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1. 发明授权

US11542221B2 α, α-disubstituted carboxylic acid esters for use as aroma chemicals 有权
公开(公告)号：US11542221B2
公开(公告)日：2023-01-03
申请号：US17261420
申请日：2019-07-19
申请人： BASF SE
发明人： Manuel Danz , Ralf Pelzer , Miriam Bru Roig , Florian Garlichs
IPC分类号： C07C69/24 , A61Q13/00
摘要： The present invention relates to the use of an α,α-disubstituted carboxylic acid ester of the general formula (I) wherein the variables are as defined in the claims and the description, or of mixtures of two or more of these α,α-disubstituted carboxylic acid esters or of a stereoisomer thereof or of a mixture of two or more stereoisomers thereof as aroma chemicals; to the use thereof for modifying the scent character of a fragranced composition; to an aroma chemical composition containing an α,α-disubstituted carboxylic acid ester of the general formula (I) or a mixture of two or more of said α,α-disubstituted carboxylic acid esters or of a stereoisomer thereof or of a mixture of two or more stereoisomers thereof; and to a method of preparing a fragranced composition or for modifying the scent character of a fragranced composition. The invention further relates to specific mixtures of α,α-disubstituted carboxylic acid esters of the general formula (I).

2. 发明授权

US11186536B2 Cetylated fatty acids, system for the preparation thereof and use thereof 有权
公开(公告)号：US11186536B2
公开(公告)日：2021-11-30
申请号：US16789289
申请日：2020-02-12
申请人： Pharmanutra S.P.A.
发明人： Andrea Lacorte , Germano Tarantino , Paolo Bondioli
IPC分类号： C07C69/24 , A61K31/23 , C07C67/08 , C11C3/00 , A61P37/02 , A61P9/00 , A61P19/02
摘要： The present invention relates to a process for preparing a mixture of cetylated fatty acids and a system for carrying out said process. Furthermore, the present invention relates to a composition comprising, or alternatively, consisting of said mixture of cetylated fatty acids. Finally, the present invention relates to said composition for use in the treatment and/or prevention of: (i) rheumatoid arthritis of inflammatory and non-inflammatory origin, in particular osteoarthritis; (ii) other inflammatory joint conditions; (iii) psoriasis, lupus, periodontal diseases or cardiovascular or heart diseases; (iv) all post-traumatic osteoarticular pathologies including sports injuries; (v) all degenerative joint pathologies (arthrosis, gonarthrosis, coxarthrosis, etc.), and (vi) inflammatory-traumatic tendon and muscular conditions. Furthermore, it is envisaged that the composition of the present invention be used in the treatment and/or prevention of the above-mentioned pathologies and disorders (i)-(vi) in association with a rehabilitative therapy. The composition comprising said mixture is formulated in a pharmaceutical form for oral use (novel food, supplement or medical device), i.e. in the form of a pill, pastille, capsule, tablet, granules, dispersible powder, syrup, solution or sprayable solution; for topical use, i.e. in the form of a cream, unguent, ointment, gel or spray to be used as such for application on the skin, or else for transdermal use in the form of a patch.

3. 发明授权

US11185851B2 Polymer-supported metal 有权
公开(公告)号：US11185851B2
公开(公告)日：2021-11-30
申请号：US16074473
申请日：2017-02-16
申请人： TAKASAGO INTERNATIONAL CORPORATION
发明人： Yoshimasa Matsushima , Takashi Ohshima
IPC分类号： B01J31/16 , C07J9/00 , C07D473/16 , C07C68/06 , C07C69/96 , C07C43/23 , C07C69/145 , C07C31/125 , C07C33/32 , C07C201/12 , B01J31/06 , C07C33/02 , C07C205/43 , C07C213/06 , C07C219/14 , C07C67/03 , C07C39/20 , C07C69/24 , C07C33/22 , C07C69/78 , C07F7/18 , C07D317/38 , C07C69/14 , C07C37/055 , C07C41/16 , C07C69/157 , B01J37/04 , C07C29/128 , C07C67/02 , C07C67/08 , C07D317/36 , C07B61/00
摘要： A macromolecules containing a metal and a use thereof as a catalyst are disclosed. The macromolecules containing a metal may be obtained by causing a ligand to react with a zinc compound or a cobalt compound. The ligand has an imidazole group that is bonded to a macromolecule via a linker. The metal-containing macromolecules are highly active as a catalyst, stable, and easy to recover and reuse.

4. 发明授权

US11008594B2 Process for the preparation of triple-bond-containing optically active carboxylic acids, carboxylate salts and carboxylic acid derivatives 有权
公开(公告)号：US11008594B2
公开(公告)日：2021-05-18
申请号：US16087402
申请日：2017-03-21
申请人： CHINOIN GYÓGYSZER ÉS VEGYÉSZETI TERMÉKEK GYÁRA ZRT.
发明人： Irén Hortobágyi , István Lászlófi , Zsuzsanna Kardos , József Molnár , László Takács , Tamás Bán
IPC分类号： C12P7/62 , C07F9/40 , C12P7/40 , C12P41/00 , C07C57/18 , C07C69/24
摘要： The invention provides a new enzimatic process for the preparation of chiral carboxylic acids, their salts and acid derivatives of the general formula (I) by enzymatic hydrolysis of racemic carboxylic acid ester of the general formula (II) and optionally subsequent esterification or acylation.

5. 发明授权

US10696686B2 Herbicidally active (alkynyl-phenyl)-substituted cyclic dione compounds and derivatives thereof 有权
公开(公告)号：US10696686B2
公开(公告)日：2020-06-30
申请号：US14894698
申请日：2014-05-29
申请人： Syngenta Limited
发明人： Janice Black , James Nicholas Scutt , Louisa Whalley , Nigel James Willets
IPC分类号： C07D493/08 , A01N43/16 , C07D309/32 , C07D311/96 , C07C49/753 , A01N43/18 , C07C323/22 , A01N43/40 , C07D307/42 , A01N35/06 , A01N37/02 , A01N37/10 , A01N47/06 , C07C49/577 , C07C69/24 , C07C69/78 , C07C69/96 , C07C381/14 , A01N43/90 , C07C49/517
摘要： The present invention relates to a compound of formula (I): wherein: X is methyl or chlorine; R1 is fluorine or bromine; R2 is ethynyl, C1-C3alkoxy, C1-C3haloalkoxy, or C1-C3alkoxy-C1-C3alkoxy-; and Q is a pyran-3,5-dione-4-yl, a thiopyran-3,5-dione-4-yl, a piperidine-3,5-dione-4-yl, a cyclopentane-1,3-dione-2-yl, a cyclohexane-1,3, 5-trione-2-yl, a cyclohexane-1,3-dione-2-yl, or a cycloheptane-1,3-dione-2-yl, or a derivative thereof (e.g. a fused such as fused bicyclic derivative, and/or a spirocyclic derivative), or an enol ketone tautomer derivative thereof, wherein Q is further defined herein; and wherein the compound of formula (I) is optionally present as an agrochemically acceptable salt thereof. Preferably, X is methyl; and/or R1 is fluorine; and/or R2 is —O—R2A, wherein R2A is methyl, ethyl, trifluoromethyl, difluoromethyl, trifluoroethyl, or —CH2CH2OCH3. These compounds are suitable for use as herbicides. The invention therefore also relates to a method of controlling weeds, especially grassy monocotyledonous weeds, in crops of useful plants, comprising applying a compound of formula (I), or a herbicidal composition comprising such a compound, to the weeds and/or to the plants and/or to the locus thereof.

6. 发明授权

US10315189B2 Ethoxylation catalyst and manufacturing method therefor 有权
公开(公告)号：US10315189B2
公开(公告)日：2019-06-11
申请号：US15756962
申请日：2016-09-05
申请人： LION CORPORATION
发明人： Fumiya Niikura
IPC分类号： B01J23/02 , B01J27/053 , B01J37/08 , B01J35/10 , C07C67/03 , C07C69/24 , C07B61/00
摘要： Disclosed is an ethoxylation catalyst having a BET specific surface area of 40 to 150 m2/g and including calcium sulfate particles including at least one kind of compound selected from the group consisting of calcium sulfate 0.5 hydrate and type III anhydrous calcium sulfate.

7. 发明授权

US09976099B2 Low viscosity low volatility lubricating oil base stocks and methods of use thereof 有权
公开(公告)号：US09976099B2
公开(公告)日：2018-05-22
申请号：US15384471
申请日：2016-12-20
申请人： ExxonMobil Research and Engineering Company
发明人： Man Kit Ng , Halou Oumar-Mahamat , Hong Cheng , David A. Blain
IPC分类号： C10M105/34 , C07C69/24 , C07C69/612 , C07C69/614 , C07C69/734 , C07C69/78 , C10M111/02 , C10M129/70 , C10M129/95
CPC分类号： C10M105/34 , C07C69/24 , C07C69/612 , C07C69/614 , C07C69/734 , C07C69/78 , C10M111/02 , C10M129/70 , C10M129/95 , C10M2203/024 , C10M2207/281 , C10M2207/2815 , C10M2207/284 , C10M2207/2845 , C10N2220/022 , C10N2230/02 , C10N2230/04 , C10N2230/06 , C10N2230/08 , C10N2230/10 , C10N2230/74 , C10N2240/04 , C10N2240/10
摘要： A composition including one or more aromatic alkanoate monoester compounds represented by the formulae (I) and (II) as defined herein. The composition has a viscosity (Kv100) from about 1 cSt to about 10 cSt at 100° C. as determined by ASTM D445, a viscosity index (VI) from about −100 to about 300 as determined by ASTM D2270, and a Noack volatility of no greater than 50 percent as determined by ASTM D5800. A process for producing the composition, a lubricating oil base stock and lubricating oil containing the composition, and a method for improving one or more of thermal and oxidative stability, solubility and dispersancy of polar additives, deposit control and traction control in a lubricating oil by using as the lubricating oil a formulated oil containing the composition.

8. 发明申请

US20170266250A1 COMPOSITIONS AND METHODS OF ANTIALLERGIC PHORBOL ESTER AND PHORBOL DERIVATIVES AS THE MAIN ACTIVE INGREDIENTS FROM THE SEEDS OF AQUILARIA MALACCENSIS 审中-公开
公开(公告)号：US20170266250A1
公开(公告)日：2017-09-21
申请号：US15180088
申请日：2016-06-13
申请人： WE-WIN APPLIED BIO-TECH CO., LTD.
发明人： FANG-RONG CHANG , BING-HUNG CHEN , HSUE-YIN HSU , YANG-CHANG WU , CHEN HSIEH , HUI-PING HSIEH
IPC分类号： A61K36/835 , C07C69/24 , A61K31/225 , A61K31/232 , A61K31/231
CPC分类号： A61K36/835 , A61K31/23 , A61K31/231 , A61K31/232 , A61K2236/333 , A61K2236/39 , C07C67/56 , C07C67/58 , C07C69/58 , C07C69/587 , C07C69/732 , C07C69/738 , C07C2603/40
摘要： The present invention relates to phorbol esters from the seeds of Aquilaria malaccensis by a series of chromatographic processes, and compositions containing these congeners for the treatment or prevention of allergic responses. Furthermore, compositions are provided which comprise these phorbol esters in combination with at least one to assess the effects for preventing or treating allergies.

9. 发明申请

US20160331661A1 NOVEL ESTER COMPOUND, AND COSMETIC COMPONENT AND COSMETIC PRODUCT EACH CONTAINING SAME 有权
标题翻译：新颖的化合物，和化妆品组分和每个包含其中的化妆品
公开(公告)号：US20160331661A1
公开(公告)日：2016-11-17
申请号：US15112462
申请日：2015-01-19
申请人： KOKYU ALCOHOL KOGYO CO., LTD.
发明人： Mari Masuno , Kiyotaka Kawai
IPC分类号： A61K8/37 , C07C69/013 , A61Q19/10 , C07C69/28 , A61Q1/04 , A61Q19/00 , A61Q17/04 , A61Q1/14 , A61Q5/00 , A61Q1/02 , C07C69/24 , A61Q1/06
CPC分类号： A61K8/37 , A61K2800/10 , A61K2800/262 , A61K2800/592 , A61Q1/00 , A61Q1/02 , A61Q1/04 , A61Q1/06 , A61Q1/10 , A61Q1/14 , A61Q5/00 , A61Q17/04 , A61Q19/00 , A61Q19/007 , A61Q19/10 , C07C69/013 , C07C69/24 , C07C69/28 , C07C2603/68
摘要： The purpose of the present invention is to provide a novel ester compound which can be used as a component of a cosmetic component. An ester compound of tricyclo[5.2.1.02,6]decane, which is represented by formula (I).
摘要翻译：本发明的目的是提供可用作化妆品组分的组分的新型酯化合物。由式（I）表示的三环[5.2.1.0 2,6]癸烷的酯化合物。

10. 发明申请

US20160280631A1 ESTER COMPOUNDS INCLUDING TRIESTERS HAVING TERMINAL VICINAL ACYL GROUPS 审中-公开
标题翻译：具有终端乙酸酯基团的酯的酯化合物
公开(公告)号：US20160280631A1
公开(公告)日：2016-09-29
申请号：US15073540
申请日：2016-03-17
申请人： BIOSYNTHETIC TECHNOLOGIES, LLC.
发明人： Jeremy FOREST
IPC分类号： C07C69/24 , C10M169/04 , C10M129/72
CPC分类号： C10M169/04 , C07C69/67 , C10M105/42 , C10M129/72 , C10M129/78 , C10M2207/282 , C10M2207/30 , C10M2207/301 , C10N2030/02 , C10N2230/02 , C10N2270/00
摘要： Provided herein are certain esters, including those of the Formula I: wherein z is an integer selected from 0 to 15; R1, independently for each occurrence, is an optionally substituted alkyl that is saturated or unsaturated, and branched or unbranched; and R2 is selected from hydrogen and optionally substituted alkyl that is saturated or unsaturated, and branched or unbranched. Hydroxy compounds are also described herein, which may be suitable end products, or serve as intermediates, to provide the desired ester products. Also described are compositions containing certain esters (e.g., triesters) and methods of making such esters and compositions thereof.
摘要翻译：其中z是选自0至15的整数; R1各自独立地为任选被取代的烷基，其为饱和或不饱和的，支链或非支链的; 并且R 2选自氢和任选取代的饱和或不饱和的烷基，并且是支链或非支链的。本文还描述了羟基化合物，其可以是合适的终产物，或用作中间体以提供所需的酯产物。还描述了含有某些酯（例如三酯）的组合物和制备这些酯及其组合物的方法。

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