聚物，聚合物电解质材料，聚合物电解质形式和聚合物电解质燃料电池
公开(公告)号：US20150380759A1
公开(公告)日：2015-12-31
申请号：US14843695
申请日：2015-09-02
申请人： TORAY INDUSTRIES, INC.
发明人： Daisuke IZUHARA , Hiroaki UMEDA , Emi AMANO , Tomoyuki KUNITA
IPC分类号： H01M8/10 , C07C317/22 , C07C309/44
CPC分类号： H01M8/1032 , C07C309/44 , C07C309/60 , C07C317/22 , C08G65/40 , C08G65/4012 , C08G65/4056 , C08G2650/40 , H01B1/122 , H01M8/1025 , H01M8/1027 , H01M8/1039 , H01M2008/1095 , H01M2300/0082 , Y02E60/521
摘要： Provided are an aromatic sulfonic acid derivative and a sulfonic acid group-containing polymer, each of which has excellent proton conductivity even under low humidification conditions, while having excellent mechanical strength and chemical stability, and enables a solid polymer fuel cell to achieve high output and excellent physical durability when used therein. This aromatic sulfonic acid derivative has a specific structure and is characterized in that a sulfonic acid group is introduced into more than 50% of all the phenyl groups. This sulfonic acid group-containing polymer is characterized by being obtained by polymerization using the aromatic sulfonic acid derivative, and is also characterized by having a specific structure.
摘要翻译：提供了即使在低加湿条件下也具有优异的质子传导性的芳香族磺酸衍生物和含磺酸基的聚合物，同时具有优异的机械强度和化学稳定性，并且能够使固体高分子型燃料电池实现高输出，使用时具有良好的物理耐久性。该芳香族磺酸衍生物具有特定的结构，其特征在于，在全部苯基的50％以上引入磺酸基。该含磺酸基的聚合物的特征在于通过使用芳香族磺酸衍生物的聚合得到，特征在于具有特定的结构。

6. 发明授权

US09120725B2 Aromatic perfluoroalkane monomer 有权
标题翻译：芳族全氟烷烃单体
公开(公告)号：US09120725B2
公开(公告)日：2015-09-01
申请号：US13812894
申请日：2011-07-06
申请人： Milan Fedurco
发明人： Milan Fedurco
IPC分类号： C07C309/44 , C07C49/825 , C07C49/813 , C07C49/83 , H01M8/10 , C08G65/40 , C08L71/00 , B01D71/66 , C07C49/80 , C08G75/02
CPC分类号： C07C309/44 , B01D71/66 , C07C49/80 , C07C49/813 , C07C49/825 , C07C49/83 , C08G65/4025 , C08G75/02 , C08G2650/40 , C08L71/00 , H01M8/1025 , H01M8/1039 , H01M8/1088 , Y02E60/521 , Y02P70/56
摘要： An aromatic perfluoroalkane monomer is provided that can be used for the manufacture of a polymer membrane for a PEM-type fuel cell. The perfluoroalkane monomer has a structure corresponding to a formula (I): Z1—Ar3—C(O)—Ar1—(CF2)n—Ar2—C(O)—Ar4—Z2 (I) in which: n is in a range from 1 to 20; Ar1, Ar2, Ar3, Ar4 which are identical or different, represent a substituted or unsubstituted phenylene group; and Z1 and Z2, which are identical or different, represent an electrophilic or nucleophilic polymerizable functional group.
摘要翻译：提供了可用于制造用于PEM型燃料电池的聚合物膜的芳族全氟烷烃单体。全氟烷基单体具有对应于式（I）的结构：Z1-Ar3-C（O）-Ar1-（CF2）n-Ar2-C（O）-Ar4-Z2（Ⅰ），其中n为范围从1到20; 相同或不同的Ar 1，Ar 2，Ar 3，Ar 4表示取代或未取代的亚苯基; 和相同或不同的Z 1和Z 2表示亲电或亲核可聚合官能团。

7. 发明申请

US20150004699A1 SMALL MOLECULE XANTHINE OXIDASE INHIBITORS AND METHODS OF USE 有权
标题翻译：小分子XANTHINE氧化酶抑制剂及其使用方法
公开(公告)号：US20150004699A1
公开(公告)日：2015-01-01
申请号：US14483080
申请日：2014-09-10
申请人： Baylor College of Medicine
发明人： Changyi Chen , Jian-Ming Lu , Qizhi Yao
IPC分类号： C07C47/54 , C07C313/04 , C07C309/44 , C07C205/44 , C07C255/56
CPC分类号： A61K31/11 , A61K9/0053 , A61K31/185 , A61K31/277 , A61K31/519 , A61K45/06 , C07C47/54 , C07C47/544 , C07C47/565 , C07C205/44 , C07C255/56 , C07C255/57 , C07C309/44 , C07C313/04 , C07C317/22
摘要： Small molecule xanthine oxidase inhibitors are provided, as well as methods for their use in treating gout or hyperuricemia.
摘要翻译：提供了小分子黄嘌呤氧化酶抑制剂，以及它们用于治疗痛风或高尿酸血症的方法。

8. 发明申请

US20140336258A1 ANTI-VIRULENCE COMPOSITIONS AND METHODS 审中-公开
标题翻译：抗生物组合物和方法
公开(公告)号：US20140336258A1
公开(公告)日：2014-11-13
申请号：US14445713
申请日：2014-07-29
申请人： Case Western Reserve University
发明人： Menachem Shoham
IPC分类号： C07C49/83 , A61K31/12 , A61K31/192 , C07C309/44 , A61K31/185 , C07C65/24 , C07C49/84 , A61K45/06
CPC分类号： C07C49/83 , A61K31/12 , A61K31/166 , A61K31/185 , A61K31/192 , A61K31/36 , A61K31/404 , A61K45/06 , C07C49/84 , C07C65/24 , C07C309/44 , C07C2601/16 , C12N1/36
摘要： A method of reducing the virulence of a bacterium that expresses accessory gene regulator A (AgrA) includes administering to the bacterium an amount of AgrA antagonist effective to inhibit the synthesis of one or more virulence factors by the bacterium.
摘要翻译：降低表达附属基因调节剂A（AgrA）的细菌的毒力的方法包括向细菌施用一定量的有效抑制细菌合成一种或多种毒力因子的AgrA拮抗剂。

9. 发明授权

US08853441B2 Sulfonium compound, photoacid generator, and resist composition 有权
标题翻译：锍化合物，光酸产生剂和抗蚀剂组合物
公开(公告)号：US08853441B2
公开(公告)日：2014-10-07
申请号：US13557893
申请日：2012-07-25
申请人： Jung Hoon Oh , Dae Kyung Yoon , Seung Duk Cho , So Jeong Park
发明人： Jung Hoon Oh , Dae Kyung Yoon , Seung Duk Cho , So Jeong Park
IPC分类号： C07C69/013 , C07C69/017 , C07C309/02 , C07C309/39 , C07C309/44 , C07C381/12 , G03F7/00 , C07C309/12 , G03F7/004 , C07D333/46 , C07C309/06 , C07D307/64 , G03C1/00 , G03F7/039
CPC分类号： C07C309/06 , C07C309/02 , C07C309/12 , C07C381/12 , C07C2602/42 , C07C2603/74 , C07D307/64 , C07D333/46 , G03F7/00 , G03F7/004 , G03F7/0045 , G03F7/0046 , G03F7/0395 , G03F7/0397
摘要： A sulfonium compound represented by the following formula (1), a photoacid generator containing the sulfonium compound, and a resist composition containing the photoacid generator are provided: wherein X represents an electron donor group; R1 and R2 each independently represent an alkyl group or the like; R4 to R6 each independently represent an alkyl group, or the like; R3 represents a cyclic alkenediyl group or the like; and −A represents an anion. The sulfonium compound has a photon yield that is controllable by introducing different absorbers to the cation region in one molecule, can address the inconvenience of using a mixture of different photoacid generators when the sulfonium compound is applied as a photoacid generator, has excellent miscibility in a resist, and has enhanced resolution and line edge roughness.
摘要翻译：提供由下式（1）表示的锍化合物，含有锍化合物的光酸产生剂和含有光酸产生剂的抗蚀剂组合物，其中X表示电子给体基团; R1和R2各自独立地表示烷基等; R4至R6各自独立地表示烷基等; R3表示环状亚烯基等; -A表示阴离子。锍化合物具有通过在一个分子中向阳离子区域引入不同吸收剂可控制的光子产率，可以解决当将锍化合物用作光致酸发生剂时使用不同光酸产生剂的混合物的不便之处，在抗蚀，并具有增强的分辨率和线边缘粗糙度。

10. 发明授权

US08119833B2 Dendrimer solid acid and polymer electrolyte membrane including the same 有权
标题翻译：树枝状聚合物固体酸和聚合物电解质膜包括相同的
公开(公告)号：US08119833B2
公开(公告)日：2012-02-21
申请号：US13176699
申请日：2011-07-05
申请人： Myung-sup Jung , Jin-gyu Lee , Sang-kook Mah , Jae-jun Lee
发明人： Myung-sup Jung , Jin-gyu Lee , Sang-kook Mah , Jae-jun Lee
IPC分类号： C07C309/32 , C07C309/42 , C07C309/33 , C07C309/44 , H01M8/22
CPC分类号： C08J5/2256 , C08J5/2275 , C08J2300/00 , C08J2300/202 , C08J2379/08
摘要： Provided are a dendrimer solid acid and a polymer electrolyte membrane using the same. The polymer electrolyte membrane includes a macromolecule of a dendrimer solid acid having ionically conductive terminal groups at the surface thereof and a minimum amount of ionically conductive terminal groups required for ionic conduction, thus suppressing swelling and allowing a uniform distribution of the dendrimer solid acid, thereby improving ionic conductivity. Since the number of ionically conductive terminal groups in the polymer electrolyte membrane is minimized and the polymer matrix in which swelling is suppressed is used, methanol crossover and difficulties of outflow due to a large volume may be reduced, and a macromolecule of the dendrimer solid acid having the ionically conductive terminal groups on the surface thereof is uniformly distributed. Accordingly, ionic conductivity is high and thus, the polymer electrolyte membrane shows good ionic conductivity even in non-humidified conditions.
摘要翻译：提供了树枝状聚合物固体酸和使用其的聚合物电解质膜。聚合物电解质膜包括其表面具有离子导电性端基的树枝状聚合物固体酸的高分子和离子传导所需的离子导电性端基的最小量，因此抑制了树枝状聚合物固体酸的均匀分布，从而提高离子电导率。由于聚合物电解质膜中的离子导电性端基的数量被最小化，并且使用抑制了溶胀的聚合物基体，所以甲基交联和体积大的流出困难可能降低，并且树枝状聚合物固体酸的高分子其表面上的离子导电性端基均匀分布。因此，离子电导率高，因此即使在非加湿条件下，高分子电解质膜也具有良好的离子传导性。

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