专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US09757434B2 FXa variant compositions 有权
公开(公告)号：US09757434B2
公开(公告)日：2017-09-12
申请号：US14495478
申请日：2014-09-24
申请人： PFIZER INC.
发明人： Keith A. Johnson , Jason C. Rouse , Penelope Jane Sharpe , Stacey B. Weston , Michael Anthony Jankowski
IPC分类号： C12M1/20 , A61K38/48 , A61K38/36 , C12N9/64
CPC分类号： A61K38/4846 , A61K38/36 , C12N9/6432
摘要： Compositions are provided comprising recombinant variants of the human clotting Factor Xa. Such compositions include a wide variety of isoforms and post-translational modifications of FXa and are useful for treating subjects in need of hemostasis.

2. 发明申请

US20070212774A1 THERMOCYCLER WITH A TEMPERATURE CONTROL BLOCK DRIVEN IN CYCLES 有权
标题翻译：具有循环温度控制块的热电偶
公开(公告)号：US20070212774A1
公开(公告)日：2007-09-13
申请号：US11750745
申请日：2007-05-18
申请人： Kirsten Schicke , Claudia Hofmann
发明人： Kirsten Schicke , Claudia Hofmann
IPC分类号： C12M1/20 , C12Q1/68
CPC分类号： B01L7/54 , B01L7/52 , B01L2200/14 , B01L2300/0809 , B01L2300/1822
摘要： A thermocycler comprising a temperature control block (1,2,3) which is designed to receive several specimens and which is fitted with a control unit (6) that in consecutive cycles applies the different temperature levels (40° C., 70° C., 95° C.) of a PCR procedure to said block, said thermocycler being characterized in that said temperature controlling block is sub-divided into thermally separate segments (1,2,3) each of which is controlled separately and receives several specimens, the control unit (6) being designed to drive the said segments at different cycling rates (nine, seven, four).
摘要翻译：一种热循环器，包括温度控制块（1,2,3），其被设计成容纳几个试样并且配有控制单元（6），所述控制单元在连续循环中施加不同的温度水平（40℃，70℃ 所述热循环仪的特征在于，将所述温度控制块细分为热分离的片段（1,2,3），每个片段分别被控制并接收几个样品，所述控制单元（6）被设计成以不同的循环速率（九，七，四）驱动所述段。

3. 发明授权

US07118909B2 Apparatus and method for biomaterial assay 有权
公开(公告)号：US07118909B2
公开(公告)日：2006-10-10
申请号：US10146683
申请日：2002-05-15
申请人： Matthew R. Gevaert , Karen J. L. Burg
发明人： Matthew R. Gevaert , Karen J. L. Burg
IPC分类号： C12M3/00 , C12M1/20
CPC分类号： C12M25/04
摘要： An apparatus to facilitate precise and efficient evaluation of biomaterials using direct contact cell culture techniques. The apparatus positions the biomaterial and creates the potential to form a fluid-tight seal between the biomaterial and the apparatus, at which point the biomaterial is exposed to cells and/or media. An assay method based on the apparatus is claimed.

4. 发明授权

US06939709B2 Multi-well device 有权
标题翻译：多井装置
公开(公告)号：US06939709B2
公开(公告)日：2005-09-06
申请号：US10648662
申请日：2003-08-26
申请人： Douglas P. Henderson , Alan Trieber
发明人： Douglas P. Henderson , Alan Trieber
IPC分类号： C12M1/32 , B01L3/00 , C12M1/20 , C12M3/06 , C12M1/34
CPC分类号： B01L3/50255 , B01L3/5085 , B01L2200/026 , B01L2300/0829 , C12M25/04
摘要： A multi-well plate assembly has a well plate with a plurality of closed-bottom, open-top wells of substantially uniform square cross-section between the closed bottom and the open top. An insert plate is nested with the well plate and has a top wall substantially covering the open tops of the wells. Inserts project down from the top wall and into the respective wells, such that each insert is nested in a corner of the well. Access ports are formed through the insert plate for alignment with a corner of the respective well opposite the insert. The access port is formed partly through the top wall of the insert plate and partly through the sidewall of the insert.
摘要翻译：多孔板组件具有井板，其具有在封闭底部和开口顶部之间具有基本上均匀的正方形横截面的多个封闭底部开口井。插入板嵌套有孔板，并且具有基本覆盖井的开口顶部的顶壁。插入物从顶壁向下突出并进入相应的井，使得每个插入物嵌套在井的角落中。通过插入板形成进入口，用于与插入件相对的相应孔的角部对准。进入端口部分地穿过插入板的顶壁并且部分地穿过插入件的侧壁。

5. 发明授权

US6040153A Cartridge as well as air analysis method and apparatus using it 失效
标题翻译：墨盒以及使用它的空气分析方法和设备
公开(公告)号：US6040153A
公开(公告)日：2000-03-21
申请号：US283002
申请日：1999-03-31
申请人： Jean Lemonnier
发明人： Jean Lemonnier
IPC分类号： C12M1/34 , C12M1/20 , C12M1/26 , C12Q1/06 , C12Q1/24 , C12M3/00
CPC分类号： C12M41/36 , C12M23/10 , C12M23/38 , C12M23/42 , G01N1/2214
摘要： The cartridge has a body (2) with a grid (7) and an annular wall (8) oriented transversely to this grid and surrounding it, and having a layer (3) of growth media and a flexible fluid-tight film (4) tensioned over an end surface of the annular wall (8) and delimiting an end surface of the layer of growth media (3).According to the method, the surface of the layer of growth media (3) delimited at the time of manufacture by the tensioned film (4) is struck with air jets in order to impact on this surface the microorganisms present in the air.The apparatus has a positioning support common to a sieve for forming the air jets and to the body (2) of the cartridge (1).
摘要翻译：盒具有带有格栅（7）的主体（2）和横向于该格栅并围绕它的环形壁（8），并且具有生长介质层（3）和柔性流体密封膜（4）张紧在环形壁（8）的端表面上并限定生长介质层（3）的端表面。根据该方法，通过张紧膜（4）制造时限定的生长介质层（3）的表面被空气喷射，以便在该表面上影响存在于空气中的微生物。该装置具有与用于形成空气射流的筛子和筒体（1）的主体（2）通用的定位支撑件。

6. 发明授权

US5891739A Multiple sample container 失效
标题翻译：多个样品容器
公开(公告)号：US5891739A
公开(公告)日：1999-04-06
申请号：US495772
申请日：1995-06-27
申请人： Klaus W. Berndt
发明人： Klaus W. Berndt
IPC分类号： G01N1/10 , C12M1/20 , C12M1/34 , C12Q1/04 , G01N1/14 , C12M1/24 , C12M1/40 , G01N15/06
CPC分类号： C12M23/12 , C12M23/22 , C12M23/26 , C12M23/38 , C12M41/36 , C12M41/46 , Y10S436/807 , Y10S436/809
摘要： The present invention describes a multiple sample container for use in a method and apparatus for detecting microorganisms in a culture container. The container includes a block having a plurality of through holes for dividing the sample into a plurality of partial samples. Each partial sample has its own head space and its own sensor. The spacial array of partial samples is read out by a CCD camera and split into partial sample to generate a spacial array that results in a substantial reduction in the time to detection.
摘要翻译：本发明描述了用于检测培养容器中的微生物的方法和装置中的多个样品容器。容器包括具有多个通孔的块，用于将样品分成多个部分样品。每个部分样本都有自己的头部空间和自己的传感器。部分样本的空间阵列由CCD相机读出并分割成部分样本，以产生导致检测时间显着减少的空间阵列。

7. 发明授权

US5792654A Microorganism culture tray 失效
标题翻译：微生物培养皿
公开(公告)号：US5792654A
公开(公告)日：1998-08-11
申请号：US967512
申请日：1997-11-11
申请人： Lon Maynard Bohannon , Raymond Louis Miller , Sudhakar Vulimiri
发明人： Lon Maynard Bohannon , Raymond Louis Miller , Sudhakar Vulimiri
IPC分类号： B01L3/00 , C12M1/20 , C12M3/00 , B65D51/18
CPC分类号： B01L3/5085 , C12M23/04 , C12M23/12 , C12M23/22 , C12M23/38 , C12M41/36 , C12M23/10
摘要： A microorganism culture tray (10) including a cover (11) and base (12) are described. The base and cover have polygonal preferably hexagonal, walls (14, 15) which allow the cover to be mounted on the base either opening a recess (17) or closing the recess.
摘要翻译：描述了包括盖（11）和基底（12）的微生物培养托盘（10）。基座和盖具有多边形，优选为六边形，壁（14,15），其允许盖安装在基座上，以打开凹部（17）或闭合凹部。

8. 发明授权

US5652142A Cell culture insert 失效
标题翻译：细胞培养插入物
公开(公告)号：US5652142A
公开(公告)日：1997-07-29
申请号：US535368
申请日：1995-09-28
申请人： Susan Barker , I-Hsi Chu , Oresta N. Fedun , Tadeusz A. Tyndorf
发明人： Susan Barker , I-Hsi Chu , Oresta N. Fedun , Tadeusz A. Tyndorf
IPC分类号： C12M1/20 , C12M1/12 , C12M3/00 , C12M3/04 , C12M3/06
CPC分类号： C12M25/04
摘要： Apparatus for growing cells or tissue in vitro, which permits a concentration gradient of nutrients to develop through a permeable membrane to which a sample of tissue is attached. The permeable membrane is attached to the bottom end of a cell culture insert that in turn is supported by a flange connected to its upper end on the top of a well containing the nutrients. Restricted movement of the cell culture insert in the well may be facilitated by projections extending off the outer wall surface of the insert so as to avoid capillary action in the space between the well and the insert.
摘要翻译：用于在体外生长细胞或组织的装置，其允许营养物的浓度梯度通过附着有组织样品的渗透膜显影。渗透膜连接到细胞培养插入物的底端，细胞培养插入物的底端又由连接到其含有营养物的孔的顶部上端的凸缘支撑。可以通过从插入件的外壁表面延伸的突起来促进细胞培养插入物在孔中的限制运动，以避免孔与插入物之间的空间中的毛细管作用。

9. 发明授权

US5543327A Apparatus for conducting the cytotoxicity assays on tumor cells 失效
标题翻译：用于对肿瘤细胞进行细胞毒性测定的装置
公开(公告)号：US5543327A
公开(公告)日：1996-08-06
申请号：US279311
申请日：1994-07-22
申请人： Yu P. Yen-Maguire , Tom Cox , Fred Lewis
发明人： Yu P. Yen-Maguire , Tom Cox , Fred Lewis
IPC分类号： C12M1/20 , G01N33/50 , C12M1/34 , C12Q1/18 , C12Q1/20
CPC分类号： C12M23/12 , C12M25/14 , C12M41/46 , G01N33/5011 , G01N2800/52 , Y10S435/81
摘要： A method and apparatus for assaying the sensitivity of biopsied tumor cells to chemotherapeutic agents using a predetermined amount of chemotherapeutic agent in an easily deliverable form is disclosed and claimed.
摘要翻译：公开和要求保护的方法和装置，用于使用预定量的化学治疗剂以易于递送的形式测定活检肿瘤细胞对化学治疗剂的敏感性。

10. 发明授权

US5518920A Biological treatment of hazardous waste 失效
标题翻译：生物处理危险废物
公开(公告)号：US5518920A
公开(公告)日：1996-05-21
申请号：US212250
申请日：1994-03-14
申请人： William C. Stewart , Randall R. Thom
发明人： William C. Stewart , Randall R. Thom
IPC分类号： A62D3/00 , A62D3/02 , B01D53/85 , B01D53/34 , C12M1/20 , C12M1/14 , B09B3/00
CPC分类号： B01D53/85 , B09B3/00
摘要： Apparatus for treatment of material containing biodegradable volatile organic compounds in solid or liquid state, comprises a first chamber having a gas inlet and a gas outlet, the gas inlet being below the gas outlet. Material to be treated is supported in the first chamber between the gas inlet and the gas outlet. The material to be treated is warmed and an upward flow of air is established in the first chamber whereby biodegradable volatile organic compounds in the material are volatilized and become entrained in the upward flow of air. A second chamber has a gas inlet and a gas outlet, the gas inlet of the second chamber being below the gas outlet thereof. A duct delivers gas from the gas outlet of the first chamber to the gas inlet of the second chamber. A biologically active matrix including at least one organism that biologically converts the organic compounds to a non-toxic form is supported in the second chamber between the gas inlet and the gas outlet thereof.
摘要翻译：用于处理含有固体或液体状态的可生物降解的挥发性有机化合物的材料的装置包括具有气体入口和气体出口的第一室，气体入口位于气体出口下方。要处理的材料被支撑在气体入口和气体出口之间的第一室中。要处理的材料被加热并且在第一室中建立向上的空气流，由此材料中的生物可降解的挥发性有机化合物挥发并且被夹带在向上的空气流中。第二室具有气体入口和气体出口，第二室的气体入口位于其气体出口的下方。管道将气体从第一室的气体出口传送到第二室的气体入口。在气体入口和其气体出口之间的第二室中支撑包括生物转化有机化合物至无毒形式的至少一种生物体的生物活性基质。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式